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| annotation rule: PRU10003 |
General rule information
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| Accession | PRU10003 |
| Dates | 16-OCT-2006 (Created) 22-NOV-2019 (Last updated, Version 5) |
| Data class | Domain |
| Predictors | PROSITE; PS01192; HMG_COA_REDUCTASE_3 |
| Name | Hydroxymethylglutaryl-coenzyme A reductases |
| Function | Undefined. |
Propagated annotation
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Description
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| + AltName: Full=Hydroxymethylglutaryl-CoA reductase; AltName: Full=NADPH; EC 1.1.1.34; |
Comments
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| Catalytic activity | RHEA:15989: (R)-mevalonate + CoA + 2 NADP(+) = (3S)-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADPH
EC 1.1.1.34 |
Features
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| From: PS01192 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 7 | 7 | Proton donor | |||||||||
Additional information
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| Size range | unlimited amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Undefined |
| Example | P00347 (HMDH_CRIGR) |
| Scope | Eukaryota
Bacteria
Archaea |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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