PROSITE entry PS00777

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PURL: https://purl.expasy.org/prosite/signature/PS00777

Direct ScanProsite submission

General information about the entry

Entry name [info]	GH11_2
Accession [info]	PS00777
Entry type [info]	PATTERN
Date [info]	01-DEC-1992 CREATED; 01-NOV-1995 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00622
Associated ProRule [info]	PRU10063

Name and characterization of the entry

Description [info]	Glycosyl hydrolases family 11 (GH11) active site signature 2.
Pattern [info]	[LIVMF]-x(2)-E-[AG]-[YWG]-[QRFGS]-[SG]-[STAN]-G-x-[SAF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.

Total number of hits	81 in 80 different sequences
Number of true positive hits	75 in 74 different sequences
Number of 'unknown' hits	0
Number of false positive hits	6 in 6 different sequences
Number of false negative sequences	13
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	92.59 %
Recall (true positives / (true positives + false negatives))	85.23 %

Comments [info]

Taxonomic range [info]	Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	2
Site [info]	active_site at position 3
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	74 sequences EIX1_BOTFB (A0A384JXV5), EIX3_VERDV (G2X8M4), EIX3_VERLO (A0A0G4KL96), EIX5_VERDV (G2X4G1), EIX_HYPRU (Q9UVF9), EIX_PEND1 (K9GHZ3), XY11A_BOTFB (B3VSG7), XY11A_BOTFU (Q2LMP0), XY11A_HUMIN (V9TS54), XY11A_PSEXY (P83513), XY11B_HUMIN (A0A0B5JC15), XYN11_PAEBA (V9TXH2), XYN1B_HUMIN (P55334), XYN1_COCCA (Q06562), XYN1_HYPJQ (G0R947), XYN1_HYPJR (P36218), XYN1_LEUGO (A6YAP7), XYN1_PYRGI (P0CT48), XYN1_PYRO7 (P0CT49), XYN2_HUMIN (Q9HGE1), XYN2_HYPJQ (G0RUP7), XYN2_HYPJR (P36217), XYN2_RHIOR (W0HJ53), XYN2_TRIHA (B5A7N4), XYN3_ASPKW (P33557), XYN3_PENPR (A0A2U7R6V5), XYN4_PYRGI (Q92245), XYN4_PYRO7 (G4NA54), XYN6_ASPNG (Q6QJ75), XYNA1_THEST (Q8GJ44), XYNA2_THEST (P33558), XYNA_ASPAW (P55328), XYNA_ASPCL (A1CCU0), XYNA_ASPFC (B0XXF3), XYNA_ASPFN (B8NKE9), XYNA_ASPFU (Q4WG11), XYNA_ASPNG (P55329), XYNA_ASPOR (Q9HFA4), XYNA_ASPTN (Q0CFS3), XYNA_ASPTU (P55331), XYNA_BACPU (P00694), XYNA_BACSU (P18429), XYNA_BYSSP (P81536), XYNA_CLOSA (P17137), XYNA_EMENI (P55332), XYNA_GEOSE (P45705), XYNA_GIBZE (I1S2K3), XYNA_NEOFI (A1DJ52), XYNA_NEOPA (P29127), XYNA_NIACI (P09850), XYNA_RUMFL (P29126), XYNA_SCHCO (P35809), XYNA_THELA (O43097), XYNB_ASPFC (B0Y8Q8), XYNB_ASPFU (Q4WLV2), XYNB_ASPKW (P48824), XYNB_ASPNC (A2Q7I0), XYNB_ASPNG (P55330), XYNB_EMENI (P55333), XYNB_GIBZE (I1RII8), XYNB_NEOFI (A1DNU5), XYNB_PENOX (E7EF85), XYNB_PHACH (B7SIW1), XYNB_STRLI (P26515), XYNB_STRSQ (D7EZJ3), XYNB_TALPU (Q96W72), XYNC_FIBSS (P35811), XYNC_STRCO (Q9RI72), XYNC_STRLI (P26220), XYND_CELFI (P54865), XYND_RUMFL (Q53317), XYNG_VERDA (Q0ZHI9), XYN_PHACE (O97402), XYN_TRIHA (P48793) » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	13 sequences EIX1_VERDV (G2X4G0), EIX2_BOTFB (A0A384K474), EIX2_VERDV (G2X0L1), EIX4_VERDV (G2X5X8), XY11A_CELJA (Q59674), XY11B_CELJA (Q8VP72), XYN4_ASPNG (Q12550), XYN5_ASPNC (A2R4D1), XYN5_ASPNG (Q12549), XYNA_PIRSP (Q12667), XYNB_ASPCL (A1CU59), XYNB_ASPFN (B8NJ86), XYNB_ASPOR (P87037) » more
UniProtKB/Swiss-Prot False positive sequences	6 sequences CHI1_RHINI (P29025), IF2_SYNY3 (P72689), PKHH3_HUMAN (Q7Z736), RPOA_RUBXD (Q1AU56), TETR1_ECOLX (P03038), TGAL8_ORYSJ (Q69T21) » more
PDB [Detailed view]	88 PDB pdb_00001axk; pdb_00001bk1; pdb_00001bvv; pdb_00001c5h; pdb_00001c5i; pdb_00001enx; pdb_00001hv0; pdb_00001hv1; pdb_00001pvx; pdb_00001red; pdb_00001ree; pdb_00001ref; pdb_00001t6g; pdb_00001ukr; pdb_00001xnb; pdb_00001xnc; pdb_00001xnd; pdb_00001xxn; pdb_00001xyn; pdb_00001xyo; pdb_00001xyp; pdb_00001yna; pdb_00002b42; pdb_00002b45; pdb_00002b46; pdb_00002bvv; pdb_00002c1f; pdb_00002d97; pdb_00002d98; pdb_00002dcy; pdb_00002dcz; pdb_00002dfb; pdb_00002dfc; pdb_00002vg9; pdb_00003exu; pdb_00003hd8; pdb_00003lb9; pdb_00003lgr; pdb_00003ri8; pdb_00003ri9; pdb_00003vzk; pdb_00003vzl; pdb_00003vzn; pdb_00003vzo; pdb_00004hk9; pdb_00004hkl; pdb_00004hkw; pdb_00004s2d; pdb_00004s2f; pdb_00004s2g; pdb_00004s2h; pdb_00004xpv; pdb_00004xq4; pdb_00004xqd; pdb_00004xqw; pdb_00005ej3; pdb_00005k7p; pdb_00005k9y; pdb_00005zf3; pdb_00005zh0; pdb_00005zh9; pdb_00005zii; pdb_00005ziw; pdb_00005zkz; pdb_00005zo0; pdb_00006jxl; pdb_00006k9o; pdb_00006kvv; pdb_00006kw9; pdb_00006kwd; pdb_00006kwf; pdb_00006qe8; pdb_00007mgu; pdb_00007vug; pdb_00007vuh; pdb_00007vui; pdb_00007vuj; pdb_00007xn9; pdb_00007xna; pdb_00008keu; pdb_00008qxy; pdb_00008qxz; pdb_00008qy0; pdb_00008qy1; pdb_00008qy2; pdb_00008qy3; pdb_00008r85; pdb_00008r86 » more