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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS01075


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PURL: https://purl.expasy.org/prosite/signature/PS01075

Direct ScanProsite submission
General information about the entry

Entry name [info] ACETATE_KINASE_1
Accession [info] PS01075
Entry type [info] PATTERN
Date [info] 01-NOV-1995 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00826

Name and characterization of the entry

Description [info] Acetate and butyrate kinases family signature 1.
Pattern [info] 
[LIVMFANT]-[LIVM]-x-[LIVMA]-N-x-G-S-[ST](2)-x-[KE].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 408 in 408 different sequences
Number of true positive hits 408 in 408 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 8
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 98.08 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 408 sequences 

ACKA1_ALIF1 (Q5E6L4), ACKA1_CLOPE (Q8XNW5), ACKA1_LACLA (Q9CE35), 

ACKA1_LATSS (Q9X4M1), ACKA1_LISIN (Q92BD4), ACKA1_LISMF (Q720R2), 
ACKA1_LISMO (Q8Y6V0), ACKA1_NEIMA (Q9JTM0), ACKA1_NEIMB (Q9JYM1), 
ACKA1_PHOPR (Q6LNF6), ACKA1_VIBCH (Q9KT07), ACKA1_VIBPA (Q87MZ4), 
ACKA1_VIBVU (Q8DAH8), ACKA1_VIBVY (Q7MJM8), ACKA2_ALIF1 (Q5DZD2), 
ACKA2_CLOPE (Q8XJN2), ACKA2_LACLA (Q9CE36), ACKA2_LISIN (Q92CN9), 
ACKA2_LISMF (Q71Z86), ACKA2_LISMO (Q8Y7V1), ACKA2_NEIMA (Q9JT07), 
ACKA2_NEIMB (Q9K0X1), ACKA2_PHOPR (Q6LLD4), ACKA2_VIBCH (Q9KMT5), 
ACKA2_VIBPA (Q87IJ5), ACKA2_VIBVU (Q8D7K4), ACKA2_VIBVY (Q7MEL2), 
ACKA_ACAM1  (B0CB11), ACKA_ACET2  (O52594), ACKA_ACHLI  (A9NFI4), 
ACKA_ACTP2  (A3N011), ACKA_ACTP7  (B3H169), ACKA_ACTPJ  (B0BNS1), 
ACKA_AGARV  (C4Z917), ACKA_ALKMQ  (A6TRU6), ACKA_ANOFW  (B7GGR2), 
ACKA_ARTS2  (A0JZZ4), ACKA_AYWBP  (Q2NIR6), ACKA_AZOPC  (B6YQE9), 
ACKA_BACAN  (Q81KV0), ACKA_BACC1  (Q72Z96), ACKA_BACCN  (A7GTR9), 
ACKA_BACCR  (Q817C0), ACKA_BACCZ  (Q633F8), ACKA_BACFN  (Q5LI41), 
ACKA_BACFR  (Q64Z48), ACKA_BACHK  (Q6HCP0), ACKA_BACLD  (Q65G65), 
ACKA_BACMK  (A9VKE9), ACKA_BACSU  (P37877), ACKA_BACTN  (Q8A1G8), 
ACKA_BACVZ  (A7Z7M2), ACKA_BAUCH  (Q1LT88), ACKA_BORBU  (O51567), 
ACKA_BORBZ  (B7J2I0), ACKA_BORDL  (B5RMH1), ACKA_BORGP  (Q660Q0), 
ACKA_BORHD  (B2S0W8), ACKA_BORRA  (B5RPW7), ACKA_BORT9  (A1R050), 
ACKA_BRAHW  (C0QWN8), ACKA_BUCAI  (P57272), ACKA_BUCBP  (Q89AS8), 
ACKA_BUCCC  (Q057V8), ACKA_CALBD  (B9MJT3), ACKA_CALS4  (Q8R9V4), 
ACKA_CALS8  (A4XL40), ACKA_CAMC1  (A7ZDP4), ACKA_CAMC5  (A7GYC8), 
