 |
|
| Entry: PS50113 |
General information about the entry
| Entry name [info] | PAC |
| Accession [info] | PS50113 |
| Entry type [info] | MATRIX |
| Date [info] |
01-DEC-2001 CREATED;
26-FEB-2020 DATA UPDATE; 10-FEB-2021 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC50112 |
| Associated ProRule [info] | PRU00141 |
Name and characterization of the entry
| Description [info] | PAC domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=53; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=48; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.4010999; R2=0.0265788; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=1888.6279297; R2=1.3953488; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=230; H_SCORE=2210; N_SCORE=8.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=155; H_SCORE=2105; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: D=-20; I=-20; B1=*; E1=*; MI=-105; MD=-105; IM=-105; DM=-105; ... A B C D E F G H I K L M N P Q R S T V W Y Z /I: B1=0; BI=-105; BD=-105; /M: SY='R'; M=-10, -8,-25,-11, -2, -8,-20, 2,-15, 1,-10, -4, -4,-16, 6, 8, -6, -4,-15,-15, 2, 1; /M: SY='D'; M= -8, 8,-24, 10, 6,-22,-11, -7,-21, -1,-18,-13, 5, -7, 1, -4, 2, 2,-18,-28,-14, 3; /M: SY='V'; M= -7,-17,-21,-20,-15, -1,-17,-14, 0,-14, -1, -1,-16,-22,-14,-13,-10, -4, 2, -6, 1,-15; /M: SY='E'; M=-10, 10,-27, 17, 36,-28,-17, -3,-27, 7,-21,-18, 3, -2, 13, 1, 2, -5,-25,-31,-18, 24; /M: SY='F'; M= -9,-21,-21,-24,-20, 9,-21,-14, 4,-16, 1, 2,-18,-19,-18,-14,-14, -8, 4, -7, 8,-20; /M: SY='R'; M= -8, -7,-26, -8, 1,-21,-14, -5,-19, 10,-16, -7, -4,-16, 8, 21, -4, -5,-14,-18,-11, 3; /M: SY='L'; M= -8,-24,-21,-28,-21, 11,-27,-16, 16,-21, 20, 14,-21,-25,-19,-18,-18, -8, 13,-16, 4,-20; /M: SY='I'; M= -8,-18,-23,-20,-10, -4,-28,-16, 9,-10, 4, 4,-15,-18, -9, -8,-12, -6, 7,-19, -1,-12; /M: SY='R'; M= -8, 3,-23, -1, 1,-20,-11, 0,-22, 6,-19,-11, 7,-14, 3, 13, -1, -3,-19,-26,-12, 1; /I: I=-8; MI=0; IM=0; DM=-15; MD=-15; /M: SY='K'; M= -5, -5,-25, -5, 0,-22,-15,-11,-21, 12,-19,-11, -3, -1, 1, 12, -5, -6,-17,-24,-14, -1; /M: SY='D'; M=-13, 28,-27, 37, 11,-32, -5, 1,-32, -1,-27,-22, 17, -8, 1, -7, 