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PROSITE entry PS00591


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00591
Entry name [info] GH10_1
Accession [info] PS00591
Entry type [info] PATTERN
Date [info] 01-DEC-1991 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00510
Associated ProRule [info] PRU10061

Name and characterization of the entry

Description [info] Glycosyl hydrolases family 10 (GH10) active site.
Pattern [info] 
[GTA]-{QNAG}-{GSV}-[LIVN]-x-[IVMF]-[ST]-E-[LIY]-[DN]-[LIVMF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 82 in 82 different sequences
Number of true positive hits 50 in 50 different sequences
Number of 'unknown' hits 1
Number of false positive hits 31 in 31 different sequences
Number of false negative sequences 20
Number of 'partial' sequences 4
Precision (true positives / (true positives + false positives)) 61.73 %
Recall (true positives / (true positives + false negatives)) 71.43 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 8
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 50 sequences 

CEXY_THEST  (P40942), GUNB_CALSA  (P10474), GUNF_FUSOX  (P46239), 

GUX_CELFI   (P07986), XLNA_AGABI  (O60206), XY10C_CELJA (Q59675), 
XYN1_ARATH  (A0A1P8AWH8), XYN1_GEOSE  (P40943), XYN1_PENPR  (A0A2U7QU15), 
XYN1_RHIOR  (W0HFK8), XYN2_ARATH  (O80596), XYN2_CLAPU  (O74717), 
XYN2_GEOSE  (P45703), XYN3_ARATH  (F4JG10), XYN4_CALSA  (P23557), 
XYNA1_PAESJ (C6CRV0), XYNA_ASPAC  (O59859), XYNA_ASPKW  (P33559), 
XYNA_BACOV  (P49942), XYNA_BUTFI  (P23551), XYNA_CALSA  (P23556), 
XYNA_CALSR  (P40944), XYNA_CELJU  (P14768), XYNA_HALH5  (P07528), 
XYNA_NAGAL  (P07529), XYNA_PENCH  (P29417), XYNA_PENCN  (Q5S7A8), 
XYNA_PENSI  (P56588), XYNA_PHACH  (Q9HEZ1), XYNA_RUMFL  (P29126), 
XYNA_STRLI  (P26514), XYNA_TALPU  (Q9P8J1), XYNA_THEAU  (P23360), 
XYNA_THEMA  (Q60037), XYNA_THENE  (Q60042), XYNA_THESA  (P36917), 
XYNA_XYLRU  (P48789), XYNB_BUTFI  (P26223), XYNB_CELJU  (P23030), 
XYNB_NEOPA  (Q02290), XYNC_ASPNC  (A2QFV7), XYNC_ASPNG  (C5J411), 
XYNC_PAEBA  (O69230), XYNC_PHACH  (B7SIW2), XYND_TALFU  (Q5ZNB1), 
XYNF1_ASPFN (B8NER4), XYNX_ACETH  (P38535), XYNY_ACETH  (P51584), 
XYNZ_ACET2  (P10478), XYN_PENCH   (Q6PRW6)
» more

UniProtKB/Swiss-Prot
False negative sequences		 20 sequences 

XYFA_XYLR2  (D5EY13), XYN4_ARATH  (Q680B7), XYN5L_ARATH (Q84WT5), 

XYN5_ARATH  (A0A1P8B8F8), XYNA_DICTH  (Q12603), XYNA_HUMIN  (M4MGK7), 
XYNB_HUMIN  (M4MLB5), XYNB_PAEBA  (O69231), XYNB_THENE  (Q60041), 
XYNC_ASPCL  (A1CHQ0), XYNC_ASPFC  (B0Y6E0), XYNC_ASPFU  (Q0H904), 
XYNC_ASPTE  (Q4JHP5), XYNC_ASPTN  (Q0CBM8), XYNC_EMENI  (Q00177), 
XYNC_HUMIN  (M4MEY9), XYNC_NEOFI  (A1CX14), XYNF1_ASPOR (O94163), 
XYNF3_ASPFN (B8NXJ2), XYNF3_ASPOR (Q96VB6)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 4 sequences 

XYNA_DICB4  (P80718), XYNA_FUSO4  (B3A0S5), XYNA_GLOTR  (P84195), 

XYNB_DICB4  (P80717)
» more

UniProtKB/Swiss-Prot
'Unknown' sequences		 1 sequence 

L_LASV  (Q6GWS6)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			31 sequences
			


			
BAHL1_ORYSI (A2XK56), BAHL1_ORYSJ (Q7XZZ3), CBIT_METTH  (O26249), 

			
CHLB_CHLAT  (Q19V92), CSMD1_HUMAN (Q96PZ7), CSMD2_HUMAN (Q7Z408), 
CSMD3_HUMAN (Q7Z407), CSMD3_MOUSE (Q80T79), DCA12_CHICK (Q5F3R7), 
DIVIB_MACCJ (B9EB52), ENGB_METMP  (Q6LXQ9), ERG29_YEAST (P40207), 
EZRA_BACSU  (O34894), FBL66_ARATH (Q9LX48), FHY3_ARATH  (Q9LIE5), 
KCTD6_DANRE (Q6DG99), P4_PCVC (Q8JVB9), PRS39_MOUSE (O70169), 
PTR1_SCHPO  (O13834), RL24_NATPD  (Q3IMX7), RL25_STAA3  (Q2FJE0), 
RL25_STAAB  (Q2YVY4), RL25_STAAC  (Q5HIH4), RL25_STAAM  (Q99WA2), 
RL25_STAAN  (Q7A7B3), RL25_STAAR  (Q6GJH0), RL25_STAAS  (Q6GBY7), 
RL25_STAAW  (Q7A1S4), URC2_LACKL  (Q6YFE6), URC2_YEAST  (Q04411), 
Y015_SIFVH  (Q914L5)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			71 PDB
			


			1B30; 1B31; 1B3V; 1B3W; 1B3X; 1B3Y; 1B3Z; 1BG4; 1CLX; 1E0V; 1E0W; 1E0X; 
			
				1EXP; 1FH7; 1FH8; 1FH9; 1FHD; 1GOK; 1GOM; 1GOO; 1GOQ; 1GOR; 1HIZ; 1I1W; 
				1I1X; 1J01; 1K6A; 1OD8; 1R85; 1R87; 1TUX; 1US2; 1US3; 1V0K; 1V0L; 1V0M; 
				1V0N; 1W2P; 1W2V; 1W32; 1W3H; 1XAS; 1XYZ; 2BNJ; 2DEP; 2EXO; 2HIS; 2UWF; 
				2W5F; 2WYS; 2WZE; 2XYL; 3CUF; 3CUG; 3CUH; 3CUI; 3CUJ; 3MMD; 3O2L; 3RDK; 
				3RO8; 4E4P; 4PRW; 4PUD; 4PUE; 4W8L; 4XUY; 7CPK; 7CPL; 8XY0; 8Y1M
			
			

			» more