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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS01212


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PURL: https://purl.expasy.org/prosite/signature/PS01212

Direct ScanProsite submission
General information about the entry

Entry name [info] P2X_RECEPTOR
Accession [info] PS01212
Entry type [info] PATTERN
Date [info] 01-NOV-1997 CREATED;
01-NOV-1997 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00932

Name and characterization of the entry

Description [info] ATP P2X receptors signature.
Pattern [info]
G-G-x-[LIVM]-G-[LIVM]-x-[IV]-x-W-x-C-[DN]-L-D-x(5)-C-x-P-x-Y-x-F.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 24 in 24 different sequences
Number of true positive hits 24 in 24 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
24 sequences

P2RX1_HUMAN (P51575), P2RX1_MOUSE (P51576), P2RX1_RAT   (P47824), 
P2RX2_CAVPO (O70397), P2RX2_HUMAN (Q9UBL9), P2RX2_MOUSE (Q8K3P1), 
P2RX2_RAT   (P49653), P2RX3_HUMAN (P56373), P2RX3_MOUSE (Q3UR32), 
P2RX3_RAT   (P49654), P2RX4_BOVIN (Q5E9U1), P2RX4_HUMAN (Q99571), 
P2RX4_MOUSE (Q9JJX6), P2RX4_RAT   (P51577), P2RX5_HUMAN (Q93086), 
P2RX5_MOUSE (Q91VE2), P2RX5_RAT   (P51578), P2RX6_HUMAN (O15547), 
P2RX6_MOUSE (O54803), P2RX6_RAT   (P51579), P2RX7_HUMAN (Q99572), 
P2RX7_MOUSE (Q9Z1M0), P2RX7_RAT   (Q64663), P2X4A_DANRE (F8W463)
» more

PDB
[Detailed view]
39 PDB

pdb_00003h9v; pdb_00003i5d; pdb_00004dw0; pdb_00004dw1; pdb_00005svj; pdb_00005svk; pdb_00005svl; pdb_00005svm; pdb_00005svp; pdb_00005svq; pdb_00005svr; pdb_00005svs; pdb_00005svt; pdb_00005wzy; pdb_00005yve; pdb_00006ah4; pdb_00006ah5; pdb_00006u9v; pdb_00006u9w; pdb_00008jv5; pdb_00008jv6; pdb_00008tr5; pdb_00008tr6; pdb_00008tr7; pdb_00008tr8; pdb_00008tra; pdb_00008trb; pdb_00008trj; pdb_00008trk; pdb_00008v4s; pdb_00009b73; pdb_00009b95; pdb_00009bqh; pdb_00009bqi; pdb_00009c2a; pdb_00009c2b; pdb_00009c2c; pdb_00009c48; pdb_00009ik1
» more