We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
PROSITE documentation PDOC00718Yeast PIR proteins repeats signature and profile
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PURL: https://purl.expasy.org/prosite/documentation/PDOC00718
Description
A number of yeast cell wall glycoproteins are characterized by the presence of tandem repeats of a region of 18 to 19 residues [1,2,3]. These proteins are:
- CCW7 (9 repeats).
- CCW11 (1 repeat).
- CWP2 or LPR1.
- PIR1 or CCW6 (8 repeats).
- PIR2 or HSP150 (11 repeats).
- PIR3 or CCW8 (10 repeats).
- TIR1 or SRP1 (1 repeat) (see <PDOC00596>).
- TIR2 or SRP2 (1 repeat) (see <PDOC00596>).
- Hypothetical protein YHR126c (1 repeat).
- Hypothetical protein YJL160c (4 repeats).
The core region of the repeat is highly conserved and is used here as a signature pattern. We also developed a profile that spans the complete repeat.
Last update:December 2001 / Text revised; profile added.
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Technical section
PROSITE methods (with tools and information) covered by this documentation:
References
| 1 | Authors | Toh-E A. Yasunaga S. Nisogi H. Tanaka K. Oguchi T. Matsui Y. |
| Source | Yeast 9:481-494(1993). |
| 2 | Authors | Bairoch A. |
| Source | Unpublished observations (1994). |
| 3 | Authors | Mrsa V. Seidl T. Gentzsch M. Tanner W. |
| Title | Specific labelling of cell wall proteins by biotinylation. Identification of four covalently linked O-mannosylated proteins of Saccharomyces cerevisiae. | |
| Source | Yeast 13:1145-1154(1997). | |
| PubMed ID | 9301021 | |
| DOI | 10.1002/(SICI)1097-0061(19970930)13:12<1145::AID-YEA163>3.0.CO;2-Y |
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