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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
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Amos Bairoch

PROSITE entry PS01116


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PURL: https://purl.expasy.org/prosite/signature/PS01116

Direct ScanProsite submission
General information about the entry

Entry name [info] XANTH_URACIL_PERMASE
Accession [info] PS01116
Entry type [info] PATTERN
Date [info] 01-NOV-1995 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00860

Name and characterization of the entry

Description [info] Xanthine/uracil permeases family signature.
Pattern [info]
[LIVM]-P-x-[PASIF]-V-[LIVMG]-[GF]-[GA]-x(4)-[LIVM]-[FY]-[GSA]-x-[LIVM]-
x(3)-[GA].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 29 in 29 different sequences
Number of true positive hits 29 in 29 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 26
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 52.73 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
29 sequences

NUCLP_PAELB (A0A2A5JY22), PBUX_BACSU  (P42086), PUCJ_BACSU  (O32139), 
PUCK_BACSU  (O32140), PYRP_BACCL  (P41006), PYRP_BACSU  (P39766), 
RUTG_ECOLI  (P75892), S23A2_HUMAN (Q9UGH3), S23A2_MOUSE (Q9EPR4), 
S23A2_RAT   (Q9WTW8), S23A2_XENTR (B0JZG0), UACT_ECOLI  (Q46821), 
UAPA_EMENI  (Q07307), UAPC_EMENI  (P48777), URAA_ECO57  (P0AGM8), 
URAA_ECOLI  (P0AGM7), URAA_HAEIN  (P45117), URAA_PASMU  (Q9CPL9), 
URAP_PAELB  (A0A2A5K1W4), XANP_ECO57  (P0AGN1), XANP_ECOL6  (P0AGN0), 
XANP_ECOLI  (P0AGM9), XANP_SHIFL  (P0AGN2), XANQ_ECO57  (P67446), 
XANQ_ECOL6  (P67445), XANQ_ECOLI  (P67444), Y397_CLOPE  (P50487), 
YI31_SCHPO  (Q9HE12), YWDJ_BACSU  (P39618)
» more

UniProtKB/Swiss-Prot
False negative sequences
26 sequences

ADEP_ECOLI  (P31466), ADEQ_ECOLI  (P31440), AZG1_PAELB  (A0A2A5K5H4), 
AZG2_PAELB  (A0A2A5K485), GHXP_ECO57  (P0AF53), GHXP_ECOLI  (P0AF52), 
GHXQ_ECOLI  (Q46817), LPE1_MAIZE  (Q41760), NAT10_ARATH (O04472), 
NAT11_ARATH (Q6SZ87), NAT12_ARATH (Q3E7D0), NAT1_ARATH  (Q9SHZ3), 
NAT2_ARATH  (Q94C70), NAT3_ARATH  (Q8GZD4), NAT4_ARATH  (P93039), 
NAT5_ARATH  (Q8RWE9), NAT6_ARATH  (Q27GI3), NAT7_ARATH  (Q0WPE9), 
NAT8_ARATH  (Q8VZQ5), NBAT9_ARATH (Q3E956), PBUG_BACSU  (O34987), 
PBUO_BACSU  (O34978), Y125_HAEIN  (P44530), Y326_METJA  (Q57772), 
YBBY_ECOLI  (P77328), YOOH_SCHPO  (O94300)
» more

PDB
[Detailed view]
5 PDB

pdb_00003qe7; pdb_00005i6c; pdb_00005xls; pdb_00008omz; pdb_00008oo1