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PROSITE entry PS00602


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00602
Entry name [info] ALDOLASE_CLASS_II_1
Accession [info] PS00602
Entry type [info] PATTERN
Date [info] 01-DEC-1991 CREATED;
01-DEC-2001 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00523

Name and characterization of the entry

Description [info] Fructose-bisphosphate aldolase class-II signature 1.
Pattern [info] 
[FYVMT]-x(1,3)-[LIVMH]-[APNT]-[LIVM]-x(1,2)-[LIVM]-H-x-D-H-[GACH].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 116 in 115 different sequences
Number of true positive hits 113 in 112 different sequences
Number of 'unknown' hits 0
Number of false positive hits 3 in 3 different sequences
Number of false negative sequences 24
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 97.41 %
Recall (true positives / (true positives + false negatives)) 82.48 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 112 sequences 

ALF1_CERSP  (P27995), ALF1_CUPNH  (Q59100), ALF1_PARBA  (Q96UH7), 

ALF2_CERSP  (P29271), ALF2_CUPNH  (Q59101), ALF2_PARBA  (Q8J0N6), 
ALF2_SYNY3  (Q55664), ALF_ASPOR   (Q9HGY9), ALF_BACSU   (P13243), 
ALF_BORBU   (O51401), ALF_BUCAI   (P57526), ALF_BUCAP   (Q8K9B2), 
ALF_BUCBP   (Q89AB6), ALF_CAMJE   (Q0PAS0), ALF_CAMJJ   (A1VYV7), 
ALF_CANAL   (Q9URB4), ALF_CORGL   (P19537), ALF_ECO57   (P0AB72), 
ALF_ECOLI   (P0AB71), ALF_EDWI9   (O52402), ALF_GEOSE   (P94453), 
ALF_HAEIN   (P44429), ALF_HELPJ   (Q9ZMQ6), ALF_HELPY   (P56109), 
ALF_KLULA   (Q9C2U0), ALF_MYCBO   (P67476), ALF_MYCGE   (P47269), 
ALF_MYCLE   (O69600), ALF_MYCTO   (P9WQA2), ALF_MYCTU   (P9WQA3), 
ALF_NEUCR   (P53444), ALF_NOSCO   (Q9XDP3), ALF_NOSS1   (Q8YNK2), 
ALF_PSEAE   (Q9I5Y1), ALF_RHIME   (P58336), ALF_SCHPO   (P36580), 
ALF_SHIFL   (P0AB73), ALF_SINMW   (P56888), ALF_STRCO   (Q9X8R6), 
ALF_STRGB   (Q9ZEM7), ALF_STRP1   (P68905), ALF_STRP3   (P0CZ58), 
ALF_STRP6   (Q5XA12), ALF_STRP8   (P68906), ALF_STRPN   (P0A4S1), 
ALF_STRPQ   (P0CZ59), ALF_STRR6   (P0A4S2), ALF_STUST   (O87796), 
ALF_TREPA   (O83668), ALF_XANFL   (Q56815), ALF_YEAST   (P14540), 
GATY_ECO24  (A7ZNR5), GATY_ECO27  (B7UFB3), GATY_ECO45  (B7MEF1), 
GATY_ECO55  (B7L9W7), GATY_ECO57  (Q8X4R2), GATY_ECO5E  (B5YV43), 
GATY_ECO7I  (B7NPN7), GATY_ECO8A  (B7M477), GATY_ECOBW  (C4ZSI0), 
GATY_ECODH  (B1X7I7), GATY_ECOHS  (A8A1W1), GATY_ECOK1  (A1ACW2), 
GATY_ECOL5  (Q0TFZ6), GATY_ECOL6  (Q8FFY7), GATY_ECOLC  (B1IYY4), 
GATY_ECOLI  (P0C8J6), GATY_ECOLU  (B7NCC6), GATY_ECOLX  (P0C8J7), 
GATY_ECOSM  (B1LN92), GATY_ECOUT  (Q1R9X7), GATY_SALPA  (Q5PL86), 
GATY_SALPB  (A9N6Z8), GATY_SALPK  (B5BGG5), GATY_SALTI  (Q8XGZ9), 
GATY_SALTY  (Q7CPQ7), GATY_SHIB3  (B2TY92), GATY_SHIBS  (Q323C6), 
GATY_SHIF8  (Q0T342), GATY_SHIFL  (Q83QY5), GATY_SHISS  (Q3Z0B4), 
IOLJ_BACLD  (Q65D09), IOLJ_BACSU  (P42420), IOLJ_BACVZ  (A7ZAH2), 
IOLJ_HALH5  (Q9KAH3), KBAY_CITK8  (A8AQ28), KBAY_ECO24  (A7ZS33), 
KBAY_ECO27  (B7UJ37), KBAY_ECO45  (B7MB62), KBAY_ECO55  (B7LH72), 
KBAY_ECO57  (P0AB76), KBAY_ECO5E  (B5YS30), KBAY_ECO7I  (B7NKL0), 
KBAY_ECO81  (B7N0S6), KBAY_ECO8A  (B7M045), KBAY_ECOBW  (C4ZR47), 
KBAY_ECODH  (B1XGU9), KBAY_ECOHS  (A8A4V3), KBAY_ECOK1  (A1AG46), 
KBAY_ECOL5  (Q0TCW8), KBAY_ECOL6  (P0AB75), KBAY_ECOLC  (B1IRH9), 
KBAY_ECOLI  (P0AB74), KBAY_ECOLU  (B7NDC5), KBAY_ECOLX  (Q9KIP8), 
KBAY_ECOSE  (B6I1L2), KBAY_ECOSM  (B1LFP2), KBAY_ECOUT  (Q1R6K0), 
KBAY_ENT38  (A4WEV6), KBAY_ESCF3  (B7LMU4), KBAY_SALAR  (A9MPP7), 
SQIA_ALKUR  (A0A2P6MHY1)
» more