ACKA_CAMFF  (A0RP54), ACKA_CAMHC  (A7I2H6), ACKA_CAMJ8  (A8FLB9), 
ACKA_CAMJD  (A7H4D5), ACKA_CAMJE  (Q9PPL8), ACKA_CAMJJ  (A1VZ44), 
ACKA_CAMJR  (Q5HV92), ACKA_CAMLR  (B9KFY4), ACKA_CARHZ  (Q3AC47), 
ACKA_CHAGB  (Q2HAJ4), ACKA_CHAYP  (O05278), ACKA_CHLT3  (B3QV27), 
ACKA_CHRVO  (Q7NXU5), ACKA_CLAM3  (A5CPD5), ACKA_CLASE  (B0RIG4), 
ACKA_CLOAB  (P71104), ACKA_CLOB1  (A7FW24), ACKA_CLOB6  (C3L0F7), 
ACKA_CLOB8  (A6LSL7), ACKA_CLOBA  (B2V4D1), ACKA_CLOBB  (B2TJ17), 
ACKA_CLOBH  (A5I4N7), ACKA_CLOBJ  (C1FSN0), ACKA_CLOBK  (B1II90), 
ACKA_CLOBL  (A7GG48), ACKA_CLOBM  (B1KWP9), ACKA_CLOD6  (Q18B36), 
ACKA_CLOK5  (A5N802), ACKA_CLONN  (A0Q0Z5), ACKA_CLOTE  (Q895N2), 
ACKA_COPPD  (B5Y7W0), ACKA_CORA7  (C3PJJ2), ACKA_CORDI  (Q6NF47), 
ACKA_COREF  (Q8FMB7), ACKA_CORGB  (A4QHF4), ACKA_CORGL  (P77845), 
ACKA_CORJK  (Q4JXQ4), ACKA_CROS8  (A7MH28), ACKA_CRYNB  (P0CL99), 
ACKA_CRYNJ  (P0CL98), ACKA_CYAP4  (B8HVB6), ACKA_DEIDV  (C1D087), 
ACKA_DEIGD  (Q1J2C9), ACKA_DEIRA  (Q9RR92), ACKA_DESDA  (B8J374), 
ACKA_DESHD  (B8FRT2), ACKA_DESHY  (Q24U35), ACKA_DESPS  (Q6AQT5), 
ACKA_DESRM  (A4J6A8), ACKA_DICNV  (A5EVU0), ACKA_DICT6  (B5YDP7), 
ACKA_DICTD  (B8E191), ACKA_ECO57  (P0A6A5), ACKA_ECOL6  (P0A6A4), 
ACKA_ECOLI  (P0A6A3), ACKA_ECTM1  (A4XYH6), ACKA_EMENI  (Q5B3G6), 
ACKA_ENDTX  (B1GZX0), ACKA_ENTFA  (Q833H0), ACKA_ERWT9  (B2VIP6), 
ACKA_EXIS2  (B1YKC5), ACKA_EXISA  (C4L493), ACKA_FERNB  (A7HL30), 
ACKA_FINM2  (B0S1N0), ACKA_FLAJ1  (A5FE24), ACKA_FRATO  (Q0BPA5), 
ACKA_FRUSA  (Q9F1X7), ACKA_FUSNN  (Q8RED7), ACKA_GEOKA  (Q5KW66), 
ACKA_GEOMG  (Q39WV0), ACKA_GEOSL  (Q749N5), ACKA_GEOSW  (C5D683), 
ACKA_GLAP5  (B8F420), ACKA_GLOC7  (B7KGG9), ACKA_GLOVI  (Q7NLW9), 
ACKA_HAEDU  (Q7VLI5), ACKA_HAEI8  (Q4QL95), ACKA_HAEIE  (A5UCQ6), 
ACKA_HAEIG  (A5UIW8), ACKA_HAEIN  (P44406), ACKA_HALOH  (B8CWV8), 
ACKA_HELAH  (Q17WE3), ACKA_HELHP  (Q7VGL3), ACKA_HELMI  (B0TGV2), 
ACKA_HELPJ  (Q9ZKU5), ACKA_HELPS  (B2UU54), ACKA_HISS1  (Q0I3R3), 
ACKA_HISS2  (B0UTZ5), ACKA_KOCRD  (B2GKK6), ACKA_LACP3  (Q03CP2), 
ACKA_LACP7  (A9KNV3), ACKA_LACPL  (Q88V41), ACKA_LAWIP  (Q1MRP0), 
ACKA_LEIXX  (Q6AGY7), ACKA_LIMF3  (B2GB54), ACKA_MACCJ  (B9E7B7), 
ACKA_MANSM  (Q65TV4), ACKA_MARSD  (C6BYL8), ACKA_MESFL  (Q6F273), 
ACKA_METAC  (Q8TK19), ACKA_METBF  (Q46BI1), ACKA_METMA  (P0CW05), 
ACKA_METMZ  (P0CW04), ACKA_METSB  (B8EIS2), ACKA_METTE  (P38502), 
ACKA_MICAN  (B0JMT8), ACKA_MICLC  (C5C8D9), ACKA_MOOTA  (Q2RJY3), 
ACKA_MYCA1  (A0QLU8), ACKA_MYCBO  (P63410), ACKA_MYCCT  (Q49113), 
ACKA_MYCGA  (Q7NAZ6), ACKA_MYCGE  (P47599), ACKA_MYCGI  (A4T166), 
