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PROSITE entry PS01279


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS01279
Entry name [info] PCMT
Accession [info] PS01279
Entry type [info] PATTERN
Date [info] 01-NOV-1997 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00985

Name and characterization of the entry

Description [info] Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature.
Pattern [info] 
[GSAED]-[DN]-G-x(2)-G-[FYWLV]-x(3)-[GSA]-[PTL]-[FY]-[DNSHE]-x-I.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 296 in 296 different sequences
Number of true positive hits 295 in 295 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 45
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 99.66 %
Recall (true positives / (true positives + false negatives)) 86.76 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 295 sequences 

PIMT1_ARATH (Q42539), PIMT1_ARCFU (O30199), PIMT1_CUPNH (Q0KB67), 

PIMT1_GEOUR (A5GEF7), PIMT1_MARN8 (A1TZ54), PIMT1_METAC (Q8TT93), 
PIMT1_NITMU (Q2YCR1), PIMT1_RHOP2 (Q2J302), PIMT1_SHESH (A8FST4), 
PIMT1_SYNFM (A0LL58), PIMT2_ARATH (Q64J17), PIMT2_ARCFU (O27962), 
PIMT2_CUPNH (Q0K951), PIMT2_GEOUR (A5G4S7), PIMT2_MARN8 (A1U4P7), 
PIMT2_METAC (Q8TT94), PIMT2_NITMU (Q2YBR7), PIMT2_NITOC (Q3JAW6), 
PIMT2_PELPD (A1ASW6), PIMT2_POLSJ (Q123X2), PIMT2_SHESH (A8FX24), 
PIMT2_SYNFM (A0LM89), PIMT_AERHH  (A0KGH9), PIMT_AERPE  (Q9YDA1), 
PIMT_AERS4  (A4SRB5), PIMT_ALCBS  (Q0VQD1), PIMT_ALIF1  (Q5E332), 
PIMT_ALIFM  (B5FAF3), PIMT_ALISL  (B6EKL2), PIMT_ALTMD  (B4RZG8), 
PIMT_ANAD2  (B8J9E3), PIMT_ANADE  (Q2IIL9), PIMT_AROAE  (Q5P833), 
PIMT_AZOC5  (A8I4G3), PIMT_AZOSB  (A1K4F0), PIMT_BORA1  (Q2L008), 
PIMT_BORBR  (Q7WI37), PIMT_BORPA  (Q7W671), PIMT_BORPD  (A9IP04), 
PIMT_BOVIN  (P15246), PIMT_BRUA4  (A6X6Y1), PIMT_BURA4  (B1YRE4), 
PIMT_BURCH  (A0K7U6), PIMT_BURCM  (Q0BEV7), PIMT_BURL3  (Q39FP9), 
PIMT_BURM7  (A3MK86), PIMT_BURM9  (A2S291), PIMT_BURMA  (Q62JV3), 
PIMT_BURMS  (A1V4L2), PIMT_BURO0  (B1JTA2), PIMT_BURO1  (Q1BGY4), 
PIMT_BURP0  (A3NVY1), PIMT_BURP1  (Q3JRP1), PIMT_BURP6  (A3NA64), 
PIMT_BURPS  (Q63UU3), PIMT_BURTA  (Q2SWF4), PIMT_BURVG  (A4JEQ0), 
PIMT_CAEEL  (Q27873), PIMT_CAUSK  (B0T1Q1), PIMT_CAUVC  (Q9A6T6), 
PIMT_CAUVN  (B8GX51), PIMT_CERS1  (A3PIZ8), PIMT_CERS4  (Q3J3D1), 
PIMT_CERS5  (A4WU05), PIMT_CERSK  (B9KQZ1), PIMT_CHICK  (Q5F3N1), 
PIMT_CHLL2  (B3EEX3), PIMT_CHLP8  (B3QQM1), PIMT_CHLPB  (B3ELJ9), 
PIMT_CHLPD  (A1BDC1), PIMT_CHLPM  (A4SGH4), PIMT_CHLTE  (Q8KFW8), 
