PROSITE entry PS00521

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS00521
Entry name [info]	P5CR
Accession [info]	PS00521
Entry type [info]	PATTERN
Date [info]	01-DEC-1991 CREATED; 01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00451

Name and characterization of the entry

Description [info]	Delta 1-pyrroline-5-carboxylate reductase signature.
Pattern [info]	[PALF]-x(2,3)-[LIV]-x(3)-[LIVM]-[STAC]-[STV]-x-[GANK]-G-x-T-x(2)-[AG]- [LIV]-x(2)-[LMF]-[DENQK].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	50 in 50 different sequences
Number of true positive hits	50 in 50 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	16
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	75.76 %

Comments [info]

Taxonomic range [info]	Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

50 sequences

COMER_BACSU (P39696), KK1I_CURCL  (A0A348AXY1), P5CR1_ARATH (P54904),

P5CR1_BACSH (E0TY11), P5CR1_BACSU (P0CI77), P5CR1_BOVIN (Q58DT4), 
P5CR1_HUMAN (P32322), P5CR1_MOUSE (Q922W5), P5CR1_PONAB (Q5R9X6), 
P5CR2_BACSU (P54552), P5CR2_BOVIN (Q17QJ7), P5CR2_HUMAN (Q96C36), 
P5CR2_MACFA (Q4R6W7), P5CR2_MOUSE (Q922Q4), P5CR2_PONAB (Q5RAQ3), 
P5CR2_RAT   (Q6AY23), P5CR3_BOVIN (Q58D08), P5CR3_DANRE (Q5SPD7), 
P5CR3_HUMAN (Q53H96), P5CR3_MACFA (Q4R531), P5CR3_XENLA (A1L2Q8), 
P5CR4_CAEEL (Q20848), P5CR_ACTCC  (O04016), P5CR_AQUAE  (O66553), 
P5CR_CORGL  (P0C1E4), P5CR_CORML  (P0C1E5), P5CR_ECOLI  (P0A9L8), 
P5CR_HAEIN  (P43869), P5CR_HELPJ  (Q9ZK56), P5CR_HELPY  (O25773), 
P5CR_KLULA  (Q6CR99), P5CR_LOPAR  (Q12740), P5CR_METAC  (Q9HH99), 
P5CR_METSM  (P22350), P5CR_MYCLE  (P46725), P5CR_MYCTO  (P9WHU6), 
P5CR_MYCTU  (P9WHU7), P5CR_NEUCR  (Q12641), P5CR_PASMU  (Q9CPE8), 
P5CR_PEA(Q04708), P5CR_PSEAE  (P22008), P5CR_SCHPO  (Q9P7Y7), 
P5CR_SHIFL  (P0A9L9), P5CR_SOYBN  (P17817), P5CR_SYNY3  (P74572), 
P5CR_THET2  (P54893), P5CR_TREPA  (P27771), P5CR_VIBAL  (P52053), 
P5CR_YEAST  (P32263), PHQD_PENFE  (L0E163)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

16 sequences

NXRD1_HUMAN (Q6NXP6), NXRD1_MOUSE (Q9D3S5), NXRD1_XENTR (A0JM24),

P5CR3_BACSU (Q00777), P5CR3_MOUSE (Q9DCC4), P5CR3_RAT   (Q5PQJ6), 
P5CR_STAAC  (Q5HFR9), P5CR_STAAM  (Q99TZ0), P5CR_STAAN  (Q7A5G8), 
P5CR_STAAR  (Q6GGJ5), P5CR_STAAS  (Q6G961), P5CR_STAAW  (Q7A0U1), 
P5CR_STAEQ  (Q5HP48), P5CR_STAES  (Q8CP51), P5CR_STAHJ  (Q4L6K3), 
P5CR_STAS1  (Q49XV0)

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PDB
[Detailed view]

36 PDB

2GER; 2GR9; 2GRA; 2IZZ; 5UAT; 5UAU; 5UAV; 5UAW; 5UAX; 6LHM; 6XOZ; 6XP0; 6XP1; 6XP2; 6XP3; 8DKG; 8TCU; 8TCV; 8TCW; 8TCX; 8TCY; 8TCZ; 8TD0; 8TD1; 8TD2; 8TD3; 8TD4; 8TD5; 8TD6; 8TD7; 8TD8; 8TD9; 8TDB; 8TDC; 8TDD; 8VRE
» more