PROSITE entry PS00557

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General information about the entry

Entry name [info]	FMN_HYDROXY_ACID_DH_1
Accession [info]	PS00557
Entry type [info]	PATTERN
Date [info]	01-DEC-1991 CREATED; 01-DEC-1991 DATA UPDATE; 13-SEP-2023 INFO UPDATE.
PROSITE Doc. [info]	PDOC00482
Associated ProRule [info]	PRU00683

Name and characterization of the entry

Description [info]	FMN-dependent alpha-hydroxy acid dehydrogenases active site.
Pattern [info]	S-N-H-G-[AG]-R-Q.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2023_04 which contains 570'157 sequence entries.

Total number of hits	153 in 153 different sequences
Number of true positive hits	153 in 153 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	8
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	95.03 %

Comments [info]

Taxonomic range [info]	Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Site [info]	active_site at position 3
Site [info]	substrate_binding at position 6
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

153 sequences

CYB2_WICAO  (P09437), CYB2_YEAST  (P00175), FUB9_FUSO4  (A0A0D2YG00),

FUB9_GIBF5  (S0DRI9), FUB9_GIBM7  (W7NCP1), GLO1_ARATH  (Q9LRR9), 
GLO1_ORYSI  (B8AKX6), GLO1_ORYSJ  (Q10CE4), GLO2_ARATH  (Q9LRS0), 
GLO2_ORYSI  (Q01KC2), GLO2_ORYSJ  (Q7XPR4), GLO3_ORYSI  (B8AUI3), 
GLO3_ORYSJ  (Q7FAS1), GLO5_ARATH  (O49506), GLO5_ORYSI  (B8B7C5), 
GLO5_ORYSJ  (Q6YT73), GOX1_MAIZE  (A0A3L6E0R4), GOX_SPIOL   (P05414), 
HAOX1_ARATH (Q9LJH5), HAOX1_HUMAN (Q9UJM8), HAOX1_MOUSE (Q9WU19), 
HAOX1_RAT   (B0BNF9), HAOX2_ARATH (Q24JJ8), HAOX2_BOVIN (Q3ZBW2), 
HAOX2_HUMAN (Q9NYQ3), HAOX2_MOUSE (Q9NYQ2), HAOX2_RAT   (Q07523), 
HAOX_DICDI  (Q54E41), HAOX_ORYSI  (B8B8K5), HAOX_ORYSJ  (Q8H3I4), 
HMO_AMYOR   (O52792), LLDD_ACIAD  (Q6FFS1), LLDD_ACIB3  (B7H2H0), 
LLDD_ACIB5  (B7IBS4), LLDD_ACIBC  (B2I061), LLDD_ACIBS  (B0VND0), 
LLDD_ACIBT  (A3M0X0), LLDD_ACIBY  (B0V6L1), LLDD_ACTP2  (A3N3E5), 
LLDD_ACTP7  (B3GZA5), LLDD_ACTPJ  (B0BTC7), LLDD_ALCFA  (Q6WB83), 
LLDD_ALLAM  (B9K115), LLDD_AZOC5  (A8HTC9), LLDD_BARHE  (Q6G4R2), 
LLDD_BARQU  (Q6G0J2), LLDD_BART1  (A9IN89), LLDD_CAUSK  (B0T7X2), 
LLDD_CAUVC  (Q9A943), LLDD_CAUVN  (B8H3Q5), LLDD_CHRSD  (Q1R0J2), 
LLDD_CITK8  (A8ARJ1), LLDD_CROS8  (A7MNF6), LLDD_ECO24  (A7ZTF9), 
LLDD_ECO27  (B7ULG1), LLDD_ECO45  (B7MFG9), LLDD_ECO55  (B7L725), 
LLDD_ECO57  (Q8XDF7), LLDD_ECO5E  (B5YWA7), LLDD_ECO7I  (B7NPB4), 
LLDD_ECO81  (B7N251), LLDD_ECO8A  (B7M492), LLDD_ECOBW  (C4ZXJ7), 
LLDD_ECODH  (B1X8M0), LLDD_ECOHS  (A8A670), LLDD_ECOK1  (A1AHE2), 
LLDD_ECOL5  (Q0TBK1), LLDD_ECOL6  (Q8FCB1), LLDD_ECOLC  (B1IZI5), 
LLDD_ECOLI  (P33232), LLDD_ECOLU  (B7NER0), LLDD_ECOSE  (B6I3I4), 
LLDD_ECOSM  (B1LK44), LLDD_ECOUT  (Q1R4Z0), LLDD_ENT38  (A4W540), 
LLDD_ESCF3  (B7LTL2), LLDD_HAEDU  (Q7VPI9), LLDD_HAEI8  (Q4QJK8), 
LLDD_HAEIE  (A5UBE3), LLDD_HAEIG  (A5UFG9), LLDD_HAEIN  (P46454), 
LLDD_KLEP3  (B5XMV0), LLDD_KLEP7  (A6TFK0), LLDD_MYCTO  (P9WND4), 
LLDD_MYCTU  (P9WND5), LLDD_PECAS  (Q6DAY3), LLDD_PSEA7  (A6VCM8), 
LLDD_PSEA8  (B7V1I3), LLDD_PSEAB  (Q02FQ1), LLDD_PSEAE  (Q9HV37), 
LLDD_PSEE4  (Q1IF69), LLDD_PSEFS  (C3K053), LLDD_PSEMY  (A4XYG7), 
LLDD_PSEP1  (A5W9B2), LLDD_PSEPG  (B0KIT4), LLDD_PSEPK  (Q88DT3), 
LLDD_PSEPW  (B1J244), LLDD_PSEU2  (Q4ZY06), LLDD_SALA4  (B5EXA8), 
LLDD_SALAR  (A9MLC3), LLDD_SALCH  (Q57ID8), LLDD_SALDC  (B5FLH2), 
LLDD_SALEP  (B5R5C7), LLDD_SALG2  (B5RGI4), LLDD_SALHS  (B4T986), 
LLDD_SALNS  (B4SXA4), LLDD_SALPA  (Q5PLQ7), LLDD_SALPB  (A9MVJ5), 
LLDD_SALPC  (C0Q1T7), LLDD_SALPK  (B5BHX7), LLDD_SALSV  (B4TZU7), 
LLDD_SALTI  (Q8Z2E5), LLDD_SALTY  (Q8ZL61), LLDD_SERP5  (A8GIL1), 
LLDD_SHIB3  (B2U5C2), LLDD_SHIBS  (Q31V17), LLDD_SHIDS  (Q329P9), 
LLDD_SHIF8  (Q0SYD1), LLDD_SHIFL  (Q83PP7), LLDD_SHISS  (Q3YVX0), 
LLDD_STRM5  (B4SMK1), LLDD_STRMK  (B2FIJ0), LLDD_VIBCH  (Q9KKW6), 
LLDD_VIBCM  (C3LWP7), LLDD_VIBPA  (Q87G18), LLDD_XANAC  (Q8PR33), 
LLDD_XANC5  (Q3BZH2), LLDD_XANC8  (Q4V0H2), LLDD_XANCB  (B0RLM2), 
LLDD_XANCP  (Q8PE75), LLDD_XANOM  (Q2P9K0), LLDD_XANOP  (B2SUY3), 
LLDD_XANOR  (Q5H6Z4), LLDD_XANP2  (A7IMB0), LLDD_YERP3  (A7FJF0), 
LLDD_YERPA  (Q1C9P0), LLDD_YERPB  (B2JZQ1), LLDD_YERPE  (Q8ZFV8), 
LLDD_YERPG  (A9R623), LLDD_YERPN  (Q1CGZ1), LLDD_YERPP  (A4TKI4), 
LLDD_YERPS  (Q66C32), LLDD_YERPY  (B1JPU0), LMO_MYCSM   (P21795), 
LOX_AERVM   (Q44467), LOX_CHLRE   (F8WQN2), LOX_LACRM   (C2K1F0), 
LOX_LENH9   (C0XIJ3), LOX_LYSSC   (B1HZY7), LOX_NOSS1   (Q8Z0C8), 
MDLB_PSEPU  (P20932), QULF_PENCI  (P0DUR7), YKN3_SCHPO  (Q9HDX2)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

8 sequences

CYB2_TALSN  (B8MKR3), CYBL_RHOGR  (P32953), LOX_ALIDK   (F4G5A4),

LOX_LACJE   (A0A5N1I561), LOX_ROSS0   (B7RR92), LOX_STRIN   (O33655), 
MFTD_MYCTO  (P9WND6), MFTD_MYCTU  (P9WND7)

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PDB
[Detailed view]

100 PDB

1AL7; 1AL8; 1FCB; 1GOX; 1GYL; 1HUV; 1KBI; 1KBJ; 1LCO; 1LDC; 1LTD; 1P4C; 1P5B; 1QCW; 1SZE; 1SZF; 1SZG; 1TB3; 2A7N; 2A7P; 2A85; 2DU2; 2E77; 2J6X; 2NLI; 2NZL; 2RDT; 2RDU; 2RDW; 2W0U; 2ZFA; 3GIY; 3SGZ; 4RJE; 4YL2; 5EBU; 5QIB; 5QIC; 5QID; 5QIE; 5QIF; 5QIG; 5QIH; 5ZZP; 5ZZQ; 5ZZR; 5ZZS; 5ZZT; 5ZZX; 5ZZY; 5ZZZ; 6A00; 6A01; 6A08; 6A0B; 6A0D; 6A0G; 6A0M; 6A0O; 6A0V; 6A0Y; 6A11; 6A13; 6A19; 6A1A; 6A1B; 6A1H; 6A1L; 6A1M; 6A1N; 6A1P; 6A1R; 6A1W; 6A21; 6A23; 6A24; 6A36; 6A39; 6A3D; 6A3T; 6A4G; 6A4H; 6AI7; 6BFG; 6DVH; 6DVI; 6GMB; 6GMC; 6W44; 6W45; 6W4C; 7BSR; 7F1Y; 7F20; 7F21; 7F22; 7M2O; 7R4N; 7R4O; 7R4P
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