PROSITE entry PS01226
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General information about the entry
| Entry name [info] | HMG_COA_SYNTHASE |
| Accession [info] | PS01226 |
| Entry type [info] | PATTERN |
| Date [info] |
01-NOV-1997 CREATED;
01-NOV-1997 DATA UPDATE; 03-MAY-2023 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00942 |
| Associated ProRule [info] | PRU10116 |
Name and characterization of the entry
| Description [info] | Hydroxymethylglutaryl-coenzyme A synthase active site. |
| Pattern [info] |
N-x-[DN]-[IV]-E-G-[IV]-D-x(2)-N-A-C-[FY]-x-G. |
Numerical results [info]
| Total number of hits | 24 in 24 different sequences |
| Number of true positive hits | 24 in 24 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 1 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 96.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Site [info] | active_site at position 12 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
24 sequences
AKT41_ALTAL (V5XYR2 ), ER13A_ASPFU (Q4WBQ3 ), ER13B_ASPFU (Q4WXT8 ), ERG13_CANAL (A0A1D8PTW6), ERG13_GIBZE (I1RY35 ), ERG13_SCHPO (P54874 ), ERG13_YEAST (P54839 ), HCS1_USTMA (Q4P3F1 ), HCS1_ZYMTI (F9X3D9 ), HMCS1_BLAGE (P54961 ), HMCS1_CHICK (P23228 ), HMCS1_CRIGR (P13704 ), HMCS1_HUMAN (Q01581 ), HMCS1_MOUSE (Q8JZK9 ), HMCS1_PONAB (Q5R7Z9 ), HMCS1_RAT (P17425 ), HMCS2_BLAGE (P54870 ), HMCS2_BOVIN (Q2KIE6 ), HMCS2_HUMAN (P54868 ), HMCS2_MOUSE (P54869 ), HMCS2_PIG (O02734 ), HMCS2_RAT (P22791 ), HMCS_ARATH (P54873 ), HMCS_CAEEL (P54871 )» more
|
| UniProtKB/Swiss-Prot False negative sequences |
1 sequence
HMCSA_DICDI (P54872 ) |
| PDB [Detailed view] |
2 PDB
2P8U; 2WYA |