PROSITE entry PS51134
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General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS51134 |
| Entry name [info] | ZF_TFIIB |
| Accession [info] | PS51134 |
| Entry type [info] | MATRIX |
| Date [info] |
01-JUN-2005 CREATED;
10-MAY-2017 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51134 |
| Associated ProRule [info] | PRU00469 |
Name and characterization of the entry
| Description [info] | Zinc finger TFIIB-type profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=32; /DISJOINT: DEFINITION=PROTECT; N1=4; N2=29; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.6841733; R2=0.0059513; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=2026.4241943; R2=1.5353535; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=1011; H_SCORE=3579; N_SCORE=7.7; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=810; H_SCORE=3270; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-13; D=-50; I=-50; B1=-200; E1=-200; MI=-105; MD=-105; IM=-105; DM=-105; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-105; BD=-105; /M: SY='E'; M= -3, -22, 5, 20, 6, -1, 3, -9, 0, -12, -6, 5, 11, 3, -4, 6, 0, -9, -20, 1; /M: SY='P'; M= -1, -23, 2, 7, -20, 0, -6, -4, 14, -12, -8, -3, 21, 7, 7, 3, 2, 0, -27, -15; /M: SY='R'; M= -6, -1, -3, 5, -9, -23, 10, 3, 5, 6, 6, -9, -20, 15, 20, -8, -7, 5, -22, 2; /M: SY='R'; M= -1, 1, -12, -2, -6, -8, -12, 4, 13, -6, -1, -6, -17, 6, 13, -2, 9, 7, 9, 0; /I: I=-15; MI=0; MD=-32; IM=0; DM=-32; /M: SY='C'; M= -79, 157, -99, -99, -89, -94, -99, -96, -94, -86, -87, -85,-109,-102,-101, -81, -79, -83,-119,-100; /M: SY='P'; M= -11, -33, -13, -3, -26, -15, -13, -19, 12, -24, -11, -13, 87, -9, -8, -3, -3, -22, -24, -17; /M: SY='E'; M= -2, -23, 23, 27, -19, -10, 3, -9, 4, -16, -9, 25, -14, 11, 0, -1, -4, -10, -28, -6; /M: SY='C'; M= -10, 118, -25, -25, -19, -24, 25, -27, -22, -17, -15, -12, -37, -27, -27, -11, -10, -16, -49, -22; /I: I=-13; MI=0; MD=-27; IM=0; DM=-27; /M: SY='G'; M= -5, -30, 7, 1, -25, 39, -10, -34, -2, -32, -23, -1, 24, -4, -4, -3, -13, -30, -28, -23; D=-13; /I: I=-13; DM=-27; /M: SY='S'; M= 2, -6, 18, 4, -25, 10, -3, -22, -2, -25, -18, 9, 18, 1, -10, 26, 11, -16, -32, -17; /M: SY='P'; M= 8, -19, 5, 4, -24, 14, -11, -18, 4, -21, -14, 5, 22, 2, 3, 9, 15, -11, -29, -18; /M: SY='N'; M= -62, -16, 55, 35, -92, -82, 41, 5, -30, -48, -82, 66, 6, 11, -48, 8, -24, -38,-105, -83; /M: SY='I'; M= -12, -19, -32, -26, 30, -34, -22, 40, -23, 31, 20, -26, -27, -21, -18, -21, -8, 