PROSITE entry PS00987

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS00987
Entry name [info]	PTPS_1
Accession [info]	PS00987
Entry type [info]	PATTERN
Date [info]	01-JUN-1994 CREATED; 01-NOV-1997 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00759
Associated ProRule [info]	PRU10123

Name and characterization of the entry

Description [info]	6-pyruvoyl tetrahydropterin synthase signature 1.
Pattern [info]	C-N-N-x(2)-G-H-G-H-N-Y.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	6 in 6 different sequences
Number of true positive hits	6 in 6 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	1
Number of 'partial' sequences	1

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	85.71 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	1
Site [info]	active_site at position 1
Site [info]	magnesium at position 6
Site [info]	magnesium at position 8
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	6 sequences PTPS_CAEEL (O02058), PTPS_DROME (P48611), PTPS_HUMAN (Q03393), PTPS_MOUSE (Q9R1Z7), PTPS_POERE (Q90W95), PTPS_RAT(P27213) » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	1 sequence PTPS_PONAB (Q5REZ5)
UniProtKB/Swiss-Prot 'Partial' sequences	1 sequence PTPS_SALSA (P80081)
PDB [Detailed view]	5 PDB 1B66; 1B6Z; 1GTQ; 2G64; 3I2B