PROSITE entry PS01240

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PURL: https://purl.expasy.org/prosite/signature/PS01240

Direct ScanProsite submission

General information about the entry

Entry name [info]	PNP_MTAP_2
Accession [info]	PS01240
Entry type [info]	PATTERN
Date [info]	01-NOV-1997 CREATED; 01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00954

Name and characterization of the entry

Description [info]	Purine and other phosphorylases family 2 signature.
Pattern [info]	[LIVF]-x(3)-[GS]-x(2)-H-x-[LIVMFY]-x(4)-[LIVMF]-x(3)-[ATV]-x(1,2)-[LIVM]- x-[ATV]-x(4)-[GN]-x(3,4)-[LIVMF](2)-x(2)-[STN]-[SAGT]-x-G-[GS]-[LIVM].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.

Total number of hits	72 in 72 different sequences
Number of true positive hits	72 in 72 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	23
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	75.79 %

Comments [info]

Taxonomic range [info]	Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

72 sequences

MTAP1_PUCGT (E3K7C3), MTAP2_PUCGT (E3K7C1), MTAP_AEDAE  (Q16MW6),

MTAP_AERPE  (Q9YAQ8), MTAP_AJECG  (C0NRX4), MTAP_ANODA  (E3XFR6), 
MTAP_ANOGA  (Q7Q9N9), MTAP_ASPFU  (Q4WMU1), MTAP_BOVIN  (Q3MHF7), 
MTAP_CAEBR  (A8XGS6), MTAP_CAEEL  (Q09438), MTAP_CANAL  (Q59ST1), 
MTAP_CANAW  (C4YQD9), MTAP_CENSY  (A0RVQ7), MTAP_CHLAA  (A9WAL0), 
MTAP_CIOIN  (F6X2V8), MTAP_COPC7  (A8P7Y3), MTAP_CRYNJ  (Q5KPU2), 
MTAP_DANRE  (Q7ZV22), MTAP_DROME  (Q9V813), MTAP_DROPS  (Q291H4), 
MTAP_EMENI  (C8VP37), MTAP_FUSV7  (C7YLQ3), MTAP_GLOVI  (Q7NHW1), 
MTAP_HUMAN  (Q13126), MTAP_HYPBU  (A2BIU4), MTAP_LEPIC  (Q72LZ4), 
MTAP_LEPIN  (Q8CXR2), MTAP_MACMU  (F6RQL9), MTAP_MOUSE  (Q9CQ65), 
MTAP_MYCMD  (Q4PH43), MTAP_NEMVE  (A7SN31), MTAP_NEUCR  (Q7RZA5), 
MTAP_NITMS  (A9A3N5), MTAP_PROMA  (Q7VDN6), MTAP_PYRAB  (Q9V2F1), 
MTAP_PYRFU  (Q8U4Q8), MTAP_PYRHO  (O57865), MTAP_RHORT  (Q2RXH9), 
MTAP_SACS2  (Q97W94), MTAP_SCHPO  (Q09816), MTAP_SCLS1  (A7EAA1), 
MTAP_THEAC  (Q9HL98), MTAP_THEKO  (Q5JEQ6), MTAP_THEPD  (A1RXU2), 
MTAP_TUBMM  (D5GFR0), MTAP_YARLI  (Q6CES3), MTAP_YEAST  (Q07938), 
MTIP_METJA  (Q60367), MTIP_PSEAE  (Q9HZK1), MTIP_PSESM  (Q87ZC3), 
MTIP_XANCP  (Q8PB40), MTIP_XYLFA  (Q9PAZ2), MTIP_XYLFT  (Q87BR7), 
PNPH_AQUAE  (O66839), PNPH_BOVIN  (P55859), PNPH_DICTD  (B8E181), 
PNPH_HUMAN  (P00491), PNPH_MOUSE  (P23492), PNPH_PYRFU  (Q8U2I1), 
PNPH_RAT(P85973), PNPH_THEKO  (Q5JJB8), PNPH_YEAST  (Q05788), 
PUNA_BACSU  (P46354), PUNA_CELSP  (P81989), PUNA_GEOSE  (P77834), 
PUNA_MYCBO  (P0A539), PUNA_MYCLE  (P46862), PUNA_MYCTO  (P9WP00), 
PUNA_MYCTU  (P9WP01), XAPA_ECOLI  (P45563), YPE2_RHORU  (P23139)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

