PROSITE logo
Black ribbon
We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS01076


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
PURL: https://purl.expasy.org/prosite/signature/PS01076

Direct ScanProsite submission
General information about the entry

Entry name [info] ACETATE_KINASE_2
Accession [info] PS01076
Entry type [info] PATTERN
Date [info] 01-NOV-1995 CREATED;
01-JAN-2002 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00826

Name and characterization of the entry

Description [info] Acetate and butyrate kinases family signature 2.
Pattern [info] 
[LIVMFATQ]-[LIVMA]-x(2)-H-x-G-x-[GT]-x-[ST]-[LIVMA]-x-[TAVC]-x(3)-G.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 395 in 395 different sequences
Number of true positive hits 388 in 388 different sequences
Number of 'unknown' hits 0
Number of false positive hits 7 in 7 different sequences
Number of false negative sequences 27
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 98.23 %
Recall (true positives / (true positives + false negatives)) 93.49 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 388 sequences 

ACKA1_ALIF1 (Q5E6L4), ACKA1_CLOPE (Q8XNW5), ACKA1_LACLA (Q9CE35), 

ACKA1_LATSS (Q9X4M1), ACKA1_LISIN (Q92BD4), ACKA1_LISMF (Q720R2), 
ACKA1_LISMO (Q8Y6V0), ACKA1_NEIMA (Q9JTM0), ACKA1_NEIMB (Q9JYM1), 
ACKA1_PHOPR (Q6LNF6), ACKA1_VIBCH (Q9KT07), ACKA1_VIBPA (Q87MZ4), 
ACKA1_VIBVU (Q8DAH8), ACKA1_VIBVY (Q7MJM8), ACKA2_ALIF1 (Q5DZD2), 
ACKA2_CLOPE (Q8XJN2), ACKA2_LACLA (Q9CE36), ACKA2_LISIN (Q92CN9), 
ACKA2_LISMF (Q71Z86), ACKA2_LISMO (Q8Y7V1), ACKA2_NEIMA (Q9JT07), 
ACKA2_NEIMB (Q9K0X1), ACKA2_PHOPR (Q6LLD4), ACKA2_VIBCH (Q9KMT5), 
ACKA2_VIBPA (Q87IJ5), ACKA2_VIBVU (Q8D7K4), ACKA2_VIBVY (Q7MEL2), 
ACKA_ACAM1  (B0CB11), ACKA_ACET2  (O52594), ACKA_ACHLI  (A9NFI4), 
ACKA_ACTP2  (A3N011), ACKA_ACTP7  (B3H169), ACKA_ACTPJ  (B0BNS1), 
ACKA_AGARV  (C4Z917), ACKA_ALKMQ  (A6TRU6), ACKA_ANOFW  (B7GGR2), 
ACKA_AYWBP  (Q2NIR6), ACKA_AZOPC  (B6YQE9), ACKA_BACAN  (Q81KV0), 
ACKA_BACC1  (Q72Z96), ACKA_BACCN  (A7GTR9), ACKA_BACCR  (Q817C0), 
ACKA_BACCZ  (Q633F8), ACKA_BACFN  (Q5LI41), ACKA_BACFR  (Q64Z48), 
ACKA_BACHK  (Q6HCP0), ACKA_BACLD  (Q65G65), ACKA_BACMK  (A9VKE9), 
ACKA_BACSU  (P37877), ACKA_BACTN  (Q8A1G8), ACKA_BACVZ  (A7Z7M2), 
ACKA_BAUCH  (Q1LT88), ACKA_BORBU  (O51567), ACKA_BORBZ  (B7J2I0), 
ACKA_BORDL  (B5RMH1), ACKA_BORGP  (Q660Q0), ACKA_BORHD  (B2S0W8), 
ACKA_BORRA  (B5RPW7), ACKA_BORT9  (A1R050), ACKA_BRAHW  (C0QWN8), 
