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| Entry: PS50137 |
General information about the entry
| Entry name [info] | DS_RBD |
| Accession [info] | PS50137 |
| Entry type [info] | MATRIX |
| Date [info] |
01-DEC-2001 CREATED;
10-MAY-2017 DATA UPDATE; 10-FEB-2021 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC50137 |
| Associated ProRule [info] | PRU00266 |
Name and characterization of the entry
| Description [info] | Double stranded RNA-binding domain (dsRBD) profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=69; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=64; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.5994000; R2=0.0242763; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=2441.8774414; R2=4.2387094; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=285; H_SCORE=3650; N_SCORE=8.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=202; H_SCORE=3298; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: D=-20; I=-20; B1=-60; E1=-60; MI=-105; MD=-105; IM=-105; DM=-105; ... A B C D E F G H I K L M N P Q R S T V W Y Z /I: B1=0; BI=-105; BD=-105; /M: SY='N'; M= -9, 24,-22, 20, 4,-20, -9, 7,-24, -2,-24,-18, 27,-15, 0, -3, 7, 2,-23,-34,-13, 2; /M: SY='P'; M= -2,-19,-26,-17,-10,-14,-17,-14,-11,-12,-17,-11,-18, 31,-12,-18, -8, -8,-15,-15, -7,-14; /M: SY='V'; M= -7,-17,-20,-20,-13,-12,-27,-20, 7, 3, -2, 6,-15,-16,-10, -4,-13, -5, 10,-24, -8,-13; /M: SY='S'; M= -4, 1,-19, 1, 2,-23, -4,-10,-21, 0,-20,-12, 3,-14, 0, 0, 6, 1,-15,-29,-17, 0; /M: M= -1,-13,-22,-14, -3,-10,-15,-13, -9, -1, -4, -2,-11,-14, -3, 0, -7, -6, -6,-20,-10, -3; /M: SY='L'; M= -9,-30,-19,-30,-22, 8,-30,-21, 23,-28, 42, 21,-29,-29,-20,-20,-27, -9, 16,-21, -1,-21; /M: SY='N'; M= -8, 6,-23, -2, -1,-14,-15, 9,-10, -4,-10, -1, 13,-19, 8, -3, -3, -6,-17,-23, -2, 2; /M: SY='E'; M= -2, 5,-26, 9, 28,-26,-16, -4,-23, 7,-18,-13, -1, -7, 14, 0, 2, -6,-21,-26,-14, 20; /M: SY='F'; M=-13,-26,-16,-30,-23, 23,-28,-14, 4,-22, 13, 3,-23,-29,-21,-18,-21,-10, 0, 8, 22,-22; /M: SY='A'; M= 6,-13, -2,-19,-12,-10,-12,-16, -8,-11, -5, -2, -9,-19,-11,-12, -3, -4, -4,-25,-13,-11; /I: MD=-25; /M: SY='Q'; M= -8, -1,-25, -1, 13,-27,-12, 2,-21, 8,-17, -6, 1,-11, 26, 11, -1, -5,-22,-21,-11, 18; D=-4; /I: I=-5; MI=0; MD=-15; IM=0; DM=-15; /M: SY='K'; M= -9, -5,-25, -7, 2,-16,-15, -4,-16, 14,-15, -3, -2,-15, 4, 12, -5, -6,-13,-20, -5, 2; D=-4; /I: DM=-15; /M: SY='R'; M= -8, -6,-25, -8, -1,-15,-16, 1,-13, 2, -8, -4, -3,-17, 1, 5, -7, -5,-12,-22, -4, -1; /M: SY='R'; M= -7, -4,-27, -4, -3,-19, -3, -9,-21, 4,-14,-10, -2,-18, -1, 6, -7,-10,-18,-14,-10, -3; /M: SY='M'; M=-11,-17,-24,-20,-11, -1,-21,-14, -1, -9, -3, 1,-12, -7, -8, -5,-13, -9, -4,-19, -6,-11; /M: SY='T'; M= -4, -2,-23, -4, 0,-19,-11, -4,-15, -5,-12, -8, 0,-11, 0, -4, 1, 2,-13,-27,-12, -1; /M: SY='P'; M= -7,-21,-14,-20,-15,-13,-22,-19, -1,-17, -2, -2,-21, 10,-17,-19,-14, -8, -1,-24,-15,-18; /M: SY='E'; M= -8, 6,-22, 4, 9,-19,-17, -1,-15, 0,-16,-10, 8,-12, 5, -2, 4, 4,-14,-29,-12, 6; /M: SY='Y'; M=-19,-23,-27,-25,-21, 42,-29, 5, -1,-16, 3, -1,-20,-29,-19,-13,-19,-10, -8, 23, 58,-21; /M: SY='E'; M=-11, 