4, -5,-26,-35,-18, 6; /M: SY='G'; M= -1, -5,-28, -5,-13,-28, 48,-16,-34,-14,-27,-18, 3,-18,-14,-14, 1,-15,-26,-23,-26,-13; /M: SY='S'; M= 0, -1,-19, -3, 4,-22, -8,-10,-21, 0,-20,-14, 2,-10, 3, 3, 12, 10,-14,-29,-16, 3; /M: M= -7,-16,-20,-17, -9,-13,-21,-17, -2, -9, -4, -1,-14, -5, -9, -9, -8, -4, -2,-21,-11,-10; /M: SY='F'; M=-10,-22,-23,-26,-19, 12,-24,-15, 5,-10, 5, 3,-16,-24,-16, -1,-15, -9, 5,-12, 6,-18; /M: SY='W'; M=-13,-25,-33,-25,-18, 1,-22,-12,-11,-16,-12,-10,-23,-12,-14,-14,-19,-12,-16, 47, 14,-15; /M: SY='V'; M= -1,-20, -8,-25,-21, 0,-20,-21, 11,-21, 10, 6,-17,-25,-20,-20,-12, -6, 13,-23, -7,-21; /M: SY='E'; M=-10, -7,-26, -5, 5,-11,-22, 3, -9, -7, 0, -2, -8,-17, 1, -4,-11,-10,-10,-21, -2, 2; /M: SY='V'; M= -1,-19,-19,-21,-16, 0,-19,-19, 6,-18, 7, 2,-17,-22,-15,-16, -8, -2, 8,-17, -5,-16; /I: I=-8; MI=0; MD=-16; IM=0; /M: SY='N'; M= -6, 5,-19, 3, 1,-16,-13, -1,-18, 1,-18,-12, 7,-14, 2, 3, 6, 5,-13,-23, -8, 0; D=-3; /I: DM=-16; /M: SY='A'; M= 8,-16,-18,-20,-16,-11, -4,-20, 2,-15, -2, -1,-12,-19,-16,-16, -3, -3, 7,-22,-12,-17; D=-3; /I: DM=-16; /M: SY='S'; M= 0, -9,-12,-12, -6,-16,-13,-10,-11, -6,-13, -7, -5,-16, -3, -5, 5, 4, -5,-27,-11, -5; /M: SY='P'; M= -2,-19,-27,-15, -6,-18,-17,-20,-10,-13,-13,-11,-18, 35,-13,-18, -8, -8,-12,-27,-21,-12; /M: SY='I'; M= -9,-20,-23,-25,-17, -1,-28,-14, 17,-16, 9, 12,-16,-21,-12,-13,-12, -4, 12,-18, 2,-17; /M: SY='R'; M=-15,-16,-23,-18,-10, 1,-23, -2,-10, 1, -4, -1,-10,-21, -5, 16,-13, -7, -8,-14, 5,-10; /M: SY='D'; M=-13, 27,-27, 33, 7,-26, -4, 1,-30, -4,-26,-22, 19,-15, -2, -8, 2, -6,-26,-26,-12, 2; /M: SY='E'; M= 0, 3,-24, 6, 14,-26, -7, -6,-22, 1,-20,-14, 1, -7, 8, -3, 4, -4,-18,-27,-17, 10; /M: SY='D'; M= -4, 7,-25, 8, 5,-26, -4, -5,-25, 4,-22,-15, 6,-14, 4, 4, 2, -5,-20,-26,-16, 4; /M: SY='G'; M= -6, 6,-29, 10, -3,-32, 35, -8,-37,-10,-28,-20, 6,-16, -6,-12, 0,-15,-30,-26,-24, -5; /I: I=-6; MI=-29; MD=-29; IM=-29; /M: SY='E'; M= -6, 1,-17, 1, 10,-20,-13, 1,-20, 4,-16,-10, 2,-12, 10, 5, 0, -4,-18,-23,-11, 10; D=-6; /I: I=-6; MI=-29; MD=-29; IM=-29; DM=-29; /M: SY='V'; M= -2,-20,-15,-21,-17, 2,-21,-17, 11,-15, 8, 5,-19,-13,-17,-13,-11, -3, 