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ProRule PRU00539
General rule information
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Accession | PRU00539 |
Dates | 16-MAR-2006 (Created)
30-SEP-2022 (Last updated, Version 11) |
Data class | Domain; |
Predictors |
PROSITE; PS50507; RDRP_SSRNA_POS PROSITE; PS50522; RDRP_PHAGE PROSITE; PS50523; RDRP_DSRNA_REO PROSITE; PS50524; RDRP_DSRNA_BIR PROSITE; PS50525; RDRP_SSRNA_NEG_SEG PROSITE; PS50526; RDRP_SSRNA_NEG_NONSEG |
Name | RdRp |
Function | RNA-directed RNA polymerase. |
Scope(s) |
Viruses |
Example(s) | P24658 (L_CDVO); |
Propagated annotation
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Identifier, protein and gene names
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Protein name | + AltName: Full=RNA-directed RNA polymerase; EC=2.7.7.48; |
Comments
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FUNCTION | RNA-directed RNA polymerase. |
CATALYTIC ACTIVITY | Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA- COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395; EC=2.7.7.48; |
Keywords
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Nucleotide-binding |
Nucleotidyltransferase |
Viral RNA replication |
RNA-directed RNA polymerase |
Transferase |
Gene Ontology
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GO:0000166; Molecular function:nucleotide binding |
GO:0016779; Molecular function:nucleotidyltransferase activity |
GO:0003968; Molecular function:RNA-dependent RNA polymerase activity |
GO:0003723; Molecular function:RNA binding |
GO:0016740; Molecular function:transferase activity |
Features
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From: any | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DOMAIN | from | to | /note="RdRp catalytic #" |
Additional information
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Size range | 90-230 amino acids |
Related rules |
None |
Fusion | None |
Repeats | 1 |
Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Viruses [505] All [ 505 ]
- Retrieve set of proteins with 3D structure for this domain