ACKA_BUCAI  (P57272), ACKA_BUCAP  (Q8K9W6), ACKA_BUCBP  (Q89AS8), 
ACKA_BUCCC  (Q057V8), ACKA_CALBD  (B9MJT3), ACKA_CALS4  (Q8R9V4), 
ACKA_CALS8  (A4XL40), ACKA_CAMC1  (A7ZDP4), ACKA_CAMC5  (A7GYC8), 
ACKA_CAMHC  (A7I2H6), ACKA_CAMJ8  (A8FLB9), ACKA_CAMJD  (A7H4D5), 
ACKA_CAMJE  (Q9PPL8), ACKA_CAMJJ  (A1VZ44), ACKA_CAMJR  (Q5HV92), 
ACKA_CAMLR  (B9KFY4), ACKA_CARHZ  (Q3AC47), ACKA_CHAGB  (Q2HAJ4), 
ACKA_CHAYP  (O05278), ACKA_CHLT3  (B3QV27), ACKA_CHRVO  (Q7NXU5), 
ACKA_CLAM3  (A5CPD5), ACKA_CLASE  (B0RIG4), ACKA_CLOAB  (P71104), 
ACKA_CLOB1  (A7FW24), ACKA_CLOB6  (C3L0F7), ACKA_CLOB8  (A6LSL7), 
ACKA_CLOBA  (B2V4D1), ACKA_CLOBB  (B2TJ17), ACKA_CLOBH  (A5I4N7), 
ACKA_CLOBJ  (C1FSN0), ACKA_CLOBK  (B1II90), ACKA_CLOBL  (A7GG48), 
ACKA_CLOBM  (B1KWP9), ACKA_CLOD6  (Q18B36), ACKA_CLOK5  (A5N802), 
ACKA_CLONN  (A0Q0Z5), ACKA_CLOTE  (Q895N2), ACKA_COPPD  (B5Y7W0), 
ACKA_CORA7  (C3PJJ2), ACKA_COREF  (Q8FMB7), ACKA_CORGB  (A4QHF4), 
ACKA_CORGL  (P77845), ACKA_CORJK  (Q4JXQ4), ACKA_CROS8  (A7MH28), 
ACKA_CYAP4  (B8HVB6), ACKA_DEIDV  (C1D087), ACKA_DEIGD  (Q1J2C9), 
ACKA_DEIRA  (Q9RR92), ACKA_DESHD  (B8FRT2), ACKA_DESHY  (Q24U35), 
ACKA_DESPS  (Q6AQT5), ACKA_DESRM  (A4J6A8), ACKA_DICNV  (A5EVU0), 
ACKA_DICT6  (B5YDP7), ACKA_DICTD  (B8E191), ACKA_ECO57  (P0A6A5), 
ACKA_ECOL6  (P0A6A4), ACKA_ECOLI  (P0A6A3), ACKA_EMENI  (Q5B3G6), 
ACKA_ENDTX  (B1GZX0), ACKA_ENTFA  (Q833H0), ACKA_ERWT9  (B2VIP6), 
ACKA_EXIS2  (B1YKC5), ACKA_EXISA  (C4L493), ACKA_FERNB  (A7HL30), 
ACKA_FINM2  (B0S1N0), ACKA_FLAJ1  (A5FE24), ACKA_FRATO  (Q0BPA5), 
ACKA_FUSNN  (Q8RED7), ACKA_GEMAT  (C1A9T6), ACKA_GEOKA  (Q5KW66), 
ACKA_GEOSW  (C5D683), ACKA_GLAP5  (B8F420), ACKA_GLOC7  (B7KGG9), 
ACKA_GLOVI  (Q7NLW9), ACKA_HAEDU  (Q7VLI5), ACKA_HAEI8  (Q4QL95), 
ACKA_HAEIE  (A5UCQ6), ACKA_HAEIG  (A5UIW8), ACKA_HAEIN  (P44406), 
ACKA_HALH5  (Q9K815), ACKA_HALOH  (B8CWV8), ACKA_HELAH  (Q17WE3), 
ACKA_HELHP  (Q7VGL3), ACKA_HELMI  (B0TGV2), ACKA_HELPJ  (Q9ZKU5), 
ACKA_HELPS  (B2UU54), ACKA_HISS1  (Q0I3R3), ACKA_HISS2  (B0UTZ5), 
ACKA_KOCRD  (B2GKK6), ACKA_LACP3  (Q03CP2), ACKA_LACP7  (A9KNV3), 
ACKA_LACPL  (Q88V41), ACKA_LAWIP  (Q1MRP0), ACKA_LEIXX  (Q6AGY7), 
ACKA_LIMF3  (B2GB54), ACKA_MACCJ  (B9E7B7), ACKA_MANSM  (Q65TV4), 
ACKA_MARSD  (C6BYL8), ACKA_MESFL  (Q6F273), ACKA_METAC  (Q8TK19), 
ACKA_METBF  (Q46BI1), ACKA_METMA  (P0CW05), ACKA_METMZ  (P0CW04), 
ACKA_METSB  (B8EIS2), ACKA_METTE  (P38502), ACKA_MICAN  (B0JMT8), 
