PROSITE entry PS01012

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS01012
Entry name [info]	FOLYLPOLYGLU_SYNT_2
Accession [info]	PS01012
Entry type [info]	PATTERN
Date [info]	01-JUN-1994 CREATED; 01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00773

Name and characterization of the entry

Description [info]	Folylpolyglutamate synthase signature 2.
Pattern [info]	[LIVMFY](2)-[EK]-x-G-[LIVM]-[GA]-G-x(2)-D-x-[GST]-x-[LIVM](2).

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	33 in 33 different sequences
Number of true positive hits	32 in 32 different sequences
Number of 'unknown' hits	0
Number of false positive hits	1
Number of false negative sequences	3
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	96.97 %
Recall (true positives / (true positives + false negatives))	91.43 %

Comments [info]

Taxonomic range [info]	Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	32 sequences DHFS_ARATH (F4JYE9), FOLCP_HALSA (Q9HS44), FOLC_BACSU (Q05865), FOLC_BOVIN (A6H751), FOLC_BUCAI (P57265), FOLC_BUCAP (Q8K9X3), FOLC_BUCBP (Q89AT2), FOLC_CAEEL (Q09509), FOLC_CRIGR (Q924L9), FOLC_ECOLI (P08192), FOLC_HAEIN (P43775), FOLC_HUMAN (Q05932), FOLC_MOUSE (P48760), FOLC_MYCTU (I6Y0R5), FOLC_YEAST (P36001), FOLD_YEAST (Q12676), FOLE_CANAX (Q9Y893), FOLE_NEUCR (O13492), FOLE_SCHPO (O74742), FOLE_YEAS1 (B3LJR0), FOLE_YEAS6 (B5VSC3), FOLE_YEAS7 (A6ZP80), FOLE_YEAS8 (C8ZGZ3), FOLE_YEASA (E7KIA3), FOLE_YEASB (E7Q9C7), FOLE_YEASL (E7KUJ4), FOLE_YEASO (E7NMM0), FOLE_YEAST (Q08645), FOLE_YEASZ (E7QKX4), FPGS2_ARATH (F4J2K2), FPGS3_ARATH (Q8W035), FPGS_LACCA (P15925) » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	3 sequences FOLCP_HALVD (D4GW05), FOLC_DICDI (Q54CY5), FPGS1_ARATH (F4K2A1)
UniProtKB/Swiss-Prot False positive sequences	1 sequence PEX10_THET4 (G2Q0E2)
PDB [Detailed view]	11 PDB 1FGS; 1JBV; 1JBW; 1W78; 1W7K; 2GC5; 2GC6; 2GCA; 2GCB; 2VOR; 2VOS