PROSITE entry PS50221
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General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS50221 |
| Entry name [info] | GAIN_B |
| Accession [info] | PS50221 |
| Entry type [info] | MATRIX |
| Date [info] |
01-DEC-2001 CREATED;
29-MAY-2024 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC50221 |
| Associated ProRule [info] | PRU00098 |
Name and characterization of the entry
| Description [info] | GAIN-B domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=159; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=154; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.9929707; R2=0.0094988; TEXT='-LogE'; /CUT_OFF: LEVEL=0; SCORE=1054; N_SCORE=12.0; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=475; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-27; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='P'; M= -64, -83, -9, 23, -1, -70, 23, -75, -11, -74, -3, -12, 72, 38, 6, 9, -4, -75, 13, -16; /M: SY='Y'; M= -8, -74, -65, -25, 15, -70, -5, 15, -35, -42, 14, 15, 0, 4, 18, 27, 15, -3, -71, 28; /M: SY='L'; M= -35, 27, -69, 6, 29, -76, -68, -13, -65, 38, 2, -5, -76, -65, -10, 17, 23, 6, -76, -57; /M: SY='Q'; M= -18, -73, 4, -5, -8, -68, 22, -30, -29, -65, -7, 13, -70, 41, -20, 31, 36, 9, -77, 19; /M: SY='L'; M= -19, -73, -81, -75, 25, -82, -75, 44, -75, 46, -9, -75, -2, -27, -76, -33, 19, 13, -74, -55; /M: SY='S'; M= 17, -72, -25, -12, -74, 8, 24, 3, -7, -45, -15, -26, -6, -17, -64, 59, -1, -23, -83, -67; /M: SY='S'; M= 21, -73, -62, -9, -21, -63, -64, -37, -11, -47, -64, 2, 25, 31, -10, 49, 17, -17, 22, -25; /M: SY='E'; M= -23, -10, -3, 36, -78, 1, 23, -38, 28, -77, -69, 15, 25, 20, -5, 18, -11, -74, -81, -14; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='N'; M= 5, -73, 8, -27, -75, -36, -4, -69, -32, -73, 16, 73, -19, 10, 5, 23, 7, -16, 17, -68; /M: SY='V'; M= -7, -73, -79, -72, 0, -81, -71, 35, -71, 37, -43, -74, -79, 22, -38, -66, 8, 39, -71, 23; /M: SY='Q'; M= 19, -14, -23, 6, -7, -65, -63, -62, -26, -9, -61, 12, -21, 37, -30, 36, 29, -1, -81, -65; /M: SY='M'; M= -28, -74, -77, -5, -19, -81, -71, 27, -41, 41, 63, -75, 15, -67, -34, -17, -60, 28, -77, -60; /M: SY='S'; M= -56, -73, -51, 39, -79, -19, -58, -76, 21, -43, -69, 37, -66, 34, -23, 55, 23, -71, -83, -70; /M: SY='V'; M= -30, 3, -30, -73, -57, -18, -73, 21, -72, 17, 24, -20, -77, -70, -75, 24, -25, 58, -82, -16; /M: SY='P'; M= -6, -16, -60, 12, 9, -67, -1, -34, -24, -66, 32, 14, 37, 36, -31, 26, 27, -65, 4, -9; /M: SY='H'; M= 12, -74, -5, 15, -18, -5, 35, -14, 8, -29, -61, 20, -6, -57, -26, 8, 9, 12, -83, -65; /M: SY='L'; M= -36, -74, -68, -13, 12, -41, -5, 16, -1, 36, -6, 20, -35, 9, -65, 3, -7, 1, -74, -13; /M: SY='E'; M= -20, -76, 4, 39, -21, -39, 5, -39, 17, -27, -3, -4, 21, -10, -6, 31, 12, -39, -82, -66; /M: SY='P'; M= 6, -9, 23, -19, -26, -33, -5, -70, -14, -12, -65, 