PROSITE entry PS51044
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General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS51044 |
| Entry name [info] | ZF_SP_RING |
| Accession [info] | PS51044 |
| Entry type [info] | MATRIX |
| Date [info] |
01-DEC-2004 CREATED;
02-JUN-2021 DATA UPDATE; 18-JUN-2025 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51044 |
| Associated ProRule [info] | PRU00452 |
Name and characterization of the entry
| Description [info] | Zinc finger SP-RING-type profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=83; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=78; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2773535; R2=0.0080087; TEXT='-LogE'; /CUT_OFF: LEVEL=0; SCORE=1152; N_SCORE=11.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=528; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-35; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-255; BD=-255; /M: SY='P'; M= -58, -79, 49, 28, -80, 19, -64, -67, -60, -74, -11, -55, 59, 1, -67, 32, -56, 14, -85, -73; /M: SY='D'; M= -10, -81, 102, 54, -88, -68, -56, -86, -53, -83, -81, -43, -66, -50, -62, -57, -60, -81, -96, -73; /M: SY='D'; M= -21, 15, 70, 57, -80, -65, -59, -78, -55, -27, -73, -48, -66, -49, -62, 54, -53, -73, -89, -71; /M: SY='D'; M= -65, -83, 93, 67, -88, 3, -56, -88, -52, -84, -81, -45, -64, -49, -62, -57, -61, -83, -93, -74; /M: SY='I'; M= -63, -75, -87, -82, -51, -88, -80, 82, -78, 3, 61, -78, -77, -75, -79, -74, -59, 46, -78, -58; /M: SY='I'; M= 43, -74, -65, 34, -67, -6, -70, 48, -63, -53, 31, -66, -70, 28, -67, -57, -59, 18, -78, -66; /M: SY='M'; M= 2, -70, -69, 5, -62, -76, -70, 12, -64, -8, 54, -65, -71, 28, -68, -56, 49, 49, -82, -63; /M: SY='T'; M= -57, -69, -2, 27, -64, -3, -65, -59, -60, -21, -60, -54, -65, -60, -67, -46, 89, 0, -80, 19; /M: SY='S'; M= 25, -70, -60, -57, -78, 36, -63, -74, -56, -76, -67, -52, 39, 30, -6, 64, 8, -68, -78, -70; /M: SY='S'; M= -6, -67, 11, -63, -62, 3, -67, 11, -64, 20, -53, -55, -68, -61, -69, 51, 50, 9, -81, -64; /M: SY='Q'; M= -58, -75, -8, -48, -13, -67, -55, -70, 38, -70, -62, 4, -68, 64, 57, 30, 25, -21, -76, -61; /I: I=-26; MI=0; MD=-65; IM=0; DM=-65; /M: SY='V'; M= -57, -69, -78, -72, 11, -80, -74, 45, -70, 8, 34, -70, -75, 7, -72, -12, 17, 66, -77, -55; /M: SY='S'; M= -50, -68, 11, 12, -77, -12, -53, -77, -53, -80, -71, 77, -66, -48, -59, 80, -43, -72, -87, -69; /M: SY='L'; M= -67, -69, -80, -76, 39, -82, -65, -36, -75, 80, 36, 9, -83, -70, -73, -74, -62, -43, -67, -47; /M: SY='T'; M= -59, -72, -64, -56, -65, -72, -61, 26, 25, -6, 33, -55, -67, 38, 45, 5, 59, -51, -77, -61; /M: SY='C'; M= -62, 150, 16, -74, -72, -76, -78, -79, -75, -70, -70, -63, -89, -81, -81, -63, -61, -67,-101, -81; /M: SY='P'; M= -66, -92, -67, -55, -86, -68, -70, -74, -63, -84, -70, -73, 128, -66, -75, -64, -59, -79, -79, -83; /M: SY='I'; M= -65, -73, -81, -79, -46, -85, -73, 