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PROSITE entry PS01252


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS01252
Entry name [info] OPIOIDS_PRECURSOR
Accession [info] PS01252
Entry type [info] PATTERN
Date [info] 01-NOV-1997 CREATED;
01-JUL-1999 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00964

Name and characterization of the entry

Description [info] Endogenous opioids neuropeptides precursors signature.
Pattern [info] 
C-x(3)-C-x(2)-C-x(2)-[KRH]-x(6,7)-[LIF]-[DNS]-x(3)-C-x-[LIVM]-[EQ]-C-
[EQ]-x(8)-W-x(2)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 17 in 17 different sequences
Number of true positive hits 17 in 17 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 1
Number of 'partial' sequences 3
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 94.44 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide(?) at position 1
Site [info] disulfide(?) at position 3
Site [info] disulfide(?) at position 5
Site [info] disulfide(?) at position 12
Site [info] disulfide(?) at position 16
Site [info] disulfide(?) at position 21
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 17 sequences 

PDYN_BOVIN  (Q95104), PDYN_CAVPO  (Q60478), PDYN_HUMAN  (P01213), 

PDYN_MOUSE  (O35417), PDYN_PIG(P01214), PDYN_RAT(P06300), 
PENKA_XENLA (P01212), PENK_BOVIN  (P01211), PENK_CAVPO  (P47969), 
PENK_HUMAN  (P01210), PENK_MESAU  (P50175), PENK_MOUSE  (P22005), 
PENK_RAT(P04094), PNOC_BOVIN  (O62647), PNOC_HUMAN  (Q13519), 
PNOC_MOUSE  (Q64387), PNOC_RAT(Q62923)
» more

UniProtKB/Swiss-Prot
False negative sequences		 1 sequence 

PENKV_MEIAT (P0DP56)


				
	

	

		UniProtKB/Swiss-Prot
'Partial' sequences		
		
			3 sequences
			


			
PENKB_XENLA (P07194), PENK_FELCA  (Q28409), PNOC_PIG(P55791)