23 sequences

MTAP_BRADU  (Q89VT5), MTAP_CERS4  (Q3J5E8), MTAP_GEOSL  (Q74E52),

MTAP_KORVE  (Q1INC3), MTAP_MYCS2  (A0QR54), MTAP_MYCTU  (O06401), 
MTAP_PHANO  (Q0U796), MTAP_PYRAE  (Q8ZTB2), MTAP_SYNY3  (P0DJF8), 
MTAP_SYNYG  (P0DJF9), MTAP_THEVB  (Q8DJE4), MTAP_XENTR  (F6V515), 
MTIP_METAC  (Q8TQX8), MTIP_METKA  (Q8TZB4), MTIP_METTH  (O27633), 
MTIP_THEYD  (B5YKP5), PNPH_ARCFU  (O28486), PNPH_DROME  (Q8IMU4), 
PNPH_DROPS  (Q297F5), PNPH_KORCO  (B1L719), PNPH_MOOTA  (Q2RKL6), 
PNPH_SCHPO  (Q9UTG1), PNPH_STRCO  (Q9KYV7)

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PDB
[Detailed view]

100 PDB

pdb_00001a9o; pdb_00001a9p; pdb_00001a9q; pdb_00001a9r; pdb_00001a9s; pdb_00001a9t; pdb_00001b8n; pdb_00001b8o; pdb_00001c3x; pdb_00001cb0; pdb_00001cg6; pdb_00001fxu; pdb_00001g2o; pdb_00001i80; pdb_00001k27; pdb_00001lv8; pdb_00001lvu; pdb_00001m73; pdb_00001n3i; pdb_00001pbn; pdb_00001pf7; pdb_00001pwy; pdb_00001qe5; pdb_00001rct; pdb_00001rfg; pdb_00001rr6; pdb_00001rsz; pdb_00001rt9; pdb_00001sd1; pdb_00001sd2; pdb_00001ula; pdb_00001ulb; pdb_00001v2h; pdb_00001v3q; pdb_00001v41; pdb_00001v45; pdb_00001v48; pdb_00001vfn; pdb_00001wta; pdb_00001yqq; pdb_00001yqu; pdb_00001yr3; pdb_00001yry; pdb_00002a0w; pdb_00002a0x; pdb_00002a0y; pdb_00002a8y; pdb_00002ai1; pdb_00002ai2; pdb_00002ai3; pdb_00002oc4; pdb_00002oc9; pdb_00002on6; pdb_00002q7o; pdb_00002qpl; pdb_00003bgs; pdb_00003d1v; pdb_00003fuc; pdb_00003gb9; pdb_00003ggs; pdb_00003iny; pdb_00003iom; pdb_00003ix2; pdb_00003k8o; pdb_00003k8q; pdb_00003ozb; pdb_00003ozc; pdb_00003ozd; pdb_00003oze; pdb_00003phb; pdb_00003pnp; pdb_00003scz; pdb_00003t94; pdb_00004ear; pdb_00004eb8; pdb_00004ece; pdb_00004gka; pdb_00004pnp; pdb_00005etj; pdb_00005eub; pdb_00005tc5; pdb_00005tc6; pdb_00005tc7; pdb_00005tc8; pdb_00005ugf; pdb_00006dyz; pdb_00006dz0; pdb_00006dz2; pdb_00006dz3; pdb_00007zsl; pdb_00007zsm; pdb_00007zsn; pdb_00007zso; pdb_00007zsp; pdb_00007zsq; pdb_00007zsr; pdb_00008c25; pdb_00008ws2; pdb_00009jd2; pdb_00009jhv
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