PROSITE entry PS00521

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General information about the entry

Entry name [info]	P5CR
Accession [info]	PS00521
Entry type [info]	PATTERN
Date [info]	01-DEC-1991 CREATED; 01-DEC-2004 DATA UPDATE; 13-SEP-2023 INFO UPDATE.
PROSITE Doc. [info]	PDOC00451

Name and characterization of the entry

Description [info]	Delta 1-pyrroline-5-carboxylate reductase signature.
Pattern [info]	[PALF]-x(2,3)-[LIV]-x(3)-[LIVM]-[STAC]-[STV]-x-[GANK]-G-x-T-x(2)-[AG]- [LIV]-x(2)-[LMF]-[DENQK].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2023_04 which contains 570'157 sequence entries.

Total number of hits	50 in 50 different sequences
Number of true positive hits	50 in 50 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	16
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	75.76 %

Comments [info]

Taxonomic range [info]	Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

50 sequences

COMER_BACSU (P39696), P5CR1_ARATH (P54904), P5CR1_BACSH (E0TY11),

P5CR1_BACSU (P0CI77), P5CR1_BOVIN (Q58DT4), P5CR1_HUMAN (P32322), 
P5CR1_MOUSE (Q922W5), P5CR1_PONAB (Q5R9X6), P5CR2_BACSU (P54552), 
P5CR2_BOVIN (Q17QJ7), P5CR2_HUMAN (Q96C36), P5CR2_MACFA (Q4R6W7), 
P5CR2_MOUSE (Q922Q4), P5CR2_PONAB (Q5RAQ3), P5CR2_RAT   (Q6AY23), 
P5CR3_BOVIN (Q58D08), P5CR3_DANRE (Q5SPD7), P5CR3_HUMAN (Q53H96), 
P5CR3_MACFA (Q4R531), P5CR3_XENLA (A1L2Q8), P5CR_ACTCC  (O04016), 
P5CR_AQUAE  (O66553), P5CR_CAEEL  (Q20848), P5CR_CORGL  (P0C1E4), 
P5CR_CORML  (P0C1E5), P5CR_ECOLI  (P0A9L8), P5CR_HAEIN  (P43869), 
P5CR_HELPJ  (Q9ZK56), P5CR_HELPY  (O25773), P5CR_KLULA  (Q6CR99), 
P5CR_LOPAR  (Q12740), P5CR_METAC  (Q9HH99), P5CR_METSM  (P22350), 
P5CR_MYCLE  (P46725), P5CR_MYCTO  (P9WHU6), P5CR_MYCTU  (P9WHU7), 
P5CR_NEUCR  (Q12641), P5CR_PASMU  (Q9CPE8), P5CR_PEA(Q04708), 
P5CR_PSEAE  (P22008), P5CR_SCHPO  (Q9P7Y7), P5CR_SHIFL  (P0A9L9), 
P5CR_SOYBN  (P17817), P5CR_SYNY3  (P74572), P5CR_THET2  (P54893), 
P5CR_TREPA  (P27771), P5CR_VIBAL  (P52053), P5CR_YEAST  (P32263), 
PHQD_PENFE  (L0E163), TR08_CURCL  (A0A348AXY1)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

16 sequences

NXRD1_HUMAN (Q6NXP6), NXRD1_MOUSE (Q9D3S5), NXRD1_XENTR (A0JM24),

P5CR3_BACSU (Q00777), P5CR3_MOUSE (Q9DCC4), P5CR3_RAT   (Q5PQJ6), 
P5CR_STAAC  (Q5HFR9), P5CR_STAAM  (Q99TZ0), P5CR_STAAN  (Q7A5G8), 
P5CR_STAAR  (Q6GGJ5), P5CR_STAAS  (Q6G961), P5CR_STAAW  (Q7A0U1), 
P5CR_STAEQ  (Q5HP48), P5CR_STAES  (Q8CP51), P5CR_STAHJ  (Q4L6K3), 
P5CR_STAS1  (Q49XV0)

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PDB
[Detailed view]

16 PDB

2GER; 2GR9; 2GRA; 2IZZ; 5UAT; 5UAU; 5UAV; 5UAW; 5UAX; 6LHM; 6XOZ; 6XP0; 6XP1; 6XP2; 6XP3; 8DKG
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