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PROSITE entry PS50256


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General information about the entry

Entry name [info] PIR_REPEAT_2
Accession [info] PS50256
Entry type [info] MATRIX
Date [info] 01-DEC-2001 CREATED;
10-MAY-2017 DATA UPDATE;
27-MAR-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00718
Associated ProRule [info] PRU00149

Name and characterization of the entry

Description [info] Yeast PIR proteins repeats profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=19;
/DISJOINT: DEFINITION=PROTECT; N1=2; N2=18;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.2710000; R2=0.0188288; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=633.1967163; R2=0.6803279; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=438; H_SCORE=931; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=331; H_SCORE=858; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=-50; E1=-50; MI=-105; MD=-105; IM=-105; DM=-105;
...
                A   B   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y   Z
/I:         B1=0; BI=-105; BD=-105;
/M: SY='A';  M= 15, -5,-16,-10, -6,-19,-11,-16,-15, -1,-15,-11, -4, -6, -6, -3,  9, 11, -6,-26,-16, -6;
/M: SY='A';  M= 14,  1,-16, -5, -3,-21, -8,  2,-17, -6,-18,-11,  4,-12,  0, -8, 13,  7,-11,-28,-13, -2;
/M: SY='A';  M= 30,-15,-15,-22,-14,-17, -5,-22, -2,-14, -8, -6,-14, -6,-15,-21,  2, -3,  6,-22,-18,-15;
/M: SY='V';  M= 14,-23,-16,-30,-23, -7,-23,-27, 22,-20,  6,  6,-20,-20,-20,-23, -6, -3, 27,-24,-10,-23;
/M: SY='S';  M= 12, -3,-11, -4, -3,-14, -2,-12,-18,-11,-26,-18,  6,-11, -3,-12, 33, 16, -8,-35,-17, -3;
/M: SY='Q';  M= -9, -3,-28, -3, 15,-36,-21,  6,-15,  7,-17,  1, -3,-12, 51,  7, -1, -9,-22,-21,-10, 33;
/M: SY='I';  M= -7,-27,-26,-35,-27, -2,-35,-28, 41,-27, 14, 15,-18,-20,-19,-27,-13, -6, 28,-23, -3,-27;
/M: SY='G';  M= -1, -2,-20, -5, -9,-21, 15, -7,-26, -9,-24,-16,  7,-15, -7, -4, 13,  7,-18,-29,-18, -9;
/M: SY='D';  M=-20, 50,-30, 70, 20,-40,-10,  0,-40,  0,-30,-30, 20,-10,  0,-10,  0,-10,-30,-40,-20, 10;
/M: SY='G';  M=  0,-10,-30,-10,-20,-30, 70,-20,-40,-20,-30,-20,  0,-20,-20,-20,  0,-20,-30,-20,-30,-20;
/M: SY='Q';  M=-10,  0,-30,  0, 20,-40,-20, 10,-20, 10,-20,  0,  0,-10, 60, 10,  0,-10,-30,-20,-10, 40;
/M: SY='V';  M= -5,-30,-19,-34,-29,  1,-34,-29, 38,-25, 17, 15,-26,-26,-25,-24,-16, -5, 39,-25, -5,-29;
/M: SY='Q';  M=-10, -2,-29, -2, 18,-37,-21,  8,-18,  8,-16,  1, -2,-11, 55,  8, -2,-10,-28,-20, -9, 36;
/M: SY='A';  M= 38,-15,-11,-23,-15,-15, -8,-22,  1,-13, -5, -5,-14,-14,-14,-21,  5, -1, 10,-22,-17,-15;
/M: SY='T';  M=  4, -2,-12,-10, -9,-12,-17,-20,-11,-10,-12,-11, -2, -4,-10,-11, 18, 41, -2,-30,-12,-10;
/M: SY='T';  M=  3,  0,-14, -9, -7,-14,-16,-17,-11, -3,-14,-10,  2,-11, -7, -6, 14, 29, -3,-28,-12, -7;
/M: SY='S';  M=  8, -2,-18, -6,  3,-22,-13,-11,-17,  6,-18,-10, -1,-10,  5, -1, 10,  9,-11,-26,-14,  4;
/M: SY='T';  M=  1, -8,-16,-13,-10,-13,-16,-20, -9, -2,-12, -8, -7,-15,-10, -6,  7, 20,  2,-21,-11,-10;
/M: SY='T';  M=  4, -6,-16,-11, -8,-11,-15,-14, -8, -7, -8, -7, -3,-11, -8, -9,  7, 14, -3,-25, -8, -9;
/I:         E1=0;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_02 which contains 571'282 sequence entries.


Total number of hits 116 in 23 different sequences
Number of true positive hits 116 in 23 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] window20_shuffled
Author [info] K_Hofmann
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 13
Feature key [info] REPEAT
Feature description [info] PIR1/2/3 repeat
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
23 sequences

ANS1_YEAST  (P38832), CIS3_YEAS6  (B5VL27), CIS3_YEAS7  (A6ZQH4), 
CIS3_YEAST  (P47001), CWP1_YEAST  (P28319), CWP2_YEAST  (P43497), 
HS150_YEAS1 (B3LPW4), HS150_YEAS6 (B5VL26), HS150_YEAS7 (A6ZQH3), 
HS150_YEAST (P32478), PIR1_CANAL  (Q59SF7), PIR1_YEAS1  (B3LQU0), 
PIR1_YEAS7  (A6ZZG0), PIR1_YEAST  (Q03178), PIR3_YEAS1  (B3LQU1), 
PIR3_YEAS7  (A6ZZG1), PIR3_YEAST  (Q03180), PIR5_YEAS1  (B3LPW3), 
PIR5_YEAS6  (B5VL25), PIR5_YEAS7  (A6ZQH2), PIR5_YEAST  (P46999), 
TIR1_YEAST  (P10863), TIR2_YEAST  (P33890)
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