24, -18, 2; /M: SY='V'; M= -4, -20, -6, 4, -5, -30, -24, 31, -14, 9, 7, -17, -20, -12, -16, -11, 0, 32, -30, -10; /M: SY='E'; M= -7, -21, 2, 22, 1, -18, -2, -5, 5, -6, -6, -4, -14, 2, 8, 0, 10, 1, -17, 13; /M: SY='D'; M= -14, -28, 68, 23, -34, -12, 6, -33, -1, -31, -29, 25, -14, 0, 6, -2, -5, -30, -48, -17; /I: I=-14; MD=-29; /M: SY='Y'; M= -9, -25, -4, 1, 15, -16, 27, -9, -7, -5, -4, -1, 10, -5, -4, -3, -3, -12, -2, 40; D=-14; /I: I=-14; MD=-29; /M: SY='E'; M= 10, -22, 6, 22, -28, -6, -6, -26, 12, -24, -17, 2, -13, 11, 18, 13, -2, -18, -28, -18; D=-14; /I: I=-14; MI=-29; IM=-29; DM=-29; /M: SY='R'; M= 9, -21, -6, 1, -22, -8, 35, -24, 15, -21, -10, 8, -17, 8, 35, 7, -1, -17, -29, -8; /I: I=-11; MI=0; MD=-23; IM=0; DM=-23; /M: SY='G'; M= 9, -23, -12, -22, -31, 70, -19, -36, -17, -32, -22, 3, -17, -14, -24, 4, -14, -28, -23, -26; D=-11; /I: I=-11; DM=-23; /M: SY='D'; M= -12, -28, 50, 40, -26, -18, -1, -30, -3, -26, -23, 10, -11, 10, -5, -3, -5, -26, -31, -5; D=-11; /I: I=-11; DM=-23; /M: SY='M'; M= 0, -17, -20, -18, 1, -22, 0, 15, -14, 16, 19, -10, -20, -12, -11, -4, 11, 12, -22, 5; D=-11; /I: I=-11; DM=-23; /M: SY='V'; M= -6, -18, -30, -26, 13, -33, -27, 36, -23, 15, 11, -24, -25, -24, -25, -6, 0, 45, -21, -6; /M: SY='C'; M= -79, 157, -99, -99, -89, -94, -99, -96, -94, -86, -87, -85,-109,-102,-101, -81, -79, -83,-119,-100; /M: SY='G'; M= 10, -39, -5, 6, -23, 17, -11, -15, 7, -19, -10, 2, 13, 4, 0, 11, 12, -10, -26, -17; /M: SY='D'; M= -1, -22, 33, 21, -27, -4, -3, -21, 10, -23, -17, 19, -13, 7, 8, 6, 0, -14, -33, -17; /M: SY='C'; M= -79, 157, -99, -99, -89, -94, -99, -96, -94, -86, -87, -85,-109,-102,-101, -81, -79, -83,-119,-100; /M: SY='G'; M= 8, -34, -4, -21, -31, 75, -18, -38, -17, -33, -23, 2, -16, -14, -24, 3, -15, -31, -22, -25; /M: SY='C'; M= -4, 31, -22, -18, 8, -23, -13, 11, -15, 25, 10, -16, -25, -8, -10, -2, 3, 9, -17, 10; /M: SY='V'; M= -1, -15, -31, -26, -1, -33, -34, 36, -23, 4, 11, -36, -26, -25, -25, -15, 1, 50, -34, -9; /M: SY='I'; M= -8, -18, -40, -26, 4, -34, -26, 34, -24, 29, 17, -26, -26, -22, -25, -18, -1, 32, -26, -5; /M: SY='E'; M= 1, -25, 23, 47, -30, 20, -6, -30, 7, -25, -20, 1, -9, 12, -4, 1, -3, -23, -28, -20; /I: E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
| Total number of hits | 78 in 78 different sequences |
| Number of true positive hits | 78 in 78 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 9 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 89.66 % |
Comments [info]
