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ProRule PRU00539


General rule information [?]

Accession PRU00539
Dates 16-MAR-2006 (Created)
30-SEP-2022 (Last updated, Version 11)
Data class Domain;
Predictors PROSITE; PS50507; RDRP_SSRNA_POS
PROSITE; PS50522; RDRP_PHAGE
PROSITE; PS50523; RDRP_DSRNA_REO
PROSITE; PS50524; RDRP_DSRNA_BIR
PROSITE; PS50525; RDRP_SSRNA_NEG_SEG
PROSITE; PS50526; RDRP_SSRNA_NEG_NONSEG
Name RdRp
Function RNA-directed RNA polymerase.
Scope(s) Viruses
Example(s) P24658 (L_CDVO);

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name + AltName: Full=RNA-directed RNA polymerase;
                 EC=2.7.7.48;

Comments [?]

FUNCTIONRNA-directed RNA polymerase.
CATALYTIC ACTIVITY Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA- COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395; EC=2.7.7.48;

Keywords [?]

Nucleotide-binding
Nucleotidyltransferase
Viral RNA replication
RNA-directed RNA polymerase
Transferase

Gene Ontology [?]

GO:0000166; Molecular function:nucleotide binding
GO:0016779; Molecular function:nucleotidyltransferase activity
GO:0003968; Molecular function:RNA-dependent RNA polymerase activity
GO:0003723; Molecular function:RNA binding
GO:0016740; Molecular function:transferase activity

Features [?]

From: any
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="RdRp catalytic #"

Additional information [?]

Size range 90-230 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

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UniProtKB rule member sequences [?]