PROSITE entry PS00520

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PURL: https://purl.expasy.org/prosite/signature/PS00520

Direct ScanProsite submission

General information about the entry

Entry name [info]	INTERLEUKIN_10
Accession [info]	PS00520
Entry type [info]	PATTERN
Date [info]	01-DEC-1991 CREATED; 01-APR-2006 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00450

Name and characterization of the entry

Description [info]	Interleukin-10 family signature.
Pattern [info]	[KQS]-x(4)-C-[QYCS]-x(4)-[LIVM](2)-x-[FLR]-[FYT]-[LMVR]-x-[DERTI]-[IV]- [LMF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.

Total number of hits	45 in 45 different sequences
Number of true positive hits	45 in 45 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	1
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	97.83 %

Comments [info]

Taxonomic range [info]	Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info]	1
Site [info]	disulfide at position 3
Version [info]	2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

45 sequences

IL10H_EBVA8 (P0C6Z6), IL10H_EBVB9 (P03180), IL10H_EBVG  (P0CAP9),

IL10H_EHV2  (P68678), IL10H_EHV2T (P68677), IL10H_HCMVA (P17150), 
IL10H_HCMVM (F5HC71), IL10_BOVIN  (P43480), IL10_BUBCA  (Q2PE73), 
IL10_CALJA  (Q0Z972), IL10_CANLF  (P48411), IL10_CAVPO  (Q9Z1Y5), 
IL10_CERAT  (P46651), IL10_CEREL  (P51746), IL10_FELCA  (P55029), 
IL10_HORSE  (Q28374), IL10_HUMAN  (P22301), IL10_LAMGL  (Q865X4), 
IL10_MACFA  (P79338), IL10_MACMU  (P51496), IL10_MACNE  (P51497), 
IL10_MARMO  (Q9JHK7), IL10_MERUN  (P47965), IL10_MOUSE  (P18893), 
IL10_ORCOR  (O46673), IL10_PANTR  (A2T6Z6), IL10_PAPHA  (Q5Q0V6), 
IL10_PIG(Q29055), IL10_RABIT  (Q9TSJ4), IL10_RAT(P29456), 
IL10_SAISC  (Q8MKG9), IL10_SHEEP  (Q29408), IL10_TRIVU  (O97798), 
IL10_VULVU  (Q25BC1), IL19_HUMAN  (Q9UHD0), IL19_MOUSE  (Q8CJ70), 
IL20_HUMAN  (Q9NYY1), IL20_MOUSE  (Q9JKV9), IL22B_MOUSE (Q9JJY8), 
IL22_HUMAN  (Q9GZX6), IL22_MOUSE  (Q9JJY9), IL24_HUMAN  (Q13007), 
IL24_MOUSE  (Q925S4), IL24_RAT(Q9JI24), IL26_HUMAN  (Q9NPH9)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

1 sequence

IL10_CHICK  (Q6A2H4)

PDB
[Detailed view]

25 PDB

pdb_00001ilk; pdb_00001inr; pdb_00001j7v; pdb_00001lk3; pdb_00001lqs; pdb_00001m4r; pdb_00001n1f; pdb_00001vlk; pdb_00001y6k; pdb_00001y6m; pdb_00001y6n; pdb_00001ykb; pdb_00002h24; pdb_00002ilk; pdb_00003dgc; pdb_00003dlq; pdb_00003g9v; pdb_00003q1s; pdb_00004doh; pdb_00004x51; pdb_00006df3; pdb_00006gg1; pdb_00006weo; pdb_00006x93; pdb_00008sve
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