81, -76, 53, 39, -1, -77, -71, -77, -73, -60, -29, -73, -55; /M: SY='T'; M= -48, 24, -59, -62, -70, 10, -66, -62, -60, -67, -63, -48, -64, -59, -66, 66, 81, -1, -85, -67; /M: SY='C'; M= -62, 63, -65, -57, 34, 32, -60, -69, 56, -15, -60, -57, -73, 41, 12, -59, -63, -68, -65, 22; /M: SY='M'; M= -56, -70, -60, 5, -66, -68, -58, -58, 40, -11, 80, -54, -65, 19, 18, 33, 45, -58, -77, -61; /M: SY='R'; M= -66, -85, -56, 41, -79, -75, -55, -81, -32, -77, -67, -59, 61, -43, 96, -61, -63, -77, -77, -68; /M: SY='M'; M= -63, -73, -83, -77, -45, -82, -64, 62, -72, 25, 104, -75, -75, -66, -72, -72, -60, 5, -68, 31; /M: SY='K'; M= -56, -72, -55, 13, -74, -30, -60, -67, 69, -70, -63, -50, -63, 31, 2, 10, 58, -6, -78, -66; /I: I=-26; MI=0; MD=-65; IM=0; DM=-65; /M: SY='Y'; M= 0, -72, 8, -62, -52, -74, 32, 30, 25, 26, -46, 4, -73, -60, -60, -61, -5, 26, -70, 40; /M: SY='P'; M= 12, -87, -67, -56, -85, -65, -70, -73, -63, -82, -69, -72, 122, -66, -74, -60, -58, -75, -79, -82; /M: SY='C'; M= 16, 77, -75, -73, -62, 16, -76, 4, -71, -3, -51, -66, -76, -70, -75, 19, -53, 60, -83, -67; /M: SY='R'; M= -65, -80, -63, -50, -71, -76, -57, 6, 67, -16, -58, -56, -71, -43, 89, -61, -62, -64, -74, -62; /M: SY='S'; M= 20, 24, -58, -64, 32, 28, -61, -68, -61, -69, -65, 53, -70, -59, -66, 60, -6, -29, -75, -60; /M: SY='H'; M= -63, -75, -7, -9, -65, -74, 59, 1, 54, 12, 33, -55, -69, 28, 18, -59, 4, -4, -78, -57; /M: SY='D'; M= -8, -72, 50, -53, -9, -68, -63, -53, 9, -29, 12, 15, 38, 2, -61, -53, 41, 32, -83, -64; /M: SY='C'; M= -61, 154, -81, -81, -71, -77, -81, -78, -77, -69, -69, -67, -92, -85, -83, -64, -61, -66,-101, -82; /M: SY='K'; M= 11, -72, -58, -57, -73, 32, -61, -12, 52, -70, -63, 44, -68, -52, 28, -16, 10, -2, -78, -68; /M: SY='H'; M= -69, -81, -53, -53, -68, -71, 149, -86, -58, -68, -54, -43, -70, -47, -52, -59, -68, -86,-103, -37; /M: SY='M'; M= -61, -68, -78, -74, 12, -81, -71, 27, -72, 49, 57, -71, -75, -70, -73, -63, 44, 37, -74, -53; /M: SY='Q'; M= -62, -82, -62, -50, 21, 15, -47, -68, -51, -63, -56, -57, -73, 102, -51, -55, -64, -71, -51, 84; /M: SY='C'; M= -60, 130, 18, 61, -76, -74, -67, -81, -60, -73, -71, -59, -74, -59, -69, -15, -59, -70, -93, -78; /M: SY='F'; M= -70, -74, -67, 27, 102, -79, -62, -59, 38, -51, -56, -66, -75, -62, 16, -67, -64, -61, -51, -32; /M: SY='D'; M= -65, -80, 111, 28, -86, -64, -53, -85, -53, -83, -81, -37, -65, -51, -62, 2, -56, -81, -99, -70; /M: SY='A'; M= 73, -65, -73, -67, 14, 4, -70, -50, -68, 34, -49, -67, -72, -65, -71, -52, -57, 0, -71, -60; /M: SY='I'; M= -7, -74, -12, 37, -56, -77, -72, 68, -65, 18, -45, -67, -70, -61, -70, 3, -15, 5, 38, -59; /M: SY='W'; M= -2, -71, -67, -7, 15, -69, -66, -47, -63, 31, -50, 16, -73, 27, -66, 25, -3, 30, 81, -52; /M: SY='Y'; M= -68, -76, -67, -67, 70, -73, 36, -61, -55, -56, -55, 22, -79, -59, 45, -2, -62, -64, -46, 89; /M: SY='M'; M= -63, -70, -82, -76, -40, -83, -62, -7, -73, 61, 