26, 45, -14, -10, 11, 34, -67, -82, -20; /M: SY='T'; M= 18, -73, -4, -13, -73, -8, -2, -11, 25, -68, -14, 6, -69, -9, -4, 25, 26, 3, 26, -66; /M: SY='N'; M= 9, -5, -24, 6, -72, 10, 14, -38, -30, -14, -62, 43, -16, -11, -65, 15, 26, 10, -86, -69; /I: I=-12; MI=0; MD=-30; IM=0; DM=-30; /M: SY='N'; M= -24,-101, -82, -7,-100, -29, 14, -55, -83, -99, -92, 33, -99, -83, -17, -42, 4, -28,-112, -33; D=-12; /I: I=-12; DM=-30; /M: SY='H'; M= -27, -97, -9, -78, -89, -45, 18, -12, -36, -26, -78, 10, -5, 12, -14, -32, -33, -17, 15, -83; D=-12; /I: I=-12; DM=-30; /M: SY='Q'; M= 15, -89, -41, -77, -1, -20, -79, -46, -74, -82, -78, 8, -3, 15, -8, 13, -71, -3, -91, -19; D=-12; /I: I=-12; DM=-30; /M: SY='G'; M= -26, -85, -73, -3, -74, 21, -72, -44, -67, 20, -9, -17, -31, 20, 14, -8, -10, -42, -85, -19; D=-12; /I: I=-12; DM=-30; /M: SY='D'; M= 27, -79, 32, -62, -40, -5, -12, -76, -66, -30, -72, 23, 30, -17, -34, 23, -25, -39, -88, -30; D=-12; /I: I=-12; DM=-30; /M: SY='S'; M= -27, -78, -66, -62, -71, -19, 2, -71, -9, -75, -68, -3, -14, 14, 41, 44, 18, -5, 20, 19; D=-12; /I: I=-12; DM=-30; /M: SY='M'; M= -36, -74, -16, -75, 17, -82, -73, 56, -70, -23, 76, -72, -76, -70, -7, -31, -9, 42, -77, -56; /M: SY='Q'; M= -12, -75, 3, 21, -17, -72, -62, -28, -4, -20, -10, 0, -72, 38, 27, 5, 0, 28, -79, -16; /M: SY='L'; M= -67, -75, -81, -74, 27, -85, -12, 43, -74, 56, -40, -76, -25, 23, -74, -35, -16, 5, -72, -53; /M: SY='P'; M= -30, -87, -9, -56, -86, -20, -8, -77, -33, -84, -72, -24, 109, -13, -32, -4, -27, -79, -83, -80; /M: SY='W'; M= -10, 35, -65, 3, -69, -38, 22, -69, 10, -47, -65, -13, 40, 13, 20, -6, -5, -4, 81, -14; /M: SY='T'; M= 22, -73, 26, 2, -2, 0, -5, -72, -4, -46, 1, -2, -22, -14, 7, 23, 33, -67, -81, -65; /I: I=-20; MD=-51; /M: SY='L'; M= -1, -76, -8, -13, -20, -40, 4, 4, -28, 37, -14, -68, -2, -2, -38, 11, -33, 11, -81, -63; D=-20; /I: I=-20; MD=-51; /M: SY='F'; M= -11, -76, -81, -78, 47, -27, -8, 20, -44, 38, -14, -2, -83, -75, -32, -70, -10, 11, -73, -53; D=-20; /I: I=-20; MD=-51; /M: SY='W'; M= -1, -84, -25, 20, -7, -17, -12, -19, -3, -49, -70, -69, -79, -5, -24, 23, -34, 10, 45, -69; D=-20; /I: I=-20; MI=0; MD=-51; IM=0; DM=-51; /M: SY='P'; M= -47, -88, -11, -12, 1, -19, -1, -39, 18, -27, -6, -28, 28, 15, -9, 13, -68, -45, -84, -19; D=-20; /I: I=-20; DM=-51; /M: SY='P'; M= 18, -81, -65, 10, -80, -10, -18, -33, -36, -11, -67, 30, 39, 7, -31, -11, -11, -17, -88, -76; D=-20; /I: I=-20; DM=-51; /M: SY='S'; M= -16, -79, 16, -11, -80, -9, -16, -39, -32, -34, -70, 17, 40, -27, -38, 41, 1, -3, -90, -75; D=-20; /I: I=-20; DM=-51; /M: SY='H'; M= -31, -79, 22, 31, -76, -69, 37, -72, -22, -8, -64, 37, 32, 11, 33, 2, -13, -39, -86, -67; /M: SY='S'; M= 10, -73, -23, -8, -28, -19, -62, -72, 4, -75, -68, 15, 23, 18, -1, 57, 8, -23, -82, -69; /M: SY='G'; M= 4, -76, 25, -39, -75, 63, -66, -73, -65, -16, -1, -4, 4, 2, -71, 