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| Entry: PS50221 |
General information about the entry
| Entry name [info] | GPS |
| Accession [info] | PS50221 |
| Entry type [info] | MATRIX |
| Date [info] |
01-DEC-2001 CREATED;
10-MAY-2017 DATA UPDATE; 22-FEB-2023 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC50221 |
| Associated ProRule [info] | PRU00098 |
Name and characterization of the entry
| Description [info] | GPS domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=50; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=45; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.0330000; R2=0.0124252; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=3706.6765137; R2=2.0294118; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=601; H_SCORE=4926; N_SCORE=8.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=440; H_SCORE=4600; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-9; D=-20; I=-20; B1=-60; E1=-60; MI=-105; MD=-105; IM=-105; DM=-105; ... A B C D E F G H I K L M N P Q R S T V W Y Z /I: B1=0; BI=-105; BD=-105; /M: SY='N'; M=-11, 13,-24, 8, 7,-18,-14, 5,-22, 10,-22,-14, 18,-15, 3, 7, 1, 1,-22,-26, -5, 4; /M: SY='P'; M= -4,-18,-32,-12, -3,-24,-19,-18,-13,-11,-18,-13,-17, 53, -7,-18, -7, -7,-19,-29,-24, -8; /M: SY='I'; M= -9,-12,-24,-16, -5,-11,-27, -7, 6,-11, 2, 4, -9,-17, 2, -9, -8, -2, 1,-22, -3, -3; /M: SY='C'; M= -5,-19,110,-29,-28,-20,-28,-29,-28,-28,-19,-19,-19,-38,-28,-29, -8, -9, -9,-48,-29,-28; /M: SY='V'; M= 9,-18,-13,-22,-19, -9,-21,-22, 14,-15, 0, 3,-16,-22,-15,-17, -3, -1, 25,-27,-13,-18; /M: SY='F'; M=-15,-22,-26,-25,-17, 25,-23,-10, -9,-12, -2, -4,-16,-25,-14, -2,-14, -9,-10, 13, 19,-14; /M: SY='W'; M=-20,-38,-45,-40,-30, 22,-22,-28,-17,-22,-15,-17,-37,-30,-23,-20,-37,-27,-25,127, 30,-22; /M: SY='D'; M=-10, 33,-23, 34, 10,-28, -5, 1,-28, 1,-30,-23, 30,-13, 1, -4, 11, -1,-26,-39,-20, 6; /M: SY='E'; M= -9, -3,-26, -1, 13,-12,-20, 8,-17, -5,-11, -9, -5, -7, 5, -7, -3, -5,-18,-20, 1, 8; /M: SY='E'; M= -8, 4,-24, 6, 8,-17,-12, 0,-21, -2,-20,-12, 4, -6, 0, -6, 5, -1,-18,-29,-11, 3; /M: SY='D'; M= -8, 4,-25, 7, 4,-24, -5, -9,-20, 1,-18,-12, 3,-14, 2, -2, 1, -4,-15,-28,-16, 2; /I: I=-3; MD=-17; /M: SY='P'; M= 1, -3,-14, -4, -1,-12, -5, -8, -8, -4, -9, -7, -2, 5, -5, -6, -1, -2, -7,-17,-12, -4; D=-3; /I: I=-3; MI=0; MD=-17; IM=0; DM=-17; /M: SY='T'; M= -1, -1, -5, -3, -5, -4,-10, -2, -7, -8, -3, -5, 0,-11, -6, -8, 1, 3, -5,-17, -4, -6; D=-3; /I: I=-3; DM=-17; /M: SY='G'; M= -3, -7,-27, -9,-15,-25, 44,-10,-30,-16,-22,-11, 2,-19,-10,-15, -1,-15,-25,-22,-23,-13; /M: M= -6, -6,-25, -6, -4,-18, -1, -6,-18, -3,-16, -7, -5,-10, -3, -3, -3, -4,-14,-21, -8, -5; /M: SY='W'; M=-20,-40,-50,-40,-30, 10,-20,-30,-20,-20,-20,-20,-40,-30,-20,-20,-40,-30,-30,150, 30,-20; /M: SY='T'; M= -2, 11,-17, 10, 0,-21,-11,-10,-21, -2,-21,-17, 9,-11, -3, -2, 17, 20,-12,-33,-15, -2; /M: SY='T'; M= 10, -7,-17,-12, -8,-16,-12,-17,-15, -8,-17,-13, -5, -2, -7, -9, 13, 19, -8,-19,-14, -8; /M: SY='R'; M= -8, 0,-23, 1, 11,-20,-16, -5,-20, 4,-14,-11, 2,-13, 8, 13, 5, 2,-16,-28,-14, 8; /M: SY='G'; M= -2, -4,-30, -4,-17,-30, 62,-17,-39,-18,-30,-21, 4,-19,-18,-18, 0,-18,-30,-22,-29,-17; /M: SY='C'; M= -5,-20, 97,-29,-27,-18,-27,-28,-24,-28,-14,-16,-20,-36,-27,-28,-10, -9, -8,-45,-27,-27; /M: SY='Q'; M= -2, -4,-22, -4, 10,-23,-17, -7,-17, 7,-14, -8, -3,-12, 12, 6, 2, 0,-13,-25,-13, 11; /M: SY='L'; M= -3,-20,-18,-24,-18, -2,-26,-21, 12,-20, 17, 8,-20,-14,-17,-18,-10, 7, 11,-25, -7,-18; /M: SY='V'; M= -7,-16,-22,-17, -8, -9,-20,-12, 7,-13, 4, 2,-12,-21,-11, -9,-10, -7, 9,-26, -9,-11; /M: SY='E'; M= -6, -6,-27, -3, 3,-17, -3, -5,-19, -9,-17,-12, -4, -2, -5, -9, -1, -7,-18,-24,-12, -2; /M: SY='T'; M= -4, -4,-20, -4, -1,-14,-18, -9,-12, -8, -4, -7, -5, -8, -5, -4, 1, 9, -9,-28,-11, -4; /I: I=-3; MD=-14; /M: SY='N'; M= -6, 19,-20, 16, 4,-25, -3, 0,-23, -1,-26,-17, 23,-13, 6, -2, 12, 4,-22,-33,-17, 5; D=-3; /I: I=-3; MD=-14; /M: SY='E'; M= 0, -4,-23, -3, 3,-15, -9,-11,-19, 1,-14,-11, -4, -5, -4, -1, -1, -5,-14,-23,-13, -1; D=-3; /I: I=-3; MD=-14; /M: SY='T'; M= 1, 5,-18, 3, -3,-18,-12,-12,-15, -8,-16,-14, 5, 2, -6,-11, 10, 14,-12,-31,-16, -5; D=-3; /I: I=-3; MD=-14; /M: SY='H'; M=-10, -3,-23, -4, -4,-17, -9, 35,-20, -5,-18, -4, 6,-18, 2, 4, 1, -7,-16,-29, -1, -4; D=-3; /I: I=-3; MI=0; MD=-14; IM=0; DM=-14; /M: SY='T'; M= 13, -7,-11,-14,-12,-13,-10,-20, -7,-12,-11, -9, -5,-14,-12,-14, 15, 23, 5,-29,-15,-12; /M: SY='A'; M= 2,-10,-18,-14,-10,-11,-16, -7, -6, -4,-11, -5, -4,-19, -6, 2, 1, -1, 2,-25, -9, -9; /M: SY='C'; M=-10,-21,109,-30,-29,-18,-30,-29,-26,-30,-15,-17,-21,-39,-29,-29,-12,-10, -8,-48,-28,-29; /M: SY='H'; M= -8, -7,-22, -5, 3,-15,-18, 5,-13, -5, -4, -4, -4,-17, 4, 1, -2, -4,-13,-28, -7, 2; /M: SY='C'; M=-10,-18, 96,-28,-28,-15,-29,-25,-26,-27,-17,-17,-18,-37,-27,-27, -9, -5, -9,-41,-18,-28; /M: SY='N'; M= -9, 23,-21, 13, 3,-23, -9, 2,-21, 1,-24,-16, 30,-15, 6, 3, 10, 7,-23,-34,-16, 4; /M: SY='H'; M=-20, -3,-30, -3, 0,-20,-20, 69,-30, 