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PROSITE entry PS50507


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50507
Entry name [info] RDRP_SSRNA_POS
Accession [info] PS50507
Entry type [info] MATRIX
Date [info] 01-NOV-2005 CREATED;
01-OCT-2013 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50507
Associated ProRule [info] PRU00539

Name and characterization of the entry

Description [info] RdRp of positive ssRNA viruses catalytic domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=119;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=114;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.6107; R2=0.020803; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=248; N_SCORE=7.75; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=187; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=-1000; E1=-1000; MI=-105; MD=-105; IM=-105; DM=-105; M0=-8;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 494 in 494 different sequences
Number of true positive hits 493 in 493 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 12
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 99.80 %
Recall (true positives / (true positives + false negatives)) 97.62 %

Comments [info]

Taxonomic range [info] Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] S_Spirin, N_Hulo
Feature key [info] DOMAIN
Feature description [info] RdRp catalytic
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
493 sequences

194K_TRVSY  (P05080), NS1AB_ANV1  (Q9JGF2), NS1AB_HASV1 (Q67726), 
» more

UniProtKB/Swiss-Prot
False negative sequences
12 sequences

R1AB_CVHN1  (P0C6X2), R1AB_CVHN2  (P0C6X3), R1AB_CVHN5  (P0C6X4), 
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UniProtKB/Swiss-Prot
False positive sequences
1 sequence

LITD_LATHE  (P0DJE7)

		
PDB
[Detailed view]
339 PDB

1C2P; 1CSJ; 1GX5; 1GX6; 1KHV; 1KHW; 1NB4; 1NB6; 1NB7; 1NHU; 1NHV; 1OS5;
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