ProRule PRU10115
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU10115 |
| Accession | PRU10115 |
| Dates | 16-OCT-2006 (Created)
14-OCT-2024 (Last updated, Version 7) |
| Data class | Domain; |
| Predictors |
PROSITE; PS01062; HMG_COA_LYASE |
Name | Hydroxymethylglutaryl-coenzyme A lyase active site |
| Function | Undefined |
| Scope(s) |
Eukaryota Bacteria |
| Example(s) | P35914 (HMGCL_HUMAN); |
Propagated annotation
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Identifier, protein and gene names
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| Protein name | AltName: Full=Hydroxymethylglutaryl-CoA lyase; EC=4.1.3.4; |
Comments
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| CATALYTIC ACTIVITY | Reaction=(3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl- CoA; Xref=Rhea:RHEA:24404, ChEBI:CHEBI:13705, ChEBI:CHEBI:43074, ChEBI:CHEBI:57288; EC=4.1.3.4; |
Features
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| From: PS01062 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 8 | 8 | ||||||||||
Additional information
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| Size range | unlimited amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
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UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Bacteria [3] Eukaryota [11] All [ 14 ]
- Retrieve set of proteins with 3D structure for this domain