ACKA_MYCBO  (P63410), ACKA_MYCCT  (Q49113), ACKA_MYCGE  (P47599), 
ACKA_MYCGI  (A4T166), ACKA_MYCMM  (B2HPZ3), ACKA_MYCMS  (Q6MTX5), 
ACKA_MYCPN  (P75245), ACKA_MYCS2  (A0QQK1), ACKA_MYCSJ  (A3PTW3), 
ACKA_MYCSK  (A1UAA8), ACKA_MYCSS  (Q1BEM5), ACKA_MYCTO  (P9WQH0), 
ACKA_MYCTU  (P9WQH1), ACKA_MYCVP  (A1T2Y9), ACKA_NATTJ  (B2A8I5), 
ACKA_NEUCR  (Q7SH17), ACKA_NITHX  (Q1QPW6), ACKA_NITV2  (Q726S6), 
ACKA_NITV4  (A1VAA0), ACKA_NITV9  (B8DMG5), ACKA_NOCFA  (Q5YNP4), 
ACKA_NOSP7  (B2J068), ACKA_NOSS1  (Q8YU00), ACKA_OCEIH  (Q8EPB9), 
ACKA_OLEA2  (Q30WB0), ACKA_ONYPE  (Q6YR57), ACKA_PARD8  (A6LHA9), 
ACKA_PARUW  (Q6MBG3), ACKA_PASMU  (P57866), ACKA_PECAS  (Q6D2Q6), 
ACKA_PECCP  (C6DA54), ACKA_PHOLL  (Q7N2I1), ACKA_PHOV8  (A6KXS0), 
ACKA_PHYAS  (B1V924), ACKA_PORG3  (B2RK02), ACKA_PORGI  (Q7MVI0), 
ACKA_PROMH  (B4EZD9), ACKA_PSECP  (B8HF37), ACKA_PSELT  (A8F3X9), 
ACKA_RHIME  (P58382), ACKA_RICAH  (A8GM71), ACKA_RICFE  (Q4UNB0), 
ACKA_RICPR  (Q9ZE38), ACKA_RICTY  (Q68XX8), ACKA_RIPO1  (B7K4D0), 
ACKA_RUMCH  (B8I447), ACKA_SALTI  (P63412), ACKA_SALTY  (P63411), 
ACKA_SERP5  (A8GH24), ACKA_SHEAM  (A1S5P6), ACKA_SHEB2  (B8EEJ1), 
ACKA_SHEB5  (A3D600), ACKA_SHEB8  (A6WPT9), ACKA_SHEB9  (A9L605), 
ACKA_SHEFN  (Q080J4), ACKA_SHELP  (A3QFL1), ACKA_SHEON  (Q8ED55), 
ACKA_SHEPA  (A8H356), ACKA_SHEPC  (A4Y819), ACKA_SHESA  (A0KVG7), 
ACKA_SHESM  (Q0HK48), ACKA_SHESR  (Q0HWE9), ACKA_SHESW  (A1RIH0), 
ACKA_SHEWM  (B1KJX4), ACKA_SHOC1  (Q5WED5), ACKA_SODGM  (Q2NSJ4), 
ACKA_SOLUE  (Q022T0), ACKA_STAA1  (A7X3E0), ACKA_STAA2  (A6U2H8), 
ACKA_STAA3  (Q2FG27), ACKA_STAA8  (Q2FXL5), ACKA_STAA9  (A5ITN4), 
ACKA_STAAB  (Q2YTC9), ACKA_STAAC  (Q5HF63), ACKA_STAAE  (A6QHP5), 
ACKA_STAAM  (Q931P6), ACKA_STAAN  (Q99TF2), ACKA_STAAR  (Q6GFZ6), 
ACKA_STAAS  (Q6G8L6), ACKA_STAAT  (A8Z2M7), ACKA_STAAW  (Q8NW53), 
ACKA_STACT  (B9DN93), ACKA_STAEQ  (Q5HNJ4), ACKA_STAES  (Q8CS60), 
ACKA_STAHJ  (Q4L752), ACKA_STAS1  (Q49YE2), ACKA_STRA1  (Q3K3K1), 
ACKA_STRA3  (Q8E7I7), ACKA_STRA5  (Q8E231), ACKA_STRAW  (Q82JD1), 
ACKA_STRCO  (Q9L298), ACKA_STRE4  (C0M6X6), ACKA_STREM  (B4U063), 
ACKA_STRGC  (A8AZH2), ACKA_STRGG  (B1W052), ACKA_STRMU  (Q8DS57), 
ACKA_STRP1  (P63415), ACKA_STRP2  (Q04IC8), ACKA_STRP3  (P0CZ46), 
ACKA_STRP4  (B5E2W4), ACKA_STRP6  (Q5XE86), ACKA_STRP7  (C1CA89), 
ACKA_STRP8  (Q8P2X6), ACKA_STRPB  (Q1JE09), ACKA_STRPC  (Q1JNW6), 
ACKA_STRPD  (Q1JJ12), ACKA_STRPF  (Q1J8W0), ACKA_STRPG  (A2RC62), 
ACKA_STRPI  (B1I9A0), ACKA_STRPJ  (B8ZPA4), ACKA_STRPM  (Q48VQ0), 
