PROSITE entry PS01062
View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS01062 |
| Entry name [info] | HMG_COA_LYASE |
| Accession [info] | PS01062 |
| Entry type [info] | PATTERN |
| Date [info] |
01-NOV-1995 CREATED;
01-NOV-1995 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00813 |
| Associated ProRule [info] | PRU10115 |
Name and characterization of the entry
| Description [info] | Hydroxymethylglutaryl-coenzyme A lyase active site. |
| Pattern [info] |
S-V-A-G-L-G-G-C-P-Y. |
Numerical results [info]
| Total number of hits | 9 in 9 different sequences |
| Number of true positive hits | 9 in 9 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 5 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 64.29 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes, Prokaryotes (Bacteria) |
| Maximum number of repetitions [info] | 1 |
| Site [info] | active_site at position 8 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
9 sequences
HMGCL_BOVIN (Q29448), HMGCL_CHICK (P35915), HMGCL_HUMAN (P35914), HMGCL_MACFA (Q8HXZ6), HMGCL_MOUSE (P38060), HMGCL_PONAB (Q5R9E1), HMGCL_PSEMV (P13703), HMGCL_RAT (P97519), LIUE_PSEAE (Q9I2A0)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
5 sequences
HMGC2_DANRE (A8WG57), HMGC2_HUMAN (Q8TB92), HMGC2_MOUSE (Q8JZS7), HMGC2_RAT (D4A5C3), HMGCL_BACSU (O34873)» more |
| PDB [Detailed view] |
5 PDB
2CW6; 2FTP; 3MP3; 3MP4; 3MP5 |