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PROSITE entry PS01062


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General information about the entry

Entry name [info] HMG_COA_LYASE
Accession [info] PS01062
Entry type [info] PATTERN
Date [info] 01-NOV-1995 CREATED;
01-NOV-1995 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00813
Associated ProRule [info] PRU10115

Name and characterization of the entry

Description [info] Hydroxymethylglutaryl-coenzyme A lyase active site.
Pattern [info]
S-V-A-G-L-G-G-C-P-Y.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 9 in 9 different sequences
Number of true positive hits 9 in 9 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 5
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 64.29 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 8
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
9 sequences

HMGCL_BOVIN (Q29448), HMGCL_CHICK (P35915), HMGCL_HUMAN (P35914), 
HMGCL_MACFA (Q8HXZ6), HMGCL_MOUSE (P38060), HMGCL_PONAB (Q5R9E1), 
HMGCL_PSEMV (P13703), HMGCL_RAT   (P97519), LIUE_PSEAE  (Q9I2A0)
» more

UniProtKB/Swiss-Prot
False negative sequences
5 sequences

HMGC2_DANRE (A8WG57), HMGC2_HUMAN (Q8TB92), HMGC2_MOUSE (Q8JZS7), 
HMGC2_RAT   (D4A5C3), HMGCL_BACSU (O34873)
» more

PDB
[Detailed view]
5 PDB

2CW6; 2FTP; 3MP3; 3MP4; 3MP5