ACKA_STRPN  (P63413), ACKA_STRPQ  (P0CZ47), ACKA_STRPZ  (B5XJD9), 
ACKA_STRR6  (P63414), ACKA_STRS7  (C0MEF7), ACKA_STRSY  (A4VSL6), 
ACKA_STRTD  (Q03IL2), ACKA_STRU0  (B9DT06), ACKA_STRZJ  (C1CGX4), 
ACKA_STRZP  (C1CMZ0), ACKA_STRZT  (C1CTV0), ACKA_SULDN  (Q30UJ4), 
ACKA_SULNB  (A6QBT0), ACKA_SYMTH  (Q67L76), ACKA_SYNFM  (A0LIB0), 
ACKA_SYNJA  (Q2JRF6), ACKA_SYNJB  (Q2JLQ2), ACKA_SYNWW  (Q0AYW5), 
ACKA_SYNY3  (P73162), ACKA_THEAB  (B7IDH3), ACKA_THEM4  (A6LMG9), 
ACKA_THEMA  (Q9WYB1), ACKA_THEP1  (A5IKE7), ACKA_THEP3  (B0K9Y6), 
ACKA_THESQ  (B1L9M9), ACKA_THETC  (Q59331), ACKA_THEVB  (Q8DGH7), 
ACKA_TREDE  (Q73P66), ACKA_TREPA  (O83489), ACKA_TREPS  (B2S371), 
ACKA_TRIV2  (Q3MFX2), ACKA_VIBC1  (A7MVE1), ACKA_WIGBR  (Q8D320), 
ACKA_YERP3  (A7FGP4), ACKA_YERPA  (Q1C6A1), ACKA_YERPB  (B2K830), 
ACKA_YERPE  (Q8ZDJ6), ACKA_YERPG  (A9R6M9), ACKA_YERPN  (Q1CHP3), 
ACKA_YERPP  (A4TM44), ACKA_YERPS  (Q668Z0), ACKA_YERPY  (B1JGK4), 
BUK1_CALS4  (Q8R832), BUK1_CLOAB  (Q45829), BUK1_THEMA  (Q9X276), 
BUK2_CALS4  (Q8R828), BUK2_CLOAB  (Q97II1), BUK2_THEMA  (Q9X278), 
BUK_BACAA   (C3P7U3), BUK_BACAC   (C3LJT8), BUK_BACAN   (Q81M67), 
BUK_BACC0   (B7JM15), BUK_BACC1   (Q731D0), BUK_BACC2   (B7IXF5), 
BUK_BACC3   (C1ERN7), BUK_BACC4   (B7HB35), BUK_BACC7   (B7HNS7), 
BUK_BACCN   (A7GSI3), BUK_BACCQ   (B9IXF8), BUK_BACCR   (Q818T1), 
BUK_BACCZ   (Q635C1), BUK_BACHK   (Q6HE00), BUK_BACMK   (A9VGB0), 
BUK_BACSU   (P54532), BUK_BACTN   (Q8A4P5), BUK_CLOB8   (Q05619), 
BUK_CLOBA   (B2UYH0), BUK_CLOBB   (B2TIN4), BUK_CLOP1   (Q0TMV4), 
BUK_CLOPE   (P0C2D8), BUK_CLOPS   (Q0SQK0), BUK_CLOTE   (Q890U0), 
BUK_COPPD   (B5Y8N2), BUK_DEIRA   (Q9RVA9), BUK_ELUMP   (B2KEH0), 
BUK_ENTFA   (Q9RPS7), BUK_EXIS2   (B1YLR4), BUK_LISIN   (Q92BY5), 
BUK_LISMC   (C1L2S6), BUK_LISMF   (Q71ZV2), BUK_LISMH   (B8DFV8), 
BUK_LISMO   (Q8Y7B6), BUK_LISW6   (A0AIH1), BUK_MARSD   (C6BVJ0), 
BUK_OLEA2   (Q30WM4), BUK_PHOV8   (A6KZZ5), BUK_THEP1   (A5ILI6), 
PDUW_CITFR  (B1VB81), PDUW_CITK8  (A8AEL8), PDUW_CITRI  (D2TPS5), 
PDUW_ESCF3  (B7LTX5), PDUW_KLEP3  (B5XUR6), PDUW_KLEP7  (A6TDE9), 
PDUW_SALPC  (C0Q1L8), PDUW_SALTY  (P74879), PDUW_TOLAT  (C4LFE6), 
PDUW_YERE8  (A1JTT9), TDCD_CITK8  (A8AQ07), TDCD_ECO57  (Q8XAF1), 
TDCD_ECOL6  (P59244), TDCD_ECOLI  (P11868), TDCD_EDWPI  (D0ZE10), 
TDCD_ENT38  (A4WEU0), TDCD_KLEP3  (B5XVZ8), TDCD_SALA4  (B5F6P9), 
TDCD_SALTD  (C9XHG0), TDCD_SALTI  (Q8Z3K5), TDCD_SALTY  (O06961), 
TDCD_YERE8  (A1JIM9)
» more

