PROSITE entry PS01192
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General information about the entry
| Entry name [info] | HMG_COA_REDUCTASE_3 |
| Accession [info] | PS01192 |
| Entry type [info] | PATTERN |
| Date [info] |
01-NOV-1997 CREATED;
01-NOV-1997 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00064 |
| Associated ProRule [info] | PRU10003 |
Name and characterization of the entry
| Description [info] | Hydroxymethylglutaryl-coenzyme A reductases signature 3. |
| Pattern [info] |
A-[LIVM]-x-[STAN]-x(2)-[LI]-x-[KRNQ]-[GSA]-H-[LM]-x-[FYLH]. |
Numerical results [info]
| Total number of hits | 56 in 56 different sequences |
| Number of true positive hits | 56 in 56 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 11 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 83.58 % |
Comments [info]
| Taxonomic range [info] | Archaea, Eukaryotes, Prokaryotes (Bacteria) |
| Maximum number of repetitions [info] | 1 |
| Site [info] | active_site at position 10 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
56 sequences
HMDH1_ARATH (P14891), HMDH1_ASPFU (Q4WHZ1), HMDH1_DICDI (P34135), HMDH1_GIBZE (I1RXX1), HMDH1_GOSHI (O64966), HMDH1_HEVBR (P29057), HMDH1_ORYSI (A2X8W3), HMDH1_ORYSJ (Q0DY59), HMDH1_SOLTU (P48020), HMDH1_YEAST (P12683), HMDH2_ARATH (P43256), HMDH2_CAPAN (Q9XEL8), HMDH2_DICDI (P34136), HMDH2_GOSHI (O64967), HMDH2_HEVBR (P29058), HMDH2_SOLLC (P48022), HMDH2_SOLTU (Q41437), HMDH2_YEAST (P12684), HMDH3_HEVBR (Q00583), HMDH3_ORYSJ (Q9XHL5), HMDH3_SOLTU (Q41438), HMDH_AGRIP (O76819), HMDH_ARCFU (O28538), HMDH_ASPTE (Q9Y7D2), HMDH_ASPTN (Q0C8L9), HMDH_BLAGE (P54960), HMDH_BOVIN (A7Z064), HMDH_CAMAC (P48021), HMDH_CANAL (A0A1D8PD39), HMDH_CATRO (Q03163), HMDH_CRIGR (P00347), HMDH_CYBJA (O74164), HMDH_DROME (P14773), HMDH_GANLU (B2KX91), HMDH_GIBF5 (S0DQM8), HMDH_GIBFU (P0CT44), HMDH_HUMAN (P04035), HMDH_MAIZE (O24594), HMDH_MESAU (P09610), HMDH_MOUSE (Q01237), HMDH_NICSY (Q01559), HMDH_PHYB8 (Q12649), HMDH_PIG(Q1W675), HMDH_PONAB (Q5R6N3), HMDH_RABIT (Q29512), HMDH_RAT(P51639), HMDH_SCHMA (P16237), HMDH_STRPU (P16393), HMDH_XENLA (P20715), HMGR1_PANGI (A0A0A1C3I2), HMR2A_PANGI (A0A0A1C930), HMR2B_PANGI (U5JCC6), MLCD_PENCI (Q8J0F4), MOKG_MONPI (Q3S2U3), MVAA_PSEMV (P13702), PBCC_EMENI (C8VN86)» more
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| UniProtKB/Swiss-Prot False negative sequences |
11 sequences
HMDH2_ASPFU (Q4WSY2), HMDH_AERPE (Q9YAS4), HMDH_BORBU (O51628), HMDH_HALS3 (B0R6J9), HMDH_HALVD (Q59468), HMDH_METJA (Q58116), HMDH_METTH (O26662), HMDH_PYRAB (Q9V1R3), HMDH_PYRHO (O59469), HMDH_SACS2 (O08424), HMDH_SCHPO (Q10283)» more |
| PDB [Detailed view] |
38 PDB
1DQ8; 1DQ9; 1DQA; 1HW8; 1HW9; 1HWI; 1HWJ; 1HWK; 1HWL; 1QAX; 1QAY; 1R31; 1R7I; 1T02; 2Q1L; 2Q6B; 2Q6C; 2R4F; 3BGL; 3CCT; 3CCW; 3CCZ; 3CD0; 3CD5; 3CD7; 3CDA; 3CDB; 4I4B; 4I56; 4I64; 4I6A; 4I6W; 4I6Y; 7ULI; 8ECG; 8GDN; 8SZ6; 8VLQ » more |