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PROSITE entry PS01333


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General information about the entry

Entry name [info] PYRASE_GLU
Accession [info] PS01333
Entry type [info] PATTERN
Date [info] 01-JUL-1999 CREATED;
01-DEC-2001 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC01036
Associated ProRule [info] PRU10076

Name and characterization of the entry

Description [info] Pyrrolidone-carboxylate peptidase glutamic acid active site.
Pattern [info]
G-x(2)-[GAP]-x(4)-[LIV]-[ST]-x-E-[KR]-[LIVC]-[AG]-x-[NG].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 136 in 136 different sequences
Number of true positive hits 135 in 135 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 16
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 99.26 %
Recall (true positives / (true positives + false negatives)) 89.40 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 8
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
135 sequences

PCP1_CALS4  (Q8RBX8), PCP1_PHOLL  (Q7MAZ1), PCP1_SACS2  (P58201), 
PCP1_STRPN  (P65678), PCP1_STRR6  (P65679), PCP2_CALS4  (Q8R9J6), 
PCP2_PHOLL  (Q7MZ76), PCP2_SACS2  (P58202), PCP_ALKOO   (A8MJA9), 
PCP_BACAA   (C3P0R7), PCP_BACAC   (C3LDV2), PCP_BACAH   (A0RFP3), 
PCP_BACAM   (P46107), PCP_BACAN   (Q81NT5), PCP_BACC0   (B7JDC3), 
PCP_BACC1   (Q735N6), PCP_BACC2   (B7IMH6), PCP_BACC3   (C1F026), 
PCP_BACC4   (B7H8H3), PCP_BACC7   (B7HVU3), PCP_BACCN   (A7GQB6), 
PCP_BACCQ   (B9J587), PCP_BACCR   (Q81BT3), PCP_BACCZ   (Q639M5), 
PCP_BACHK   (Q6HH08), PCP_BACLD   (Q65FR5), PCP_BACMK   (A9VKA7), 
PCP_BACSU   (P28618), PCP_BACVZ   (A7Z119), PCP_BRAHW   (C0QXM0), 
PCP_CITK8   (A8AJA6), PCP_CLOBA   (B2UZU4), PCP_CLOBB   (B2TK93), 
PCP_CLOD6   (Q186N3), PCP_CLOP1   (Q0TQH4), PCP_CLOPE   (Q8XKH1), 
PCP_CLOPS   (Q0ST25), PCP_COPPD   (B5Y5X6), PCP_DEIRA   (Q9RX25), 
PCP_ENT38   (A4W870), PCP_ENTFA   (Q838N8), PCP_ESCF3   (B7LKQ5), 
PCP_FINM2   (B0S415), PCP_FUSNN   (Q8RI83), PCP_GLOVI   (Q7NHX6), 
PCP_HALH5   (Q9K6U4), PCP_KLEP3   (B5XZE0), PCP_LACAC   (Q5FMJ2), 
PCP_LACCB   (B3W7M8), PCP_LACGA   (Q040L6), PCP_LACH4   (A8YX24), 
PCP_LACJO   (Q74HE9), PCP_LACLM   (O87765), PCP_LACP3   (Q03CK3), 
PCP_LEVBA   (Q03P20), PCP_LYSSC   (B1HUY7), PCP_MYCBO   (P0A5R5), 
PCP_MYCBP   (A1KFE2), PCP_MYCBT   (C1AJZ7), PCP_MYCMM   (B2HP18), 
PCP_MYCTA   (A5TZ46), PCP_MYCTO   (P9WIJ4), PCP_MYCTU   (P9WIJ5), 
PCP_OCEIH   (Q8ENE4), PCP_PECAS   (Q6D7H1), PCP_PECCP   (C6DCC7), 
PCP_PSEFL   (P42673), PCP_PSEFS   (C3JZR3), PCP_PYRAB   (Q9UYQ9), 
PCP_PYRFU   (O73944), PCP_PYRHO   (O58321), PCP_STAA1   (A7X782), 
PCP_STAA2   (A6U575), PCP_STAA3   (Q2FDH1), PCP_STAA8   (Q2FUS6), 
PCP_STAA9   (A5IWB7), PCP_STAAB   (Q2YZA2), PCP_STAAC   (Q5HCK7), 
PCP_STAAE   (A6QKH8), PCP_STAAM   (P65676), PCP_STAAN   (P65677), 
PCP_STAAR   (Q6GDB4), PCP_STAAS   (Q6G5Y4), PCP_STAAT   (A8Z5J1), 
PCP_STAAU   (Q53596), PCP_STAAW   (Q8NUH2), PCP_STACT   (B9DND6), 
PCP_STAHJ   (Q4L9S3), PCP_STAS1   (Q4A002), PCP_STRCO   (Q9RL48), 
PCP_STRP1   (P68896), PCP_STRP2   (Q04L55), PCP_STRP3   (P0DC94), 
PCP_STRP6   (Q5XDD4), PCP_STRP7   (C1C6J3), PCP_STRP8   (Q8P243), 
PCP_STRPB   (Q1JD20), PCP_STRPC   (Q1JMZ5), PCP_STRPD   (Q1JI40), 
PCP_STRPF   (Q1J7Y1), PCP_STRPG   (A2RFZ5), PCP_STRPI   (B1IB28), 
PCP_STRPM   (Q48UT7), PCP_STRPQ   (P0DC95), PCP_STRPZ   (B5XK96), 
PCP_STRS2   (A4W0R4), PCP_STRSY   (A4VUH1), PCP_SULIA   (C3N2L8), 
PCP_SULIK   (C4KEG7), PCP_SULIL   (C3MP49), PCP_SULIN   (C3NL04), 
PCP_SULIY   (C3NAL6), PCP_THEAB   (B7IEE2), PCP_THEKO   (Q5JEL5), 
PCP_THELN   (O07883), PCP_THEM4   (A6LL24), PCP_THEON   (B6YUJ5), 
PCP_THEP3   (B0K8Z7), PCP_THEPX   (B0K0D9), PCP_TREDE   (Q73RB6), 
PCP_VIBC1   (A7N3R7), PCP_VIBPA   (Q87IL9), PCP_YERE8   (A1JR34), 
PCP_YERP3   (A7FFS3), PCP_YERPA   (Q1C571), PCP_YERPB   (B2KA64), 
PCP_YERPE   (Q8ZD86), PCP_YERPG   (A9R3Y5), PCP_YERPN   (Q1CKF9), 
PCP_YERPP   (A4TKZ3), PCP_YERPS   (Q667T6), PCP_YERPY   (B1JRB0), 
PGPI_HUMAN  (Q9NXJ5), PGPI_MOUSE  (Q9ESW8), PGPI_RAT(Q76IC5)
» more

