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Entry: PS51039

General information about the entry

Entry name [info] ZF_AN1
Accession [info] PS51039
Entry type [info] MATRIX
Date [info] 01-NOV-2004 CREATED;
02-JUN-2021 DATA UPDATE;
02-JUN-2021 INFO UPDATE.
PROSITE Doc. [info] PDOC51039
Associated ProRule [info] PRU00449

Name and characterization of the entry

Description [info] Zinc finger AN1-type profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=50;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=45;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3496473; R2=0.0103997; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=1313; N_SCORE=16.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=400; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-32; D=-120; I=-120; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='P';  M=  24, -74,  -6, -26, -72, -67, -64, -37,  48, -13, -58, -59,  59,  25, -10, -41,   8,  13, -78, -68;
/M: SY='K';  M= -21, -75,  47, -23, -74, -40,  34,  -6,  60, -53, -62, -26,  12,  14, -29, -23,  12,   3, -82, -64;
/M: SY='K';  M=  12, -71, -37, -48,  22, -28, -65,   4,  46,  14, -53, -12,  -5, -57,   0,  12,  19, -16, -72, -58;
/M: SY='K';  M= -24, -74,  12, -53, -77,  42, -62, -73,  55, -75, -22, -28,  20,  -6,   7,  11,  22, -26, -78, -69;
/M: SY='N';  M= -14, -72, -50, -31, -18, -36,  26, -70,  40, -72, -63,  80,   1,  -5,  13,   3, -37, -20, -75,  21;
/M: SY='H';  M= -31, -78, -59, -51, -74, -42,  87, -79,  35, -73, -61, -50, -22, -12,  80, -29,  17, -74, -81, -56;
/M: SY='C';  M= -61, 154, -81, -81, -71, -77, -81, -78, -77, -69, -69, -67, -92, -85, -83, -64, -61, -66,-101, -82;
/M: SY='S';  M=  21,   5, -26, -16,  27, -25, -28, -66, -20, -21, -62,  -6,  34,   6, -63,  61, -19, -48, -72,  -7;
/I:         I=-31; MD=-65;
/M: SY='F';  M= -76, -24, -41,   0,  47, -94,   0, -19, -16, -17,   4, -82, -90, -77,  -3, -80, -73,  39, -80, -16; D=-31;
/I:         I=-31; MD=-65;
/M: SY='P';  M= -25,-102,  -1,   6,-105, -57, -85, -99,  23,-102, -93, -78,  54, -33, -76, -14, -19, -96,-103, -96; D=-31;
/I:         I=-31; MI=-65; MD=-65; IM=-65; DM=-65;
/M: SY='T';  M=   5, -79,  28, -61, -82,  18,   2, -80,   4, -81, -74, -56, -74, -17,  23,  14,  42, -53, -88, -28; D=-31;
/I:         I=-31; DM=-65;
/M: SY='C';  M= -61, 154, -81, -81, -71, -77, -81, -78, -77, -69, -69, -67, -92, -85, -83, -64, -61, -66,-101, -82;
/M: SY='R';  M= -34, -76, -56, -50, -77,  -1, -55, -78,  51, -76, -65,  30, -13,  21,  73,   3,  13, -73, -77, -66;
/M: SY='K';  M= -18, -77, -23,  29, -76, -70, -57, -47,  64, -32, -61, -53, -65,  59,  39, -21,  -3, -15, -76, -65;
/M: SY='K';  M= -29, -74, -65, -56, -62, -43, -61,  11,  57,  23,   5, -58, -71, -51,  52,  12,  -5, -31, -73, -15;
/M: SY='D';  M= -28, -71,  58,  40, -63, -75, -66, -43, -61,  14, -53, -58, -69, -59, -66, -58,  24,  57, -86, -65;
/M: SY='F';  M= -57, -71, -68, -22,  65,  58, -66, -60, -67,  -9,  39, -58, -71, -67, -71,  -2,  43, -60, -64, -49;
/M: SY='L';  M= -65, -69, -80, -74,  32, -83, -69,   3, -28,  70,  24, -76, -79, -69, -23, -70,   8,  12, -69, -50;
/M: SY='P';  M=   4, -72, -66, -22, -17, -68, -65, -54,   0,  21,  37, -62,  65,   5, -63,  11,  41, -21, -76, -63;
/I:         I=-29; MD=-61;
/M: SY='G';  M= -36, -96, -80, -90,-101,  62, -85, -38, -85,-101, -91,  31, -91,  -9, -91, -47, -47, -96,-100, -96; D=-29;
/I:         I=-29; MI=0; MD=-61; IM=0; DM=-61;
/M: SY='F';  M= -66, -72, -80, -75,  92,   3, -68,  21, -72,   8,  -1, -71, -79,  20, -72, -31, -63,   9, -54, -15;