10, -24, -38, -79, -20; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='D'; M= 6, 24, 31, 24, -68, -17, 27, -30, -62, -2, -61, -5, 27, -60, -29, -8, -60, 16, 18, -16; /M: SY='S'; M= -20, 27, -68, -16, 23, -72, 1, -54, -2, -1, -56, -62, -18, -18, -27, 33, 30, 23, -72, 24; /M: SY='R'; M= -10, -75, -30, -57, -70, -12, -7, -30, 28, -22, -59, -58, -72, 31, 45, 4, 24, 21, -79, -16; /M: SY='V'; M= 15, -72, -79, -73, -56, -79, -76, 49, -73, 31, -43, -16, -26, 7, -75, -65, -25, 49, -80, -63; /M: SY='Q'; M= -2, -75, -69, -67, -4, 15, 22, 38, -66, -11, -53, 23, -74, 38, -69, -31, 9, 20, 17, -60; /M: SY='F'; M= -24, -10, -75, -15, 74, -40, -1, -9, -70, 10, -52, -18, -80, -71, -27, -5, -26, 12, -59, 39; /M: SY='T'; M= -39, -72, -75, -73, -13, -78, -72, 28, -71, 38, 28, -9, -14, -69, -74, 1, 40, 22, 25, -24; /M: SY='W'; M= 29, -15, -12, -9, 16, -68, -70, -10, -24, 3, -57, -64, -73, -62, -23, 35, -7, 9, 66, -18; /M: SY='Y'; M= -71, -77, -22, -76, 81, -38, -58, -11, -73, -5, -53, -18, -26, -73, -72, -18, -13, -57, -46, 81; /M: SY='P'; M= -21, -79, 19, 15, -34, -7, 36, -77, -6, -54, -68, 38, 41, 6, 29, 9, -22, -43, -84, -67; /M: SY='N'; M= 4, -70, -54, -22, -77, -5, 1, -74, -10, -77, -69, 61, -26, -15, -13, 45, 49, -68, -87, -70; /I: I=-45; MD=-115; /M: SY='M'; M= -42, -77, -76, -13, -1, -21, 1, 16, -68, 43, 45, -72, -38, 15, -3, -69, 2, -10, -78, -59; D=-45; /I: I=-45; MI=-115; IM=-115; DM=-115; /M: SY='G'; M= -15, -77, -8, 3, -70, 57, 32, -68, -62, -40, -65, 3, -72, 21, -26, -27, -10, 9, 17, 14; /M: SY='W'; M= 0, -75, 12, -63, -17, -21, -7, -56, 2, 40, -5, 5, -34, 4, -23, -13, -28, -32, 48, 22; /M: SY='F'; M= -67, -75, -81, -75, 66, -42, -70, 40, -72, 39, -44, -74, -81, 17, -31, -8, -22, -21, -63, -8; /I: I=-10; MD=-24; /M: SY='L'; M= -35, -79, -79, -27, 5, -85, -1, -8, -2, 58, -7, -77, -28, 13, -2, -74, -68, -27, -74, -6; D=-10; /I: I=-10; MD=-24; /M: SY='P'; M= -12, -89, 5, 7, -92, -19, -74, -33, 0, -89, -80, 11, 67, -67, -73, 5, -9, -81, -94, -86; D=-10; /I: I=-10; MD=-24; /M: SY='P'; M= -11, -88, -70, 2, -26, -48, 17, -76, -34, -46, -74, 12, 69, -16, -76, -19, 3, -12, -92, -79; D=-10; /I: I=-10; MD=-24; /M: SY='S'; M= 11, -84, -70, 15, -88, -2, -77, -39, -33, -56, -78, -4, -80, -19, -27, 28, 26, -40, -95, -83; D=-10; /I: I=-10; MD=-24; /M: SY='P'; M= -21, -94, 2, -80, 30, -17, -78, -39, -83, -22, -76, -7, 36, -22, -87, -15, -77, -80, -79, 31; D=-10; /I: I=-10; MD=-24; /M: SY='N'; M= -52, -92, 4, -78, 7, -88, -77, -75, -80, 8, -72, 24, 19, 1, -85, -30, 2, -46, -88, 13; D=-10; /I: I=-10; MD=-24; /M: SY='S'; M= -24, -94, -27, -13, -11, -46, -17, -86, -76, -26, -82, -3, -2, 7, -6, 9, -1, -47, -99, -83; D=-10; /I: I=-10; MI=0; MD=-24; IM=0; DM=-24; /M: SY='W'; M= 3, -98, -9, 4, -97, -4, -4, -94, -8, -50, -88, -15, -91, -27, -7, -18, -81, -40, 13, -88; D=-10; /I: I=-10; DM=-24; /M: SY='Q'; M= -23, -95, -17, -3, -88, -9, -78, -14, -37, -36, -13, -9, 