PROSITE entry PS01062
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General information about the entry
| Entry name [info] | HMG_COA_LYASE |
| Accession [info] | PS01062 |
| Entry type [info] | PATTERN |
| Date [info] |
01-NOV-1995 CREATED;
01-NOV-1995 DATA UPDATE; 08-NOV-2023 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00813 |
| Associated ProRule [info] | PRU10115 |
Name and characterization of the entry
| Description [info] | Hydroxymethylglutaryl-coenzyme A lyase active site. |
| Pattern [info] |
S-V-A-G-L-G-G-C-P-Y. |
Numerical results [info]
| Total number of hits | 9 in 9 different sequences |
| Number of true positive hits | 9 in 9 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 5 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 64.29 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes, Prokaryotes (Bacteria) |
| Maximum number of repetitions [info] | 1 |
| Site [info] | active_site at position 8 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
9 sequences
HMGCL_BOVIN (Q29448), HMGCL_CHICK (P35915), HMGCL_HUMAN (P35914), HMGCL_MACFA (Q8HXZ6), HMGCL_MOUSE (P38060), HMGCL_PONAB (Q5R9E1), HMGCL_PSEMV (P13703), HMGCL_RAT (P97519), LIUE_PSEAE (Q9I2A0)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
5 sequences
HMGC2_DANRE (A8WG57), HMGC2_HUMAN (Q8TB92), HMGC2_MOUSE (Q8JZS7), HMGC2_RAT (D4A5C3), HMGCL_BACSU (O34873)» more |
| PDB [Detailed view] |
5 PDB
2CW6; 2FTP; 3MP3; 3MP4; 3MP5 |