14,-14, -3,-17; D=-6; /I: I=-6; MI=-29; IM=-29; DM=-29; /M: SY='I'; M= -6,-12,-23,-14, -7,-15,-23,-13, 1, -5, -4, 0, -9,-14, -1, -2, -6, -3, 1,-23, -9, -6; /M: SY='G'; M= -8,-10,-27,-11, -7,-11, 4, -2,-18, -6,-12, -7, -5,-19, -6, -3, -8,-13,-16,-14, 0, -8; /M: SY='F'; M= -9,-25,-22,-30,-22, 21,-29,-17, 13,-21, 11, 7,-21,-25,-21,-18,-16, -6, 10, -4, 15,-22; /M: SY='I'; M= -7,-22,-16,-26,-19, -2,-28,-19, 18,-21, 16, 11,-19,-23,-14,-17,-13, -4, 15,-24, -5,-18; /M: SY='G'; M= 2,-16,-13,-19,-20,-13, 19,-21,-15,-20, -9, -8,-11,-23,-20,-19, -5,-11, -7,-23,-18,-20; /M: SY='V'; M= -3,-16,-17,-22,-19, 2,-21,-19, 11,-17, 3, 6,-12,-21,-16,-16, -4, 5, 14,-23, -5,-18; /M: M= -3,-14,-19,-18,-14, -4, -8, -8, -5,-17, -5, -1, -9,-20, -9,-15, -6, -8, -5,-18, -5,-12; /M: SY='R'; M= -8,-10,-24,-12, -3,-16,-21, -5, -8, 3, -7, -1, -5,-17, 5, 13, -4, -3, -7,-24, -9, -1; /M: SY='D'; M=-18, 45,-29, 62, 18,-37,-10, -1,-37, -1,-29,-28, 19, -9, 0,-10, 1, -9,-28,-39,-20, 9; /M: SY='I'; M= -7,-27,-24,-34,-27, -1,-30,-27, 35,-26, 18, 16,-21,-23,-21,-25,-17, -6, 26,-22, -4,-27; /M: SY='T'; M= 2, 1,-12, -6, -7,-14,-13,-16,-13, -9,-15,-12, 2,-11, -7, -9, 22, 37, -4,-32,-13, -7; /M: SY='E'; M= -5, 9,-27, 15, 27,-30,-12, -3,-26, 4,-20,-16, 1, -4, 11, -3, 0, -9,-23,-28,-18, 19; /M: SY='R'; M=-11,-10,-26,-12, 0,-14,-21, 2,-15, 5, -6, -2, -6,-18, 8, 19, -9, -7,-13,-21, -5, 2; /M: SY='K'; M=-11, -4,-28, -4, 3,-21,-21, -3,-19, 25,-19, -6, -3,-14, 6, 19, -9, -8,-13,-20, -5, 3; /M: SY='Q'; M= -7, -3,-26, -3, 16,-23,-19, -3,-16, 7,-11, -3, -3,-12, 18, 10, -3, -5,-17,-24,-12, 16; /M: SY='A'; M= 15,-16,-17,-21,-13, -9,-13,-19, -1,-14, 0, -1,-14, -9,-12,-17, -2, 0, 2,-21,-11,-13; /M: SY='E'; M= -8, -2,-28, 0, 22,-23,-19, -2,-15, 3,-10, -5, -4,-11, 18, 2, -5, -9,-18,-23,-10, 19; /M: SY='E'; M= -4, 3,-25, 5, 12,-24,-15, -2,-17, 1,-13, -8, 0,-12, 12, 1, -1, -7,-17,-26,-12, 12; /M: SY='E'; M= 1, -1,-24, -2, 11,-24,-15, -5,-19, 8,-16, -9, 0,-10, 9, 11, -1, -7,-17,-24,-15, 9; /M: SY='L'; M= -7,-22,-21,-23,-13, 4,-26,-17, 9,-19, 28, 11,-22,-25,-13,-12,-20, -8, 4,-20, -3,-13; /M: SY='Q'; M= -5, -1,-25, -3, 7,-24,-17, 1,-16, 6,-15, -7, 2,-13, 14, 10, -1, -4,-16,-25,-11, 9; /M: SY='E'; M= -5, 2,-23, 2, 13,-23,-15, -4,-22, 8,-17,-12, 2,-11, 9, 12, -2, -5,-19,-25,-14, 10; /I: E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
