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Entry: PS01226

General information about the entry

Entry name [info] HMG_COA_SYNTHASE
Accession [info] PS01226
Entry type [info] PATTERN
Date [info] 01-NOV-1997 CREATED;
01-NOV-1997 DATA UPDATE;
07-APR-2021 INFO UPDATE.
PROSITE Doc. [info] PDOC00942
Associated ProRule [info] PRU10116

Name and characterization of the entry

Description [info] Hydroxymethylglutaryl-coenzyme A synthase active site.
Pattern [info] 
N-x-[DN]-[IV]-E-G-[IV]-D-x(2)-N-A-C-[FY]-x-G.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2021_02 which contains 564'638 sequence entries.


Total number of hits 20 in 20 different sequences
Number of true positive hits 20 in 20 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 1
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 95.24 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] active_site at position 12
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 20 sequences 

AKT41_ALTAL (V5XYR2    ), HCS1_USTMA  (Q4P3F1    ), HCS1_ZYMTI  (F9X3D9    ), 

HMCS1_BLAGE (P54961    ), HMCS1_CHICK (P23228    ), HMCS1_CRIGR (P13704    ), 
HMCS1_HUMAN (Q01581    ), HMCS1_MOUSE (Q8JZK9    ), HMCS1_PONAB (Q5R7Z9    ), 
HMCS1_RAT   (P17425    ), HMCS2_BLAGE (P54870    ), HMCS2_BOVIN (Q2KIE6    ), 
HMCS2_HUMAN (P54868    ), HMCS2_MOUSE (P54869    ), HMCS2_PIG   (O02734    ), 
HMCS2_RAT   (P22791    ), HMCS_ARATH  (P54873    ), HMCS_CAEEL  (P54871    ), 
HMCS_SCHPO  (P54874    ), HMCS_YEAST  (P54839    )
» more

UniProtKB/Swiss-Prot
False negative sequences		 1 sequence 

HMCSA_DICDI (P54872    )


				
	

	

		PDB
[Detailed view]		
		
			2 PDB
			


			2P8U; 2WYA
				
	





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