PROSITE entry PS00869

View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission

General information about the entry

Entry name [info]	RENAL_DIPEPTIDASE_1
Accession [info]	PS00869
Entry type [info]	PATTERN
Date [info]	01-OCT-1993 CREATED; 01-NOV-1995 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00678
Associated ProRule [info]	PRU10073

Name and characterization of the entry

Description [info]	Renal dipeptidase active site.
Pattern [info]	[LIVM]-E-G-[GA]-x(2)-[LIVMF]-x(6)-L-x(3)-Y-x(2)-G-[LIVM]-R.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_04 which contains 571'864 sequence entries.

Total number of hits	20 in 20 different sequences
Number of true positive hits	20 in 20 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	12
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	62.50 %

Comments [info]

Taxonomic range [info]	Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Site [info]	active_site at position 2
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

20 sequences

DPEP1_BOVIN (Q3SZM7), DPEP1_COCP7 (C5PCZ0), DPEP1_COCPS (E9D269),

DPEP1_HUMAN (P16444), DPEP1_MOUSE (P31428), DPEP1_PIG   (P22412), 
DPEP1_RABIT (P31429), DPEP1_RAT   (P31430), DPEP1_SHEEP (P43477), 
DPEP2_COCP7 (C5PCN6), DPEP2_COCPS (E9CV02), DPEP2_HUMAN (Q9H4A9), 
DPEP2_MOUSE (Q8C255), DPEP2_RAT   (Q5M872), DPEP3_HUMAN (Q9H4B8), 
DPEP3_MACFA (Q4R7M2), DPEP3_MOUSE (Q9DA79), DPEP3_RAT   (Q5U2X4), 
YPQQ_KLEPN  (P27509), YPQR_ACICA  (P07783)

» more

Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

12 sequences

DPEH1_SCHPO (O14124), DPEH2_SCHPO (O59832), DPEP1_ARTBC (D4B2N2),

DPEP1_ARTGP (E5R2Q7), DPEP1_ARTOC (C5FK77), DPEP1_TRIVH (D4DEJ7), 
DPEP2_FUSV7 (C7ZIE1), DPEP2_TALSN (B8LWT1), DPEP2_UNCRE (C4JQN7), 
GLIJ_ASPFU  (Q4WMJ8), SIRJ_LEPMC  (Q6Q886), TCPJ_CLAP2  (M1VV65)

» more

PDB
[Detailed view]

4 PDB

1ITQ; 1ITU; 6VGO; 6VGR