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PROSITE entry PS00511


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General information about the entry

Entry name [info] CRF
Accession [info] PS00511
Entry type [info] PATTERN
Date [info] 01-JUN-1991 CREATED;
01-JUL-1999 DATA UPDATE;
24-JAN-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00442

Name and characterization of the entry

Description [info] Corticotropin-releasing factor family signature.
Pattern [info]
[PQA]-x-[LIVM]-S-[LIVM]-x(2)-[PST]-[LIVMF]-x-[LIVM]-L-R-x(2)-[LIVMW].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_01 which contains 570'830 sequence entries.


Total number of hits 42 in 42 different sequences
Number of true positive hits 35 in 35 different sequences
Number of 'unknown' hits 0
Number of false positive hits 7 in 7 different sequences
Number of false negative sequences 3
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 83.33 %
Recall (true positives / (true positives + false negatives)) 92.11 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
35 sequences

CRF1_CATCO  (P13241), CRF2_CATCO  (P25308), CRF_BOVIN   (Q95MI6), 
CRF_CANLF   (P49926), CRF_CARAU   (Q9PTS1), CRF_HUMAN   (P06850), 
CRF_MOUSE   (Q8CIT0), CRF_PIG (P06296), CRF_RAT (P01143), 
CRF_SHEEP   (P01142), CRF_XENLA   (P49188), DIH41_AGRIP (C0HKT4), 
DIH41_BOMMO (B3IUD8), DIH45_AGRIP (C0HKT5), DIH45_BOMMO (B3IUE0), 
DIUH1_HYLLI (P82014), DIUH1_MANSE (P21819), DIUH1_TENMO (P56618), 
DIUH2_TENMO (P56619), DIUH_ACHDO  (P23834), DIUH_DIPPU  (P82373), 
DIUH_LOCMI  (P23465), DIUH_MUSDO  (P67800), DIUH_PERAM  (P41538), 
DIUH_STOCA  (P67801), DIUH_ZOONE  (P82707), SAUV_PHYSA  (P01144), 
UCN1_HUMAN  (P55089), UCN1_MOUSE  (P81615), UCN1_RAT(P55090), 
UTS1_CARAU  (Q9PTQ4), UTS1_CATCO  (P01145), UTS1_CYPCA  (P01146), 
UTS1_ONCMY  (O93448), UTS1_PLAFE  (P21624)
» more

UniProtKB/Swiss-Prot
False negative sequences
3 sequences

DIH44_CAMFO (E2A6P1), DIUH2_HYLLI (P82015), DIUH2_MANSE (P24858)

		
UniProtKB/Swiss-Prot
False positive sequences
7 sequences

ZITB_ECO57  (Q8X400), ZITB_ECOLI  (P75757), ZITB_SALTI  (Q8Z8B6), 
ZITB_SALTY  (Q8ZQT3), ZITB_SHIFL  (Q83SA2), ZITB_YERPE  (Q8ZGY6), 
ZITB_YERPS  (Q66D85)
» more

PDB
[Detailed view]
6 PDB

2RMF; 6P9X; 6PB0; 6PB1; 7TRY; 7TS0