UniProtKB/Swiss-Prot
False negative sequences
16 sequences

PCP1_RALN1  (Q8XXE9), PCP2_RALN1  (Q8XT56), PCP2_STRPN  (Q97NG9), 
PCP_ALIF1   (Q5E531), PCP_ALIFM   (B5FEA5), PCP_BREBN   (C0ZCX0), 
PCP_CHRVO   (Q7NT84), PCP_CLAM3   (A5CM68), PCP_CUPNH   (Q0KFE0), 
PCP_CUPPJ   (Q477F9), PCP_CUPTR   (B2AG45), PCP_ERWT9   (B2VBP1), 
PCP_VIBVU   (Q8D4N5), PCP_VIBVY   (Q7MG84), PGPIL_HUMAN (A6NFU8), 
PGPIL_MOUSE (Q9CWB5)
» more

UniProtKB/Swiss-Prot
False positive sequences
1 sequence

HIS6_COREF  (Q8FNZ9)

		
PDB
[Detailed view]
19 PDB

1A2Z; 1AUG; 1IOF; 1IOI; 1IU8; 1X10; 1X12; 1Z8T; 1Z8W; 1Z8X; 2DF5; 2EO8; 3GIU; 3LAC; 3RNZ; 3RO0; 5Z40; 5Z47; 5Z48
» more