ProRule PRU10116
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU10116 |
| Accession | PRU10116 |
| Dates | 16-OCT-2006 (Created)
14-OCT-2024 (Last updated, Version 6) |
| Data class | Domain; |
| Predictors |
PROSITE; PS01226; HMG_COA_SYNTHASE |
Name | Hydroxymethylglutaryl-coenzyme A synthase active site |
| Function | Undefined |
| Scope(s) |
Eukaryota |
| Example(s) | P23228 (HMCS1_CHICK); |
Propagated annotation
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Identifier, protein and gene names
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| Protein name | + AltName: Full=Hydroxymethylglutaryl-CoA synthase; EC=2.3.3.10; |
Comments
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| CATALYTIC ACTIVITY | Reaction=acetoacetyl-CoA + acetyl-CoA + H2O = (3S)-3-hydroxy-3- methylglutaryl-CoA + CoA + H(+); Xref=Rhea:RHEA:10188, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:43074, ChEBI:CHEBI:57286, ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=2.3.3.10; |
Features
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| From: PS01226 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 10 | 10 | ||||||||||
Additional information
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| Size range | unlimited amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
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UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [25] All [ 25 ]
- Retrieve set of proteins with 3D structure for this domain