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PROSITE entry PS51008


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General information about the entry

Entry name [info] MULTIHEME_CYTC
Accession [info] PS51008
Entry type [info] MATRIX
Date [info] 01-AUG-2004 CREATED;
01-AUG-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00169

Name and characterization of the entry

Description [info] Multiheme cytochrome c family profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=15; TOPOLOGY=CIRCULAR;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=15;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.8475713; R2=0.0151062; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=375; N_SCORE=7.5; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=275; N_SCORE=6.0; MODE=1; TEXT='RR';
/DEFAULT: M0=-9; D=-20; I=-20; B0=-200; B1=-200; E0=-200; E1=-200; MI=-105; MD=-105; IM=-105; DM=-105;
...
                A    B    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y    Z
/I:         B0=0; B1=0; E0=0; E1=0; BI=-105; BD=-105; IE=-105; DE=-105;
/M: SY='N';  M=  -3,  -2, -70,  -4,  -1, -19, -18, -10, -15,  -2, -14,  -9,   1, -11,  -2,  -4,  -1,  -4, -12, -24, -13,  -2;
/I:         I0=0; I=-1;
/M: SY='N';  M=  -8,   0, -70,  -1,  -2, -16, -12, -80, -16,  -1, -15, -10,   0,  -7,  -2,  -1,  -1,   0, -14, -23, -10,  -3;
/M: SY='E';  M=  -4,   2, -90,   3,   5, -24,  -5, -30, -20,  -3, -20, -13,   2,  -3,   2,  -4,   2,  -5, -18, -28, -17,   2;
/M: SY='A';  M=   1,  -8, -70,  -8,  -1, -19, -17, -30,  -8,   1,  -9,  -5,  -5, -10,  -3,  -3,  -4,  -4,  -3, -25, -13,  -3;
/M: SY='S';  M=  -2,   1, -70,  -2,  -4,  -5,  -3, -30, -17,  -8, -16, -12,   3, -15,  -6,   0,   6,   6, -12, -24, -12,  -5;
/M: SY='C';  M=   *,   *, 120,   *,   *,   *,   *,   *,   *,   *,   *,   *,   *,   *,   *,   *,   *,   *,   *,   *,   *,   *;
/M: SY='A';  M=   6, -14, -80, -19, -14, -10, -14, -55,   1, -11,  -3,  -1, -11, -48, -10,  -9,  -1,   1,   5, -19,  -7, -13;
/M: SY='S';  M=   2,   8, -80,   7,   1, -21,   0, -58, -20,  -6, -20, -15,   7, -42,  -1,  -9,  11,   7, -15, -29, -14,   0;
/M: SY='C';  M=   *,   *, 120,   *,   *,   *,   *,   *,   *,   *,   *,   *,   *,   *,   *,   *,   *,   *,   *,   *,   *,   *;
/M: SY='H';  M=   *,   *,   *,   *,   *,   *,   *, 120,   *,   *,   *,   *,   *,   *,   *,   *,   *,   *,   *,   *,   *,   *;
/M: SY='N';  M=  -1,  -1, -70,  -4,  -4, -18, -25, -10, -13,  -3, -14,  -7,   3, -16, -10,  -4,   3,   0,  -4, -28, -14,  -3;
/M: SY='E';  M=  -5,  -1, -70,   0,   2, -19,  -9, -30, -16,  -4, -16, -10,  -2,  -1,  -2,  -7,  -2,  -6, -15, -25, -14,  -1;
/M: SY='E';  M=  -6,  -2, -70,  -2,   3, -19, -25, -30, -15,  -1, -15,  -9,  -2,  -5,   2,  -4,  -3,  -5, -15, -23,  -8,   1;
/M: SY='P';  M=  -3,   1, -70,   2,   1, -17,  -8, -30, -20,  -5, -20, -15,   0,   3,  -6,  -9,   2,  -2, -16, -26, -15,  -3;
/I:         I0=0; I=-1;
/M: SY='E';  M=  -1,   0,-110,   1,   6, -20, -10, -30, -19,  -1, -18, -11,  -1,  -4,   4,  -5,   0,  -5, -17, -24, -12,   4;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 166 in 158 different sequences
Number of true positive hits 166 in 158 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 5
Number of 'partial' sequences 3
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 97.08 %

Comments [info]

Taxonomic range [info] Archaea, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 3
Matrix type [info] protein_domain
Scaling database [info] window20
Author [info] N_Hulo
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
158 sequences