PIMT_CHRSD  (Q1QU77), PIMT_CHRVO  (Q7NRV0), PIMT_CITK8  (A8ANV7), 
PIMT_COLP3  (Q487E5), PIMT_CROS8  (A7MJ61), PIMT_CUPPJ  (Q46ZH2), 
PIMT_CYTH3  (Q11TS0), PIMT_DANRE  (Q92047), PIMT_DECAR  (Q47D25), 
PIMT_DESOH  (A8ZXR8), PIMT_DESPS  (Q6ARM1), PIMT_DICT6  (B5YF00), 
PIMT_DICTD  (B8E0T1), PIMT_DINSH  (A8LQK6), PIMT_DROME  (Q27869), 
PIMT_ECO24  (A7ZQI7), PIMT_ECO27  (B7UHG2), PIMT_ECO45  (B7MKL7), 
PIMT_ECO55  (B7LEG1), PIMT_ECO57  (P0A7A6), PIMT_ECO5E  (B5Z3A5), 
PIMT_ECO7I  (B7NT87), PIMT_ECO81  (B7MZ44), PIMT_ECO8A  (B7LXF5), 
PIMT_ECOBW  (C4ZZP7), PIMT_ECODH  (B1XCR9), PIMT_ECOHS  (A8A3M2), 
PIMT_ECOK1  (A1AET7), PIMT_ECOL6  (Q8FEJ8), PIMT_ECOLC  (B1IUT6), 
PIMT_ECOLI  (P0A7A5), PIMT_ECOLU  (B7N6X3), PIMT_ECOSE  (B6I6D3), 
PIMT_ECOSM  (B1LQ63), PIMT_ECOUT  (Q1R7U8), PIMT_ECTM1  (A4XWR1), 
PIMT_ENT38  (A4WDU8), PIMT_ERWT9  (B2VG25), PIMT_ESCF3  (B7LWJ2), 
PIMT_FERNB  (A7HL14), PIMT_FLAJ1  (A5FEA5), PIMT_FLAPJ  (A6H0V1), 
PIMT_GEOMG  (Q39VS0), PIMT_GEOSL  (Q74CZ5), PIMT_GLOVI  (Q7NJY2), 
PIMT_HAHCH  (Q2SKW3), PIMT_HALHL  (A1WWY5), PIMT_HELP2  (B6JMT1), 
PIMT_HELPG  (B5Z887), PIMT_HELPJ  (Q9ZKC2), PIMT_HELPY  (P56133), 
PIMT_HERA2  (A9AUP1), PIMT_HERAR  (A4G4J3), PIMT_HUMAN  (P22061), 
PIMT_HYPBU  (A2BKH8), PIMT_IDILO  (Q5QUB2), PIMT_IGNH4  (A8AAV7), 
PIMT_JANMA  (A6SZX9), PIMT_KLEP3  (B5XV38), PIMT_KLEP7  (A6TD35), 
PIMT_KORVE  (Q1INS6), PIMT_LAWIP  (Q1MRE5), PIMT_MACFA  (Q4R5H0), 
PIMT_MARMM  (Q0ANE2), PIMT_MARSD  (C6BTT9), PIMT_METB6  (A7I4W9), 
PIMT_METBU  (Q12UV0), PIMT_METEP  (A9VY77), PIMT_METFK  (Q1H095), 
PIMT_METJA  (Q57636), PIMT_METKA  (Q8TYL4), PIMT_METM5  (A4G087), 
PIMT_METM6  (A9A8I9), PIMT_METM7  (A6VI91), PIMT_METMA  (Q8PW90), 
PIMT_METMJ  (A3CXP8), PIMT_METMP  (Q6M116), PIMT_METPB  (B1ZJW1), 
PIMT_METTH  (O26915), PIMT_METTP  (A0B9U1), PIMT_MOUSE  (P23506), 
PIMT_MYXXD  (Q1D6W9), PIMT_NITEC  (Q0ADP2), PIMT_NITEU  (Q82VW0), 
PIMT_NITV2  (Q72AZ1), PIMT_NITV4  (A1VD15), PIMT_NITV9  (B8DJP7), 
PIMT_OLEA2  (Q30ZM2), PIMT_OPITP  (B1ZPF0), PIMT_PARDP  (A1B5M0), 
PIMT_PARL1  (A7HXK6), PIMT_PARM1  (Q2W4A2), PIMT_PARP8  (B2JG67), 
PIMT_PARUW  (Q6MCW9), PIMT_PECAS  (Q6D1B6), PIMT_PECCP  (C6DDF9), 
PIMT_PELPB  (B4SFU3), PIMT_PELTS  (A5CYQ6), PIMT_PHOLL  (Q7N8K3), 
PIMT_PHOPR  (Q6LMT7), PIMT_PICP2  (B1XQE1), PIMT_PIG(P80895), 
PIMT_PONAB  (Q5RA89), PIMT_PROMH  (B4F223), PIMT_PSE14  (Q48F88), 
PIMT_PSEA6  (Q15P27), PIMT_PSEA7  (A6V1G4), PIMT_PSEA8  (B7V8C3), 
PIMT_PSEAB  (Q02R96), PIMT_PSEAE  (P45683), PIMT_PSEE4  (Q1I655), 