ACKA_MYCMM  (B2HPZ3), ACKA_MYCMS  (Q6MTX5), ACKA_MYCPA  (Q73T33), 
ACKA_MYCPN  (P75245), ACKA_MYCPU  (Q98QX2), ACKA_MYCS2  (A0QQK1), 
ACKA_MYCSJ  (A3PTW3), ACKA_MYCSK  (A1UAA8), ACKA_MYCSS  (Q1BEM5), 
ACKA_MYCTO  (P9WQH0), ACKA_MYCTU  (P9WQH1), ACKA_MYCVP  (A1T2Y9), 
ACKA_NATTJ  (B2A8I5), ACKA_NEUCR  (Q7SH17), ACKA_NITHX  (Q1QPW6), 
ACKA_NITV2  (Q726S6), ACKA_NITV4  (A1VAA0), ACKA_NITV9  (B8DMG5), 
ACKA_NOCFA  (Q5YNP4), ACKA_NOSP7  (B2J068), ACKA_NOSS1  (Q8YU00), 
ACKA_OCEIH  (Q8EPB9), ACKA_OLEA2  (Q30WB0), ACKA_ONYPE  (Q6YR57), 
ACKA_PARD8  (A6LHA9), ACKA_PARUW  (Q6MBG3), ACKA_PASMU  (P57866), 
ACKA_PECAS  (Q6D2Q6), ACKA_PECCP  (C6DA54), ACKA_PHOLL  (Q7N2I1), 
ACKA_PHOV8  (A6KXS0), ACKA_PHYAS  (B1V924), ACKA_PHYMT  (B3QZW9), 
ACKA_PORG3  (B2RK02), ACKA_PORGI  (Q7MVI0), ACKA_PROMH  (B4EZD9), 
ACKA_PSEA8  (B7UYA0), ACKA_PSEAB  (Q02HZ4), ACKA_PSEAE  (Q9I5A4), 
ACKA_PSECP  (B8HF37), ACKA_PSELT  (A8F3X9), ACKA_PSEP7  (A6VAE3), 
ACKA_RHIME  (P58382), ACKA_RHIML  (Q9X449), ACKA_RHOPA  (Q6N143), 
ACKA_RHOPT  (B3QA57), ACKA_RICAH  (A8GM71), ACKA_RICFE  (Q4UNB0), 
ACKA_RICPR  (Q9ZE38), ACKA_RICTY  (Q68XX8), ACKA_RIPO1  (B7K4D0), 
ACKA_RUMCH  (B8I447), ACKA_SALTI  (P63412), ACKA_SALTY  (P63411), 
ACKA_SERP5  (A8GH24), ACKA_SHEAM  (A1S5P6), ACKA_SHEB2  (B8EEJ1), 
ACKA_SHEB5  (A3D600), ACKA_SHEB8  (A6WPT9), ACKA_SHEB9  (A9L605), 
ACKA_SHEFN  (Q080J4), ACKA_SHELP  (A3QFL1), ACKA_SHEON  (Q8ED55), 
ACKA_SHEPA  (A8H356), ACKA_SHEPC  (A4Y819), ACKA_SHESA  (A0KVG7), 
ACKA_SHESM  (Q0HK48), ACKA_SHESR  (Q0HWE9), ACKA_SHESW  (A1RIH0), 
ACKA_SHEWM  (B1KJX4), ACKA_SHOC1  (Q5WED5), ACKA_SODGM  (Q2NSJ4), 
ACKA_SOLUE  (Q022T0), ACKA_STAA1  (A7X3E0), ACKA_STAA2  (A6U2H8), 
ACKA_STAA3  (Q2FG27), ACKA_STAA8  (Q2FXL5), ACKA_STAA9  (A5ITN4), 
ACKA_STAAB  (Q2YTC9), ACKA_STAAC  (Q5HF63), ACKA_STAAE  (A6QHP5), 
ACKA_STAAM  (Q931P6), ACKA_STAAN  (Q99TF2), ACKA_STAAR  (Q6GFZ6), 
ACKA_STAAS  (Q6G8L6), ACKA_STAAT  (A8Z2M7), ACKA_STAAW  (Q8NW53), 
ACKA_STACT  (B9DN93), ACKA_STAEQ  (Q5HNJ4), ACKA_STAES  (Q8CS60), 
ACKA_STAHJ  (Q4L752), ACKA_STAS1  (Q49YE2), ACKA_STRA1  (Q3K3K1), 
ACKA_STRA3  (Q8E7I7), ACKA_STRA5  (Q8E231), ACKA_STRAW  (Q82JD1), 
ACKA_STRCO  (Q9L298), ACKA_STRE4  (C0M6X6), ACKA_STREM  (B4U063), 
ACKA_STRGC  (A8AZH2), ACKA_STRGG  (B1W052), ACKA_STRMU  (Q8DS57), 
ACKA_STRP1  (P63415), ACKA_STRP2  (Q04IC8), ACKA_STRP3  (P0CZ46), 
ACKA_STRP4  (B5E2W4), ACKA_STRP6  (Q5XE86), ACKA_STRP7  (C1CA89), 
ACKA_STRP8  (Q8P2X6), ACKA_STRPB  (Q1JE09), ACKA_STRPC  (Q1JNW6), 
ACKA_STRPD  (Q1JJ12), ACKA_STRPF  (Q1J8W0), ACKA_STRPG  (A2RC62), 
