Accession	PRU00539
Dates	16-MAR-2006 (Created) 27-OCT-2018 (Last updated, Version 8)

Data class

Domain

Predictors

PROSITE; PS50507; RDRP_SSRNA_POS

Predictors

PROSITE; PS50522; RDRP_PHAGE

Predictors

PROSITE; PS50523; RDRP_DSRNA_REO

Predictors

PROSITE; PS50524; RDRP_DSRNA_BIR

Predictors

PROSITE; PS50525; RDRP_SSRNA_NEG_SEG

Predictors

PROSITE; PS50526; RDRP_SSRNA_NEG_NONSEG

Name

RdRp

Function

RNA-directed RNA polymerase.

+ AltName: Full=RNA-directed RNA polymerase; EC=2.7.7.48;

Function	RNA-directed RNA polymerase.
Catalytic activity	Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:11128, Rhea:RHEA- COMP:11129, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:83400; EC=2.7.7.48;.

GO:0000166; Molecular function: nucleotide binding.
GO:0016779; Molecular function: nucleotidyltransferase activity.
GO:0003968; Molecular function: RNA-directed 5'-3' RNA polymerase activity.
GO:0003723; Molecular function: RNA binding.
GO:0016740; Molecular function: transferase activity.

Nucleotide-binding
Nucleotidyltransferase
Viral RNA replication
RNA-directed RNA polymerase
Transferase

From: any

Key

From

To

Description

Tag

Condition

FTGroup

DOMAIN

from

to

RdRp catalytic #

Size range	90-230 amino acids
Related rules	None
Repeats	1
Topology	Undefined
Example	P24658 (L_CDVO)
Scope	Viruses

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

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• UniProtKB/Swiss-Prot sets
  

  Viruses

  [490]

  
  
• Retrieve set of proteins with 3D structure for this domain