17, 22, -19, 4, -75, -81, -94, -15; D=-10; /I: I=-10; DM=-24; /M: SY='D'; M= -18, -89, 33, -16, -83, -39, -14, -20, -67, -20, -74, 23, -35, 22, 6, -31, -13, -32, -95, -19; D=-10; /I: I=-10; DM=-24; /M: SY='P'; M= -20, -88, -10, -36, -85, 1, -10, -38, 3, -29, -75, 11, 39, 11, -71, 4, -4, -44, 16, -79; D=-10; /I: I=-10; DM=-24; /M: SY='N'; M= -16, -85, -64, -18, -9, 5, -68, -85, 1, -86, -78, 53, 11, 1, 14, 17, -65, -48, -89, -77; D=-10; /I: I=-10; DM=-24; /M: SY='E'; M= -44, -4, -11, 28, -83, -1, -69, -75, 13, -31, -72, 19, -24, 0, 16, -39, 14, -6, -91, -78; D=-10; /I: I=-10; DM=-24; /M: SY='N'; M= -69, -85, -26, 1, -78, -44, 18, -80, -2, -18, -71, 39, 14, 21, 20, 19, -20, -80, -86, 5; D=-10; /I: I=-10; DM=-24; /M: SY='R'; M= -46, -82, -70, -18, -71, -78, -67, -28, -11, 16, -8, 19, 13, 5, 33, 7, 5, -23, -85, -18; D=-10; /I: I=-10; DM=-24; /M: SY='T'; M= -19, 30, -75, -34, -1, 1, -76, -16, -17, -32, -63, -68, -2, -30, -10, -1, 36, 27, -83, -19; D=-10; /I: I=-10; DM=-24; /M: SY='V'; M= -19, -75, -82, -78, -22, -83, -75, 12, -29, 42, 22, -12, -83, -73, -76, -8, -27, 43, -81, -17; D=-10; /I: I=-10; DM=-24; /M: SY='N'; M= 15, -71, 2, -10, -70, -21, -58, -24, -26, -27, -8, 75, -23, -57, -64, 11, 17, -4, -84, -8; D=-10; /I: I=-10; DM=-24; /M: SY='S'; M= 1, -67, -21, 11, -76, 13, -61, -74, -57, -77, -70, 16, -65, -52, -64, 80, 36, -67, -84, -70; /M: SY='P'; M= -63, -80, 12, -53, -63, -16, -13, -26, 16, -5, -59, -18, 49, 44, 36, 0, -26, -68, -69, 43; /M: SY='V'; M= -57, -70, -83, -77, -54, -47, -80, 37, -71, -12, -1, -77, -79, -74, -2, -68, -55, 86, -82, -15; /M: SY='I'; M= -62, -74, -79, -77, -18, 0, -72, 59, -70, 12, 47, -23, -15, -70, -9, -68, -59, 45, -73, 7; /M: SY='S'; M= 3, -70, -63, -65, -20, 21, 3, -11, -61, -66, -12, -6, -70, -57, -22, 69, -3, -19, -69, 47; /M: SY='A'; M= 40, -3, -74, -69, -59, -5, -71, -2, -68, 25, -3, -68, 9, -67, -31, -20, 6, 35, -76, -2; /M: SY='S'; M= 19, -70, -60, 9, -6, 4, -64, -12, -23, -68, -64, -54, -67, 2, 8, 63, 18, -10, -78, -64; /M: SY='V'; M= -61, 8, -82, -76, -51, -84, -77, 54, -75, 44, -2, -76, -79, -6, -76, -28, -23, 54, -79, -59; /M: SY='S'; M= -58, -74, -4, -7, -23, 17, -8, -37, -25, 3, -60, 17, 0, 7, 11, 37, 16, -36, -73, 27; /I: I=-18; MD=-45; /M: SY='N'; M= -17, -78, 23, 5, -82, 25, 33, -82, -2, -82, -72, 59, 32, 10, -2, 8, -58, -79, -86, -71; D=-18; /I: I=-18; MI=0; MD=-45; IM=0; DM=-45; /M: SY='P'; M= -32, 26, 18, -12, 9, -45, -71, -37, -15, -49, 7, -24, 46, -5, 1, 14, 2, -74, -86, -71; D=-18; /I: I=-18; DM=-45; /M: SY='W'; M= -64, -81, -69, -36, -75, 16, -7, -26, -14, -17, -65, -1, 26, 31, 0, -1, 28, -1, 34, -70; D=-18; /I: I=-18; DM=-45; /M: SY='T'; M= -36, -77, -65, -12, -72, -74, -13, 5, 3, -21, -2, 17, 8, 5, 6, 18, 35, 12, -87, -69; D=-18; /I: I=-18; DM=-45; /M: SY='R'; M= -4, -80, -66, 3, -14, 14, -68, -38, 14, -10, -63, -27, 10, 18, 31, -31, 