UniProtKB/Swiss-Prot
False negative sequences		 27 sequences 

ACKA_ARTS2  (A0JZZ4), ACKA_CAMFF  (A0RP54), ACKA_CORDI  (Q6NF47), 

ACKA_CRYNB  (P0CL99), ACKA_CRYNJ  (P0CL98), ACKA_DESDA  (B8J374), 
ACKA_ECTM1  (A4XYH6), ACKA_FRUSA  (Q9F1X7), ACKA_GEOMG  (Q39WV0), 
ACKA_GEOSL  (Q749N5), ACKA_MICLC  (C5C8D9), ACKA_MOOTA  (Q2RJY3), 
ACKA_MYCA1  (A0QLU8), ACKA_MYCGA  (Q7NAZ6), ACKA_MYCPA  (Q73T33), 
ACKA_MYCPU  (Q98QX2), ACKA_PHYMT  (B3QZW9), ACKA_PSEA8  (B7UYA0), 
ACKA_PSEAB  (Q02HZ4), ACKA_PSEAE  (Q9I5A4), ACKA_PSEP7  (A6VAE3), 
ACKA_RHIML  (Q9X449), ACKA_RHOPA  (Q6N143), ACKA_RHOPT  (B3QA57), 
ACKA_STUS1  (A4VIM1), ACKA_TRIL1  (B3EB76), BUK_OCEIH   (Q8CXE5)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 2 sequences 

BUK_CLOPA   (P81337), BUK_GEOSE   (P54621)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			7 sequences
			


			
CLRA_IDEDE  (P60068), ELMGT_STROV (Q9F2F9), FPG_GEOSL   (Q74EG5), 

			
NOVM_STRNV  (Q9L9F5), PG05_MYCTU  (Q6MX50), SERA_THASE  (Q9S1H0), 
TYLN_STRFR  (O70023)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			33 PDB
			


			pdb_00001g99; pdb_00001saz; pdb_00001tuu; pdb_00001tuy; pdb_00001x3m; pdb_00001x3n; pdb_00001x9j; pdb_00002e1y; pdb_00002e1z; pdb_00002e20; pdb_00002iir; pdb_00003sk3; 
			
				pdb_00003slc; pdb_00004dq8; pdb_00004fwk; pdb_00004fwl; pdb_00004fwm; pdb_00004fwn; pdb_00004fwo; pdb_00004fwp; pdb_00004fwq; pdb_00004fwr; pdb_00004fws; pdb_00004ijn; 
				pdb_00004xh1; pdb_00004xh4; pdb_00004xh5; pdb_00006ioy; pdb_00007fj7; pdb_00007fj8; pdb_00007fj9; pdb_00007fja; pdb_00007fjb
			
			

			» more