PROSITE entry PS00557

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PURL: https://purl.expasy.org/prosite/signature/PS00557

Direct ScanProsite submission

General information about the entry

Entry name [info]	FMN_HYDROXY_ACID_DH_1
Accession [info]	PS00557
Entry type [info]	PATTERN
Date [info]	01-DEC-1991 CREATED; 01-DEC-1991 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00482
Associated ProRule [info]	PRU00683

Name and characterization of the entry

Description [info]	FMN-dependent alpha-hydroxy acid dehydrogenases active site.
Pattern [info]	S-N-H-G-[AG]-R-Q.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2026_01 which contains 574'627 sequence entries.

Total number of hits	154 in 154 different sequences
Number of true positive hits	154 in 154 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	8
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	95.06 %

Comments [info]

Taxonomic range [info]	Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Site [info]	active_site at position 3
Site [info]	substrate_binding at position 6
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

154 sequences

COCF_COCIM  (J3KAR9), CYB2_WICAO  (P09437), CYB2_YEAST  (P00175),

FUB9_FUSO4  (A0A0D2YG00), FUB9_GIBF5  (S0DRI9), FUB9_GIBM7  (W7NCP1), 
GLO1_ARATH  (Q9LRR9), GLO1_ORYSI  (B8AKX6), GLO1_ORYSJ  (Q10CE4), 
GLO2_ARATH  (Q9LRS0), GLO2_ORYSI  (Q01KC2), GLO2_ORYSJ  (Q7XPR4), 
GLO3_ORYSI  (B8AUI3), GLO3_ORYSJ  (Q7FAS1), GLO5_ARATH  (O49506), 
GLO5_ORYSI  (B8B7C5), GLO5_ORYSJ  (Q6YT73), GOX1_MAIZE  (A0A3L6E0R4), 
GOX_SPIOL   (P05414), HAOX1_ARATH (Q9LJH5), HAOX1_HUMAN (Q9UJM8), 
HAOX1_MOUSE (Q9WU19), HAOX1_RAT   (B0BNF9), HAOX2_ARATH (Q24JJ8), 
HAOX2_BOVIN (Q3ZBW2), HAOX2_HUMAN (Q9NYQ3), HAOX2_MOUSE (Q9NYQ2), 
HAOX2_RAT   (Q07523), HAOX_DICDI  (Q54E41), HAOX_ORYSI  (B8B8K5), 
HAOX_ORYSJ  (Q8H3I4), HMO_AMYOR   (O52792), LLDD_ACIAD  (Q6FFS1), 
LLDD_ACIB3  (B7H2H0), LLDD_ACIB5  (B7IBS4), LLDD_ACIBC  (B2I061), 
LLDD_ACIBS  (B0VND0), LLDD_ACIBT  (A3M0X0), LLDD_ACIBY  (B0V6L1), 
LLDD_ACTP2  (A3N3E5), LLDD_ACTP7  (B3GZA5), LLDD_ACTPJ  (B0BTC7), 
LLDD_ALCFA  (Q6WB83), LLDD_ALLAM  (B9K115), LLDD_AZOC5  (A8HTC9), 
LLDD_BARHE  (Q6G4R2), LLDD_BARQU  (Q6G0J2), LLDD_BART1  (A9IN89), 
LLDD_CAUSK  (B0T7X2), LLDD_CAUVC  (Q9A943), LLDD_CAUVN  (B8H3Q5), 
LLDD_CHRI1  (Q1R0J2), LLDD_CITK8  (A8ARJ1), LLDD_CROS8  (A7MNF6), 
LLDD_ECO24  (A7ZTF9), LLDD_ECO27  (B7ULG1), LLDD_ECO45  (B7MFG9), 
LLDD_ECO55  (B7L725), LLDD_ECO57  (Q8XDF7), LLDD_ECO5E  (B5YWA7), 
LLDD_ECO7I  (B7NPB4), LLDD_ECO81  (B7N251), LLDD_ECO8A  (B7M492), 
LLDD_ECOBW  (C4ZXJ7), LLDD_ECODH  (B1X8M0), LLDD_ECOHS  (A8A670), 
LLDD_ECOK1  (A1AHE2), LLDD_ECOL5  (Q0TBK1), LLDD_ECOL6  (Q8FCB1), 
LLDD_ECOLC  (B1IZI5), LLDD_ECOLI  (P33232), LLDD_ECOLU  (B7NER0), 
LLDD_ECOSE  (B6I3I4), LLDD_ECOSM  (B1LK44), LLDD_ECOUT  (Q1R4Z0), 
LLDD_ECTM1  (A4XYG7), LLDD_ENT38  (A4W540), LLDD_ESCF3  (B7LTL2), 
LLDD_HAEDU  (Q7VPI9), LLDD_HAEI8  (Q4QJK8), LLDD_HAEIE  (A5UBE3), 
LLDD_HAEIG  (A5UFG9), LLDD_HAEIN  (P46454), LLDD_KLEP7  (A6TFK0), 
LLDD_KLEV3  (B5XMV0), LLDD_MYCTO  (P9WND4), LLDD_MYCTU  (P9WND5), 
LLDD_PECAS  (Q6DAY3), LLDD_PSEA8  (B7V1I3), LLDD_PSEAB  (Q02FQ1), 
LLDD_PSEAE  (Q9HV37), LLDD_PSEE4  (Q1IF69), LLDD_PSEFS  (C3K053), 
LLDD_PSEP1  (A5W9B2), LLDD_PSEP7  (A6VCM8), LLDD_PSEPG  (B0KIT4), 
LLDD_PSEPK  (Q88DT3), LLDD_PSEPW  (B1J244), LLDD_PSEU2  (Q4ZY06), 
LLDD_SALA4  (B5EXA8), LLDD_SALAR  (A9MLC3), LLDD_SALCH  (Q57ID8), 
LLDD_SALDC  (B5FLH2), LLDD_SALEP  (B5R5C7), LLDD_SALG2  (B5RGI4), 
LLDD_SALHS  (B4T986), LLDD_SALNS  (B4SXA4), LLDD_SALPA  (Q5PLQ7), 
LLDD_SALPB  (A9MVJ5), LLDD_SALPC  (C0Q1T7), LLDD_SALPK  (B5BHX7), 
LLDD_SALSV  (B4TZU7), LLDD_SALTI  (Q8Z2E5), LLDD_SALTY  (Q8ZL61), 
LLDD_SERP5  (A8GIL1), LLDD_SHIB3  (B2U5C2), LLDD_SHIBS  (Q31V17), 
LLDD_SHIDS  (Q329P9), LLDD_SHIF8  (Q0SYD1), LLDD_SHIFL  (Q83PP7), 
LLDD_SHISS  (Q3YVX0), LLDD_STRM5  (B4SMK1), LLDD_STRMK  (B2FIJ0), 
LLDD_VIBCH  (Q9KKW6), LLDD_VIBCM  (C3LWP7), LLDD_VIBPA  (Q87G18), 
LLDD_XANAC  (Q8PR33), LLDD_XANC8  (Q4V0H2), LLDD_XANCB  (B0RLM2), 
LLDD_XANCP  (Q8PE75), LLDD_XANE5  (Q3BZH2), LLDD_XANOM  (Q2P9K0), 
LLDD_XANOP  (B2SUY3), LLDD_XANOR  (Q5H6Z4), LLDD_XANP2  (A7IMB0), 
LLDD_YERP3  (A7FJF0), LLDD_YERPA  (Q1C9P0), LLDD_YERPB  (B2JZQ1), 
LLDD_YERPE  (Q8ZFV8), LLDD_YERPG  (A9R623), LLDD_YERPN  (Q1CGZ1), 
LLDD_YERPP  (A4TKI4), LLDD_YERPS  (Q66C32), LLDD_YERPY  (B1JPU0), 
LMO_MYCSM   (P21795), LOX_AERVM   (Q44467), LOX_CHLRE   (F8WQN2), 
LOX_LACRM   (C2K1F0), LOX_LENH9   (C0XIJ3), LOX_LYSSC   (B1HZY7), 
LOX_NOSS1   (Q8Z0C8), MDLB_PSEPU  (P20932), QULF_PENCI  (P0DUR7), 
YKN3_SCHPO  (Q9HDX2)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