C554_CHLAA  (P33325), C554_NITEU  (Q57142), CGR1_EGGLE  (C8WLM0), 
CYC32_DESNO (P38554), CYC32_NITV2 (Q727P6), CYC3A_DESAF (P94690), 
CYC3B_DESAF (P94691), CYC3_DESDE  (P00134), CYC3_MARSL  (P00135), 
CYC3_MEGG1  (P00133), CYC3_NITV2  (P00131), CYC3_SHEFN  (O33731), 
CYC9_DESDA  (Q9RN68), CYCB_GEOSK  (D7ALQ0), CYCB_GEOSL  (Q749K5), 
CYCC_GEOSK  (D7ALP6), CYCC_GEOSL  (Q749L1), CYCR_ALLVD  (O82947), 
CYCR_BLAVI  (P07173), CYCR_ROSDO  (P26278), CYCR_RUBGI  (P51758), 
CYCR_THETI  (D2Z0P5), CYCX_NITEU  (Q50926), CYMA_SHEON  (Q8E8S0), 
ENCAP_KUEST (Q1Q6L7), FCCA_SHEFN  (Q07WU7), FCCA_SHEFR  (P0C278), 
FCCA_SHEON  (P83223), HAO_NITEU   (Q50925), HDH_KUEST   (Q1PW30), 
HMEE_ARCFU  (O29747), HMWC_NITV2  (P24092), IFCA_SHEFN  (Q9Z4P0), 
IMCH_GEOSL  (Q747K6), MAME_MAGGM  (V6F2B6), MAME_PARM1  (Q2W8Q8), 
MAMX_MAGGM  (V6F2C2), MAMX_PARM1  (Q2W8K4), MAUG_METME  (Q50233), 
MCCA_SHEON  (Q8EJI6), MCCA_WOLSU  (Q7MSJ8), MTRA_SHEB8  (P0DSN3), 
MTRC_SHEB8  (P0DSN4), NAPB_AZOBR  (Q8VU46), NAPB_BRAJP  (Q8KY07), 
NAPB_CERS4  (Q53177), NAPB_CERSP  (O88160), NAPB_CUPNH  (P39186), 
NAPB_ECOLI  (P0ABL3), NAPB_HAEIN  (P44654), NAPB_NEOGA  (Q9Z3W3), 
NAPB_PARPN  (Q56351), NAPB_SHIFL  (P0ABL4), NAPB_WOLSU  (Q7M963), 
NAPC_CERS4  (Q53178), NAPC_ECO57  (P0ABL7), NAPC_ECOL6  (P0ABL6), 
NAPC_ECOLI  (P0ABL5), NAPC_HAEIN  (P44655), NAPC_PARPN  (Q56352), 
NIRT_STUST  (P24038), NIR_THIND   (L0DSL2), NRFA_ALIB4  (A8ERP8), 
NRFA_ALIF1  (Q5E4J7), NRFA_ALIFM  (B5FEY0), NRFA_ALISL  (B6EH98), 
NRFA_BACFN  (Q5LI95), NRFA_BACFR  (Q64ZA7), NRFA_BACTN  (Q8A7V7), 
NRFA_CITK8  (A8AN26), NRFA_DESPS  (Q6ARF1), NRFA_ECO24  (A7ZUU5), 
NRFA_ECO27  (B7UPN8), NRFA_ECO45  (B7MJT8), NRFA_ECO55  (B7LB19), 
NRFA_ECO57  (P0ABL0), NRFA_ECO5E  (B5Z1D1), NRFA_ECO7I  (B7NSN2), 
NRFA_ECO81  (B7N2T7), NRFA_ECO8A  (B7M7Y3), NRFA_ECOBW  (C5A163), 
NRFA_ECODH  (B1XCV6), NRFA_ECOHS  (A8A7H1), NRFA_ECOK1  (A1AIR1), 
NRFA_ECOL5  (Q0T9X8), NRFA_ECOL6  (Q8CVI1), NRFA_ECOLC  (B1IUI1), 
NRFA_ECOLI  (P0ABK9), NRFA_ECOLU  (B7NG13), NRFA_ECOSE  (B6I5T8), 
NRFA_ECOSM  (B1LPN5), NRFA_ECOUT  (Q1R3J6), NRFA_EDWI9  (C5BES4), 
NRFA_HAEDU  (Q7VNX8), NRFA_HAEI8  (Q4QLL8), NRFA_HAEIN  (P45017), 
NRFA_MANHA  (Q06PW6), NRFA_MANSM  (Q65RI4), NRFA_MARSD  (C6BYZ2), 
NRFA_NITV2  (Q72EF3), NRFA_PARD8  (A6L890), NRFA_PASMU  (Q9CPL4), 
NRFA_PECAS  (Q6D613), NRFA_PECCP  (C6DK80), NRFA_PHOPR  (Q6LSQ7), 
NRFA_PORGI  (Q7MTW1), NRFA_SALA4  (B5F2F2), NRFA_SALAR  (A9MGK5), 
NRFA_SALCH  (Q57GV0), NRFA_SALDC  (B5FRF3), NRFA_SALEP  (B5QZA1), 
NRFA_SALG2  (B5R941), NRFA_SALHS  (B4TEB5), NRFA_SALNS  (B4T1X2), 
NRFA_SALPA  (Q5PJ02), NRFA_SALPB  (A9N1R7), NRFA_SALPC  (C0Q554), 
NRFA_SALPK  (B5BJZ8), NRFA_SALSV  (B4TRK5), NRFA_SALTI  (Q8Z1Q9), 
NRFA_SALTY  (Q8ZKF5), NRFA_SHEAM  (A1S3A0), NRFA_SHEFN  (Q087T3), 
NRFA_SHEON  (Q8EAC7), NRFA_SHEPC  (A4Y382), NRFA_SHESA  (A0KSX7), 
NRFA_SHESH  (A8FRR9), NRFA_SHESM  (Q0HMH8), NRFA_SHESR  (Q0HRB0), 
NRFA_SHESW  (A1RNQ3), NRFA_SHEWM  (B1KFU9), NRFA_SHIB3  (B2TXA4), 
NRFA_SHIBS  (Q31TS5), NRFA_SHIFL  (Q83P93), NRFA_SHISS  (Q3YUR5), 
NRFA_SULDE  (Q9Z4P4), NRFA_VIBPA  (Q87ND9), NRFA_VIBVU  (Q8D8E5), 
NRFA_VIBVY  (Q7MM23), NRFA_WOLSU  (Q9S1E5), NRFB_ECOL6  (P0ABL2), 
NRFB_ECOLI  (P0ABL1), NRFB_HAEIN  (P45016), NRFH_NITV2  (Q72EF4), 
NRFH_WOLSU  (Q9S1E6), NRHAO_KUEST (P0DV45), PCRC_DECAR  (Q47CW8), 
QRCA_NITV2  (P0DOV3), SOXA_PARPN  (O33434), TORC_ECO57  (P58359), 
TORC_ECOLI  (P33226), TORY_ECO57  (P58361), TORY_ECOLI  (P52005), 
TORY_HAEIN  (P44799), Y1237_ARCFU (O29031), YEBS_ECO57  (P0AD04), 
YEBS_ECOLI  (P0AD03), YFCC_ALLVD  (Q06536)
» more

UniProtKB/Swiss-Prot
False negative sequences
5 sequences

CYC31_DESNO (P00136), CYC3_DESAC  (P00137), CYC3_NITV9  (P00132), 
CYCX_DESDA  (P81040), NAPB_SHEON  (Q8EIJ4)
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UniProtKB/Swiss-Prot
'Partial' sequences
3 sequences

CYC31_NITVL (P81149), CYC32_NITVL (P81151), CYC35_DESAC (P81079)

		
PDB
[Detailed view]
172 PDB

19HC; 1A2I; 1AQE; 1BVB; 1CZJ; 1D4C; 1D4D; 1D4E; 1DXR; 1E39; 1EHJ; 1F22; 1FGJ; 1FS7; 1FS8; 1FS9; 1FT5; 1FT6; 1GU6; 1GWS; 1GX7; 1H21; 1H29; 1HH5; 1IT1; 1J0O; 1J0P; 1JNI; 1JRX; 1JRY; 1JRZ; 1KSS; 1KSU; 1KWJ; 1L3O; 1LJ1; 1LM2; 1M64; 1MDV; 1NEW; 1OFW; 1OFY; 1OGY; 1P2E; 1P2H; 1PRC; 1Q9I; 1QDB; 1QJD; 1QN0; 1QN1; 1QO8; 1R2C; 1VRN; 1WAD; 1WR5; 1Y0P; 2B7R; 2B7S; 2BPN; 2BQ4; 2C1D; 2CDV; 2CTH; 2CVC; 2CY3; 2CYM; 2E80; 2E81; 2EWI; 2EWK; 2EWU; 2FFN; 2I5N; 2J7A; 2JBL; 2K3V; 2OT4; 2OZY; 2P0B; 2PRC; 2RDZ; 2RF7; 2VR0; 2WJM; 2WJN; 2X5U; 2X5V; 2YXC; 2YYW; 2YYX; 2Z47; 2ZO5; 3BNF; 3BNG; 3BNH; 3BNJ; 3CAO; 3CAR; 3D1I; 3D38; 3F29; 3FO3; 3G7F; 3GM6; 3L1T; 3LG1; 3LGQ; 3ML1; 3MMO; 3O5A; 3OWM; 3PRC; 3RKH; 3S7W; 3SCE; 3T6D; 3T6E; 3TOR; 3UBR; 3UU9; 3WMM; 4AC5; 4CAS; 4FAS; 4L38; 4L3X; 4L3Y; 4L3Z; 4N4N; 4N4O; 4Q0T; 4Q17; 4Q1O; 4Q4U; 4Q5B; 4Q5C; 4RKM; 4RKN; 4V8K; 4WJY; 5B5M; 5B5N; 5M7J; 5M7K; 5M7L; 5NJ4; 5O4C; 5O64; 5PRC; 5Y5S; 6ET5; 6HIF; 6M0P; 6M0Q; 6P73; 6PRC; 6QYC; 6R2Q; 6ZHW; 6ZI4; 6ZI5; 6ZI6; 6ZI9; 6ZIA; 6ZID; 7C52; 7PRC; 7Q7P; 7Q7Q; 8WDU; 8WDV
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