PROSITE entry PS01283

View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
PURL: https://purl.expasy.org/prosite/signature/PS01283

Direct ScanProsite submission

General information about the entry

Entry name [info]	TBOX_1
Accession [info]	PS01283
Entry type [info]	PATTERN
Date [info]	01-NOV-1997 CREATED; 01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00972

Name and characterization of the entry

Description [info]	T-box domain signature 1.
Pattern [info]	[LQI]-W-x(2)-[FCL]-x(3,4)-[NT]-E-[MQ]-[LIVNM]-[LIV]-[TLF]-x(2)-[GR]-[RG]- [KRQM].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.

Total number of hits	93 in 93 different sequences
Number of true positive hits	93 in 93 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	11
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	89.42 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

93 sequences

BRC2_HALRO  (O01409), BYN_DROME   (P55965), EOMES_HUMAN (O95936),

EOMES_MOUSE (O54839), EOMES_XENLA (P79944), H15_DROME   (Q94890), 
OMB_DROME   (Q24432), TBR1_HUMAN  (Q16650), TBR1_MOUSE  (Q64336), 
TBR1_PATPE  (Q9NL40), TBX10_HUMAN (O75333), TBX10_MOUSE (Q810F8), 
TBX11_CAEEL (Q20257), TBX12_CAEEL (P90971), TBX15_HUMAN (Q96SF7), 
TBX15_MOUSE (O70306), TBX18_CAEEL (O02073), TBX18_HUMAN (O95935), 
TBX18_MOUSE (Q9EPZ6), TBX19_CANLF (Q5XNS0), TBX19_CHICK (P79778), 
TBX19_HUMAN (O60806), TBX19_MOUSE (Q99ME7), TBX1A_XENLA (Q8AX98), 
TBX1B_XENLA (Q32NI9), TBX1_CAEEL  (O17212), TBX1_DANRE  (Q8AXX2), 
TBX1_HUMAN  (O43435), TBX1_MOUSE  (P70323), TBX1_XENTR  (Q3SA49), 
TBX20_CHICK (Q8UW76), TBX20_DANRE (Q9I9K7), TBX20_HUMAN (Q9UMR3), 
TBX20_MOUSE (Q9ES03), TBX20_XENLA (Q8AXW8), TBX20_XENTR (Q3SA46), 
TBX21_HUMAN (Q9UL17), TBX21_MOUSE (Q9JKD8), TBX22_HUMAN (Q9Y458), 
TBX22_MOUSE (Q8K402), TBX2A_XENLA (Q9IBC8), TBX2B_XENLA (Q6PCL0), 
TBX2_CAEEL  (Q19691), TBX2_CANLF  (Q863A2), TBX2_DANRE  (Q7ZTU9), 
TBX2_HUMAN  (Q13207), TBX2_MOUSE  (Q60707), TBX2_XENTR  (Q3SA48), 
TBX33_CAEEL (O45291), TBX37_CAEEL (Q9U2C9), TBX38_CAEEL (Q9XVD5), 
TBX3_CHICK  (O73718), TBX3_HUMAN  (O15119), TBX3_MOUSE  (P70324), 
TBX3_RAT(Q7TST9), TBX4_CANLF  (Q861Q9), TBX4_HUMAN  (P57082), 
TBX4_MOUSE  (P70325), TBX5A_DANRE (Q9IAK8), TBX5_CHICK  (Q9PWE8), 
TBX5_HUMAN  (Q99593), TBX5_MOUSE  (P70326), TBX5_RAT(Q5I2P1), 
TBX5_XENLA  (Q9W7C2), TBX5_XENTR  (Q3SA47), TBX6L_CHICK (P79779), 
TBX6L_DANRE (P79742), TBX6_BOVIN  (E1BEA8), TBX6_DANRE  (Q8JIS6), 
TBX6_GORGO  (A1YF56), TBX6_HUMAN  (O95947), TBX6_MOUSE  (P70327), 
TBX6_RAT(D3ZJK7), TBX6_XENLA  (Q8AV66), TBX6_XENTR  (Q66JL1), 
TBX7_CAEEL  (Q95PX3), TBX8_CAEEL  (Q22292), TBX9_CAEEL  (Q22289), 
TBXT1_BRAFL (Q17134), TBXT2_BRAFL (P80492), TBXTA_DANRE (Q07998), 
TBXT_CANLF  (Q9GL27), TBXT_CHICK  (P79777), TBXT_HALRO  (P56158), 
TBXT_HEMPU  (Q25113), TBXT_HUMAN  (O15178), TBXT_MOUSE  (P20293), 
TBXT_PATPE  (Q9U903), TBXT_XENLA  (P24781), VEGTA_XENLA (P87377), 
VEGTB_XENLA (O13161), VEGT_XENBO  (Q98UD2), VEGT_XENTR  (Q28HY0)

» more

Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

11 sequences

MGAP_HUMAN  (Q8IWI9), MGAP_MOUSE  (A2AWL7), TBX30_CAEEL (Q9N2K7),

TBX31_CAEEL (Q9TZL0), TBX32_CAEEL (O61764), TBX34_CAEEL (Q9NAH2), 
TBX35_CAEEL (Q09376), TBX36_CAEEL (Q23622), TBX39_CAEEL (Q9NA56), 
TBX40_CAEEL (Q9NA55), TBX41_CAEEL (Q22813)

» more

PDB
[Detailed view]

65 PDB

pdb_00001h6f; pdb_00001xbr; pdb_00002x6u; pdb_00002x6v; pdb_00004a04; pdb_00004s0h; pdb_00005bqd; pdb_00005flv; pdb_00005qrf; pdb_00005qrg; pdb_00005qrh; pdb_00005qri; pdb_00005qrj; pdb_00005qrk; pdb_00005qrl; pdb_00005qrm; pdb_00005qrn; pdb_00005qro; pdb_00005qrp; pdb_00005qrq; pdb_00005qrr; pdb_00005qrs; pdb_00005qrt; pdb_00005qru; pdb_00005qrv; pdb_00005qrw; pdb_00005qrx; pdb_00005qry; pdb_00005qrz; pdb_00005qs0; pdb_00005qs1; pdb_00005qs2; pdb_00005qs3; pdb_00005qs4; pdb_00005qs5; pdb_00005qs6; pdb_00005qs7; pdb_00005qs8; pdb_00005qs9; pdb_00005qsa; pdb_00005qsb; pdb_00005qsc; pdb_00005qsd; pdb_00005qse; pdb_00005qsf; pdb_00005qsg; pdb_00005qsh; pdb_00005qsi; pdb_00005qsj; pdb_00005qsk; pdb_00005qsl; pdb_00005qt0; pdb_00005t1j; pdb_00006f58; pdb_00006f59; pdb_00006zu8; pdb_00007hi8; pdb_00007hi9; pdb_00007zk2; pdb_00007zkf; pdb_00007zl2; pdb_00008a10; pdb_00008a7n; pdb_00008cdn; pdb_00008fmu
» more