1,-27, 4, 13,-22,-15, -7,-22, 13,-15,-11, -1,-13, 4, 11, -5, -6,-17,-24,-11, 8; /M: SY='L'; M=-10,-15,-22,-15,-11, -2,-27,-16, 8,-17, 13, 5,-17,-22,-12,-16,-14, -3, 6,-18, -1,-12; /M: SY='V'; M= -6,-15,-12,-18,-13, -8,-26,-19, 7,-12, 3, 1,-13,-21,-13,-11, -7, 0, 10,-26, -7,-14; /I: MD=-21; /M: SY='E'; M= -2, 0,-24, 3, 10,-24,-15, -6,-17, 1,-18,-12, -1, 0, 6, -4, 3, -3,-15,-28,-15, 7; D=-4; /I: MD=-21; /M: SY='E'; M= -6, 4,-20, 6, 15,-20,-12, -3,-16, 6,-13, -9, 1, -7, 10, 2, -1, -3,-15,-20,-11, 12; D=-4; /I: I=-2; MI=0; MD=-21; IM=0; DM=-21; /M: SY='T'; M= -2, -6,-15, -6, 0,-14,-11,-11, -9, -6,-11, -8, -3, -1, -3, -6, 7, 8, -5,-24,-13, -2; D=-4; /I: DM=-21; /M: SY='G'; M= 0, -3,-22, -5,-11,-22, 38,-13,-28,-13,-23,-16, 5,-15,-12,-12, 4, -8,-21,-21,-22,-12; D=-4; /I: DM=-21; /M: SY='P'; M= -5, -8,-26, -5, 1,-21,-11,-12,-14, -7,-16,-11, -7, 24, -4,-11, -3, -4,-16,-26,-19, -3; D=-4; /I: DM=-21; /M: SY='A'; M= 5, -3,-22, -1, 1,-23, -4,-12,-17, -6,-20,-14, -3, 1, -5,-12, 5, -3,-11,-29,-20, -3; /M: SY='H'; M=-13, 2,-27, -1, -4,-20, -3, 41,-25, -6,-18, -5, 10,-19, 2, -1, -5,-13,-25,-28, 0, -3; /M: SY='E'; M= -3, 0,-18, 1, 3,-24,-13, -6,-22, 1,-19,-12, 0, -3, 3, 2, 2, -1,-18,-29,-16, 1; /M: SY='P'; M=-11, -7,-26, -6, 5,-24,-20, -2,-18, 6,-20, -8, -5, 10, 8, 5, -7, -9,-19,-25,-13, 4; /M: SY='R'; M= -9, -6,-25, -6, 2,-19,-11, -6,-17, 6,-16, -8, -1,-13, 3, 12, -1, -3,-13,-24,-11, 1; /M: SY='F'; M=-18,-27,-14,-35,-27, 59,-29,-16, -2,-27, 5, -2,-19,-29,-33,-19,-17, -8, -1, 8, 26,-27; /M: SY='T'; M= -5,-15,-19,-20,-13, -6,-26,-16, 8,-12, 7, 6,-14,-19,-10,-12, -5, 9, 9,-24, -4,-13; /M: SY='V'; M= -1,-21, 7,-28,-22, 5,-24,-18, 4,-19, 1, 5,-19,-25,-20,-19,-10, -4, 9,-20, -1,-21; /M: SY='E'; M= -5, -3,-10, -4, 10,-21,-20, -4,-18, 1,-17,-10, -2,-13, 7, -1, 2, 0,-15,-27,-10, 8; /M: SY='V'; M= -3,-26, 13,-29,-25, -4,-28,-25, 12,-22, 11, 7,-25,-30,-24,-20,-14, -5, 21,-30,-12,-25; /M: SY='R'; M= -7, -9,-23,-11, -3, -8,-22,-13, -6, -1, -8, -4, -8,-16, -5, 1, -4, -1, -3,-19, -6, -4; /M: SY='V'; M= -4,-24,-18,-29,-25, 1,-27,-25, 25,-22, 14, 12,-21,-24,-22,-21,-11, -1, 27,-25, -6,-24; /M: SY='G'; M= -8, 10,-24, 12, 2,-26, 13, -7,-30, -6,-27,-20, 10, -9, -4,-10, 2, -9,-26,-28,-18, -2; /M: SY='G'; M= -4, -2,-26, 0, -2,-27, 14,-12,-24, -8,-22,-14, 0, -7, -3,-11, 2, -8,-19,-26,-21, -3; /M: SY='Q'; M= -5, -9,-24,-12, -2,-12,-21, -8, -7, 0, -9, -4, -5,-13, 2, 2, -4, -2, -7,-21, -6, -2; /M: SY='T'; M= -4, -4,-22, -6, 5,-16,-17,-13,-12, -2,-14, -9, -4, -6, -1, -6, 2, 6, -9,-23,-13, 1; /I: MD=-17; /M: SY='Y'; M=-12,-17,-19,-18,-15, 22,-23, -4, 2,-13, 5, 1,-15,-19,-16,-11,-14, -7, 0, 0, 23,-16; D=-3; /I: I=-5; MI=0; MD=-17; IM=0; DM=-17; /M: SY='G'; M= 5, -7, -6, -9, -8,-18, 6,-16,-19,-11,-18,-14, -6, -1,-11,-14, 3, -3,-13,-23,-19,-10; D=-3; /I: DM=-17; /M: SY='E'; M= -5, -6,-22, -7, 4,-16,-19, -3,-13, 1,-13, -6, -5,-11, 0, 3, 1, 3, -7,-26,-10, 1; /M: SY='G'; M= 9,-10,-24,-12,-14,-24, 41,-19,-28,-16,-22,-16, -4,-17,-17,-19, 2,-12,-18,-21,-25,-15; /M: SY='S'; M= -3, -1,-14, -4, -2,-15,-16, -8,-11, -6,-15, -9, 1,-16, -4, -8, 5, 4, -7,-26,-10, -3; /M: SY='G'; M= 