PROSITE entry PS50877
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General information about the entry
| Entry name [info] | GOLOCO |
| Accession [info] | PS50877 |
| Entry type [info] | MATRIX |
| Date [info] |
01-APR-2003 CREATED;
10-MAY-2017 DATA UPDATE; 03-MAY-2023 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC50877 |
| Associated ProRule [info] | PRU00097 |
Name and characterization of the entry
| Description [info] | GoLoco/GPR motif profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=23; /DISJOINT: DEFINITION=PROTECT; N1=3; N2=21; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.5159345; R2=0.0172079; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=904.4058838; R2=0.6058823; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=447; H_SCORE=1175; N_SCORE=8.2; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=348; H_SCORE=1115; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-7; D=-20; I=-20; B1=-100; E1=-100; MI=-105; MD=-105; IM=-105; DM=-105; ... A B C D E F G H I K L M N P Q R S T V W Y Z /I: B1=0; BI=-105; BD=-105; /M: SY='D'; M=-10, 5,-27, 7, 3,-24, -6, -7,-18, -4,-18,-10, 4, -5, 1, -4, -1, -5,-18,-29,-17, 1; /M: SY='E'; M=-12, 15,-27, 24, 26,-28,-19, -6,-20, 0,-17,-16, 2, -9, 7, -7, -1, -5,-17,-32,-16, 16; /M: SY='D'; M=-13, 26,-29, 37, 28,-34, -6, 0,-34, 2,-26,-23, 13, -8, 10, -5, 1,-10,-30,-33,-20, 19; /M: SY='F'; M=-11,-28,-20,-32,-24, 27,-22,-19, 11,-27, 26, 14,-24,-28,-25,-19,-22,-10, 8,-12, 6,-23; /M: SY='L'; M=-11,-25,-19,-30,-22, 22,-28,-14, 12,-22, 24, 17,-23,-27,-20,-17,-19, -4, 9,-11, 12,-21; /M: SY='D'; M= -5, 21,-24, 27, 27,-29,-10, -2,-28, 1,-25,-22, 14, -8, 7, -6, 8, -3,-24,-35,-20, 17; /M: SY='M'; M= -8,-23,-21,-28,-20, 1,-20,-14, 16,-21, 27, 28,-21,-23,-13,-17,-19, -5, 8,-21, -3,-17; /M: SY='L'; M= -9,-30,-23,-34,-25, 5,-34,-25, 32,-29, 35, 19,-26,-26,-21,-24,-25, -9, 21,-21, -1,-25; /M: SY='M'; M= -7, -8,-22,-14, -5, -2,-20, -9, 2, -8, 4, 10, -4,-19, -7, -9,-11, -7, -1,-23, -6, -6; /M: SY='R'; M=-10, -2,-25, -4, 2,-22,-14, -4,-27, 23,-25,-13, 6,-16, 7, 39, 3, -2,-18,-26,-13, 2; /M: SY='M'; M= -3,-18, -9,-23,-19, -4,-22, -3, 8,-14, 3, 18,-17,-23,-11,-14, -8, -2, 13,-24, 0,-16; /I: I=-6; MD=-29; /M: SY='Q'; M= -9, 0,-27, 0, 18,-37,-18, 9,-18, 9,-18, 0, 0, -9, 55, 9, 0, -9,-27,-18, -9, 37; D=-6; /I: I=-6; MI=0; MD=-29; IM=0; DM=-29; /M: SY='S'; M= 8, -7, -5, -9,-10,-21, 13,-16,-22,-16,-22,-16, 0,-17,-10,-16, 18, 3,-13,-33,-22,-10; /M: SY='S'; M= 4, -2,-19, -3, -3,-24, 10, -9,-25, -5,-27,-16, 8,-14, 2, -1, 18, 3,-18,-30,-20, -1; /M: SY='R'; M=-17,-10,-30,-10, -3,-22, -5, -3,-32, 22,-22,-12, 0,-20, 5, 55, -8,-12,-22,-20,-13, -3; /M: SY='M'; M= 0,-22,-19,-29,-19, 0,-21,-12, 17,-18, 25, 33,-22,-22, -9,-16,-18, -8, 10,-20, -3,-15; /M: SY='D'; M=-16, 25,-30, 38, 34,-33,-16, 16,-34, 3,-24,-21, 10, -7, 10, -4, -2,-12,-30,-34,-13, 21; /M: SY='D'; M=-12, 37,-28, 53, 25,-36,-11, -2,-35, 1,-26,-26, 14, -8, 3, -9, 1, -9,-27,-36,-20, 14; /M: SY='Q'; M=-10, 0,-30, 0, 20,-40,-20, 10,-20, 10,-20, 0, 0,-10, 60, 10, 0,-10,-30,-20,-10, 40; /M: SY='R'; M=-20,-10,-30,-10, 0,-20,-20, 0,-30, 30,-20,-10, 0,-20, 10, 70,-10,-10,-20,-20,-10, 0; /M: SY='C'; M= 10,-11, 12,-16,-16,-20, 6,-21,-20,-17,-19,-15, -6,-20,-16,-19, 9, 2, -8,-32,-23,-16; /M: SY='E'; M= -6, -4,-22, -2, 13,-17,-18, -1,-16, -5,-10,-10, -4, -5, 2, -4, 3, 3,-15,-30,-12, 6; /M: SY='L'; M=-11,-24,-25,-24,-13, 6,-27,-19, 8,-21, 16, 8,-23, -1,-17,-19,-20, -9, 1,-20, -5,-16; /I: E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
| Total number of hits | 41 in 21 different sequences |
| Number of true positive hits | 41 in 21 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | N_Hulo |
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 4 |
| Feature key [info] | DOMAIN |
| Feature description [info] | GoLoco |
| Version [info] | 5 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
21 sequences
GPR1_CAEEL (Q95QJ7 ), GPR2_CAEEL (Q03569 ), GPSM1_HUMAN (Q86YR5 ), GPSM1_MOUSE (Q6IR34 ), GPSM1_RAT (Q9R080 ), GPSM2_HUMAN (P81274 ), GPSM2_MOUSE (Q8VDU0 ), GPSM3_HUMAN (Q9Y4H4 ), GPSM3_MOUSE (Q3U1Z5 ), GPSM3_RAT (Q6MG88 ), PCP2_HUMAN (Q8IVA1 ), PCP2_MOUSE (P12660 ), RGS12_HUMAN (O14924 ), RGS12_MOUSE (Q8CGE9 ), RGS12_RAT (O08774 ), RGS14_HUMAN (O43566 ), RGS14_MOUSE (P97492 ), RGS14_RAT (O08773 ), RGS_DROME (Q9VCX1 ), RPGP1_HUMAN (P47736 ), RPGP1_MOUSE (A2ALS5 )» more
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| PDB [Detailed view] |
10 PDB
1KJY; 2OM2; 2XNS; 3ONW; 3QI2; 4G5O; 4G5Q; 4G5R; 4G5S; 4JHR |