| Total number of hits | 145 in 116 different sequences |
| Number of true positive hits | 145 in 116 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 107 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 57.54 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | K_Hofmann |
| Taxonomic range [info] | Archaea, Eukaryotes, Prokaryotes (Bacteria) |
| Maximum number of repetitions [info] | 4 |
| Feature key [info] | DOMAIN |
| Feature description [info] | PAC |
| Version [info] | 6 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
116 sequences
ARCB_ECO57 (P58363 ), ARCB_ECOLI (P0AEC3 ), ARCB_SHIFL (P0AEC4 ), ATOS_ECOLI (Q06067 ), BAT_HALSA (Q9HPU8 ), BDLA_PSEAE (Q9I3S1 ), BVGS_BORBR (P26762 ), BVGS_BORPA (P40330 ), BVGS_BORPE (P16575 ), DCRA_DESVH (P35841 ), DCTS_RHOCA (P37739 ), DGCE_ECOLI (P38097 ), DGCM_ECO57 (Q8X8Q3 ), DGCM_ECOLI (P77302 ), DGC_VIBC3 (A0A0H3AFM6), DHKD_DICDI (Q54SP4 ), DHKF_DICDI (Q551X9 ), DHKI_DICDI (Q86AT9 ), DOSP_ECOLI (P76129 ), FILI_METH6 (E5KK10 ), FIXL_AZOC5 (P26489 ), FIXL_BRADU (P23222 ), FIXL_RHIME (P10955 ), KCNAE_DROME (Q02280 ), KCNH1_BOVIN (O18965 ), KCNH1_HUMAN (O95259 ), KCNH1_MOUSE (Q60603 ), KCNH1_RAT (Q63472 ), KCNH2_CANLF (Q9TSZ3 ), KCNH2_HUMAN (Q12809 ), KCNH2_MOUSE (O35219 ), KCNH2_RABIT (Q8WNY2 ), KCNH2_RAT (O08962 ), KCNH3_HUMAN (Q9ULD8 ), KCNH3_MOUSE (Q9WVJ0 ), KCNH3_RAT (O89047 ), KCNH4_HUMAN (Q9UQ05 ), KCNH4_RAT (Q9R1T9 ), KCNH5_HUMAN (Q8NCM2 ), KCNH5_MOUSE (Q920E3 ), KCNH5_RAT (Q9EPI9 ), KCNH8_HUMAN (Q96L42 ), KCNH8_MOUSE (P59111 ), KCNH8_RAT (Q9QWS8 ), KINC_BACSU (P39764 ), LOVHK_BRUA1 (B2SB67 ), LOVHK_BRUA2 (Q2YKK7 ), LOVHK_BRUAB (Q577Y7 ), LOVHK_BRUC2 (A9MBM8 ), LOVHK_BRUME (Q8YC53 ), LOVHK_BRUO2 (A5VUS1 ), LOVHK_BRUSI (A9WYQ7 ), LOVHK_BRUSU (Q8FW73 ), LOVHK_OCHA4 (A6X554 ), LOVHK_PSE14 (Q48IV1 ), LOVHK_PSESM (Q881J7 ), LOVHK_PSEU2 (Q4ZSY3 ), LOVHK_RHIL3 (Q1M667 ), LVHK1_ERYLH (Q2NCA3 ), LVHK2_ERYLH (Q2NB77 ), LVHTH_ERYLH (Q2NB98 ), MAK1_SCHPO (Q9P7Q7 ), MAK3_SCHPO (O74539 ), MSMS_METAC (Q8THF6 ), MTDRP_MYCTO (P9WLZ6 ), MTDRP_MYCTU (P9WLZ7 ), NIFL_AZOVI (P30663 ), NIFL_KLEOX (P56267 ), NIFL_KLEPN (P06772 ), NODV_BRADU (P15939 ), PHOT1_ARATH (O48963 ), PHOT2_ARATH (P93025 ), PHOT2_ORYSJ (Q9ST27 ), PHOT_BACSU (O34627 ), PHOT_CHLRE (Q8LPD9 ), PHOT_LISIN (Q92DM1 ), PHOT_LISMO (P58724 ), PHT1A_ORYSJ (Q2QYY8 ), PHT1B_ORYSJ (Q2RBR1 ), PHY1_CERPU (P25848 ), PHY1_SELMA (Q01549 ), PHYA1_TOBAC (P33530 ), PHYA2_SOYBN (B4YB07 ), PHYA_SOLTU (P30733 ), PHYE_IPONI (P55004 ), PHY_MOUSC (P33529 ), PPRA_PSEAE (Q9HWA7 ), TCSA_EMENI (Q9P896 ), TDIS_THAAR (O87939 ), TLOV1_ARATH (O64511 ), TMOS_PSEME (Q8KIY1 ), TODS_PSEP1 (A5W4E3 ), TODS_PSEPT (E0X9C7 ), WALK_BACSU (Q45614 ), WALK_STAA1 (A7WWQ7 ), WALK_STAA2 (A6TXG9 ), WALK_STAA3 (Q2FKN7 ), WALK_STAA8 (Q2G2U4 ), WALK_STAA9 (A5INR0 ), WALK_STAAB (Q2YUQ2 ), WALK_STAAC (Q5HJX6 ), WALK_STAAE (A6QD58 ), WALK_STAAM (Q7A305 ), WALK_STAAN (Q7A8E0 ), WALK_STAAR (Q6GKS6 ), WALK_STAAS (Q6GD71 ), WALK_STAAT (A8YYU2 ), WALK_STAAU (Q9RDT3 ), WALK_STAAW (Q7A215 ), WALK_STAEQ (Q5HK19 ), WALK_STAES (Q8CU87 ), WALK_STAHJ (Q4LAJ8 ), WALK_STAS1 (Q4A159 ), Y1002_RHIME (Q52969 ), Y3085_AZOC5 (Q04855 ), Y4LL_SINFN (P55552 )» more
|
| UniProtKB/Swiss-Prot False negative sequences |
107 sequences
ADO1_ARATH (Q94BT6 ), ADO2_ARATH (Q8W420 ), ADO3_ARATH (Q9C9W9 ), AHA1_CAEEL (O02219 ), AHR_DELLE (Q95LD9 ), AHR_HUMAN (P35869 ), AHR_MOUSE (P30561 ), AHR_MUSCR (Q8R4S7 ), AHR_MUSMC (Q8R4S6 ), AHR_MUSMM (Q8R4S5 ), AHR_MUSSI (Q8R4S4 ), AHR_MUSSP (Q8R4S2 ), AHR_RABIT (O02747 ), AHR_RAT (P41738 ), ARNT2_DANRE (Q9DG12 ), ARNT2_HUMAN (Q9HBZ2 ), ARNT2_MOUSE (Q61324 ), ARNT2_RAT (Q78E60 ), ARNT_BOVIN (Q9BE97 ), ARNT_DROME (O15945 ), ARNT_HUMAN (P27540 ), ARNT_MOUSE (P53762 ), ARNT_ONCMY (P79832 ), ARNT_RABIT (O02748 ), ARNT_RAT (P41739 ), BMAL1_CHICK (Q9I8T7 ), BMAL1_HORSE (A0MLS5 ), BMAL1_HUMAN (O00327 ), BMAL1_MESAU (O88529 ), BMAL1_MOUSE (Q9WTL8 ), BMAL1_NANGA (Q91YA9 ), BMAL1_PONAB (Q5R4T2 ), BMAL1_RAT (Q9EPW1 ), BMAL1_TYTAL (Q6YGZ5 ), BMAL2_CHICK (Q8QGQ7 ), BMAL2_HUMAN (Q8WYA1 ), BMAL2_MOUSE (Q2VPD4 ), CLOCK_CHICK (Q8QGQ6 ), CLOCK_HUMAN (O15516 ), CLOCK_MOUSE (O08785 ), CLOCK_NANGA (Q91YB0 ), CLOCK_PONAB (Q5RAK8 ), CLOCK_RAT (Q9WVS9 ), CLOCK_SPACA (Q91YB2 ), CLOCK_SPAJD (Q91YA8 ), CLOCK_TYTAL (Q6YGZ4 ), CYCL_DROME (O61734 ), DHKA_DICDI (Q54U87 ), DHKL_DICDI (Q54RP6 ), EPAS1_HUMAN (Q99814 ), EPAS1_MOUSE (P97481 ), EPAS1_RAT (Q9JHS1 ), HIF1A_BOSMU (Q0PGG7 ), HIF1A_BOVIN (Q9XTA5 ), HIF1A_CHICK (Q9YIB9 ), HIF1A_EOSFB (Q309Z6 ), HIF1A_HUMAN (Q16665 ), HIF1A_MOUSE (Q61221 ), HIF1A_ONCMY (Q98SW2 ), HIF1A_RAT (O35800 ), HIF1A_XENLA (Q9I8A9 ), HIF1_CAEEL (G5EGD2 ), KCNH6_CHICK (Q9PT84 ), KCNH6_HUMAN (Q9H252 ), KCNH6_RAT (O54853 ), KCNH7_HUMAN (Q9NS40 ), KCNH7_MOUSE (Q9ER47 ), KCNH7_RAT (O54852 ), KINA_BACSU (P16497 ), KINB_PSEAI (O34206 ), NPAS1_HUMAN (Q99742 ), NPAS1_MOUSE (P97459 ), NPAS2_CHICK (Q5ZQU2 ), NPAS2_HUMAN (Q99743 ), NPAS2_MOUSE (P97460 ), NPAS3_HUMAN (Q8IXF0 ), NPAS3_MOUSE (Q9QZQ0 ), NPAS4_HUMAN (Q8IUM7 ), NPAS4_MOUSE (Q8BGD7 ), NPAS4_RAT (Q8CJH6 ), NPS4A_DANRE (Q1ECW2 ), PDE8A_HUMAN (O60658 ), PDE8A_MOUSE (O88502 ), PER1_HUMAN (O15534 ), PER1_MOUSE (O35973 ), PER1_RAT (Q8CHI5 ), PER1_SPAJD (Q8K3T3 ), PER2_CHICK (Q8QGQ8 ), PER2_HUMAN (O15055 ), PER2_MOUSE (O54943 ), PER2_RAT (Q9Z301 ), PER2_SPAJD (Q8K3T2 ), PER3_HUMAN (P56645 ), PER3_MOUSE (O70361 ), PER3_RAT (Q8CJE2 ), PHYA_ARATH (P14712 ), SIM1A_DANRE (Q98SJ5 ), SIM1_HUMAN (P81133 ), SIM1_MOUSE (Q61045 ), SIM1_PANPA (A1YFY6 ), SIM1_PANTR (A2T6X9 ), SIM2_HUMAN (Q14190 ), SIM2_MOUSE (Q61079 ), SIMA_DROME (Q24167 ), TRH_DROME (Q24119 ), WALK_STASR (A5A2P0 ), WC1_NEUCR (Q01371 )» more |
| PDB [Detailed view] |
83 PDB
1BYW; 1DP6; 1DP8; 1DP9; 1DRM; 1LSV; 1LSW; 1LSX; 1LT0; 1N9L; 1N9N; 1N9O; 1S66; 1S67; 1V9Y; 1V9Z; 1VB6; 1XJ2; 1XJ3; 1XJ4; 1XJ6; 1Y28; 2CMN; 2GJ3; 2L0W; 2L1M; 2L4R; 2MWG; 2OWH; 2OWJ; 2PR5; 2PR6; 2VV6; 2VV7; 2VV8; 2Z6C; 2Z6D; 3K3C; 3K3D; 3KX0; 3P7N; 3T50; 4EEP; 4EER; 4EES; 4EET; 4EEU; 4GCZ; 4HHD; 4HOI; 4HP9; 4HQA; 4LLO; 4MN5; 4MN6; 4NXB; 4NXE; 4NXF; 4NXG; 4R38; 4R3A; 5EPV; 5HWT; 5HWV; 5HWW; 5J7E; 5K7L; 5VA1; 5VA2; 5VA3; 6GPU; 6GPV; 6PBX; 6PBY; 6PPS; 6QQH; 6QQI; 6QQJ; 6QQK; 6QSA; 6S45; 6S46; 6Y7Q » more |
View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission