General rule information
[?]
Accession |
PRU00683 |
Dates |
17-JAN-2008 (Created) 21-NOV-2019 (Last updated, Version 7) |
Predictors |
PROSITE; PS51349; FMN_HYDROXY_ACID_DH_2
|
Name |
FMN-dependent alpha-hydroxy acid dehydrogenase domain |
Function |
These enzymes are oxidoreductases that act on alpha-hydroxy acids and which are FMN-containing flavoproteins with a TIM barrel structure. |
Propagated annotation
[?]
case <Feature:PS51349:278=H>
end case
Cofactor |
FMN |
Similarity |
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. |
case <Feature:PS51349:278=H>
PROSITE |
PS00557; FMN_HYDROXY_ACID_DH_1; 1; |
GO:0016491; Molecular function: oxidoreductase activity.
end case
case <Feature:PS51349:278=H>
end case
From: PS51349 |
Key
|
|
From
|
|
To
|
|
Description
|
|
Tag
|
|
Condition
|
|
FTGroup
|
DOMAIN
|
|
from
|
|
to
|
|
FMN hydroxy acid dehydrogenase #
|
|
|
|
|
|
|
NP_BIND
|
|
309
|
|
333
|
|
FMN
|
|
|
|
|
|
|
ACT_SITE
|
|
278
|
|
278
|
|
Proton acceptor
|
|
|
|
H
|
|
|
BINDING
|
|
27
|
|
27
|
|
Substrate
|
|
|
|
Y
|
|
|
BINDING
|
|
109
|
|
109
|
|
FMN
|
|
|
|
S
|
|
|
BINDING
|
|
131
|
|
131
|
|
FMN
|
|
|
|
Q
|
|
|
BINDING
|
|
133
|
|
133
|
|
Substrate
|
|
|
|
Y
|
|
|
BINDING
|
|
159
|
|
159
|
|
FMN
|
|
|
|
T
|
|
|
BINDING
|
|
168
|
|
168
|
|
Substrate
|
|
|
|
R
|
|
|
BINDING
|
|
254
|
|
254
|
|
FMN
|
|
|
|
K
|
|
|
BINDING
|
|
281
|
|
281
|
|
Substrate
|
|
|
|
R
|
|
|
Additional information
[?]
Size range |
340-390 amino acids |
Related rules |
None |
Repeats |
1 |
Topology |
Undefined |
Example |
Q6FFS1 (LLDD_ACIAD) |
Scope |
Eukaryota
Bacteria |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and
distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives
(CC BY-NC-ND 4.0) License, see
prosite_license.html.
UniProtKB rule member sequences
[?]