2,-20, -3, 7,-20, 10, 22,-10,-17,-27,-27, 11, 0; /M: SY='L'; M=-10,-27,-21,-31,-21, 9,-30,-20, 22,-27, 37, 21,-25,-26,-18,-20,-24, -6, 12,-19, 1,-20; /M: SY='T'; M= 6, -3,-15, -8,-10,-18, 7,-18,-19,-12,-20,-15, 2,-12,-10,-13, 20, 23, -9,-30,-18,-10; /M: SY='S'; M= 3, 4,-15, -3, -7,-17, -4, -2,-15, -9,-20,-13, 13,-15, -6, -9, 16, 13, -9,-33,-14, -7; /M: SY='F'; M=-18,-29,-20,-37,-29, 66,-30,-18, 4,-28, 12, 2,-21,-30,-36,-19,-20, -9, 4, 6, 28,-29; /I: I=-6; MI=0; MD=-29; IM=0; DM=-29; /M: SY='A'; M= 36, -8,-12,-16,-10,-20, 6,-19,-14,-11,-14,-12, -6,-11,-10,-18, 13, 5, -4,-23,-20,-10; /M: SY='V'; M= -3,-25,-17,-29,-25, -3,-28,-25, 29,-21, 9, 14,-20,-23,-20,-21, -7, -1, 32,-27, -7,-24; /M: SY='L'; M=-11,-30,-22,-33,-23, 14,-32,-22, 24,-30, 41, 18,-27,-28,-22,-22,-27,-10, 13,-17, 3,-23; /M: SY='M'; M= -1,-22,-17,-29,-21, 4,-20,-10, 16,-14, 15, 35,-21,-22,-10,-14,-15, -7, 14,-19, -2,-15; /M: SY='D'; M= 0, 15,-22, 18, 8,-27,-12, -6,-19, -3,-19,-14, 6,-13, 4, -9, 3, -4,-13,-31,-17, 6; /M: SY='P'; M= -5,-12,-25, -9, -7,-16,-21, -7, -4,-13, -3, -1,-13, 6, -6,-15, -8, -7, -5,-28,-12, -8; /M: SY='P'; M= -5, -9,-26, -6, -4,-19,-11,-11,-13, -9,-20,-12, -7, 12, -2,-11, 4, -2,-13,-26,-12, -5; /M: SY='S'; M= 0, 6,-23, 7, 6,-26, -3, -3,-26, 1,-25,-17, 6, -6, 1, 1, 8, -3,-20,-30,-18, 2; /M: SY='H'; M=-11, -5,-25, -2, 0,-13,-19, 8,-16, -7,-13, -8, -4, -6, -3, -3, -3, -6,-12,-27, -6, -3; /I: E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
| Total number of hits | 113 in 113 different sequences |
| Number of true positive hits | 113 in 113 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 3 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 97.41 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | K_Hofmann, CJA_Sigrist |
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Feature key [info] | DOMAIN |
| Feature description [info] | GPS |
| Version [info] | 5 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
113 sequences
AGRA2_DANRE (E7FBY6 ), AGRA2_HUMAN (Q96PE1 ), AGRA2_MOUSE (Q91ZV8 ), AGRA3_DANRE (S4X0Q8 ), AGRA3_HUMAN (Q8IWK6 ), AGRA3_MOUSE (Q7TT36 ), AGRB1_HUMAN (O14514 ), AGRB1_MOUSE (Q3UHD1 ), AGRB1_RAT (C0HL12 ), AGRB2_HUMAN (O60241 ), AGRB2_MOUSE (Q8CGM1 ), AGRB2_PONAB (Q5R7Y0 ), AGRB3_HUMAN (O60242 ), AGRB3_MOUSE (Q80ZF8 ), AGRD1_BOVIN (A6QLU6 ), AGRD1_HUMAN (Q6QNK2 ), AGRD1_MOUSE (Q80T32 ), AGRD2_HUMAN (Q7Z7M1 ), AGRE1_HUMAN (Q14246 ), AGRE1_MOUSE (Q61549 ), AGRE1_RAT (Q5Y4N8 ), AGRE2_CANLF (Q2Q421 ), AGRE2_HUMAN (Q9UHX3 ), AGRE2_MACMU (Q2Q426 ), AGRE3_HUMAN (Q9BY15 ), AGRE4_HUMAN (Q86SQ3 ), AGRE4_MOUSE (Q91ZE5 ), AGRE5_BOVIN (Q8SQA4 ), AGRE5_HUMAN (P48960 ), AGRE5_MOUSE (Q9Z0M6 ), AGRF1_HUMAN (Q5T601 ), AGRF1_MOUSE (Q8VEC3 ), AGRF2_HUMAN (Q8IZF7 ), AGRF2_MOUSE (E9Q4J9 ), AGRF2_RAT (D4A3T6 ), AGRF3_HUMAN (Q8IZF5 ), AGRF3_MOUSE (Q58Y75 ), AGRF4_HUMAN (Q8IZF3 ), AGRF4_MOUSE (Q9D2L6 ), AGRF5_HUMAN (Q8IZF2 ), AGRF5_MOUSE (G5E8Q8 ), AGRF5_RAT (Q9WVT0 ), AGRG1_GORGO (Q50DM6 ), AGRG1_HUMAN (Q9Y653 ), AGRG1_MACMU (Q50DM8 ), AGRG1_MOUSE (Q8K209 ), AGRG1_PANTR (Q50DM7 ), AGRG1_PONPY (Q50DM5 ), AGRG1_RAT (Q8K3V3 ), AGRG2_HUMAN (Q8IZP9 ), AGRG2_MOUSE (Q8CJ12 ), AGRG2_RAT (Q8CJ11 ), AGRG3_HUMAN (Q86Y34 ), AGRG3_MOUSE (Q8R0T6 ), AGRG4_HUMAN (Q8IZF6 ), AGRG4_MOUSE (B7ZCC9 ), AGRG5_HUMAN (Q8IZF4 ), AGRG5_MOUSE (Q3V3Z3 ), AGRG6_DANRE (C6KFA3 ), AGRG6_HUMAN (Q86SQ4 ), AGRG6_MOUSE (Q6F3F9 ), AGRG7_HUMAN (Q96K78 ), AGRG7_MOUSE (Q8BM96 ), AGRL1_BOVIN (O97831 ), AGRL1_HUMAN (O94910 ), AGRL1_MOUSE (Q80TR1 ), AGRL1_RAT (O88917 ), AGRL2_BOVIN (O97817 ), AGRL2_HUMAN (O95490 ), AGRL2_MOUSE (Q8JZZ7 ), AGRL2_RAT (O88923 ), AGRL3_BOVIN (O97827 ), AGRL3_HUMAN (Q9HAR2 ), AGRL3_MOUSE (Q80TS3 ), AGRL3_RAT (Q9Z173 ), AGRL4_DANRE (Q7SY09 ), AGRL4_HUMAN (Q9HBW9 ), AGRL4_MOUSE (Q923X1 ), AGRL4_RAT (Q9ESC1 ), AGRV1_DANRE (Q6JAN0 ), AGRV1_HUMAN (Q8WXG9 ), AGRV1_MOUSE (Q8VHN7 ), CELR1_HUMAN (Q9NYQ6 ), CELR1_MOUSE (O35161 ), CELR2_HUMAN (Q9HCU4 ), CELR2_MOUSE (Q9R0M0 ), CELR2_RAT (Q9QYP2 ), CELR3_HUMAN (Q9NYQ7 ), CELR3_MOUSE (Q91ZI0 ), CELR3_RAT (O88278 ), CELR_CAEEL (G5EDK5 ), LPHN_DROAN (B3MFV7 ), LPHN_DROER (B3N8M1 ), LPHN_DROGR (B4J780 ), LPHN_DROME (A1Z7G7 ), LPHN_DROMO (B4KMZ1 ), LPHN_DROPE (B4GD14 ), LPHN_DROPS (Q292N4 ), LPHN_DROSE (B4HS00 ), LPHN_DROVI (B4LNA8 ), LPHN_DROYA (B4P3A0 ), LPLT1_CAEEL (G5EDW2 ), LPLT2_CAEEL (G5ECX0 ), PK1L1_ORYLA (E7FKV8 ), PK1L2_HUMAN (Q7Z442 ), PK1L2_MOUSE (Q7TN88 ), PK1L3_HUMAN (Q7Z443 ), PK1L3_MOUSE (Q2EG98 ), PK1L_ACRMI (B8UU59 ), PKD1_HUMAN (P98161 ), PKD1_MOUSE (O08852 ), STAN_DROME (Q9V5N8 ), SUREJ_STRPU (Q26627 )» more
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| UniProtKB/Swiss-Prot False negative sequences |
3 sequences
PK1L1_HUMAN (Q8TDX9 ), PK1L1_MOUSE (Q8R526 ), PKD1_CAEEL (Q09624 ) |
| PDB [Detailed view] |
22 PDB
4DLO; 4DLQ; 5KVM; 6VHH; 7D76; 7D77; 7QU8; 7WU3; 7WU4; 7WU5; 7WUI; 7WXU; 7WXW; 7WY0; 7WY5; 7WY8; 7WYB; 7WZ7; 7X10; 7X2V; 7XKE; 7YP7 » more |
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