PROSITE entry PS01129

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS01129
Entry name [info]	PSI_RLU
Accession [info]	PS01129
Entry type [info]	PATTERN
Date [info]	01-NOV-1995 CREATED; 01-APR-2006 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00869

Name and characterization of the entry

Description [info]	Rlu family of pseudouridine synthase signature.
Pattern [info]	[LIVCA]-[NHYTQ]-R-[LI]-[DG]-x(2)-[TV]-[STAC]-G-[LIVAGC]-[LIVMF](2)- [LIVMFGCA]-[SGTACV].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	125 in 125 different sequences
Number of true positive hits	125 in 125 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	13
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	90.58 %

Comments [info]

Taxonomic range [info]	Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Version [info]	2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

125 sequences

PUS1_ARATH  (Q7XA65), PUS1_ORYSJ  (Q2QNM3), PUS2_ARATH  (Q3ECD0),

PUS2_ORYSJ  (Q5Z8P2), PUS3_ARATH  (Q5XET6), PUS5_ARATH  (Q5M721), 
PUS5_CANAL  (Q5A0Y2), PUS5_DEBHA  (Q6BNX8), PUS5_EREGS  (Q750S3), 
PUS5_ORYSJ  (Q0DST9), PUS5_YEAST  (Q06244), PUS6_YEAST  (P53294), 
PUS7_ARATH  (Q9LU60), PUS7_ORYSJ  (Q0E0Y3), PUS9_YEAST  (Q12069), 
RIB2_YEAST  (Q12362), RLUA_ECO57  (Q8XA10), RLUA_ECOL6  (Q8FL93), 
RLUA_ECOLI  (P0AA37), RLUA_HAEDU  (P59831), RLUA_HAEIN  (P44782), 
RLUA_PASMU  (Q9CK02), RLUA_SALTI  (Q8Z9J5), RLUA_SALTY  (Q8ZRV9), 
RLUA_SHIFL  (P0AA38), RLUA_VIBCH  (Q9KP71), RLUA_VIBPA  (Q87LD3), 
RLUA_VIBVU  (Q8DCG0), RLUA_YERPE  (Q8ZIK1), RLUC_BUCAI  (P57430), 
RLUC_BUCAP  (Q8K9J8), RLUC_BUCBP  (Q89AH2), RLUC_ECO57  (Q8X8J3), 
RLUC_ECOL6  (Q8FIP7), RLUC_ECOLI  (P0AA39), RLUC_HAEDU  (P59835), 
RLUC_HAEIN  (P44433), RLUC_PASMU  (Q9CM51), RLUC_PSEAE  (Q9HZM9), 
RLUC_RICBR  (Q1RJX7), RLUC_RICCN  (Q92IS6), RLUC_RICFE  (Q4UKQ3), 
RLUC_RICPR  (Q9ZDR7), RLUC_RICTY  (Q68XB2), RLUC_SALTI  (Q8Z7J7), 
RLUC_SALTY  (Q8ZQ16), RLUC_SHIFL  (P0AA40), RLUC_VIBCH  (Q9KQH0), 
RLUC_VIBPA  (Q87N15), RLUC_VIBVU  (Q8D8G1), RLUC_YERPE  (Q8ZFU1), 
RLUD_BLOFL  (P59838), RLUD_BORBU  (P70870), RLUD_BUCAI  (P57481), 
RLUD_BUCAP  (Q8K9E9), RLUD_BUCBP  (Q89AD9), RLUD_ECO57  (Q8X9F0), 
RLUD_ECOL6  (P65834), RLUD_ECOLI  (P33643), RLUD_HAEDU  (Q9L7A7), 
RLUD_HAEIN  (P44445), RLUD_NEIMA  (Q9JVB6), RLUD_NEIMB  (Q9K0B0), 
RLUD_NITEU  (Q82WZ5), RLUD_PASMU  (Q9CKA6), RLUD_PSEAE  (P33640), 
RLUD_RALN1  (Q8XYX8), RLUD_SALTI  (P65837), RLUD_SALTY  (P65836), 
RLUD_SHIFL  (P65835), RLUD_VIBCH  (Q9KU20), RLUD_VIBPA  (Q87S65), 
RLUD_VIBVU  (Q8DEV0), RLUD_XANAC  (Q8PHN2), RLUD_XANCP  (Q8P682), 
RLUD_XYLFA  (Q9PET9), RLUD_XYLFT  (Q87AR7), RLUD_YERPE  (Q8ZBV7), 
RLUD_ZYMMO  (P50513), RUSD2_HUMAN (Q8IZ73), RUSD2_MOUSE (Q149F1), 
RUSD4_BOVIN (Q5E9Z1), RUSD4_HUMAN (Q96CM3), RUSD4_MOUSE (Q9CWX4), 
RUSD4_RAT   (Q4QQT0), RUSD4_XENTR (Q28C59), TRUC_ECO57  (Q8X6T6), 
TRUC_ECOL6  (Q8FEF9), TRUC_ECOLI  (P0AA41), TRUC_HAEDU  (P59840), 
TRUC_HAEIN  (P44197), TRUC_PASMU  (Q9CNF3), TRUC_PECCC  (Q47417), 
TRUC_SALTI  (Q8Z439), TRUC_SALTY  (Q8ZMD5), TRUC_SHIFL  (P0AA42), 
TRUC_VIBCH  (Q9KTL4), TRUC_VIBPA  (Q87MD4), TRUC_VIBVU  (Q8DBG5), 
TRUC_YERPE  (Q8ZH72), Y042_HAEIN  (P43930), Y1540_MYCTO (P9WHQ2), 
Y1540_MYCTU (P9WHQ3), Y1567_MYCBO (P0A5T3), Y1592_SYNY3 (P72970), 
Y1629_SYNY3 (P74346), Y1758_AQUAE (O67638), Y209_MYCGE  (P47451), 
Y292_MYCPN  (P75485), Y347_HELPJ  (Q9ZMA1), Y347_HELPY  (O25114), 
Y370_MYCGE  (P47610), Y505_ZYMMO  (O66114), Y548_MYCPN  (P75230), 
Y723_CHLP8  (O50310), Y745_HELPJ  (Q9ZL98), Y745_HELPY  (O25441), 
Y901_CHLAA  (Q45826), Y956_HELPJ  (Q9ZKP5), Y956_HELPY  (O25610), 
YA32_SCHPO  (Q09709), YHCT_BACSU  (P54604), YJBO_BACSU  (O31613), 
YK27_CAEEL  (O16686), YLYB_BACSU  (Q45480)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

13 sequences

PUS3_ORYSJ  (Q0J4D4), PUS4_ARATH  (Q9LT72), PUS4_ORYSJ  (Q69K07),

PUS6_ARATH  (Q9SVS0), RUSD1_BOVIN (Q17QT4), RUSD1_DANRE (Q08C69), 
RUSD1_HUMAN (Q9UJJ7), RUSD1_MOUSE (Q8VCZ8), RUSD3_BOVIN (Q2TBK7), 
RUSD3_HUMAN (Q6P087), RUSD3_MOUSE (Q14AI6), RUSD4_DANRE (Q6DBR0), 
Y714_MYCCT  (P45614)

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PDB
[Detailed view]

9 PDB

1PRZ; 1QYU; 1V9F; 1V9K; 1XPI; 2I82; 2IST; 5UBA; 7BL5