ACKA_STRPI  (B1I9A0), ACKA_STRPJ  (B8ZPA4), ACKA_STRPM  (Q48VQ0), 
ACKA_STRPN  (P63413), ACKA_STRPQ  (P0CZ47), ACKA_STRPZ  (B5XJD9), 
ACKA_STRR6  (P63414), ACKA_STRS7  (C0MEF7), ACKA_STRSY  (A4VSL6), 
ACKA_STRTD  (Q03IL2), ACKA_STRU0  (B9DT06), ACKA_STRZJ  (C1CGX4), 
ACKA_STRZP  (C1CMZ0), ACKA_STRZT  (C1CTV0), ACKA_STUS1  (A4VIM1), 
ACKA_SULNB  (A6QBT0), ACKA_SYMTH  (Q67L76), ACKA_SYNFM  (A0LIB0), 
ACKA_SYNJA  (Q2JRF6), ACKA_SYNJB  (Q2JLQ2), ACKA_SYNWW  (Q0AYW5), 
ACKA_SYNY3  (P73162), ACKA_THEAB  (B7IDH3), ACKA_THEM4  (A6LMG9), 
ACKA_THEMA  (Q9WYB1), ACKA_THEP1  (A5IKE7), ACKA_THEP3  (B0K9Y6), 
ACKA_THESQ  (B1L9M9), ACKA_THETC  (Q59331), ACKA_THEVB  (Q8DGH7), 
ACKA_TREDE  (Q73P66), ACKA_TREPA  (O83489), ACKA_TREPS  (B2S371), 
ACKA_TRIL1  (B3EB76), ACKA_TRIV2  (Q3MFX2), ACKA_VIBC1  (A7MVE1), 
ACKA_WIGBR  (Q8D320), ACKA_YERP3  (A7FGP4), ACKA_YERPA  (Q1C6A1), 
ACKA_YERPB  (B2K830), ACKA_YERPE  (Q8ZDJ6), ACKA_YERPG  (A9R6M9), 
ACKA_YERPN  (Q1CHP3), ACKA_YERPP  (A4TM44), ACKA_YERPS  (Q668Z0), 
ACKA_YERPY  (B1JGK4), BUK1_CALS4  (Q8R832), BUK1_CLOAB  (Q45829), 
BUK1_THEMA  (Q9X276), BUK2_CALS4  (Q8R828), BUK2_CLOAB  (Q97II1), 
BUK2_THEMA  (Q9X278), BUK_BACAA   (C3P7U3), BUK_BACAC   (C3LJT8), 
BUK_BACAN   (Q81M67), BUK_BACC0   (B7JM15), BUK_BACC1   (Q731D0), 
BUK_BACC2   (B7IXF5), BUK_BACC3   (C1ERN7), BUK_BACC4   (B7HB35), 
BUK_BACC7   (B7HNS7), BUK_BACCN   (A7GSI3), BUK_BACCQ   (B9IXF8), 
BUK_BACCR   (Q818T1), BUK_BACCZ   (Q635C1), BUK_BACHK   (Q6HE00), 
BUK_BACMK   (A9VGB0), BUK_BACSU   (P54532), BUK_BACTN   (Q8A4P5), 
BUK_CLOB8   (Q05619), BUK_CLOBA   (B2UYH0), BUK_CLOBB   (B2TIN4), 
BUK_CLOP1   (Q0TMV4), BUK_CLOPE   (P0C2D8), BUK_CLOPS   (Q0SQK0), 
BUK_CLOTE   (Q890U0), BUK_COPPD   (B5Y8N2), BUK_ENTFA   (Q9RPS7), 
BUK_EXIS2   (B1YLR4), BUK_GEOSE   (P54621), BUK_LISIN   (Q92BY5), 
BUK_LISMC   (C1L2S6), BUK_LISMF   (Q71ZV2), BUK_LISMH   (B8DFV8), 
BUK_LISMO   (Q8Y7B6), BUK_LISW6   (A0AIH1), BUK_MARSD   (C6BVJ0), 
BUK_OLEA2   (Q30WM4), BUK_THEP1   (A5ILI6), PDUW_CITFR  (B1VB81), 
PDUW_CITK8  (A8AEL8), PDUW_CITRI  (D2TPS5), PDUW_ESCF3  (B7LTX5), 
PDUW_KLEP3  (B5XUR6), PDUW_KLEP7  (A6TDE9), PDUW_SALPC  (C0Q1L8), 
PDUW_SALTY  (P74879), PDUW_TOLAT  (C4LFE6), PDUW_YERE8  (A1JTT9), 
TDCD_CITK8  (A8AQ07), TDCD_ECO57  (Q8XAF1), TDCD_ECOL6  (P59244), 
TDCD_ECOLI  (P11868), TDCD_EDWPI  (D0ZE10), TDCD_ENT38  (A4WEU0), 
TDCD_KLEP3  (B5XVZ8), TDCD_SALA4  (B5F6P9), TDCD_SALTD  (C9XHG0), 
TDCD_SALTI  (Q8Z3K5), TDCD_SALTY  (O06961), TDCD_YERE8  (A1JIM9)
» more

