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PROSITE entry PS00777


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PURL: https://purl.expasy.org/prosite/signature/PS00777

Direct ScanProsite submission
General information about the entry

Entry name [info] GH11_2
Accession [info] PS00777
Entry type [info] PATTERN
Date [info] 01-DEC-1992 CREATED;
01-NOV-1995 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00622
Associated ProRule [info] PRU10063

Name and characterization of the entry

Description [info] Glycosyl hydrolases family 11 (GH11) active site signature 2.
Pattern [info]
[LIVMF]-x(2)-E-[AG]-[YWG]-[QRFGS]-[SG]-[STAN]-G-x-[SAF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 81 in 80 different sequences
Number of true positive hits 75 in 74 different sequences
Number of 'unknown' hits 0
Number of false positive hits 6 in 6 different sequences
Number of false negative sequences 13
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 92.59 %
Recall (true positives / (true positives + false negatives)) 85.23 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Site [info] active_site at position 3
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
74 sequences

EIX1_BOTFB  (A0A384JXV5), EIX3_VERDV  (G2X8M4), EIX3_VERLO  (A0A0G4KL96), 
EIX5_VERDV  (G2X4G1), EIX_HYPRU   (Q9UVF9), EIX_PEND1   (K9GHZ3), 
XY11A_BOTFB (B3VSG7), XY11A_BOTFU (Q2LMP0), XY11A_HUMIN (V9TS54), 
XY11A_PSEXY (P83513), XY11B_HUMIN (A0A0B5JC15), XYN11_PAEBA (V9TXH2), 
XYN1B_HUMIN (P55334), XYN1_COCCA  (Q06562), XYN1_HYPJQ  (G0R947), 
XYN1_HYPJR  (P36218), XYN1_LEUGO  (A6YAP7), XYN1_PYRGI  (P0CT48), 
XYN1_PYRO7  (P0CT49), XYN2_HUMIN  (Q9HGE1), XYN2_HYPJQ  (G0RUP7), 
XYN2_HYPJR  (P36217), XYN2_RHIOR  (W0HJ53), XYN2_TRIHA  (B5A7N4), 
XYN3_ASPKW  (P33557), XYN3_PENPR  (A0A2U7R6V5), XYN4_PYRGI  (Q92245), 
XYN4_PYRO7  (G4NA54), XYN6_ASPNG  (Q6QJ75), XYNA1_THEST (Q8GJ44), 
XYNA2_THEST (P33558), XYNA_ASPAW  (P55328), XYNA_ASPCL  (A1CCU0), 
XYNA_ASPFC  (B0XXF3), XYNA_ASPFN  (B8NKE9), XYNA_ASPFU  (Q4WG11), 
XYNA_ASPNG  (P55329), XYNA_ASPOR  (Q9HFA4), XYNA_ASPTN  (Q0CFS3), 
XYNA_ASPTU  (P55331), XYNA_BACPU  (P00694), XYNA_BACSU  (P18429), 
XYNA_BYSSP  (P81536), XYNA_CLOSA  (P17137), XYNA_EMENI  (P55332), 
XYNA_GEOSE  (P45705), XYNA_GIBZE  (I1S2K3), XYNA_NEOFI  (A1DJ52), 
XYNA_NEOPA  (P29127), XYNA_NIACI  (P09850), XYNA_RUMFL  (P29126), 
XYNA_SCHCO  (P35809), XYNA_THELA  (O43097), XYNB_ASPFC  (B0Y8Q8), 
XYNB_ASPFU  (Q4WLV2), XYNB_ASPKW  (P48824), XYNB_ASPNC  (A2Q7I0), 
XYNB_ASPNG  (P55330), XYNB_EMENI  (P55333), XYNB_GIBZE  (I1RII8), 
XYNB_NEOFI  (A1DNU5), XYNB_PENOX  (E7EF85), XYNB_PHACH  (B7SIW1), 
XYNB_STRLI  (P26515), XYNB_STRSQ  (D7EZJ3), XYNB_TALPU  (Q96W72), 
XYNC_FIBSS  (P35811), XYNC_STRCO  (Q9RI72), XYNC_STRLI  (P26220), 
XYND_CELFI  (P54865), XYND_RUMFL  (Q53317), XYNG_VERDA  (Q0ZHI9), 
XYN_PHACE   (O97402), XYN_TRIHA   (P48793)
» more

UniProtKB/Swiss-Prot
False negative sequences
13 sequences

EIX1_VERDV  (G2X4G0), EIX2_BOTFB  (A0A384K474), EIX2_VERDV  (G2X0L1), 
EIX4_VERDV  (G2X5X8), XY11A_CELJA (Q59674), XY11B_CELJA (Q8VP72), 
XYN4_ASPNG  (Q12550), XYN5_ASPNC  (A2R4D1), XYN5_ASPNG  (Q12549), 
XYNA_PIRSP  (Q12667), XYNB_ASPCL  (A1CU59), XYNB_ASPFN  (B8NJ86), 
XYNB_ASPOR  (P87037)
» more

UniProtKB/Swiss-Prot
False positive sequences
6 sequences

CHI1_RHINI  (P29025), IF2_SYNY3   (P72689), PKHH3_HUMAN (Q7Z736), 
RPOA_RUBXD  (Q1AU56), TETR1_ECOLX (P03038), TGAL8_ORYSJ (Q69T21)
» more

PDB
[Detailed view]
88 PDB

1AXK; 1BK1; 1BVV; 1C5H; 1C5I; 1ENX; 1HV0; 1HV1; 1PVX; 1RED; 1REE; 1REF; 1T6G; 1UKR; 1XNB; 1XNC; 1XND; 1XXN; 1XYN; 1XYO; 1XYP; 1YNA; 2B42; 2B45; 2B46; 2BVV; 2C1F; 2D97; 2D98; 2DCY; 2DCZ; 2DFB; 2DFC; 2VG9; 3EXU; 3HD8; 3LB9; 3LGR; 3RI8; 3RI9; 3VZK; 3VZL; 3VZN; 3VZO; 4HK9; 4HKL; 4HKW; 4S2D; 4S2F; 4S2G; 4S2H; 4XPV; 4XQ4; 4XQD; 4XQW; 5EJ3; 5K7P; 5K9Y; 5ZF3; 5ZH0; 5ZH9; 5ZII; 5ZIW; 5ZKZ; 5ZO0; 6JXL; 6K9O; 6KVV; 6KW9; 6KWD; 6KWF; 6QE8; 7MGU; 7VUG; 7VUH; 7VUI; 7VUJ; 7XN9; 7XNA; 8KEU; 8QXY; 8QXZ; 8QY0; 8QY1; 8QY2; 8QY3; 8R85; 8R86
» more