/M: SY='K';  M= -22, -73,   6,  20,  12, -35,  15,  -3,  43, -64, -33,  18, -10, -34,  11,  -9,  31,  -2, -77, -60;
/M: SY='C';  M= -61, 154, -81, -81, -71, -77, -81, -78, -77, -69, -69, -67, -92, -85, -83, -64, -61, -66,-101, -82;
/I:         I=-36; MD=-77;
/M: SY='D';  M= -26, -97,  58, -42, -97, -85, -76, -91,  -1, -47,  20, -16,  16,  -3, -12, -39, -77, -90,-105, -87; D=-36;
/I:         I=-36; MI=-77; IM=-77; DM=-77;
/M: SY='R';  M=  -7, -78,  15, -53,   0,   7,  43, -74,   1, -29, -61, -10, -73,   8,  80, -58, -63, -71, -71,  21;
/M: SY='C';  M= -61, 154, -81, -81, -71, -77, -81, -78, -77, -69, -69, -67, -92, -85, -83, -64, -61, -66,-101, -82;
/M: SY='G';  M= -52, -73, -32, -11, -78,  70,  19, -80,  28, -43, -69,  28, -67, -17, -58,  34, -25, -76, -78, -69;
/M: SY='G';  M=  -9, -74, -57,  -6, -39,  45,  41, -36,  11, -30, -61,  33, -69,  30,  14,   6, -34, -20, -75,  -2;
/M: SY='N';  M= -60, -71,  24, -27, -64, -69,   4,   0,  -9,  -3,  28,  59, -71, -18,  21, -26,  25,  30, -85, -62;
/M: SY='F';  M= -74, -73, -81, -79, 110, -81,  33, -51, -75, -44, -50, -73, -84, -79, -71, -71, -67, -29, -40,  63;
/M: SY='C';  M= -62, 152, -81, -81, -30, -77, -79, -77, -77, -68, -68, -67, -92, -84, -83, -64, -61, -66, -94, -14;
/M: SY='L';  M=  21, -70, -73, -70, -57,  43, -68,  19, -20,  48,  28, -64, -41, -64, -70,   8, -59, -48, -74, -62;
/M: SY='K';  M=  15, -72,  23,  30, -74, -45, -58, -68,  48, -21, -11, -18, -65,  17,   3,  30,   5, -31, -79, -66;
/M: SY='H';  M= -69, -81, -53, -53, -68, -71, 149, -86, -58, -68, -54, -43, -70, -47, -52, -59, -68, -86,-103, -37;
/M: SY='R';  M= -30, -81, -64, -53, -12, -75,  38, -76,   0, -71, -62, -57,  -8, -43, 105, -61, -64, -29, -76, -58;
/M: SY='Y';  M= -28,   9, -69, -35,  48, -37,  67, -55, -67,  29, -48, -63, -50, -62, -66,  15, -19, -58, -54,  76;
/M: SY='P';  M=  11, -78, -64,  -6, -60,  -6, -58, -66, -17, -31,  26, -63,  82,   4, -37,  15, -43, -66, -64,  58;
/M: SY='E';  M=  -3, -76,  39,  69, -17, -24, -59, -69, -13,  -9,  -1, -55,  14, -47,  -2,  -6,   5, -50, -79, -66;
/M: SY='D';  M= -18, -76,  75,   3, -77, -39, -20,   3,  14, -71, -66,  23, -67,  37,  -6,   7, -11, -21, -86, -66;
/M: SY='H';  M= -27, -80, -54, -54, -65, -70, 146, -84, -58, -68, -54, -44, -70, -48, -53, -58, -67, -83, -96,   3;
/M: SY='D';  M=   0, -74,  49,  16, -79,  32,  26, -78,  36, -77, -69,  18, -66, -23, -10,  21, -24, -40, -83, -67;
/M: SY='C';  M= -27, 151, -81, -80, -70, -76, -80, -75, -76, -31, -66, -68, -91, -83, -82, -63, -61, -64, -99, -80;
/M: SY='P';  M=  -1, -74, -59, -10, -76,  23, -63, -71,  -5, -75, -67,   5,  61,  11,  -7,  38,  29, -31,  36, -68;
/M: SY='F';  M= -16, -75, -62,  16,  62,  37,  -3, -66,  18, -29, -60,  -5, -14, -59, -28,  -7, -29, -66,  17,  35;
/M: SY='D';  M=  14, -76,  65, -12, -73,  -3, -60, -32,  18,   5, -62,  -8,  23, -54,  27, -34, -58, -29, -82, -67;
/M: SY='Y';  M=   3, -74, -19,  16,  44, -10,  10, -14, -30, -15, -55,  -1, -15, -59,  -8, -12,  -8, -26, -56,  71;
/M: SY='K';  M= -12, -76, -25, -24, -72, -69,  32,   2,  62, -65,   8, -10, -68,  44,  40,   7, -56,  -3, -77, -61;
/M: SY='P';  M=  19,   5, -62, -14, -73,  27,  -8,   2,  22, -23, -61, -20,  43,  12, -11,  19,  -9, -41, -77, -68;
/M: SY='A';  M=  38, -72,  34,  18, -75, -36,  37, -36,  12, -69, -22,   1,   6, -51,  21,  -9,  13, -11, -83, -65;
/M: SY='A';  M=  43, -70, -41,   8, -27,  38, -66,  -7, -23, -35, -61, -18,  -1, -57,   7,  27, -55,   1, -76, -67;
/I:         E1=0; IE=-255; DE=-255;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2021_03 which contains 565'254 sequence entries.


