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PROSITE entry PS00544


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00544
Entry name [info] METMALONYL_COA_MUTASE
Accession [info] PS00544
Entry type [info] PATTERN
Date [info] 01-DEC-1991 CREATED;
01-DEC-2001 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00470

Name and characterization of the entry

Description [info] Methylmalonyl-CoA mutase signature.
Pattern [info] 
R-I-A-R-N-[TQ]-x(2)-[LIVMFY](2)-x-[EQH]-E-x(4)-[KRN]-x(2)-D-P-x-[GSA]-
G-S.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 22 in 22 different sequences
Number of true positive hits 22 in 22 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 2
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 91.67 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 22 sequences 

MCM_CERS4   (Q3J4D7), MCM_RHIME   (O86028), MUTA_BOVIN  (Q9GK13), 

MUTA_CAEEL  (Q23381), MUTA_HUMAN  (P22033), MUTA_MACFA  (Q8HXX1), 
MUTA_MOUSE  (P16332), MUTA_MYCBO  (P65486), MUTA_MYCTO  (P9WJK6), 
MUTA_MYCTU  (P9WJK7), MUTA_PIG(Q8MI68), MUTA_PONAB  (Q5RFN2), 
MUTA_PORGI  (Q59676), MUTA_PROFR  (P11652), MUTA_STRVG  (Q05064), 
MUTB_MYCBO  (P65488), MUTB_MYCTO  (P9WJK4), MUTB_MYCTU  (P9WJK5), 
MUTB_PORGI  (Q59677), MUTB_PROFR  (P11653), MUTB_STRVG  (Q05065), 
SCPA_ECOLI  (P27253)
» more

UniProtKB/Swiss-Prot
False negative sequences		 2 sequences 

ECM_CERS4   (Q3IZ90), ECM_METEA   (Q49115)


				
	

	

		PDB
[Detailed view]		
		
			16 PDB
			


			1E1C; 1REQ; 2REQ; 2XIJ; 2XIQ; 3BIC; 3REQ; 4REQ; 5REQ; 6OXC; 6OXD; 6REQ; 
			
				7REQ; 8DYJ; 8DYL; 8GJU
			
			

			» more