PROSITE entry PS00813

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PURL: https://purl.expasy.org/prosite/signature/PS00813

Direct ScanProsite submission

General information about the entry

Entry name [info]	IF4E
Accession [info]	PS00813
Entry type [info]	PATTERN
Date [info]	01-OCT-1993 CREATED; 01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00641

Name and characterization of the entry

Description [info]	Eukaryotic initiation factor 4E signature.
Pattern [info]	[DE]-[IFYL]-x(2)-F-[KRL]-x(2)-[LIVM]-x-P-x-W-E-[DVA]-x(5)-G-G-[KR]-W.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.

Total number of hits	57 in 57 different sequences
Number of true positive hits	57 in 57 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	7
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	89.06 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

57 sequences

I4E1B_HUMAN (A6NMX2), I4E1B_MOUSE (Q3UTA9), IF4E1_ARAHY (K0P2S0),

IF4E1_ARATH (O23252), IF4E1_CAEEL (O45551), IF4E1_CITLA (C7SG33), 
IF4E1_CUCME (P0DXI0), IF4E1_CUCMM (P0DXI5), IF4E1_CUCZE (A7KWF8), 
IF4E1_HORVV (Q4QXS7), IF4E1_LACSA (A0A2J6L8Y7), IF4E1_MAIZE (O81481), 
IF4E1_ORYSJ (P48599), IF4E1_PEA   (Q0GRC4), IF4E1_PHAVU (V7BSD0), 
IF4E1_PRUDO (M1JJT8), IF4E1_SCHPO (P78954), IF4E1_SOYBN (C6ZJZ3), 
IF4E1_TOBAC (A0A075QQ08), IF4E1_WHEAT (P29557), IF4E2_ARATH (Q9C7P2), 
IF4E2_CAEEL (Q21693), IF4E2_HUMAN (O60573), IF4E2_MAIZE (O81482), 
IF4E2_MOUSE (Q8BMB3), IF4E2_ORYSJ (P48600), IF4E2_SCHPO (O74743), 
IF4E2_SOLLC (A0A3Q7FGP1), IF4E2_TOBAC (Q66UV4), IF4E2_WHEAT (Q03389), 
IF4E3_ARATH (Q9C7P6), IF4E3_CAEEL (O61955), IF4E3_ORYSJ (Q10NQ9), 
IF4E3_WHEAT (A3RCV9), IF4E4_ARATH (O04663), IF4E4_CAEEL (Q22888), 
IF4E5_ARATH (Q9FK59), IF4E5_CAEEL (P56570), IF4EA_DANRE (Q9DFS6), 
IF4EB_DANRE (Q9PW28), IF4E_APLCA  (O77210), IF4E_BOVIN  (Q9N0T5), 
IF4E_CANAL  (Q9P975), IF4E_CANGA  (Q9P974), IF4E_DROME  (P48598), 
IF4E_EREGS  (Q75AV8), IF4E_HUMAN  (P06730), IF4E_MOUSE  (P63073), 
IF4E_RABIT  (P29338), IF4E_RAT(P63074), IF4E_XENLA  (P48597), 
IF4E_YEAST  (P07260), IFI4E_ARAHY (A0A445AGS0), IFI4E_CAPAN (A0A1U8F5V2), 
IFI4E_PRUDO (M1J8U6), IFI4E_SOLLC (A0A3Q7I7R4), IFI4E_TOBAC (Q66WU1)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

7 sequences

I4E3A_XENLA (Q6GR08), I4E3B_XENLA (Q6NU27), IF4E3_DANRE (Q66HY7),

IF4E3_HUMAN (Q8N5X7), IF4E3_MOUSE (Q9DBB5), IF4E3_XENTR (Q28ET8), 
IF4E_DICDI  (Q55FE0)

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PDB
[Detailed view]

99 PDB

pdb_00001ap8; pdb_00001ej1; pdb_00001ej4; pdb_00001ejh; pdb_00001ipb; pdb_00001ipc; pdb_00001l8b; pdb_00001rf8; pdb_00001wkw; pdb_00002gpq; pdb_00002idr; pdb_00002idv; pdb_00002jgb; pdb_00002jgc; pdb_00002v8w; pdb_00002v8x; pdb_00002v8y; pdb_00002w97; pdb_00002wmc; pdb_00003am7; pdb_00003tf2; pdb_00003u7x; pdb_00004axg; pdb_00004aza; pdb_00004bea; pdb_00004dt6; pdb_00004dum; pdb_00004tpw; pdb_00004tqb; pdb_00004tqc; pdb_00004ue8; pdb_00004ue9; pdb_00004uea; pdb_00004ueb; pdb_00004uec; pdb_00004ued; pdb_00005abu; pdb_00005abv; pdb_00005abx; pdb_00005aby; pdb_00005bxv; pdb_00005ehc; pdb_00005ei3; pdb_00005eir; pdb_00005ekv; pdb_00005gw6; pdb_00005j5o; pdb_00005j5y; pdb_00005m7v; pdb_00005m7w; pdb_00005m7x; pdb_00005m7z; pdb_00005m80; pdb_00005m81; pdb_00005m83; pdb_00005m84; pdb_00005me5; pdb_00005me6; pdb_00005me7; pdb_00005nvk; pdb_00005nvl; pdb_00005nvm; pdb_00005nvn; pdb_00005osx; pdb_00005t46; pdb_00005t47; pdb_00005t48; pdb_00005xln; pdb_00005zjy; pdb_00005zjz; pdb_00005zk5; pdb_00005zk7; pdb_00005zk9; pdb_00005zml; pdb_00006fc1; pdb_00006fc2; pdb_00006fc3; pdb_00006gkj; pdb_00006gkk; pdb_00006gkl; pdb_00006u06; pdb_00006u09; pdb_00006ylr; pdb_00006ylt; pdb_00006ylv; pdb_00007d6y; pdb_00007d8b; pdb_00007ezw; pdb_00007f07; pdb_00007meu; pdb_00007xtp; pdb_00008qm4; pdb_00008qm5; pdb_00008qm6; pdb_00008qm7; pdb_00008qm8; pdb_00008qm9; pdb_00008sx4; pdb_00009don
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