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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
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Amos Bairoch

PROSITE entry PS01262


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PURL: https://purl.expasy.org/prosite/signature/PS01262

Direct ScanProsite submission
General information about the entry

Entry name [info] IF1A
Accession [info] PS01262
Entry type [info] PATTERN
Date [info] 01-NOV-1997 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00970

Name and characterization of the entry

Description [info] Eukaryotic initiation factor 1A signature.
Pattern [info] 
[IMVALH]-x-G-x-[GSDENK]-[KRHFW]-x(4)-[CL]-x-D-G-x(2)-[RY]-x(2)-[RH]-[IL]-
x-G.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 57 in 57 different sequences
Number of true positive hits 57 in 57 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 3
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 95.00 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 57 sequences 

IF1A1_HALSA (Q9HN64), IF1A1_HALWD (Q18EX1), IF1A1_METAC (Q8TSA3), 

IF1A1_METBF (Q469J2), IF1A1_METMA (Q8PVF1), IF1A2_HALSA (Q9HP87), 
IF1A2_HALWD (Q18JF4), IF1A2_METAC (Q8TR33), IF1A2_METBF (Q469I9), 
IF1A2_METMA (Q8PUJ8), IF1A3_METAC (Q8TR31), IF1AX_HUMAN (P47813), 
IF1AX_MOUSE (Q8BMJ3), IF1AX_PONAB (Q5RA42), IF1AY_HUMAN (O14602), 
IF1AY_PANTR (Q6GVM3), IF1A_AERPE  (P57676), IF1A_ARCFU  (O29481), 
IF1A_DICDI  (Q54YJ6), IF1A_HALMA  (Q5UZM2), IF1A_HALS3  (B0R7D8), 
IF1A_META3  (A6UUK8), IF1A_METBU  (Q12YN5), IF1A_METJA  (Q57887), 
IF1A_METKA  (Q8TXZ3), IF1A_METLZ  (A2STQ8), IF1A_METM5  (A4FYM5), 
IF1A_METM6  (A9A6C2), IF1A_METM7  (A6VJQ7), IF1A_METMP  (Q6LZM1), 
IF1A_METS5  (A4YEH8), IF1A_METTH  (O27085), IF1A_MOUSE  (Q60872), 
IF1A_NATPD  (Q3IT14), IF1A_ONOVI  (P56331), IF1A_PICTO  (Q6L2G4), 
IF1A_PYRAB  (Q9V138), IF1A_PYRAE  (Q8ZXV9), IF1A_PYRFU  (Q8U0K5), 
IF1A_PYRHO  (O59280), IF1A_RABIT  (P47814), IF1A_RAT(Q6VV72), 
IF1A_SACI1  (C3NMA0), IF1A_SACI2  (C3MK60), IF1A_SACI3  (C3N0P1), 
IF1A_SACI4  (C3MU29), IF1A_SACI6  (C4KK84), IF1A_SACI7  (C3N8M9), 
IF1A_SACS2  (Q97W62), IF1A_SCHPO  (P55877), IF1A_SULAC  (Q4JA54), 
IF1A_SULTO  (Q974Z9), IF1A_THEAC  (Q03590), IF1A_THEKO  (Q5JH78), 
IF1A_THEVO  (Q979F7), IF1A_WHEAT  (P47815), IF1A_YEAST  (P38912)
» more

UniProtKB/Swiss-Prot
False negative sequences		 3 sequences 

IF1A_DESA1  (B8D5N1), IF1A_METST  (Q2NEP1), YN98_SCHPO  (Q9Y803)


				
	

	

		PDB
[Detailed view]		
		
			59 PDB
			


			pdb_00001d7q; pdb_00001jt8; pdb_00003j80; pdb_00003j81; pdb_00003jam; pdb_00003jap; pdb_00003wbk; pdb_00003zjy; pdb_00004kzy; pdb_00004kzz; pdb_00004mno; pdb_00005jb3; 
			
				pdb_00005jbh; pdb_00006fyx; pdb_00006fyy; pdb_00006gsm; pdb_00006gsn; pdb_00006sw9; pdb_00006swc; pdb_00006swd; pdb_00006swe; pdb_00006ybw; pdb_00006zce; pdb_00006zmw; 
				pdb_00006zp4; pdb_00006zu9; pdb_00007a09; pdb_00007qp6; pdb_00007qp7; pdb_00007syq; pdb_00007syr; pdb_00007sys; pdb_00007syv; pdb_00007syw; pdb_00007syx; pdb_00007tql; 
				pdb_00007zag; pdb_00007zah; pdb_00007zai; pdb_00007zki; pdb_00008cah; pdb_00008cas; pdb_00008oz0; pdb_00008pj1; pdb_00008pj2; pdb_00008pj3; pdb_00008pj4; pdb_00008pj5; 
				pdb_00008pj6; pdb_00008ppl; pdb_00008rw1; pdb_00008s8d; pdb_00008s8e; pdb_00008s8f; pdb_00008s8g; pdb_00008s8h; pdb_00008s8i; pdb_00008s8j; pdb_00008s8k
			
			

			» more