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Entry: PS01192

General information about the entry

Entry name [info] HMG_COA_REDUCTASE_3
Accession [info] PS01192
Entry type [info] PATTERN
Date [info] 01-NOV-1997 CREATED;
01-NOV-1997 DATA UPDATE;
13-FEB-2019 INFO UPDATE.
PROSITE Doc. [info] PDOC00064
Associated ProRule [info] PRU10003

Name and characterization of the entry

Description [info] Hydroxymethylglutaryl-coenzyme A reductases signature 3.
Pattern [info] 
A-[LIVM]-x-[STAN]-x(2)-[LI]-x-[KRNQ]-[GSA]-H-[LM]-x-[FYLH].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2019_02 which contains 559'228 sequence entries.


Total number of hits 48 in 48 different sequences
Number of true positive hits 48 in 48 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 10
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 82.76 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 10
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 48 sequences 

HMDH1_ARATH (P14891    ), HMDH1_DICDI (P34135    ), HMDH1_GOSHI (O64966    ), 

HMDH1_HEVBR (P29057    ), HMDH1_ORYSI (A2X8W3    ), HMDH1_ORYSJ (Q0DY59    ), 
HMDH1_SOLTU (P48020    ), HMDH1_YEAST (P12683    ), HMDH2_ARATH (P43256    ), 
HMDH2_CAPAN (Q9XEL8    ), HMDH2_DICDI (P34136    ), HMDH2_GOSHI (O64967    ), 
HMDH2_HEVBR (P29058    ), HMDH2_SOLLC (P48022    ), HMDH2_SOLTU (Q41437    ), 
HMDH2_YEAST (P12684    ), HMDH3_HEVBR (Q00583    ), HMDH3_ORYSJ (Q9XHL5    ), 
HMDH3_SOLTU (Q41438    ), HMDH_AGRIP  (O76819    ), HMDH_ARCFU  (O28538    ), 
HMDH_ASPTE  (Q9Y7D2    ), HMDH_ASPTN  (Q0C8L9    ), HMDH_BLAGE  (P54960    ), 
HMDH_BOVIN  (A7Z064    ), HMDH_CAMAC  (P48021    ), HMDH_CATRO  (Q03163    ), 
HMDH_CRIGR  (P00347    ), HMDH_CYBJA  (O74164    ), HMDH_DROME  (P14773    ), 
HMDH_GIBF5  (S0DQM8    ), HMDH_GIBFU  (P0CT44    ), HMDH_HUMAN  (P04035    ), 
HMDH_MAIZE  (O24594    ), HMDH_MESAU  (P09610    ), HMDH_MOUSE  (Q01237    ), 
HMDH_NICSY  (Q01559    ), HMDH_PHYB8  (Q12649    ), HMDH_PIG    (Q1W675    ), 
HMDH_PONAB  (Q5R6N3    ), HMDH_RABIT  (Q29512    ), HMDH_RAT    (P51639    ), 
HMDH_SCHMA  (P16237    ), HMDH_STRPU  (P16393    ), HMDH_XENLA  (P20715    ), 
MLCD_PENCI  (Q8J0F4    ), MOKG_MONPI  (Q3S2U3    ), MVAA_PSEMV  (P13702    )
» more

UniProtKB/Swiss-Prot
False negative sequences		 10 sequences 

HMDH_AERPE  (Q9YAS4    ), HMDH_BORBU  (O51628    ), HMDH_HALS3  (B0R6J9    ), 

HMDH_HALVD  (Q59468    ), HMDH_METJA  (Q58116    ), HMDH_METTH  (O26662    ), 
HMDH_PYRAB  (Q9V1R3    ), HMDH_PYRHO  (O59469    ), HMDH_SACS2  (O08424    ), 
HMDH_SCHPO  (Q10283    )
» more

PDB
[Detailed view]		 4 PDB

1DQA; 1QAX; 1QAY; 4I4B

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