PROSITE documentation PDOC00718Yeast PIR proteins repeats signature and profile
Description
A number of yeast cell wall glycoproteins are characterized by the presence of tandem repeats of a region of 18 to 19 residues [1,2,3]. These proteins are:
- CCW7 (9 repeats).
- CCW11 (1 repeat).
- CWP2 or LPR1.
- PIR1 or CCW6 (8 repeats).
- PIR2 or HSP150 (11 repeats).
- PIR3 or CCW8 (10 repeats).
- TIR1 or SRP1 (1 repeat) (see <PDOC00596>).
- TIR2 or SRP2 (1 repeat) (see <PDOC00596>).
- Hypothetical protein YHR126c (1 repeat).
- Hypothetical protein YJL160c (4 repeats).
The core region of the repeat is highly conserved and is used here as a signature pattern. We also developed a profile that spans the complete repeat.
Last update:December 2001 / Text revised; profile added.
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References
| 1 | Authors | Toh-E A. Yasunaga S. Nisogi H. Tanaka K. Oguchi T. Matsui Y. |
| Source | Yeast 9:481-494(1993). |
| 2 | Authors | Bairoch A. |
| Source | Unpublished observations (1994). |
| 3 | Authors | Mrsa V. Seidl T. Gentzsch M. Tanner W. |
| Title | Specific labelling of cell wall proteins by biotinylation. Identification of four covalently linked O-mannosylated proteins of Saccharomyces cerevisiae. | |
| Source | Yeast 13:1145-1154(1997). | |
| PubMed ID | 9301021 | |
| DOI | 10.1002/(SICI)1097-0061(19970930)13:12<1145::AID-YEA163>3.0.CO;2-Y |
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