7, -8,-25, -9,-15,-27, 49,-18,-33,-16,-27,-19, 1,-18,-15,-16, 6,-12,-24,-23,-27,-15; /M: SY='T'; M= -3, -6,-18, -8, -5,-16,-13,-10,-17, -2,-20,-12, 0, -1, -4, 1, 8, 9,-12,-28,-13, -6; /M: SY='S'; M= 1, 12,-15, 4, -2,-19, -2, -5,-19, -5,-27,-18, 23,-13, -1, -5, 24, 15,-15,-37,-18, -2; /M: SY='K'; M=-11, -4,-26, -5, 4,-24,-21, -8,-23, 34,-22, -7, -3,-13, 7, 24,-10, -9,-16,-20, -7, 5; /M: SY='K'; M=-11, -1,-30, 0, 12,-30,-18, -7,-29, 39,-27,-10, 0,-11, 15, 29, -8,-10,-22,-21,-11, 13; /M: SY='E'; M= -5, 3,-23, 7, 11,-21,-19, -8,-12, -2,-11,-10, -2,-13, 1, -6, -1, -3, -8,-29,-14, 5; /M: SY='A'; M= 44, -9,-11,-18, -9,-20, 1,-19,-12,-10,-13,-11, -8, -9, -9,-19, 12, 1, -2,-22,-20, -9; /M: SY='K'; M= -7, 0,-29, 0, 14,-29,-14, -4,-28, 29,-25,-11, 0,-10, 14, 21, -5,-10,-22,-22,-12, 14; /M: SY='Q'; M= -2, 0,-24, -5, 2,-24,-12, 3,-15, 3,-16, -6, 6,-15, 16, 5, 1, -5,-17,-25,-11, 8; /M: SY='N'; M= -4, 4,-22, 1, -1,-17,-15, -1,-13, -2,-10, -7, 6,-17, -1, 1, -2, -3,-12,-27, -9, -2; /M: SY='A'; M= 41,-12, 4,-22,-13,-19, -5,-22,-10,-13,-10,-10,-12,-14,-13,-21, 7, -1, 1,-24,-21,-13; /M: SY='A'; M= 48,-10, -7,-20,-11,-20, -1,-20,-11,-11,-10,-10,-10,-11,-11,-20, 9, 0, 0,-21,-20,-11; /M: SY='K'; M= -7, -7,-24, -7, 5,-17,-20, -7,-12, 8, -9, -2, -8,-15, 3, 6, -7, -5, -8,-21, -9, 3; /M: SY='B'; M= -7, 7,-24, 7, 6,-21,-15, -6,-18, 5,-14,-10, 5,-15, 3, 4, -2, -5,-16,-28,-13, 4; /M: SY='A'; M= 24,-18,-15,-26,-17, -3,-13,-19, 4,-16, 3, 2,-16,-17,-15,-20, -3, -3, 7,-17, -8,-16; /M: SY='L'; M= -9,-28,-13,-30,-23, 9,-30,-19, 17,-25, 30, 15,-28,-30,-21,-19,-24, -8, 15,-15, 4,-22; /M: SY='Q'; M=-12, 5,-28, 7, 15,-28,-18, -1,-23, 14,-19, -9, 4,-12, 19, 16, -4, -7,-21,-25,-13, 16; /M: SY='Q'; M= -7, -7,-26, -7, 1,-14,-23, -5, -6, 3, -8, -3, -8,-16, 4, -2, -9, -9, -7,-16, 3, 1; /M: SY='L'; M=-10,-28,-21,-30,-20, 9,-29,-19, 18,-25, 38, 21,-27,-28,-18,-18,-26, -9, 10,-16, 1,-19; /M: M= -7, -7,-24, -7, -6, -8,-11, -7,-10, -6, -6, -4, -7,-19, -7, -7, -8, -9, -7,-20, -4, -7; /M: M= -8, -5,-22, -7, -3,-17,-12, -1,-14, -2,-10, -4, -3,-14, -1, 0, -5, -4,-13,-23, -7, -3; /I: E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
| Total number of hits | 749 in 633 different sequences |
| Number of true positive hits | 748 in 632 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 1 |
| Number of false negative sequences | 58 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 99.87 % |
| Recall (true positives / (true positives + false negatives)) | 92.80 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | K_Hofmann |
| Taxonomic range [info] | Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses |
| Maximum number of repetitions [info] | 5 |
| Feature key [info] | DOMAIN |
| Feature description [info] | DRBM |
| Version [info] | 5 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
632 sequences
