PROSITE entry PS00705

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS00705
Entry name [info]	PROK_CO2_ANHYDRASE_2
Accession [info]	PS00705
Entry type [info]	PATTERN
Date [info]	01-DEC-1992 CREATED; 01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00586

Name and characterization of the entry

Description [info]	Prokaryotic-type carbonic anhydrases signature 2.
Pattern [info]	[EQ]-[YF]-A-[LIVM]-x(2)-[LIVM]-x(4)-[LIVMF](3)-x-G-H-x(2)-C-G.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	28 in 28 different sequences
Number of true positive hits	28 in 28 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	7
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	80.00 %

Comments [info]

Taxonomic range [info]	Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

28 sequences

BCA1_ARATH  (P27140), BCA2_ARATH  (P42737), BCA4_ARATH  (Q94CE4),

BCA6_ARATH  (Q9C6F5), CAH1_FLALI  (P46512), CAH2_FLALI  (P46513), 
CAHC_HORVU  (P40880), CAHC_PEA(P17067), CAHC_SPIOL  (P16016), 
CAHC_TOBAC  (P27141), CAHX_FLABI  (P46510), CAHX_FLABR  (P46511), 
CAHX_FLAPR  (P46281), CAN_CANAL   (Q5AJ71), CAN_ECOLI   (P61517), 
CAN_HAEIN   (P45148), CAN_SHIFL   (P61518), CAN_YEAST   (P53615), 
CYNT_ECO57  (P0ABF0), CYNT_ECOLI  (P0ABE9), CYNT_HELPJ  (Q9ZN54), 
CYNT_HELPY  (O24855), CYNT_MYCS2  (A0R566), CYNT_PSEAE  (Q9I262), 
CYNT_SYNE7  (P27134), CYNT_SYNY3  (Q54735), MTCA2_MYCTO (P9WPJ8), 
MTCA2_MYCTU (P9WPJ9)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

7 sequences

BCA1_CAEBR  (A8XKV0), BCA1_CAEEL  (Q22460), BCA3_ARATH  (Q9ZUC2),

BCA5_ARATH  (Q94CE3), CAN_EMENI   (Q5BCC5), YTIB_BACSU  (O34872), 
YVDA_BACSU  (O06983)

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PDB
[Detailed view]

31 PDB

1EKJ; 1I6O; 1I6P; 1T75; 1YM3; 2A5V; 2A8C; 2A8D; 2ESF; 3E1V; 3E1W; 3E24; 3E28; 3E2A; 3E2W; 3E2X; 3E31; 3E3F; 3E3G; 3E3I; 3EYX; 3MF3; 4WAJ; 4WAK; 4WAM; 5SWC; 6GWU; 7SEV; 9EAT; 9EAW; 9EBZ
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