UniProtKB/Swiss-Prot
False negative sequences		 8 sequences 

ACKA_BUCAP  (Q8K9W6), ACKA_GEMAT  (C1A9T6), ACKA_HALH5  (Q9K815), 

ACKA_SULDN  (Q30UJ4), BUK_DEIRA   (Q9RVA9), BUK_ELUMP   (B2KEH0), 
BUK_OCEIH   (Q8CXE5), BUK_PHOV8   (A6KZZ5)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

BUK_CLOPA   (P81337)


				
	

	

		PDB
[Detailed view]		
		
			36 PDB
			


			pdb_00001g99; pdb_00001saz; pdb_00001tuu; pdb_00001tuy; pdb_00001x3m; pdb_00001x3n; pdb_00001x9j; pdb_00002e1y; pdb_00002e1z; pdb_00002e20; pdb_00002iir; pdb_00003p4i; 
			
				pdb_00003r9p; pdb_00003sk3; pdb_00003slc; pdb_00004dq8; pdb_00004fwk; pdb_00004fwl; pdb_00004fwm; pdb_00004fwn; pdb_00004fwo; pdb_00004fwp; pdb_00004fwq; pdb_00004fwr; 
				pdb_00004fws; pdb_00004ijn; pdb_00004iz9; pdb_00004xh1; pdb_00004xh4; pdb_00004xh5; pdb_00006ioy; pdb_00007fj7; pdb_00007fj8; pdb_00007fj9; pdb_00007fja; pdb_00007fjb
			
			

			» more