74, -78, -80, -68, -71, -72, -60, 37, -64, 54; /M: SY='Q'; M= -63, -78, -58, 35, -63, -76, 65, 49, -55, 15, 21, -5, -69, 73, -57, -61, -61, -49, -77, -56; /M: SY='M'; M= -59, -72, -62, 28, -58, -71, -57, -13, -58, 28, 92, 12, -70, 46, -60, 17, -56, -1, -77, -58; /I: I=-21; MD=-53; /M: SY='N'; M= -60, -72, 4, -56, -81, 5, -50, -80, -52, -84, -72, 102, -73, 38, -59, 27, -51, -80, -92, -73; D=-21; /I: I=-21; MI=0; MD=-53; IM=0; DM=-53; /M: SY='Q'; M= -69, 48, -60, 52, -84, -82, -67, -79, 29, -17, 7, -65, -75, 56, -57, -16, -15, -77, -88, -76; D=-21; /I: I=-21; DM=-53; /M: SY='R'; M= -73, -91, -64, 13, -90, -83, -63, -90, 54, -85, -74, -62, -77, 50, 69, -67, -72, -86, -84, -74; D=-21; /I: I=-21; DM=-53; /M: SY='K'; M= -62, -77, -60, -55, -67, -70, -58, -2, 70, -70, -63, 30, -71, -50, 32, 22, -10, -20, -73, 30; D=-21; /I: I=-21; DM=-53; /M: SY='P'; M= -63, -83, -63, -54, -81, 4, -65, -75, 39, -80, -68, -61, 102, -56, 29, -58, 14, -75, -78, -75; /M: SY='T'; M= -55, -66, -55, -54, -71, -66, -62, -66, 52, -69, -63, 17, -62, -52, 1, 10, 92, -59, -83, -66; /M: SY='W'; M= 31, 35, -88, -73, -50, -68, -86, -68, -64, -68, -68, -81, -77, -67, 13, -67, -73, -16, 158, -39; /M: SY='Q'; M= -61, 37, 17, -50, -66, -71, -54, -26, -3, -61, 40, 15, -71, 75, 40, -55, 8, 8, -74, 22; /M: SY='C'; M= -61, 154, -81, -81, -71, -77, -81, -78, -77, -69, -69, -67, -92, -85, -83, -64, -61, -66,-101, -82; /M: SY='P'; M= -66, -92, -67, -55, -86, -68, -70, -74, -63, -84, -70, -73, 128, -66, -75, -64, -59, -79, -79, -83; /I: I=-28; MI=0; MD=-71; IM=0; DM=-71; /M: SY='V'; M= 2, -71, -73, -74, -62, 53, 36, 35, -71, -51, -51, -63, -73, -70, -74, -58, -58, 65, -81, -63; /M: SY='C'; M= -61, 154, -81, -81, -71, -77, -81, -78, -77, -69, -69, -67, -92, -85, -83, -64, -61, -66,-101, -82; /M: SY='S'; M= -20, -71, 45, 4, -71, -61, -55, -64, -52, 5, -61, 48, -69, 38, 8, 52, -50, -14, -84, -65; /M: SY='H'; M= -8, -76, -57, -48, -75, -4, 84, -3, 68, -70, -60, -49, -66, 53, -41, 10, -58, -68, -78, -57; /I: I=-22; MD=-57; /M: SY='T'; M= -83, -98, 5, -83, -98, -94, -92, -81, -28, -92, -89, -3, 25, -87, -91, -13, 34, 10,-115, -96; D=-22; /I: I=-22; MI=0; MD=-57; IM=0; DM=-57; /M: SY='D'; M= -62, -77, 77, 29, -81, -16, 16, -81, 28, -80, -73, 38, 9, -48, 7, -14, -9, -78, -88, -68; /M: SY='M'; M= 15, -72, -71, -67, 22, -73, 9, 19, -63, 28, 55, 12, -76, 16, -6, -62, -59, 3, -64, 46; /I: I=-30; MI=0; MD=-77; IM=0; DM=-77; /M: SY='Q'; M= -16, 41, -64, -7, -65, -71, -58, -60, -48, 37, -51, -60, -4, 66, 51, 21, -58, -61, -76, -62; /M: SY='Y'; M= -8, -73, 16, -62, -3, -73, -58, 31, 18, 10, 33, 14, -74, -59, 5, -61, -19, 6, -64, 56; /M: SY='S'; M= -54, -73, 26, 42, -71, -65, -63, 38, -58, -63, -61, -54, 38, -53, -65, 63, -8, -12, -82, -67; /M: SY='D'; M= -59, -75, 81, -44, -74, -19, 12, 6, 3, -17, -65, -1, -68, 21, -59, 45, -52, -65, -87, -65; /M: SY='L'; M= -62, -72, -6, 18, -49, 0, -65, 21, -69, 59, 