Total number of hits 80 in 64 different sequences
Number of true positive hits 80 in 64 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 2
Feature key [info] ZN_FING
Feature description [info] AN1-type
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
64 sequences

CUZ1_YEAST  (P53899    ), SAP10_ARATH (Q9STJ9    ), SAP10_ORYSJ (Q69LE0    ), 
SAP11_ARATH (Q8VZ42    ), SAP11_ORYSJ (Q84PD8    ), SAP12_ARATH (Q67YE6    ), 
SAP12_ORYSJ (Q6Z541    ), SAP13_ARATH (Q9SCM4    ), SAP13_ORYSJ (Q5JLA7    ), 
SAP14_ORYSJ (Q852K8    ), SAP15_ORYSJ (Q0DJC7    ), SAP16_ORYSJ (Q0D5B9    ), 
SAP17_ORYSJ (Q6H595    ), SAP1_ARATH  (Q6NNI8    ), SAP1_ORYSI  (A2Z2J6    ), 
SAP1_ORYSJ  (A3C039    ), SAP2_ARATH  (Q8H0X0    ), SAP2_ORYSJ  (Q942F8    ), 
SAP3_ARATH  (Q9ZNU9    ), SAP3_ORYSJ  (Q5JN07    ), SAP4_ARATH  (Q9SJM6    ), 
SAP4_ORYSJ  (Q6H7P8    ), SAP5_ARATH  (Q9LHJ8    ), SAP5_ORYSJ  (Q6H754    ), 
SAP6_ARATH  (Q94B40    ), SAP6_ORYSJ  (Q852K5    ), SAP7_ARATH  (Q9SZ69    ), 
SAP7_ORYSJ  (Q852K6    ), SAP8_ARATH  (Q3EA33    ), SAP8_ORYSI  (A2YEZ6    ), 
SAP8_ORYSJ  (A3BDI8    ), SAP9_ARATH  (O49663    ), SAP9_ORYSJ  (Q7Y1W9    ), 
SMBP2_HUMAN (P38935    ), SMBP2_MESAU (Q60560    ), SMBP2_MOUSE (P40694    ), 
SMBP2_RAT   (Q9EQN5    ), TMC1_YEAST  (Q08422    ), Y8260_DICDI (Q55GW8    ), 
YHM5_SCHPO  (O94338    ), ZFAN1_HUMAN (Q8TCF1    ), ZFAN1_MOUSE (Q8BFR6    ), 
ZFAN3_HUMAN (Q9H8U3    ), ZFAN3_MOUSE (Q497H0    ), ZFAN3_RAT   (Q5U2M7    ), 
ZFAN3_XENLA (Q66J85    ), ZFAN4_HUMAN (Q86XD8    ), ZFAN4_MOUSE (D3Z3C6    ), 
ZFAN5_HUMAN (O76080    ), ZFAN5_MOUSE (O88878    ), ZFAN5_RAT   (B5DF11    ), 
ZFAN6_BOVIN (Q3SZY7    ), ZFAN6_HUMAN (Q6FIF0    ), ZFAN6_MOUSE (Q9DCH6    ), 
ZFAN6_PONAB (Q5R7S6    ), ZFAN6_RAT   (Q6DGF4    ), ZFAND_DICDI (Q55BU1    ), 
ZFN2A_HUMAN (Q8N6M9    ), ZFN2A_MOUSE (Q9JII7    ), ZFN2A_PONAB (Q5R966    ), 
ZFN2A_RAT   (Q5U2P3    ), ZFN2B_HUMAN (Q8WV99    ), ZFN2B_MOUSE (Q91X58    ), 
ZFN2B_RAT   (Q4KLG9    )
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PDB
[Detailed view]
9 PDB

1WFE; 1WFH; 1WFL; 1WFP; 1WG2; 1WYS; 1X4V; 1X4W; 5IJ4

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