4, -8, 23, -67; D=-18; /I: I=-18; DM=-45; /M: SY='N'; M= -3, -75, 17, 6, -8, -35, 23, -69, -11, -40, -65, 62, 11, -21, -62, 1, 8, -23, -78, 28; D=-18; /I: I=-18; DM=-45; /M: SY='L'; M= -36, -72, -70, -4, -15, -20, -66, -45, -65, 64, -42, -20, 7, 7, -17, -19, 17, -14, -75, -59; /M: SY='S'; M= 22, -69, 26, -7, -71, -34, -5, -39, -28, 3, -15, 15, -68, 16, -62, 54, 14, -33, -83, -66; /M: SY='D'; M= -34, -76, 50, 28, -79, -30, -15, -72, 28, -74, -7, 26, 1, 16, 7, 25, -24, -10, -85, -68; /M: SY='P'; M= -13, -81, -18, 12, -36, -34, -64, -72, -36, -29, -67, 28, 98, -10, -67, 6, -22, -73, -81, -75; /M: SY='V'; M= -32, -72, -83, -77, -17, -84, -77, 57, -75, -16, 31, -77, -78, -20, -76, -69, -56, 74, -75, 16; /M: SY='T'; M= -33, -71, -12, 0, -31, -71, 3, 33, -28, -4, -54, 28, -69, -16, 2, -7, 61, -33, -77, 13; /M: SY='Y'; M= -65, -73, -83, -79, 47, -85, -67, 36, -76, 36, 0, -79, -82, -74, -75, -72, -61, 46, -59, 59; /M: SY='T'; M= -23, -71, -21, 21, -36, -36, 23, -3, -8, -67, -62, 10, -65, 25, -2, 33, 62, -32, -83, -64; /M: SY='F'; M= -68, -72, -86, -80, 71, -85, -69, 15, -78, 55, 21, -80, -84, -77, -76, -75, -63, 20, -59, 13; /I: I=-13; MD=-32; /M: SY='Q'; M= -14, -79, -3, 8, -31, -70, -61, -75, 26, -74, -68, -56, -71, 42, 41, 28, 20, -38, 40, 6; D=-13; /I: I=-13; MD=-32; /M: SY='H'; M= -38, -85, -27, -65, -3, -78, 112, -11, -4, -17, -61, -27, -79, -60, -22, 5, -69, -74, -90, -11; D=-13; /I: I=-13; MD=-32; /M: SY='H'; M= -37, -82, -30, -8, -19, -84, 57, 32, -16, 14, -5, -29, -79, -29, -26, -69, 19, -5, 20, -61; D=-13; /I: I=-13; MD=-32; /M: SY='Q'; M= -8, -83, -62, 36, 2, -77, -66, -37, 8, -25, -69, 9, -34, 39, 15, 1, -14, -40, -84, -70; D=-13; /I: I=-13; MD=-32; /M: SY='P'; M= -26, -84, -1, -6, -83, -18, 1, -77, -12, -55, -12, 11, 40, 30, -22, 4, 26, -39, -89, -25; D=-13; /I: I=-13; MD=-32; /M: SY='W'; M= -41, -91, 11, -2, -87, -81, -79, -20, -6, -55, -80, -70, -8, 16, -28, 36, -13, -39, 53, -78; D=-13; /I: I=-13; MI=0; MD=-32; IM=0; DM=-32; /M: SY='N'; M= -11, -85, -17, -2, -89, 32, 20, -38, 18, -87, -77, 35, 33, -17, -66, -3, -66, -82, -90, -79; D=-13; /I: I=-13; DM=-32; /M: SY='R'; M= -25, -75, -15, -30, -16, 15, -14, -60, -15, -4, 17, 10, 2, -57, 48, -8, 22, 3, 29, -15; D=-13; /I: I=-13; DM=-32; /M: SY='H'; M= -8, -74, -1, -3, -8, -17, 53, -30, -6, -21, -58, -55, -27, 35, -26, 28, 24, -2, -74, 26; D=-13; /I: I=-13; DM=-32; /M: SY='W'; M= -61, -75, 24, 22, -25, -67, -4, -34, 26, -44, -64, 38, -67, 17, -6, 10, 41, -36, 53, -5; D=-13; /I: I=-13; DM=-32; /M: SY='P'; M= 2, -74, -68, -62, -67, -68, 17, -5, -20, 13, -55, -63, 74, -62, -68, 35, 17, 9, -81, -67; D=-13; /I: I=-13; DM=-32; /M: SY='Q'; M= -63, -76, -66, -21, -4, -11, 42, 28, 0, 20, 0, -28, -73, 52, -6, -34, 1, -8, -71, 20; D=-13; /I: I=-13; DM=-32; /M: SY='C'; M= -15, 149, -81, -80, -73, -76, -81, -78, -77, -70, -70, -68, -22, -83, -83, -63, -62, -66,-100, -83; D=-13; /I: I=-13; DM=-32; /M: SY='V'; M= 41, -67, -75, -68, -17, -70, -70, -34, -68, 12, -46, -28, -75, 11, -69, -34, -53, 72, -74, 16; /M: SY='F'; M= -68, -74, -77, -73, 96, -41, 17, -55, -67, -9, -52, -68, -80, -20, -4, 13, -63, -59, 46, 55; /M: SY='W'; M= -75, -96, -99, -79, 24, -75, -93, -69, -72, -41, -69, -92, -20, -73, -75, -80, -83, -81, 171, 10; /M: SY='N'; M= -62, -75, 75, 26, -81, -60, -3, -79, 11, -80, -73, 77, -17, 0, -54, -3, -53, -49, -92, -69; /M: SY='H'; M= -34, -76, -3, 35, 36, -19, 53, -67, 12, -20, -6, -55, 1, 23, -23, 18, -21, -67, -65, 38; /M: SY='S'; M= 5, -72, 34, 0, -27, -37, 18, -40, -18, -44, -19, 9, 4, 13, 21, 49, 12, -66, -79, -15; /M: SY='E'; M= 5, -73, -2, 31, -72, 6, -15, -34, 1, -13, 1, 2, 16, 30, -12, 19, 7, -6, -79, -66; /I: I=-29; MD=-75; /M: SY='Q'; M= -3, -98, -1, -16, -34, -21, -84, -95, -80, -34, -88, 6, -2, 16, -43, 7, -79, -93,-104, -91; D=-29; /I: I=-29; MI=0; MD=-75; IM=0; DM=-75; /M: SY='H'; M= -85, -12, -28, -38, -33, -1, 19, -93, -85, -26, -6, -8, -97, 4, -49, -4, -4, -93, 7, -85; D=-29; /I: I=-29; DM=-75; /M: SY='G'; M= -54, -77, -13, -12, -77, 84, -13, -80, -28, -37, 24, -18, -69, -21, -29, -2, -65, -77, 22, -71; D=-29; /I: I=-29; DM=-75; /M: SY='H'; M= -7, -74, -5, -31, -69, 39, 47, -32, -19, -39, 21, -53, -69, 27, -5, 23, 17, -7, -77, 4; D=-29; /I: I=-29; DM=-75; /M: SY='W'; M= -74, -15,-100, -80, -3, -73, -99, -72, -72, -70, -73, -92, -79, -72, -75, -35, -84, -85, 175, -28; /M: SY='S'; M= -2, -69, 51, -49, -76, -57, -57, -72, 5, -45, -68, 35, -66, -8, 2, 64, 31, -67, -85, -67; /M: SY='T'; M= 5, -67, 5, -25, -72, -60, -62, -66, -54, -22, -63, -15, 24, -8, 5, 60, 64, -61, -83, -67; /M: SY='E'; M= -40, -76, 56, 59, -78, -66, -3, -77, -27, -34, -68, 4, -64, 29, 27, 31, -5, -72, -84, -67; /M: SY='G'; M= -30, -77, -25, -72, -26, 97, -69, -87, -66, -83, -74, -16, -21, -66, -23, -50, -67, -82, -74, -74; /I: I=-42; MI=0; MD=-106; IM=0; DM=-106; /M: SY='C'; M= -28, 147, -81, -80, -17, -76, -79, -29, -76, -35, 7, -68, -89, -82, -82, -64, -61, -61, -94, -75; /M: SY='Q'; M= -12, -74, -56, 25, -26, -67, -13, -28, 30, -36, -59, -54, -67, 47, 36, 36, 2, -14, -70, 27; /M: SY='V'; M= -15, -70, -75, -69, -54, -77, 17, 1, -68, 44, 21, -70, 37, -67, -25, -62, 26, 49, -79, -59; /I: I=-20; MD=-51; /M: SY='V'; M= -30, -72, -66, 18, -62, 0, 18, 22, -18, 10, -3, -64, -71, 13, -25, -7, 6, 47, -81, -62; D=-20; /I: I=-20; MD=-51; /M: SY='H'; M= -9, -79, 16, 49, -29, -14, 64, -38, -23, -49, -64, -26, 36, 4, -3, 5, -20, -71, -77, 17; D=-20; /I: I=-20; MD=-51; /M: SY='S'; M= -14, -73, 19, 24, -74, 19, -11, -68, -15, -11, -64, -12, -3, -9, 12, 41, 17, -16, -82, -68; D=-20; /I: I=-20; MD=-51; /M: SY='N'; M= -61, -74, 38, -55, -76, -36, -56, -14, -28, -76, -69, 75, -71, 27, -36, 28, 35, -70, -88, -13; D=-20; /I: I=-20; MI=0; MD=-51; IM=0; DM=-51; /M: SY='P'; M= 21, -73, 24, -7, -71, -1, -61, -13, -4, -8, 