PIMT_PSEF5  (Q4KHE7), PIMT_PSEFS  (C3K706), PIMT_PSEP1  (A5W820), 
PIMT_PSEPF  (Q3KH83), PIMT_PSEPG  (B0KSC8), PIMT_PSEPK  (Q88MF0), 
PIMT_PSEPW  (B1JB29), PIMT_PSESM  (Q886L4), PIMT_PSET1  (Q3IDD2), 
PIMT_PSEU2  (Q4ZWP9), PIMT_PYRAB  (Q9UXX0), PIMT_PYRAE  (Q8ZYN0), 
PIMT_PYRAR  (A4WNC5), PIMT_PYRFU  (Q8TZR3), PIMT_PYRHO  (O59534), 
PIMT_PYRIL  (A1RSC6), PIMT_PYRNV  (B1YC47), PIMT_RALN1  (Q8Y039), 
PIMT_RAT(P22062), PIMT_RHIME  (O08249), PIMT_RHOCS  (B6ISM3), 
PIMT_RHOPA  (Q6NCU3), PIMT_RHORT  (Q2RTH7), PIMT_ROSCS  (A7NI01), 
PIMT_ROSDO  (Q163U2), PIMT_ROSS1  (A5UZW2), PIMT_RUEPO  (Q5LQ09), 
PIMT_SACD2  (Q21LB7), PIMT_SALA4  (B5F407), PIMT_SALAR  (A9MF32), 
PIMT_SALCH  (Q57KJ8), PIMT_SALDC  (B5FTS1), PIMT_SALEP  (B5QW14), 
PIMT_SALG2  (B5RDP9), PIMT_SALHS  (B4TFW3), PIMT_SALNS  (B4T453), 
PIMT_SALPA  (Q5PEE9), PIMT_SALPB  (A9N1H6), PIMT_SALPC  (C0PXA3), 
PIMT_SALPK  (B5BEY0), PIMT_SALRD  (Q2S176), PIMT_SALSV  (B4TTV7), 
PIMT_SALTI  (Q8Z474), PIMT_SALTY  (Q8ZMF9), PIMT_SERP5  (A8G9Z6), 
PIMT_SHEAM  (A1S4E3), PIMT_SHEB2  (B8E8T7), PIMT_SHEB5  (A3D789), 
PIMT_SHEB8  (A6WR22), PIMT_SHEB9  (A9KYG4), PIMT_SHEDO  (Q12PY8), 
PIMT_SHEFN  (Q086A4), PIMT_SHEHH  (B0TK10), PIMT_SHELP  (A3QC83), 
PIMT_SHEON  (Q8EBR6), PIMT_SHEPA  (A8H1T1), PIMT_SHEPC  (A4Y937), 
PIMT_SHEPW  (B8CJQ2), PIMT_SHESA  (A0KU88), PIMT_SHESM  (Q0HL66), 
PIMT_SHESR  (Q0HXG4), PIMT_SHESW  (A1RHF9), PIMT_SHEWM  (B1KPT0), 
PIMT_SHIB3  (B2TZI8), PIMT_SHIBS  (Q31XA5), PIMT_SHIDS  (Q32CI7), 
PIMT_SHIF8  (Q0T1H4), PIMT_SHIFL  (Q83JY3), PIMT_SHISS  (Q3YYB9), 
PIMT_SODGM  (Q2NVM1), PIMT_STAMF  (A3DMG3), PIMT_STRM5  (B4SR93), 
PIMT_STRMK  (B2FK95), PIMT_STUS1  (A4VJV3), PIMT_SYNAS  (Q2LUT4), 
PIMT_SYNJB  (Q2JJN4), PIMT_THEM4  (A6LNM3), PIMT_THEMA  (Q56308), 
PIMT_THEON  (B6YX51), PIMT_THESM  (C6A3F2), PIMT_TRIL1  (B3E6I4), 
PIMT_VIBA3  (B7VK62), PIMT_VIBC1  (A7MTT6), PIMT_VIBC3  (A5F9C1), 
PIMT_VIBCH  (Q9KUI8), PIMT_VIBCM  (C3LS22), PIMT_VIBPA  (Q87LQ6), 
PIMT_VIBVU  (Q8DC56), PIMT_VIBVY  (Q7MHQ8), PIMT_WHEAT  (Q43209), 
PIMT_XANAC  (Q8PLR3), PIMT_XANC8  (Q4UTP9), PIMT_XANCB  (B0RTZ8), 
PIMT_XANCP  (Q8P9Y6), PIMT_XANE5  (Q3BUS3), PIMT_XANOM  (Q2P1L5), 
PIMT_XANOP  (B2SUB3), PIMT_XANOR  (Q5GYL2), PIMT_XYLF2  (B2I8X8), 
PIMT_XYLFA  (Q9PF21), PIMT_XYLFM  (B0U4U6), PIMT_XYLFT  (Q87AK5), 
PIMT_YERE8  (A1JJT8), PIMT_YERP3  (A7FLX4), PIMT_YERPA  (Q1C474), 
PIMT_YERPB  (B2K581), PIMT_YERPE  (Q8ZBQ0), PIMT_YERPG  (A9R115), 
PIMT_YERPN  (Q1CLR2), PIMT_YERPP  (A4TQ01), PIMT_YERPS  (Q66EB9), 
PIMT_YERPY  (B1JJF4)
» more

UniProtKB/Swiss-Prot
False negative sequences		 45 sequences 

PCMD1_BOVIN (A2VDP2), PCMD1_CHICK (Q5ZMR3), PCMD1_HUMAN (Q96MG8), 

PCMD1_MOUSE (P59913), PCMD1_PONAB (Q5R7E5), PCMD2_HUMAN (Q9NV79), 
PCMD2_MOUSE (Q8BHD8), PCMD2_PONAB (Q5R7K4), PIMT1_ANADF (A7HC32), 
PIMT1_NITOC (Q3JCZ3), PIMT1_PELPD (A1ASL8), PIMT1_POLSJ (Q12A85), 
PIMT2_ANADF (A7HHV3), PIMT2_RHOP2 (Q2IWH1), PIMT3_GEOUR (A5G6S0), 
PIMT_AFIC5  (B6JFP0), PIMT_ALKEH  (Q0A7L5), PIMT_BRASB  (A5EJV5), 
PIMT_BRASO  (A4YV66), PIMT_CELJU  (B3PJA8), PIMT_CHLL3  (Q3B1L6), 
PIMT_CHRFK  (A0LZ51), PIMT_DESDA  (B8J017), PIMT_DICDI  (Q9GPS6), 
PIMT_JANSC  (Q28TH8), PIMT_KORCO  (B1L6T9), PIMT_LEPCP  (B1Y0T0), 
PIMT_MAGMM  (A0L4K5), PIMT_META3  (A6UWM1), PIMT_METAR  (Q0W2W0), 
PIMT_METHJ  (Q2FRW3), PIMT_METPP  (A2SF76), PIMT_METVS  (A6UR90), 
PIMT_NATTJ  (B2A578), PIMT_NITWN  (Q3SRQ7), PIMT_PETMO  (A9BH07), 
PIMT_PYRCJ  (A3MY16), PIMT_RHOP5  (Q07N42), PIMT_RHOPB  (Q214W4), 
PIMT_RHOPS  (Q136H9), PIMT_RUEST  (Q1GFP1), PIMT_SCHPO  (Q9URZ1), 
PIMT_SYNC1  (Q3A4N4), PIMT_THIDA  (Q3SKJ2), PIMT_XANP2  (A7INP1)
» more

UniProtKB/Swiss-Prot
False positive sequences		 1 sequence 

CSPL2_PICSI (A9NTU2)


				
	

	

		PDB
[Detailed view]		
		
			12 PDB
			


			1DL5; 1I1N; 1JG1; 1JG2; 1JG3; 1JG4; 1KR5; 1R18; 2YXE; 3LBF; 4L7V; 4O29