Due to maintenance work, this service will be unavailable from
Mon Nov 11 17:30 until
Tue Nov 12 09:00
CET.
Apologies for the inconvenience.
ProRule PRU10116
General rule information
[?]
| Accession | PRU10116 |
| Dates | 16-OCT-2006 (Created)
22-NOV-2019 (Last updated, Version 5) |
| Data class | Domain; |
| Predictors |
PROSITE; PS01226; HMG_COA_SYNTHASE |
Name | Hydroxymethylglutaryl-coenzyme A synthase active site |
| Function | Undefined |
| Scope(s) |
Eukaryota |
| Example(s) | P23228 (HMCS1_CHICK); |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
| Protein name | + AltName: Full=Hydroxymethylglutaryl-CoA synthase; EC=2.3.3.10; |
Comments
[?]
| CATALYTIC ACTIVITY | Reaction=acetoacetyl-CoA + acetyl-CoA + H2O = (3S)-hydroxy-3- methylglutaryl-CoA + CoA + H(+); Xref=Rhea:RHEA:10188, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:43074, ChEBI:CHEBI:57286, ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=2.3.3.10; |
Features
[?]
| From: PS01226 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 10 | 10 | ||||||||||
Additional information
[?]
| Size range | unlimited amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
[?]
- UniProtKB/Swiss-Prot sets
Eukaryota [25] All [ 25 ]
- Retrieve set of proteins with 3D structure for this domain