8 sequences

CYB2_TALSN  (B8MKR3), CYBL_RHOGR  (P32953), LOX_ALIDK   (F4G5A4),

LOX_LACJE   (A0A5N1I561), LOX_ROSS0   (B7RR92), LOX_STRIN   (O33655), 
MFTD_MYCTO  (P9WND6), MFTD_MYCTU  (P9WND7)

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PDB
[Detailed view]

101 PDB

pdb_00001al7; pdb_00001al8; pdb_00001fcb; pdb_00001gox; pdb_00001gyl; pdb_00001huv; pdb_00001kbi; pdb_00001kbj; pdb_00001lco; pdb_00001ldc; pdb_00001ltd; pdb_00001p4c; pdb_00001p5b; pdb_00001qcw; pdb_00001sze; pdb_00001szf; pdb_00001szg; pdb_00001tb3; pdb_00002a7n; pdb_00002a7p; pdb_00002a85; pdb_00002du2; pdb_00002e77; pdb_00002j6x; pdb_00002nli; pdb_00002nzl; pdb_00002rdt; pdb_00002rdu; pdb_00002rdw; pdb_00002w0u; pdb_00002zfa; pdb_00003giy; pdb_00003sgz; pdb_00004rje; pdb_00004yl2; pdb_00005ebu; pdb_00005qib; pdb_00005qic; pdb_00005qid; pdb_00005qie; pdb_00005qif; pdb_00005qig; pdb_00005qih; pdb_00005zzp; pdb_00005zzq; pdb_00005zzr; pdb_00005zzs; pdb_00005zzt; pdb_00005zzx; pdb_00005zzy; pdb_00005zzz; pdb_00006a00; pdb_00006a01; pdb_00006a08; pdb_00006a0b; pdb_00006a0d; pdb_00006a0g; pdb_00006a0m; pdb_00006a0o; pdb_00006a0v; pdb_00006a0y; pdb_00006a11; pdb_00006a13; pdb_00006a19; pdb_00006a1a; pdb_00006a1b; pdb_00006a1h; pdb_00006a1l; pdb_00006a1m; pdb_00006a1n; pdb_00006a1p; pdb_00006a1r; pdb_00006a1w; pdb_00006a21; pdb_00006a23; pdb_00006a24; pdb_00006a36; pdb_00006a39; pdb_00006a3d; pdb_00006a3t; pdb_00006a4g; pdb_00006a4h; pdb_00006ai7; pdb_00006bfg; pdb_00006dvh; pdb_00006dvi; pdb_00006gmb; pdb_00006gmc; pdb_00006w44; pdb_00006w45; pdb_00006w4c; pdb_00007bsr; pdb_00007f1y; pdb_00007f20; pdb_00007f21; pdb_00007f22; pdb_00007m2o; pdb_00007r4n; pdb_00007r4o; pdb_00007r4p; pdb_00008ufy
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