43, -71, -75, -63, -71, -68, -61, 15, -72, 10; /M: SY='I'; M= -65, -76, -70, 24, 30, -83, -67, 69, -1, 1, 47, -69, -73, -61, 9, -69, -60, -3, -66, 11; /M: SY='V'; M= -62, 38, -74, 0, 19, -81, -71, 40, -68, 34, -43, -73, 25, 32, -70, -67, -59, 41, -74, -56; /M: SY='D'; M= -65, -79, 107, -37, -81, -16, -55, -78, -53, -28, 4, -40, -68, -54, 14, -7, -57, -76, -95, -68; /M: SY='E'; M= -6, 47, 29, 54, -80, 18, -60, -15, -26, -73, -67, -1, 38, 40, -60, -53, -3, -69, -82, -72; /M: SY='Y'; M= 28, -72, -72, -68, -2, -72, -61, 51, 22, 14, 54, -9, -73, -61, -62, -62, -59, -42, -61, 56; /M: SY='L'; M= -67, -71, -85, -79, 52, -85, -69, 38, -77, 68, 56, -79, -81, -72, -75, -75, -63, -38, -64, -45; /M: SY='Q'; M= 25, -75, -56, 4, -69, -64, -54, -71, 39, -68, 32, 37, -68, 50, 43, -11, -57, -68, 41, 9; /M: SY='R'; M= -64, -78, -55, 24, 10, -22, 16, -15, 48, -69, -62, 32, -70, -45, 73, -58, -61, -70, -71, -2; /M: SY='C'; M= 17, 74, -71, 2, -61, -75, -71, 64, -62, -48, 42, -66, -72, 6, 3, -59, 12, -6, -79, -63; /M: SY='I'; M= -63, -72, -4, -30, -56, -75, -65, 50, 9, 42, -44, 23, -14, 19, -63, -59, 37, -43, -77, -60; /M: SY='E'; M= -22, -75, 28, 75, -80, -65, -54, -80, 32, -78, -71, 22, -61, -41, 8, 37, -53, -74, -82, -70; /M: SY='N'; M= -8, 11, 47, 27, -72, -61, -56, -11, -14, -7, -63, 52, -68, -50, 5, 46, -51, -64, -85, -67; /M: SY='H'; M= -8, 49, 0, -62, -57, -74, 62, -9, -64, 3, 50, -61, -74, 27, -65, -59, 15, 44, -80, 10; /M: SY='E'; M= -59, -77, -43, 70, -81, -23, -53, -79, 5, -77, -68, 47, -3, 49, 28, 3, -5, -75, -80, -69; /M: SY='Q'; M= -59, -77, 12, 42, -78, -37, 55, -10, 40, -72, -63, 6, -64, 61, -6, 28, -56, -70, -80, -62; /I: E1=0; IE=-255; DE=-255;» more |
Numerical results [info]
| Total number of hits | 32 in 32 different sequences |
| Number of true positive hits | 32 in 32 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | ZN_FING |
| Feature description [info] | SP-RING-type |
| Version [info] | 7 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
32 sequences
GEI17_CAEEL (Q94361), NSE2_ARATH (Q8GYH7), NSE2_BOVIN (Q32KY9), NSE2_HUMAN (Q96MF7), NSE2_MOUSE (Q91VT1), NSE2_RAT(Q4V8A0), NSE2_SCHPO (Q4PIR3), NSE2_XENLA (Q7ZXH2), NSE2_YEAST (P38632), PIAL1_ARATH (A0A0A7EPL0), PIAL2_ARATH (F4JYG0), PIAS1_HUMAN (O75925), PIAS1_MOUSE (O88907), PIAS2_HUMAN (O75928), PIAS2_MOUSE (Q8C5D8), PIAS2_RAT (Q6AZ28), PIAS3_HUMAN (Q9Y6X2), PIAS3_MOUSE (O54714), PIAS3_RAT (O70260), PIAS4_HUMAN (Q8N2W9), PIAS4_MOUSE (Q9JM05), PIS4A_DANRE (F1R4C4), PLI1_SCHPO (O94451), SIZ1_ARATH (Q680Q4), SIZ1_ORYSJ (Q6L4L4), SIZ1_YEAST (Q04195), SIZ2_ORYSJ (Q6ASW7), SIZ2_YEAST (Q12216), ZMIZ1_HUMAN (Q9ULJ6), ZMIZ1_MOUSE (Q6P1E1), ZMIZ2_HUMAN (Q8NF64), ZMIZ2_MOUSE (Q8CIE2)» more
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| PDB [Detailed view] |
17 PDB
2YU4; 3HTK; 3I2D; 4FO9; 4MVT; 5JNE; 6U75; 7P47; 7QCD; 7YLM; 7YQH; 8I21; 8I4U; 8I4V; 8I4X; 8WJL; 8WJO » more |