20, 32, 46, 1, -31, -4, 0, -29, -80, -68; /M: SY='S'; M= -30, -68, 21, -19, -73, -3, 0, -36, -53, -45, -65, 44, -65, -1, -3, 62, 49, -65, -85, -66; /M: SY='H'; M= -31, -75, -60, -14, 9, -70, 86, -2, -5, -38, -10, -17, -70, 46, -7, 8, 17, -31, -67, 50; /M: SY='T'; M= 17, -63, -64, -64, -65, -34, -71, -46, -62, -34, -55, -55, -65, -63, -68, 20, 84, 46, -85, -65; /M: SY='T'; M= -10, -69, -59, -7, -22, -67, 15, 15, 3, -39, -7, 34, -69, 16, -6, 22, 36, 34, -81, -61; /M: SY='C'; M= -61, 150, -81, -81, -69, -77, -80, -72, -77, -22, -65, -68, -91, -84, -83, -64, -61, -30, -99, -79; /M: SY='S'; M= -7, -73, -29, -19, -19, -67, 18, -12, -8, 23, -53, -20, -71, 42, 44, 45, -32, -59, -74, -11; /M: SY='C'; M= -61, 147, -78, -78, -66, -76, -76, -75, -74, -67, -67, -65, -87, -80, -80, -61, 16, -64, -90, 15; /M: SY='N'; M= -58, -71, 32, -51, -6, -59, 44, -74, -49, -74, -66, 77, -69, 32, 13, 39, 26, -72, -86, -61; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='H'; M= -38, -80, -56, -54, -26, -71, 138, -80, -53, -67, -55, -46, -71, -48, 31, -25, -65, -38, -95, -40; /M: SY='L'; M= -65, -69, -83, -76, 3, -83, -68, 2, -76, 81, 38, -79, -81, -70, -74, -32, -27, -20, -70, -52; /M: SY='T'; M= -8, -63, -57, -60, -71, 1, -65, -65, -23, -69, -63, -10, -61, -58, -63, 50, 93, -57, -85, -67; /M: SY='S'; M= 17, -68, -58, -61, 10, -34, 59, -31, -60, -64, 8, 41, -15, -55, -63, 61, 6, -10, -77, -1; /M: SY='F'; M= -74, -72, -85, -82, 113, -82, -63, -48, -77, -10, -49, -77, -85, -84, -74, -73, -66, -27, -40, 50; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='A'; M= 75, -65, -64, -28, 10, 11, -67, -36, -25, -67, -63, -57, -66, -58, -65, 41, -15, -57, -73, -64; /M: SY='I'; M= -59, -71, -84, -80, -50, -87, -82, 72, -77, 19, 10, -78, -77, -75, -78, -71, -55, 69, -79, -58; /M: SY='L'; M= -66, -70, -80, -34, 24, -30, -68, -1, -75, 78, -33, -79, -82, -16, -73, -73, -63, 0, -67, -8; /M: SY='M'; M= 6, -70, -77, -67, -56, -72, -59, -39, -63, -5, 121, -69, 14, 11, -20, -31, -57, 23, -76, -56; /M: SY='D'; M= 26, -75, 54, -2, -15, -62, -58, -72, -51, -44, -66, -9, 38, 46, 21, 30, -54, -44, -80, -66; /M: SY='P'; M= -18, -73, -17, -58, -64, -68, 28, 3, -23, 24, -7, 29, 49, 31, -63, 17, -4, 10, -80, -62; /M: SY='S'; M= -3, -76, -3, -61, -33, -31, -5, 1, -29, -36, -62, 17, 43, -7, -15, 45, -11, -19, -74, 33; /M: SY='H'; M= -36, -83, 26, 5, -82, -15, 48, -80, -5, -48, -21, -16, 17, -9, 41, 10, 0, -49, -90, -70; /M: SY='V'; M= -5, -80, 5, 2, -1, -77, -14, -8, -27, -11, -63, -67, 10, -3, -11, 19, -10, 22, -86, -68; /M: SY='E'; M= -23, -83, 13, 37, -80, -34, -13, -26, -61, -29, -70, -16, 26, 21, -23, 27, -5, -30, -88, -28; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 116 in 116 different sequences |
| Number of true positive hits | 116 in 116 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | GAIN-B |