UniProtKB/Swiss-Prot
False negative sequences		 24 sequences 

ALF2_STAAC  (Q5HE75), ALF2_STAAM  (P67477), ALF2_STAAN  (P99075), 

ALF2_STAAR  (Q6GEV0), ALF2_STAAS  (Q6G7I5), ALF2_STAAW  (P67478), 
ALF2_STAEQ  (Q5HM97), ALF2_STAES  (Q8CNI3), ALF_COCIM   (P0CJ44), 
ALF_HALVD   (D4GYE0), ALF_MYCPN   (P75089), ALF_THECA   (Q703I2), 
ALF_UREPA   (Q9PPP3), GATY_KLEOX  (Q8VS16), GATY_KLEP7  (A6TEF4), 
GATY_SALCH  (Q57JK9), GATY_SALEP  (B5QZS8), GATY_SALG2  (B5REK6), 
GATY_SALHS  (B4TIX9), GATY_SALNS  (B4T6B9), GATY_SALPC  (C0PZ24), 
GATY_SALSV  (B4TWB0), GATY_SHIDS  (Q32EA9), IOLJ_SHOC1  (Q5WKY5)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 2 sequences 

ALF2_RHOCA  (P50923), ALF_ANASL   (P83155)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			3 sequences
			


			
BANP_XENLA  (Q5FWL0), CISY_DEIRA  (Q9RWB2), CISY_HALVD  (D4GS06)


				
	

	

		PDB
[Detailed view]		
		
			40 PDB
			


			1B57; 1DOS; 1GVF; 1GYN; 1ZEN; 3C4U; 3C52; 3C56; 3EKL; 3EKZ; 3ELF; 3QM3; 
			
				4A21; 4A22; 4DEF; 4DEL; 4LV4; 5GK3; 5GK4; 5GK5; 5GK6; 5GK7; 5GK8; 5UCK; 
				5UCN; 5UCP; 5UCS; 5UCZ; 5UD0; 5UD1; 5UD2; 5UD3; 5UD4; 5VJD; 5VJE; 5VJF; 
				6LNK; 7V6F; 7V6G; 7YVA
			
			

			» more