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annotation rule: PRU10003

General rule information [?]

Accession PRU10003
Dates 16-OCT-2006 (Created)
22-NOV-2019 (Last updated, Version 5)
Data class Domain
Predictors PROSITE; PS01192; HMG_COA_REDUCTASE_3
Name Hydroxymethylglutaryl-coenzyme A reductases
Function Undefined.

Propagated annotation [?]


Description [?]

+ AltName: Full=Hydroxymethylglutaryl-CoA reductase; AltName: Full=NADPH; EC 1.1.1.34;

Comments [?]

Catalytic activity RHEA:15989: (R)-mevalonate + CoA + 2 NADP(+) = (3S)-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADPH
EC 1.1.1.34

Features [?]

From: PS01192
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     7     7       Proton donor        

Additional information [?]

Size range unlimited amino acids
Related rules None
Repeats 1
Topology Undefined
Example P00347 (HMDH_CRIGR)
Scope
Eukaryota
Bacteria
Archaea

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets
Archaea [9]
Bacteria [2]
Eukaryota [50]
All [ 61 ]