PROSITE entry PS01028

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS01028
Entry name [info]	DEHYDROQUINASE_I
Accession [info]	PS01028
Entry type [info]	PATTERN
Date [info]	01-JUN-1994 CREATED; 01-DEC-2001 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00788

Name and characterization of the entry

Description [info]	Dehydroquinase class I active site.
Pattern [info]	D-[LIVM]-[DE]-[LIVMN]-x(18,20)-[LIVM](2)-x-[SC]-[NHY]-H-[DN].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	114 in 114 different sequences
Number of true positive hits	114 in 114 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	135
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	45.78 %

Comments [info]

Taxonomic range [info]	Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Site [info]	active_site at position 10
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

114 sequences

3DHQ_ACIAD  (Q59087), ARO11_TALMQ (B6QWH9), ARO12_TALMQ (B6QCA7),

ARO1_AJECG  (C0NL63), ARO1_AJECH  (C6HCG7), ARO1_AJECN  (A6R8Q8), 
ARO1_AJEDR  (C5G8R4), ARO1_ARTOC  (C5FQ73), ARO1_ASPCL  (A1CP85), 
ARO1_ASPFC  (B0XRM8), ARO1_ASPFN  (B8N4Q9), ARO1_ASPFU  (Q4WS76), 
ARO1_ASPOR  (Q2UCP6), ARO1_ASPTN  (Q0D0F3), ARO1_BLAGS  (C5JKE6), 
ARO1_CANGA  (Q6FIV4), ARO1_COCP7  (C5PA86), ARO1_EMENI  (P07547), 
ARO1_EREGS  (Q74ZZ1), ARO1_FUSV7  (C7YZ74), ARO1_KLULA  (Q6CJC4), 
ARO1_KOMPG  (C4R4R8), ARO1_LACTC  (C5DN02), ARO1_NEOFI  (A1D244), 
ARO1_NEUCR  (Q8X071), ARO1_PARBA  (C1H8L1), ARO1_PARBD  (C1FYJ9), 
ARO1_PARBP  (C0S433), ARO1_PENRW  (B6HAA7), ARO1_PHANO  (Q0V3H0), 
ARO1_PNECA  (Q12659), ARO1_PODAN  (B2B223), ARO1_PYRO7  (A4RD09), 
ARO1_SCLS1  (A7F7H0), ARO1_SCLSC  (Q5XNP0), ARO1_SORMK  (D1ZA70), 
ARO1_TALSN  (B8M0U4), ARO1_UNCRE  (C4JYG6), ARO1_VERA1  (C9SE96), 
ARO1_YARLI  (Q6C1X5), ARO1_YEAS1  (B3LGE9), ARO1_YEAS2  (C7GIN5), 
ARO1_YEAS7  (A6ZY89), ARO1_YEAS8  (C8Z543), ARO1_YEAST  (P08566), 
ARO1_ZYGRC  (C5DVG6), AROD_ALKOO  (A8MJ87), AROD_AQUAE  (O66440), 
AROD_BACLD  (Q65M66), AROD_BACSU  (P35146), AROD_BACVZ  (A7Z2G6), 
AROD_CLOBB  (B2TQ57), AROD_CLOD6  (Q186A6), AROD_CLONN  (A0PYE7), 
AROD_DESPS  (Q6AIT8), AROD_ECO24  (A7ZMF8), AROD_ECO27  (B7US32), 
AROD_ECO45  (B7MAQ3), AROD_ECO55  (B7L5P5), AROD_ECO57  (Q8X5X7), 
AROD_ECO5E  (B5YPY0), AROD_ECO7I  (B7NTU3), AROD_ECO81  (B7MVG9), 
AROD_ECO8A  (B7M0P9), AROD_ECOBW  (C4ZYF5), AROD_ECODH  (B1XG01), 
AROD_ECOHS  (A8A0N9), AROD_ECOK1  (A1ABN0), AROD_ECOL5  (Q0THD6), 
AROD_ECOL6  (Q8FH42), AROD_ECOLC  (B1IQ63), AROD_ECOLI  (P05194), 
AROD_ECOLU  (B7N529), AROD_ECOSE  (B6IBD3), AROD_ECOSM  (B1LE43), 
AROD_ECOUT  (Q1RBA3), AROD_ENTFA  (P36923), AROD_HYDS0  (B4U701), 
AROD_KLEP3  (B5Y1W9), AROD_KLEP7  (A6T4L2), AROD_LISIN  (Q92EG6), 
AROD_LISMC  (C1L005), AROD_LISMF  (Q723F8), AROD_LISMH  (B8DCI1), 
AROD_LISMO  (Q8Y9N4), AROD_LISW6  (A0AFU8), AROD_META3  (A6UTA2), 
AROD_METJA  (Q58849), AROD_METM5  (A4FWC6), AROD_METM6  (A9A9R9), 
AROD_METM7  (A6VGY0), AROD_METMP  (Q6LXF7), AROD_METVS  (A6UQ39), 
AROD_PYRFU  (Q8U0A7), AROD_SALA4  (B5F7D7), AROD_SALCH  (Q57PS8), 
AROD_SALDC  (B5FJ82), AROD_SALEN  (Q9RN77), AROD_SALEP  (B5QVU3), 
AROD_SALG2  (B5RAU8), AROD_SALHS  (B4TGJ6), AROD_SALPA  (Q5PH79), 
AROD_SALPB  (A9N159), AROD_SALSV  (B4TUS2), AROD_SALTI  (P24670), 
AROD_SALTY  (P58687), AROD_SHIB3  (B2U2J7), AROD_SHIBS  (Q321F0), 
AROD_SHIDS  (Q32GE2), AROD_SHIDY  (O87007), AROD_SHIF8  (Q0T478), 
AROD_SHIFL  (Q83RA1), AROD_SHISS  (Q3Z247), AROD_THEYD  (B5YH80)

» more

Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

135 sequences

ARO11_LODEL (A5H2Q8), ARO12_LODEL (A5H2P4), ARO1_CANAL  (Q5AME2),

ARO1_CANDC  (B9WFG1), ARO1_CANTT  (C5M1X2), ARO1_CLAL4  (C4Y9D5), 
ARO1_COPC7  (A8NMB4), ARO1_CRYNB  (P0CM23), ARO1_CRYNJ  (P0CM22), 
ARO1_LACBS  (B0D6H2), ARO1_MALGO  (A8QCB2), ARO1_MYCMD  (Q4P8F6), 
ARO1_PICST  (A3LSZ2), ARO1_SCHJY  (B6JVD0), ARO1_SCHPO  (Q9P7R0), 
ARO1_THACU  (Q8J294), ARODE_CHLMU (P56961), ARODE_CHLPN (Q9Z6M4), 
ARODE_CHLTR (O84375), AROD_AERPE  (Q9YEK1), AROD_ALBFT  (Q21VV5), 
AROD_ARCFU  (O30011), AROD_AROAE  (Q5P8W0), AROD_CLOK1  (B9E0D7), 
AROD_CLOK5  (A5N6W8), AROD_COXB1  (B6J6K1), AROD_COXB2  (B6J3T7), 
AROD_COXBN  (A9KDC5), AROD_COXBR  (A9N909), AROD_COXBU  (Q83A36), 
AROD_DEHM1  (Q3Z989), AROD_DEHMB  (A5FRZ6), AROD_DEHMC  (Q3ZZN2), 
AROD_GEOKA  (Q5KY94), AROD_GEOSW  (C5D2V7), AROD_GEOTN  (A4IPP2), 
AROD_HALMA  (Q5V145), AROD_HALS3  (B0R338), AROD_HALSA  (Q9HSB4), 
AROD_HALWD  (Q18DY7), AROD_IGNH4  (A8A962), AROD_LACLA  (Q9CF39), 
AROD_LACLM  (A2RJD1), AROD_LACLS  (Q02XM4), AROD_LACPL  (Q88SD8), 
AROD_LATSS  (Q38X91), AROD_METAC  (Q8THC4), AROD_METAR  (Q0W4B8), 
AROD_METB6  (A7I8M6), AROD_METBF  (Q46DZ7), AROD_METBU  (Q12UJ8), 
AROD_METHJ  (Q2FQV3), AROD_METKA  (Q8TY76), AROD_METMA  (Q8PXE7), 
AROD_METMJ  (A3CV25), AROD_METS3  (A5UJQ8), AROD_METS5  (A4YHV8), 
AROD_METST  (Q2NGS8), AROD_METTH  (O26666), AROD_METTP  (A0B6K7), 
AROD_NEIG1  (Q5F8N0), AROD_NEIG2  (B4RLX9), AROD_NEIMA  (Q9JTR9), 
AROD_NEIMB  (Q9JYT0), AROD_NEIMF  (A1KUQ1), AROD_PYRAB  (Q9V1H8), 
AROD_PYRAE  (Q8ZW59), AROD_SACS2  (Q980I4), AROD_SHOC1  (Q5WKM9), 
AROD_STAA1  (A7X013), AROD_STAA2  (A6TZT3), AROD_STAA3  (Q2FIJ1), 