340R_IIV6 (Q91FI4 ), A464_PBCV1 (Q98514 ), ADAD1_HUMAN (Q96M93 ), ADAD1_MOUSE (Q5SUE7 ), ADAD1_RAT (Q3KR54 ), ADAD1_XENLA (Q32NG0 ), ADAD2_HUMAN (Q8NCV1 ), ADAD2_MACFA (Q95JV3 ), ADAD2_MOUSE (Q9D5P4 ), ADAR_DROME (Q9NII1 ), ADR1_CAEEL (Q9U3D6 ), CARF_HUMAN (Q9NXV6 ), CARF_MOUSE (Q8BI72 ), CARF_RAT (Q5U2X0 ), CPL1_ARATH (Q5YDB6 ), CPL2_ARATH (Q5YDB5 ), DCL1_ARATH (Q9SP32 ), DCL1_CHAGB (Q2H0G2 ), DCL1_ORYSJ (Q8LMR2 ), DCL2A_ORYSJ (Q10HL3 ), DCL2B_ORYSJ (Q69LX2 ), DCL2_ARATH (Q3EBC8 ), DCL2_MAGO7 (A4RHU9 ), DCL2_NEUCR (Q7SCC1 ), DCL4_ARATH (P84634 ), DCL4_ORYSJ (A7LFZ6 ), DCR1_CAEEL (P34529 ), DCR1_DROME (Q9VCU9 ), DGCR8_BOVIN (A6QR44 ), DGCR8_HUMAN (Q8WYQ5 ), DGCR8_MOUSE (Q9EQM6 ), DHX9_BOVIN (Q28141 ), DHX9_CAEEL (Q22307 ), DHX9_HUMAN (Q08211 ), DHX9_MOUSE (O70133 ), DHX9_PONAB (Q5R874 ), DHX9_XENLA (Q68FK8 ), DICER_BOVIN (Q6TUI4 ), DICER_CHICK (Q25BN1 ), DICER_CRIGR (A0MQH0 ), DICER_DANRE (Q6TV19 ), DICER_HUMAN (Q9UPY3 ), DICER_MOUSE (Q8R418 ), DICER_XENTR (B3DLA6 ), DRB1_ARATH (O04492 ), DRB1_ORYSJ (Q5N8Z0 ), DRB2_ARATH (Q9SKN2 ), DRB2_ORYSJ (Q0DKP4 ), DRB3_ARATH (Q9LJF5 ), DRB3_ORYSJ (Q0DJA3 ), DRB4_ARATH (Q8H1D4 ), DRB4_ORYSJ (Q6YW64 ), DRB5_ARATH (Q8GY79 ), DRB5_ORYSJ (B7E321 ), DRB6_ORYSJ (Q9AV50 ), DRB7_ORYSJ (Q0IV63 ), DRB8_ORYSJ (Q0IQN6 ), DSRAD_CAEEL (Q22618 ), DSRAD_HUMAN (P55265 ), DSRAD_MOUSE (Q99MU3 ), DSRAD_RAT (P55266 ), E2AK2_HUMAN (P19525 ), E2AK2_MOUSE (Q03963 ), E2AK2_RAT (Q63184 ), E3_VACCC (P21081 ), E3_VACCW (P21605 ), E3_VAR67 (P33863 ), ILF3A_XENLA (Q91550 ), ILF3B_XENLA (Q6DD04 ), ILF3_DANRE (Q6NXA4 ), ILF3_HUMAN (Q12906 ), ILF3_MOUSE (Q9Z1X4 ), ILF3_RAT (Q9JIL3 ), ILF3_XENTR (Q6GL57 ), MLE_DROME (P24785 ), NS5_BAVJK (Q9YIT9 ), NSP1N_ROTB2 (Q0H8C5 ), NSP1N_ROTJ1 (Q45UF6 ), NSP3_ROTBS (P34717 ), NSP3_ROTHC (Q9PY95 ), NSP3_ROTPC (P27586 ), PAC1_SCHPO (P22192 ), POLN_DCVEB (O36966 ), PRKAA_XENLA (Q7ZYA5 ), PRKAB_XENLA (Q91836 ), PRKRA_BOVIN (Q2HJ92 ), PRKRA_DANRE (B0V3F8 ), PRKRA_HUMAN (O75569 ), PRKRA_MOUSE (Q9WTX2 ), PRKRA_RAT (Q4V8C7 ), RED1_HUMAN (P78563 ), RED1_MOUSE (Q91ZS8 ), RED1_RAT (P51400 ), RED2_HUMAN (Q9NS39 ), RED2_MOUSE (Q9JI20 ), RED2_RAT (P97616 ), RM03_YEAST (P36516 ), RM44_HUMAN (Q9H9J2 ), RM44_MOUSE (Q9CY73 ), RM44_PONAB (Q5REY8 ), RNC1_NOSS1 (Q8Z023 ), RNC1_SYNY3 (P74368 ), RNC2_NOSS1 (Q8YPT4 ), RNC2_SYNY3 (Q55637 ), RNC_ACIAD (Q6F9C2 ), RNC_ACIB3 (B7GYT0 ), RNC_ACIBS (B0VTM5 ), RNC_ACIBT (A3M7P2 ), RNC_ACIBY (B0VCU0 ), RNC_ACICP (F0KKL2 ), RNC_ACTP2 (A3MZQ9 ), RNC_ACTPJ (B0BUA6 ), RNC_ACTSZ (A6VLV8 ), RNC_AGRFC (Q8UGK2 ), RNC_AGRRK (B9JC73 ), RNC_AGRVS (B9JUN7 ), RNC_ALCBS (Q0VP19 ), RNC_ALIF1 (Q5E314 ), RNC_ALKEH (Q0A8Z1 ), RNC_ANAMF (B9KGT5 ), RNC_ANAMM (Q5P9U8 ), RNC_ANAPZ (Q2GIW0 ), RNC_ANOFW (B7GGE9 ), RNC_AQUAE (O67082 ), RNC_ARCB4 (A8EV88 ), RNC_AROAE (Q5P086 ), RNC_AYWBP (Q2NJY3 ), RNC_AZOC5 (A8I3B5 ), RNC_AZOPC (B6YQI6 ), RNC_AZOVD (C1DQS2 ), RNC_BACAA (C3P5Q0 ), RNC_BACAC (C3L778 ), RNC_BACAN (Q81WI8 ), RNC_BACC0 (B7JJT6 ), RNC_BACC1 (Q732M1 ), RNC_BACC2 (B7IUK8 ), RNC_BACC3 (C1EP73 ), RNC_BACC4 (B7HDX2 ), RNC_BACC7 (B7HLI2 ), RNC_BACCN (A7GRH9 ), RNC_BACCQ (B9IVD8 ), RNC_BACCR (Q819V8 ), RNC_BACCZ (Q636H7 ), RNC_BACFN (Q5LIS2 ), RNC_BACFR (Q64ZV9 ), RNC_BACHD (Q9KA05 ), RNC_BACHK (Q6HEW6 ), RNC_BACLD (Q65JQ5 ), RNC_BACMK (A9VT87 ), RNC_BACSK (Q5WFM6 ), RNC_BACSU (P51833 ), RNC_BACTN (Q8A2E8 ), RNC_BACV8 (A6KZ76 ), RNC_BACVZ (A7Z4L3 ), RNC_BARBK (A1US36 ), RNC_BARHE (Q6G459 ), RNC_BARQU (Q6G082 ), RNC_BART1 (A9IRN0 ), RNC_BDEBA (Q6MLR5 ), RNC_BIFLO (Q8G7H1 ), RNC_BLOFL (Q7VRR0 ), RNC_BLOPB (Q492D1 ), RNC_BORA1 (Q2KWY0 ), RNC_BORAP (Q0SMF0 ), RNC_BORBP (Q660G7 ), RNC_BORBR (Q7WD32 ), RNC_BORBU (O51648 ), RNC_BORPA (Q7W5J6 ), RNC_BORPD (A9IIJ2 ), RNC_BORPE (Q7VW39 ), RNC_BRADU (O69161 ), RNC_BRUA1 (B2SAD9 ), RNC_BRUA2 (Q2YN02 ), RNC_BRUAB (Q57E81 ), RNC_BRUC2 (A9MA35 ), RNC_BRUMB (C0RI03 ), RNC_BRUME (P66664 ), RNC_BRUSI (B0CKY7 ), RNC_BRUSU (P66665 ), RNC_BUCA5 (B8D951 ), RNC_BUCAI (P57346 ), RNC_BUCAP (Q8K9R1 ), RNC_BUCAT (B8D7F5 ), RNC_BUCBP (P59476 ), RNC_BUCCC (Q057R4 ), RNC_CAEBR (Q61XX9 ), RNC_CAEEL (O01326 ), RNC_CALS4 (Q8R9W3 ), RNC_CAMC1 (A8Z6F6 ), RNC_CAMC5 (A7H186 ), RNC_CAMFF (A0RRM7 ), RNC_CAMJ8 (A8FNU7 ), RNC_CAMJD (A7H5Y2 ), RNC_CAMJE (Q9PM40 ), RNC_CAMJR (Q5HSF8 ), RNC_CARHZ (Q3AC58 ), RNC_CAUSK (B0T3I0 ), RNC_CAUVC (Q9A805 ), RNC_CAUVN (B8H627 ), RNC_CHLAA (A9WJ69 ), RNC_CHLAB (Q5L6E3 ), RNC_CHLAD (B8GAM6 ), RNC_CHLCH (Q3AQ14 ), RNC_CHLCV (Q823R4 ), RNC_CHLFF (Q253V2 ), RNC_CHLMU (Q9PK97 ), RNC_CHLPN (Q9Z9C7 ), RNC_CHLSY (B9LB70 ), RNC_CHLT2 (B0B7L3 ), RNC_CHLTA (Q3KM65 ), RNC_CHLTB (B0BBS8 ), RNC_CHLTE (Q8KAN7 ), RNC_CHLTR (O84299 ), RNC_CHRVO (Q7NWC4 ), RNC_CLOAB (Q97IA4 ), RNC_CLOB8 (A6LSM2 ), RNC_CLOBA (B2V4D6 ), RNC_CLOBB (B2TJ22 ), RNC_CLOK1 (B9E1G8 ), RNC_CLOK5 (A5N807 ), RNC_CLOPE (Q8XJN8 ), RNC_CLOTE (Q895M9 ), RNC_COLP3 (Q47WP5 ), RNC_CORDI (Q6NGH3 ), RNC_COREF (Q8FP16 ), RNC_CORGL (Q8NNV6 ), RNC_CORJK (Q4JUY7 ), RNC_COXB1 (B6J4J9 ), RNC_COXB2 (B6IYZ9 ), RNC_COXBN (A9KFA0 ), RNC_COXBR (A9N942 ), RNC_COXBU (P51837 ), RNC_CUPMC (Q1LKN1 ), RNC_CUPNH (Q0K8N3 ), RNC_CUPPJ (Q46Z18 ), RNC_CUPTR (B3R1Z9 ), RNC_DECAR (Q47EF7 ), RNC_DEHM1 (Q3Z7Q8 ), RNC_DEHMC (Q3ZXY9 ), RNC_DELAS (A9BNJ5 ), RNC_DESAG (Q310Z1 ), RNC_DESPS (Q6ANV0 ), RNC_DESRM (A4J683 ), RNC_DESVH (Q72C44 ), RNC_DESVM (B8DPB3 ), RNC_DINSH (A8LLD9 ), RNC_ECO24 (A7ZQ11 ), RNC_ECO27 (B7UH07 ), RNC_ECO45 (B7MIQ2 ), RNC_ECO55 (B7LDG0 ), RNC_ECO57 (P0A7Y2 ), RNC_ECO5E (B5Z141 ), RNC_ECO7I (B7NRM0 ), RNC_ECO81 (B7MYJ8 ), RNC_ECO8A (B7M8I0 ), RNC_ECOBW (C4ZYJ0 ), RNC_ECODH (B1XB41 ), RNC_ECOHS (A8A377 ), RNC_ECOK1 (A1AE97 ), RNC_ECOL5 (Q0TES1 ), RNC_ECOL6 (P0A7Y1 ), RNC_ECOLC (B1IVR0 ), RNC_ECOLI (P0A7Y0 ), RNC_ECOLU (B7N6F5 ), RNC_ECOSE (B6I5E1 ), RNC_ECOSM (B1LP80 ), RNC_ECOUT (Q1R8G6 ), RNC_EDWI9 (C5B8Y2 ), RNC_EHRCJ (Q3YQX7 ), RNC_EHRCR (Q2GFE4 ), RNC_EHRRG (Q5FGH0 ), RNC_EHRRW (Q5HA74 ), RNC_ENT38 (A4WDD8 ), RNC_ENTFA (Q82ZG1 ), RNC_ERWT9 (B2VI46 ), RNC_ESCF3 (B7LUZ7 ), RNC_FLAPJ (A6GW45 ), RNC_FRAP2 (B0TXH8 ), RNC_FRAT1 (Q14G66 ), RNC_FRATF (A7NAR0 ), RNC_FRATH (Q2A4N2 ), RNC_FRATM (B2SFY4 ), RNC_FRATN (A0Q7W6 ), RNC_FRATO (Q0BN07 ), RNC_FRATT (Q5NER3 ), RNC_FRATW (A4IWK9 ), RNC_FUSNN (Q8RGX3 ), RNC_GEOKA (Q5L0Q3 ), RNC_GEOMG (Q39T82 ), RNC_GEOSL (Q74AX1 ), RNC_GEOSW (C5D8T6 ), RNC_GEOTN (A4IM67 ), RNC_GLOVI (Q7NH89 ), RNC_HAEDU (Q7VL75 ), RNC_HAEI8 (Q4QPN0 ), RNC_HAEIE (A5UBC4 ), RNC_HAEIG (A5UFI8 ), RNC_HAEIN (P44441 ), RNC_HAEPS (B8F3C7 ), RNC_HAHCH (Q2SL32 ), RNC_HAMD5 (C4K3Z3 ), RNC_HELAH (Q17XJ6 ), RNC_HELHP (Q7VIA9 ), RNC_HELMI (B0TGW4 ), RNC_HELP2 (B6JLQ0 ), RNC_HELPG (B5Z735 ), RNC_HELPJ (Q9ZLH2 ), RNC_HELPS (B2UTG4 ), RNC_HELPY (P56118 ), RNC_HISS2 (B0USS1 ), RNC_HUMAN (Q9NRR4 ), RNC_HYDS0 (B4U7T8 ), RNC_IDILO (Q5R106 ), RNC_IIV6 (O55748 ), RNC_JANSC (Q28V23 ), RNC_KLEP3 (B5XNH0 ), RNC_KLEP7 (A6TCI1 ), RNC_LACAC (Q5FJJ7 ), RNC_LACF3 (B2GD42 ), RNC_LACJO (Q74IP8 ), RNC_LACLA (Q9CHD0 ), RNC_LACLM (A2RLZ8 ), RNC_LACLS (Q030F9 ), RNC_LACPL (Q88WK0 ), RNC_LACRD (A5VKP2 ), RNC_LACRJ (B2G826 ), RNC_LACS1 (Q1WUA0 ), RNC_LACSS (Q38XR8 ), RNC_LEGPA (Q5X446 ), RNC_LEGPC (A5ID21 ), RNC_LEGPH (Q5ZUD5 ), RNC_LEGPL (Q5WVI4 ), RNC_LEIXX (Q6AFJ4 ), RNC_LEPBJ (Q04R64 ), RNC_LEPBL (Q053L4 ), RNC_LEPIC (Q75FW5 ), RNC_LEPIN (Q8EXX3 ), RNC_LEUCK (B1N016 ), RNC_LEUMM (Q03VW5 ), RNC_LISIN (Q92AK3 ), RNC_LISMC (C1KWA4 ), RNC_LISMF (Q71YL2 ), RNC_LISMH (B8DDU8 ), RNC_LISMO (Q8Y691 ), RNC_LISW6 (A0AJR0 ), RNC_MAGMM (A0L633 ), RNC_MANSM (Q65VN5 ), RNC_MARMS (A6VUP6 ), RNC_MESFL (Q6F1N5 ), RNC_METCA (Q608M7 ), RNC_METSB (B8EK13 ), RNC_MIMIV (Q5UQT7 ), RNC_MOOTA (Q2RJX2 ), RNC_MOUSE (Q5HZJ0 ), RNC_MYCBO (P66667 ), RNC_MYCCT (Q2SRZ8 ), RNC_MYCLE (O69469 ), RNC_MYCMO (Q6KHN3 ), RNC_MYCMS (Q6MTC9 ), RNC_MYCPA (Q73VL8 ), RNC_MYCS2 (A0QV20 ), RNC_MYCS5 (Q4A589 ), RNC_MYCTO (P9WH02 ), RNC_MYCTU (P9WH03 ), RNC_MYXXD (Q1D5X9 ), RNC_NATTJ (B2A2N1 ), RNC_NEIG1 (Q5F9X7 ), RNC_NEIG2 (B4RJT7 ), RNC_NEIM8 (C9X0M5 ), RNC_NEIMA (Q9JVD3 ), RNC_NEIMB (Q9K0C8 ), RNC_NITEC (Q0AF70 ), RNC_NITEU (Q820I0 ), RNC_NITOC (Q3J8D5 ), RNC_NITSB (A6Q1H0 ), RNC_NITWN (Q3SRB3 ), RNC_NOCFA (Q5YS08 ), RNC_OCEIH (Q8ER05 ), RNC_OENOB (Q04GL2 ), RNC_ONYPE (Q6YPW7 ), RNC_PANAM (D4GKM1 ), RNC_PARUW (Q6MEK1 ), RNC_PASMU (P57805 ), RNC_PECAS (Q6D219 ), RNC_PECCP (C6DC00 ), RNC_PEDPA (Q03FX0 ), RNC_PELCD (Q3A4Q8 ), RNC_PELLD (Q3B6L3 ), RNC_PELTS (A5D1H6 ), RNC_PELUB (Q4FLS9 ), RNC_PHEZH (B4RCU4 ), RNC_PHOLL (Q7N1X5 ), RNC_PHOPR (Q6LMS2 ), RNC_PHYMT (B3R075 ), RNC_PROMA (G3XCR8 ), RNC_PROMH (B4F047 ), RNC_PSE14 (Q48EV3 ), RNC_PSEA7 (A6VAK6 ), RNC_PSEA8 (B7UYX2 ), RNC_PSEAB (Q02HS2 ), RNC_PSEAE (Q9XCX9 ), RNC_PSEE4 (Q1I5V8 ), RNC_PSEF5 (Q4KHT1 ), RNC_PSEFS (C3K6Y7 ), RNC_PSELT (A8F397 ), RNC_PSEMY (A4XSC4 ), RNC_PSEP1 (A5W8F2 ), RNC_PSEPF (Q3KHL9 ), RNC_PSEPG (B0KV27 ), RNC_PSEPK (Q88MY5 ), RNC_PSEPW (B1J4E0 ), RNC_PSESM (Q87XG1 ), RNC_PSET1 (Q3IDL2 ), RNC_PSEU2 (Q4ZPE1 ), RNC_PSYA2 (Q4FUV6 ), RNC_PSYIN (A1SSM8 ), RNC_RALPJ (B2U981 ), RNC_RALSO (Q8Y0I1 ), RNC_RHIE6 (B3PUN8 ), RNC_RHIEC (Q2KAE3 ), RNC_RHIL3 (Q1MJ54 ), RNC_RHILO (Q985A6 ), RNC_RHILW (B5ZW73 ), RNC_RHIME (Q92R47 ), RNC_RHOBA (Q7UGZ7 ), RNC_RHOCA (Q52698 ), RNC_RHOFT (Q21XN1 ), RNC_RHOPA (Q6N6C1 ), RNC_RHOS1 (A3PGF8 ), RNC_RHOS4 (Q3J5W1 ), RNC_RHOS5 (A4WVP5 ), RNC_RHOSK (B9KSA7 ), RNC_RICAE (C3PMF3 ), RNC_RICAH (A8GM79 ), RNC_RICB8 (A8GYE2 ), RNC_RICBR (Q1RHA2 ), RNC_RICCK (A8EXI3 ), RNC_RICCN (Q92JB0 ), RNC_RICFE (Q4UKA8 ), RNC_RICM5 (A8F0M2 ), RNC_RICPR (Q9ZE31 ), RNC_RICPU (C4K1R3 ), RNC_RICRO (B0BW84 ), RNC_RICRS (A8GQT8 ), RNC_RICTY (Q68XY5 ), RNC_ROSCS (A7NGC5 ), RNC_ROSDO (Q16AI6 ), RNC_ROSHA (G2SYN4 ), RNC_ROSS1 (A5V230 ), RNC_RUEPO (Q5LNK5 ), RNC_SALCH (Q57LD0 ), RNC_SALEP (B5QTU8 ), RNC_SALG2 (B5RD49 ), RNC_SALPA (Q5PIG5 ), RNC_SALPK (B5BAT0 ), RNC_SALTI (Q8Z4K4 ), RNC_SALTY (Q56056 ), RNC_SERP5 (A8GI25 ), RNC_SHEAM (A1S3Y1 ), RNC_SHEB2 (B8EBQ2 ), RNC_SHEB5 (A3D1V6 ), RNC_SHEB8 (A6WKQ7 ), RNC_SHEB9 (A9L5N6 ), RNC_SHEDO (Q12KI1 ), RNC_SHEFN (Q07YZ6 ), RNC_SHEHH (B0TIV7 ), RNC_SHELP (A3QBS7 ), RNC_SHEON (Q8EH81 ), RNC_SHEPA (A8H1C7 ), RNC_SHEPC (A4Y4K4 ), RNC_SHEPW (B8CQJ5 ), RNC_SHESA (A0KZN2 ), RNC_SHESH (A8FSD6 ), RNC_SHESM (Q0HG98 ), RNC_SHESR (Q0HSJ1 ), RNC_SHESW (A1RMC7 ), RNC_SHEWM (B1KI57 ), RNC_SHIB3 (B2TXY0 ), RNC_SHIBS (Q31XS0 ), RNC_SHIDS (Q32CV4 ), RNC_SHIF8 (Q0T1T8 ), RNC_SHIFL (P0A7Y3 ), RNC_SHISS (Q3YYU9 ), RNC_SINFN (C3M8S4 ), RNC_SINMW (A6U7A8 ), RNC_SODGM (Q2NS13 ), RNC_SOLUE (Q027L3 ), RNC_SPHAL (Q1GTU3 ), RNC_SPICI (Q53844 ), RNC_STAA1 (A7X1J9 ), RNC_STAA2 (A6U152 ), RNC_STAA3 (Q2FHK5 ), RNC_STAA8 (Q2FZ50 ), RNC_STAA9 (A5ISB8 ), RNC_STAAB (Q2YXI3 ), RNC_STAAC (Q5HGJ9 ), RNC_STAAE (A6QGD3 ), RNC_STAAM (Q931T1 ), RNC_STAAN (P66668 ), RNC_STAAR (Q6GHK2 ), RNC_STAAS (Q6G9Y0 ), RNC_STAAT (A8Z3R9 ), RNC_STAAW (P66669 ), RNC_STACT (B9DPJ2 ), RNC_STAEQ (Q5HPV8 ), RNC_STAES (Q8CPI1 ), RNC_STAHJ (Q4L5T5 ), RNC_STAS1 (Q49X17 ), RNC_STRA1 (Q3K1Y2 ), RNC_STRA3 (Q8E680 ), RNC_STRA5 (Q8E0K7 ), RNC_STRAW (Q82JT9 ), RNC_STRCO (Q9ZBQ7 ), RNC_STRE4 (C0M8Y3 ), RNC_STRGC (A8AWC2 ), RNC_STRMU (Q8DT66 ), RNC_STRP1 (P66670 ), RNC_STRP2 (Q04K72 ), RNC_STRP3 (P0DF14 ), RNC_STRP4 (B5E4Y2 ), RNC_STRP6 (Q5XDA6 ), RNC_STRP7 (C1C7M6 ), RNC_STRP8 (P66672 ), RNC_STRPB (Q1JCZ9 ), RNC_STRPC (Q1JMX4 ), RNC_STRPD (Q1JI19 ), RNC_STRPF (Q1J7V3 ), RNC_STRPG (A2RFW8 ), RNC_STRPI (B1IC43 ), RNC_STRPJ (B8ZJR8 ), RNC_STRPM (Q48UR6 ), RNC_STRPN (Q97QG6 ), RNC_STRPQ (P0DF15 ), RNC_STRPS (B2IPN5 ), RNC_STRPZ (B5XKB7 ), RNC_STRR6 (Q8DPJ8 ), RNC_STRS7 (C0MCR4 ), RNC_STRSV (A3CP46 ), RNC_STRT1 (Q5LZ68 ), RNC_STRT2 (Q5M3S3 ), RNC_STRTD (Q03K17 ), RNC_STRU0 (B9DRH1 ), RNC_STRZJ (C1CEK4 ), RNC_STRZP (C1CKY7 ), RNC_STRZT (C1CR56 ), RNC_SULNB (A6QCJ0 ), RNC_SYMTH (Q67PF5 ), RNC_SYNFM (A0LGM1 ), RNC_SYNWW (Q0AYW0 ), RNC_THEFY (Q47S78 ), RNC_THEMA (Q9X0I6 ), RNC_THENN (B9K9K8 ), RNC_THEP1 (A5IN74 ), RNC_THESQ (B1LCY9 ), RNC_THIDA (Q3SH50 ), RNC_TREDE (Q73NX5 ), RNC_TREPA (O83787 ), RNC_TREPS (B2S448 ), RNC_TRES6 (F2NV13 ), RNC_TROW8 (Q83I82 ), RNC_TROWT (Q83FY2 ), RNC_UREPA (Q9PQT8 ), RNC_VARPS (C5CSF5 ), RNC_VEREI (A1WMW1 ), RNC_VIBA3 (B7VK79 ), RNC_VIBC3 (A5F5H8 ), RNC_VIBCB (A7MZA8 ), RNC_VIBCH (Q9KPB2 ), RNC_VIBCM (C3LR04 ), RNC_VIBPA (Q87LN9 ), RNC_VIBVU (Q8DC76 ), RNC_VIBVY (Q7MHN8 ), RNC_WIGBR (Q8D305 ), RNC_WOLPM (Q73FT3 ), RNC_WOLPP (B3CMS0 ), RNC_WOLSU (Q7M840 ), RNC_WOLTR (Q5GTI3 ), RNC_WOLWR (C0R4Q8 ), RNC_XANAC (Q8PMV0 ), RNC_XANC5 (Q3BVV6 ), RNC_XANC8 (Q4USF7 ), RNC_XANCP (Q8PB52 ), RNC_XANOR (Q5H1R2 ), RNC_XYLF2 (B2I604 ), RNC_XYLFA (Q9PB98 ), RNC_XYLFM (B0U3D8 ), RNC_XYLFT (Q87C06 ), RNC_YERE8 (A1JKK3 ), RNC_YERP3 (A7FFT9 ), RNC_YERPA (Q1C555 ), RNC_YERPE (Q8ZD72 ), RNC_YERPG (A9R402 ), RNC_YERPN (Q1CKE4 ), RNC_YERPP (A4TKX8 ), RNC_YERPS (Q667V1 ), RNC_ZUNPS (D5BDP9 ), RNC_ZYMMO (Q9Z5U2 ), RNT1_YEAST (Q02555 ), RTL1_ARATH (Q9M8N2 ), RTL2_ARATH (Q9LTQ0 ), RTL2_ORYSJ (Q6ATG6 ), RTL3_ARATH (Q9FKF0 ), RTL3_ORYSJ (Q69KJ0 ), SON_DROME (Q9VHB0 ), SON_HUMAN (P18583 ), SON_MOUSE (Q9QX47 ), STAU1_AILME (D2GVP7 ), STAU1_HUMAN (O95793 ), STAU1_MOUSE (Q9Z108 ), STAU2_DANRE (Q7ZW47 ), STAU2_HUMAN (Q9NUL3 ), STAU2_MOUSE (Q8CJ67 ), STAU2_RAT (Q68SB1 ), STAU2_XENTR (Q5M7M7 ), STAUH_APLCA (Q3L1C9 ), STAU_DROME (P25159 ), STRBP_BOVIN (Q08E27 ), STRBP_CHICK (Q5ZIL4 ), STRBP_HUMAN (Q96SI9 ), STRBP_MOUSE (Q91WM1 ), STRBP_PONAB (Q5R6Y5 ), STRBP_RAT (Q9JKU6 ), STRBP_XENLA (Q6DCD0 ), TRBP2_BOVIN (Q0IIG6 ), TRBP2_DANRE (Q7SXR1 ), TRBP2_HUMAN (Q15633 ), TRBP2_MOUSE (P97473 ), TRBP2_RAT (Q3SWU0 ), TRBP2_TETNG (Q4SS66 ), TRBP2_XENLA (Q6GPZ1 ), TRBP2_XENTR (Q5BJ52 ), YOT2_CAEEL (P34648 )» more
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| UniProtKB/Swiss-Prot False negative sequences |
58 sequences
DCL1_ASPCL (A1CBC9 ), DCL1_ASPFU (Q4WVE3 ), DCL1_ASPNC (A2RAF3 ), DCL1_ASPOR (Q2U6C4 ), DCL1_ASPTN (Q0CW42 ), DCL1_COCIM (Q1DKI1 ), DCL1_CRYPA (Q2VF19 ), DCL1_MAGO7 (A4RKC3 ), DCL1_NEOFI (A1DE13 ), DCL1_NEUCR (Q7S8J7 ), DCL1_PHANO (Q0UI93 ), DCL2_PHANO (Q0UL22 ), DCL3A_ORYSJ (Q5N870 ), DCL3B_ORYSJ (Q7XD96 ), DHX30_BOVIN (Q2NKY8 ), DHX30_CHICK (Q5ZI74 ), DHX30_HUMAN (Q7L2E3 ), DHX30_MOUSE (Q99PU8 ), DHX30_PONAB (Q5R607 ), DHX30_RAT (Q5BJS0 ), DUS2L_HUMAN (Q9NX74 ), DUS2L_MOUSE (Q9D7B1 ), HEN1_ARATH (Q9C5Q8 ), NS3B_BC133 (P0C530 ), NS3B_BCHK4 (A3EX96 ), NS3B_BCHK5 (A3EXD2 ), NSP3_ROT41 (Q3ZK63 ), NSP3_ROTAD (B3SRS1 ), NSP3_ROTAM (Q9ICB2 ), NSP3_ROTB2 (Q0H8C1 ), NSP3_ROTBN (Q65701 ), NSP3_ROTBU (P04514 ), NSP3_ROTGA (Q5K037 ), NSP3_ROTH3 (A4ZCW4 ), NSP3_ROTH6 (Q82051 ), NSP3_ROTH7 (B3SRR3 ), NSP3_ROTHD (A1YTU9 ), NSP3_ROTHK (Q82050 ), NSP3_ROTHL (A3DSK9 ), NSP3_ROTHP (B3SRV3 ), NSP3_ROTHS (Q82052 ), NSP3_ROTHT (Q82053 ), NSP3_ROTHW (Q82054 ), NSP3_ROTJ1 (Q5Y9A9 ), NSP3_ROTP5 (Q85014 ), NSP3_ROTRF (Q86504 ), NSP3_ROTRH (Q8UZL8 ), NSP3_ROTS1 (P03536 ), NSP3_ROTS4 (Q00721 ), NSP3_ROTSH (A2T3N5 ), NSP3_ROTW3 (B2BRG4 ), NSP3_ROTWI (Q82049 ), RM03_SCHPO (O43042 ), RM44_BOVIN (Q2KIS2 ), RNC_IIV3 (Q196V9 ), RNC_MYCGA (Q7NAZ2 ), RNC_MYCGF (D3FI09 ), RNC_MYCGH (D3FH24 )» more |
| UniProtKB/Swiss-Prot False positive sequences |
1 sequence
DNPEP_BOVIN (Q2HJH1 ) |
| PDB [Detailed view] |
112 PDB
1DI2; 1EKZ; 1O0W; 1QU6; 1RC7; 1STU; 1T4L; 1T4N; 1T4O; 1UHZ; 1UIL; 1WHN; 1WHQ; 1X47; 1X48; 1X49; 1YYK; 1YYO; 1YYW; 1YZ9; 2A11; 2B7T; 2B7V; 2CPN; 2DIX; 2DMY; 2EZ6; 2KHX; 2L2K; 2L2M; 2L2N; 2L33; 2L3C; 2L3J; 2LBS; 2LJH; 2LRS; 2LUP; 2LUQ; 2MDR; 2N3F; 2N3G; 2N3H; 2NA2; 2NUE; 2NUF; 2NUG; 2RS6; 2RS7; 2YT4; 3ADG; 3ADI; 3ADJ; 3ADL; 3C4B; 3C4T; 3HTX; 3J6B; 3J7Y; 3J9M; 3LLH; 3N3W; 3P1X; 3VYX; 3VYY; 4DKK; 4M2Z; 4M30; 4OOG; 4WFT; 4WYQ; 5AOR; 5B16; 5CFF; 5DV7; 5MRC; 5MRE; 5MRF; 5N8L; 5N8M; 5OC4; 5OC6; 5OOL; 5OOM; 5T16; 5ZAK; 5ZAL; 5ZAM; 5ZTM; 6EI8; 6F00; 6HTU; 6I3R; 6I9R; 6LXD; 6LXE; 6NU2; 6NU3; 6SDW; 6SDY; 6V5B; 6V5C; 6VFF; 6VLZ; 6VMI; 6ZS9; 6ZSA; 6ZSB; 6ZSC; 6ZSD; 6ZSE; 6ZSG » more |
View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission