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PROSITE entry PS00520


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00520
Entry name [info] INTERLEUKIN_10
Accession [info] PS00520
Entry type [info] PATTERN
Date [info] 01-DEC-1991 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00450

Name and characterization of the entry

Description [info] Interleukin-10 family signature.
Pattern [info] 
[KQS]-x(4)-C-[QYCS]-x(4)-[LIVM](2)-x-[FLR]-[FYT]-[LMVR]-x-[DERTI]-[IV]-
[LMF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 45 in 45 different sequences
Number of true positive hits 45 in 45 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 1
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 97.83 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] disulfide at position 3
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 45 sequences 

IL10H_EBVA8 (P0C6Z6), IL10H_EBVB9 (P03180), IL10H_EBVG  (P0CAP9), 

IL10H_EHV2  (P68678), IL10H_EHV2T (P68677), IL10H_HCMVA (P17150), 
IL10H_HCMVM (F5HC71), IL10_BOVIN  (P43480), IL10_BUBCA  (Q2PE73), 
IL10_CALJA  (Q0Z972), IL10_CANLF  (P48411), IL10_CAVPO  (Q9Z1Y5), 
IL10_CERAT  (P46651), IL10_CEREL  (P51746), IL10_FELCA  (P55029), 
IL10_HORSE  (Q28374), IL10_HUMAN  (P22301), IL10_LAMGL  (Q865X4), 
IL10_MACFA  (P79338), IL10_MACMU  (P51496), IL10_MACNE  (P51497), 
IL10_MARMO  (Q9JHK7), IL10_MERUN  (P47965), IL10_MOUSE  (P18893), 
IL10_ORCOR  (O46673), IL10_PANTR  (A2T6Z6), IL10_PAPHA  (Q5Q0V6), 
IL10_PIG(Q29055), IL10_RABIT  (Q9TSJ4), IL10_RAT(P29456), 
IL10_SAISC  (Q8MKG9), IL10_SHEEP  (Q29408), IL10_TRIVU  (O97798), 
IL10_VULVU  (Q25BC1), IL19_HUMAN  (Q9UHD0), IL19_MOUSE  (Q8CJ70), 
IL20_HUMAN  (Q9NYY1), IL20_MOUSE  (Q9JKV9), IL22B_MOUSE (Q9JJY8), 
IL22_HUMAN  (Q9GZX6), IL22_MOUSE  (Q9JJY9), IL24_HUMAN  (Q13007), 
IL24_MOUSE  (Q925S4), IL24_RAT(Q9JI24), IL26_HUMAN  (Q9NPH9)
» more

UniProtKB/Swiss-Prot
False negative sequences		 1 sequence 

IL10_CHICK  (Q6A2H4)


				
	

	

		PDB
[Detailed view]		
		
			25 PDB
			


			1ILK; 1INR; 1J7V; 1LK3; 1LQS; 1M4R; 1N1F; 1VLK; 1Y6K; 1Y6M; 1Y6N; 1YKB; 
			
				2H24; 2ILK; 3DGC; 3DLQ; 3G9V; 3Q1S; 4DOH; 4X51; 6DF3; 6GG1; 6WEO; 6X93; 
				8SVE
			
			

			» more