PROSITE entry PS01070
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General information about the entry
| Entry name [info] | NUCLEASE_NON_SPEC |
| Accession [info] | PS01070 |
| Entry type [info] | PATTERN |
| Date [info] |
01-NOV-1995 CREATED;
01-JUL-1999 DATA UPDATE; 03-MAY-2023 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00821 |
| Associated ProRule [info] | PRU10047 |
Name and characterization of the entry
| Description [info] | DNA/RNA non-specific endonucleases active site. |
| Pattern [info] |
D-R-G-H-[QLIM]-x(3)-[AG]. |
Numerical results [info]
| Total number of hits | 17 in 17 different sequences |
| Number of true positive hits | 12 in 12 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 5 in 5 different sequences |
| Number of false negative sequences | 1 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 70.59 % |
| Recall (true positives / (true positives + false negatives)) | 92.31 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes, Prokaryotes (Bacteria) |
| Maximum number of repetitions [info] | 1 |
| Site [info] | active_site at position 4 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
12 sequences
NUC1_CUNEE (P81203 ), NUC1_SYNRA (P81204 ), NUC1_YEAST (P08466 ), NUCA_NOSS1 (P38446 ), NUCA_SERMA (P13717 ), NUCE_STRPN (P0A3S3 ), NUCE_STRR6 (P0A3S4 ), NUCG_BOVIN (P38447 ), NUCG_CAEEL (Q95NM6 ), NUCG_HUMAN (Q14249 ), NUCG_MOUSE (O08600 ), PNU1_SCHPO (Q10480 )» more
|
| UniProtKB/Swiss-Prot False negative sequences |
1 sequence
EXOG_HUMAN (Q9Y2C4 ) |
| UniProtKB/Swiss-Prot False positive sequences |
5 sequences
FFSA_ASPFV (A0A7L8UVC9), FHCA_METEA (C5B137 ), MURD_PSEPF (Q3K742 ), TGA6_ARATH (Q39140 ), Y4XK_SINFN (P55703 )» more |
| PDB [Detailed view] |
7 PDB
1G8T; 1QAE; 1QL0; 1SMN; 3S5B; 4E3Y; 4QN0 |