| Version [info] | 6 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
116 sequences
AGRA2_DANRE (E7FBY6), AGRA2_HUMAN (Q96PE1), AGRA2_MOUSE (Q91ZV8), AGRA3_DANRE (S4X0Q8), AGRA3_HUMAN (Q8IWK6), AGRA3_MOUSE (Q7TT36), AGRB1_HUMAN (O14514), AGRB1_MOUSE (Q3UHD1), AGRB1_RAT (C0HL12), AGRB2_HUMAN (O60241), AGRB2_MOUSE (Q8CGM1), AGRB2_PONAB (Q5R7Y0), AGRB3_HUMAN (O60242), AGRB3_MOUSE (Q80ZF8), AGRD1_BOVIN (A6QLU6), AGRD1_HUMAN (Q6QNK2), AGRD1_MOUSE (Q80T32), AGRD2_HUMAN (Q7Z7M1), AGRE1_HUMAN (Q14246), AGRE1_MOUSE (Q61549), AGRE1_RAT (Q5Y4N8), AGRE2_CANLF (Q2Q421), AGRE2_HUMAN (Q9UHX3), AGRE2_MACMU (Q2Q426), AGRE3_HUMAN (Q9BY15), AGRE4_HUMAN (Q86SQ3), AGRE4_MOUSE (Q91ZE5), AGRE5_BOVIN (Q8SQA4), AGRE5_HUMAN (P48960), AGRE5_MOUSE (Q9Z0M6), AGRF1_HUMAN (Q5T601), AGRF1_MOUSE (Q8VEC3), AGRF2_HUMAN (Q8IZF7), AGRF2_MOUSE (E9Q4J9), AGRF2_RAT (D4A3T6), AGRF3_HUMAN (Q8IZF5), AGRF3_MOUSE (Q58Y75), AGRF4_HUMAN (Q8IZF3), AGRF4_MOUSE (Q9D2L6), AGRF5_HUMAN (Q8IZF2), AGRF5_MOUSE (G5E8Q8), AGRF5_RAT (Q9WVT0), AGRG1_GORGO (Q50DM6), AGRG1_HUMAN (Q9Y653), AGRG1_MACMU (Q50DM8), AGRG1_MOUSE (Q8K209), AGRG1_PANTR (Q50DM7), AGRG1_PONPY (Q50DM5), AGRG1_RAT (Q8K3V3), AGRG2_HUMAN (Q8IZP9), AGRG2_MOUSE (Q8CJ12), AGRG2_RAT (Q8CJ11), AGRG3_HUMAN (Q86Y34), AGRG3_MOUSE (Q8R0T6), AGRG4_HUMAN (Q8IZF6), AGRG4_MOUSE (B7ZCC9), AGRG5_HUMAN (Q8IZF4), AGRG5_MOUSE (Q3V3Z3), AGRG6_DANRE (C6KFA3), AGRG6_HUMAN (Q86SQ4), AGRG6_MOUSE (Q6F3F9), AGRG7_HUMAN (Q96K78), AGRG7_MOUSE (Q8BM96), AGRL1_BOVIN (O97831), AGRL1_HUMAN (O94910), AGRL1_MOUSE (Q80TR1), AGRL1_RAT (O88917), AGRL2_BOVIN (O97817), AGRL2_HUMAN (O95490), AGRL2_MOUSE (Q8JZZ7), AGRL2_RAT (O88923), AGRL3_BOVIN (O97827), AGRL3_HUMAN (Q9HAR2), AGRL3_MOUSE (Q80TS3), AGRL3_RAT (Q9Z173), AGRL4_DANRE (Q7SY09), AGRL4_HUMAN (Q9HBW9), AGRL4_MOUSE (Q923X1), AGRL4_RAT (Q9ESC1), AGRV1_DANRE (Q6JAN0), AGRV1_HUMAN (Q8WXG9), AGRV1_MOUSE (Q8VHN7), CELR1_HUMAN (Q9NYQ6), CELR1_MOUSE (O35161), CELR2_HUMAN (Q9HCU4), CELR2_MOUSE (Q9R0M0), CELR2_RAT (Q9QYP2), CELR3_HUMAN (Q9NYQ7), CELR3_MOUSE (Q91ZI0), CELR3_RAT (O88278), CELR_CAEEL (G5EDK5), LPHN_DROAN (B3MFV7), LPHN_DROER (B3N8M1), LPHN_DROGR (B4J780), LPHN_DROME (A1Z7G7), LPHN_DROMO (B4KMZ1), LPHN_DROPE (B4GD14), LPHN_DROPS (Q292N4), LPHN_DROSE (B4HS00), LPHN_DROVI (B4LNA8), LPHN_DROYA (B4P3A0), LPLT1_CAEEL (G5EDW2), LPLT2_CAEEL (G5ECX0), PK1L1_HUMAN (Q8TDX9), PK1L1_MOUSE (Q8R526), PK1L1_ORYLA (E7FKV8), PK1L2_HUMAN (Q7Z442), PK1L2_MOUSE (Q7TN88), PK1L3_HUMAN (Q7Z443), PK1L3_MOUSE (Q2EG98), PK1L_ACRMI (B8UU59), PKD1_CAEEL (Q09624), PKD1_HUMAN (P98161), PKD1_MOUSE (O08852), STAN_DROME (Q9V5N8), SUREJ_STRPU (Q26627)» more
|
| PDB [Detailed view] |
40 PDB
2BO2; 2BOU; 2BOX; 4DLO; 4DLQ; 5KVM; 6VHH; 7D76; 7D77; 7DO4; 7EPT; 7EQ1; 7QU8; 7SF7; 7SF8; 7WU2; 7WU3; 7WU4; 7WU5; 7WUI; 7WUJ; 7WUQ; 7WXU; 7WXW; 7WY0; 7WY5; 7WY8; 7WYB; 7WZ7; 7X10; 7X2V; 7XKE; 7YDH; 7YDJ; 7YDM; 7YDP; 7YP7; 8IKJ; 8IKL; 8OEK » more |