AROD_STAA8  (Q2G002), AROD_STAA9  (A5IR07), AROD_STAAB  (Q2YWJ9), 
AROD_STAAC  (Q5HHL2), AROD_STAAE  (A6QFB2), AROD_STAAM  (P63586), 
AROD_STAAN  (P63587), AROD_STAAR  (Q6GII7), AROD_STAAS  (Q6GB27), 
AROD_STAAT  (A8Z1D4), AROD_STAAW  (Q8NXI0), AROD_STACT  (B9DJG9), 
AROD_STAEQ  (Q5HQR7), AROD_STAES  (Q8CPX1), AROD_STAHJ  (Q4L4R1), 
AROD_STAS1  (Q49W41), AROD_STRA1  (Q3K0D3), AROD_STRA3  (Q8E4F2), 
AROD_STRA5  (Q8DYU4), AROD_STRE4  (C0M8T8), AROD_STREM  (B4U2K6), 
AROD_STRGC  (A8AXZ6), AROD_STRMU  (Q8DUW4), AROD_STRP1  (P63590), 
AROD_STRP2  (Q04JX0), AROD_STRP3  (P0CZ74), AROD_STRP4  (B5E5N5), 
AROD_STRP6  (Q5XCT7), AROD_STRP7  (C1C7X8), AROD_STRP8  (P63592), 
AROD_STRPB  (Q1JCG7), AROD_STRPC  (Q1JME5), AROD_STRPD  (Q1JHJ2), 
AROD_STRPF  (Q1J7B3), AROD_STRPG  (A2RF79), AROD_STRPI  (B1ICH8), 
AROD_STRPJ  (B8ZKM6), AROD_STRPM  (Q48U89), AROD_STRPN  (P63588), 
AROD_STRPQ  (P0CZ75), AROD_STRPS  (B2IQJ5), AROD_STRPZ  (B5XKU3), 
AROD_STRR6  (P63589), AROD_STRS2  (A4W247), AROD_STRS7  (C0MGL4), 
AROD_STRSV  (A3CNV9), AROD_STRSY  (A4VVU0), AROD_STRT1  (Q5M0M2), 
AROD_STRT2  (Q5M558), AROD_STRTD  (Q03LH6), AROD_STRZJ  (C1CEW6), 
AROD_STRZP  (C1CL86), AROD_STRZT  (C1CQX8), AROD_SULAC  (Q4JC71), 
AROD_SULTO  (Q96Y90), AROD_SYNC1  (Q3A2I0), AROD_SYNFM  (A0LLU8), 
AROD_THEAC  (Q9HLV9), AROD_THEGJ  (C5A786), AROD_THEKO  (Q5JFV1), 
AROD_THEON  (B6YX10), AROD_THEVO  (Q97CA8), DHQSD_ARATH (Q9SQT8)

» more

PDB
[Detailed view]

36 PDB

1GQN; 1L9W; 1QFE; 2EGZ; 2YSW; 3JS3; 3L2I; 3LB0; 3M7W; 3NNT; 3O1N; 3OEX; 3S42; 4CLM; 4CNN; 4CNO; 4CNP; 4GFS; 4GUF; 4GUG; 4GUH; 4GUI; 4GUJ; 4H3D; 4IUO; 4PH6; 4UIO; 5SWU; 6H5C; 6H5D; 6H5G; 6H5J; 6SFE; 6SFG; 8B2B; 8B2C
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