| Taxonomic range [info] | Archaea, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | window20 |
| Author [info] | N_Hulo |
| Feature key [info] | ZN_FING |
| Feature description [info] | TFIIB-type |
| Version [info] | 5 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
78 sequences
BRF2_BOVIN (Q29S07), BRF2_DANRE (A8KBY2), BRF2_HUMAN (Q9HAW0), BRF2_MACFA (Q4R318), BRF2_MOUSE (Q3UAW9), BRF2_RAT(Q4V8D6), BRF2_XENLA (Q66IW8), BRF2_XENTR (A4QNR3), PBRP2_ARATH (Q9LIA6), TF2B1_ARATH (P48512), TF2B1_HALSA (Q9HNA2), TF2B1_THEAC (Q9HJM7), TF2B1_THEKO (Q5JGN1), TF2B1_THEVO (Q979Q3), TF2B2_ARATH (Q9SS44), TF2B2_HALSA (Q9HRE6), TF2B2_HALVD (Q9YGA5), TF2B2_SACS2 (P58110), TF2B2_THEAC (Q9HJM2), TF2B2_THEKO (P58109), TF2B2_THEVO (Q979P7), TF2B3_HALSA (Q9HHK5), TF2B4_HALSA (Q9HR45), TF2B6_HALSA (Q9HSB3), TF2B7_HALSA (Q9HSF7), TF2B_ARCFU (O28970), TF2B_BOVIN (Q2KIN8), TF2B_CAEEL (O16991), TF2B_CALMQ (A8MCX6), TF2B_DICDI (Q54FD6), TF2B_DROME (P29052), TF2B_DROVI (Q9NHP7), TF2B_ENCCU (Q8SRP3), TF2B_HUMAN (Q00403), TF2B_IGNH4 (A8AC96), TF2B_KLULA (Q05959), TF2B_MACFA (Q4R3J5), TF2B_META3 (A6UW60), TF2B_METAC (Q8TT29), TF2B_METB6 (A7IAR4), TF2B_METJA (Q58192), TF2B_METKA (Q8TX21), TF2B_METM5 (A4G0F2), TF2B_METM6 (A9A8Q0), TF2B_METM7 (A6VI28), TF2B_METMA (P0CW15), TF2B_METMJ (A3CSQ6), TF2B_METMP (Q6M176), TF2B_METMZ (P0CW14), TF2B_METPE (B8GJQ9), TF2B_METS3 (A5UKA1), TF2B_METST (Q2NEL6), TF2B_METTH (O26971), TF2B_METTL (Q9P9I7), TF2B_METTP (A0B5T8), TF2B_MOUSE (P62915), TF2B_ORYSJ (Q8W0W3), TF2B_PONAB (Q5R886), TF2B_PYRAB (Q9V0V5), TF2B_PYRAE (Q8ZWS3), TF2B_PYRAR (A4WMA6), TF2B_PYRFU (P61998), TF2B_PYRHO (O59151), TF2B_PYRIL (A1RV37), TF2B_PYRNV (B1YCX0), TF2B_PYRWO (P61999), TF2B_RAT(P62916), TF2B_SCHPO (O13749), TF2B_SOYBN (P48513), TF2B_XENLA (P29054), TF2B_YEAST (P29055), TF3B_CANAL (P43072), TF3B_HUMAN (Q92994), TF3B_KLULA (P46070), TF3B_MOUSE (Q8CFK2), TF3B_SCHPO (Q9P6R0), TF3B_YEAST (P29056), YTF2_SACSH (P46221)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
9 sequences
LYSW_SACS2 (Q980W8), LYSW_SULAC (Q4JAQ0), LYSW_SULTO (Q976J8), LYSW_THET8 (Q5SH22), PBRP1_ARATH (O23215), PTF2_ARATH (O81787), TF2B5_HALSA (Q9HHH8), TF2B_MIMIV (Q5UPT1), TF2B_TRYBB (Q257B3)» more |
| PDB [Detailed view] |
103 PDB
1DL6; 1PFT; 1RLY; 1RO4; 3K1F; 3K7A; 3VPB; 3WWL; 4BBR; 4BBS; 4V1N; 4V1O; 5FMF; 5FYW; 5FZ5; 5IY6; 5IY7; 5IY8; 5IY9; 5IYA; 5IYB; 5IYC; 5IYD; 5OQJ; 5OQM; 5SVA; 6CNB; 6CNC; 6CND; 6CNF; 6EU0; 6F40; 6F41; 6F42; 6F44; 6GYK; 6GYL; 6GYM; 6O9L; 7EDX; 7EG7; 7EG8; 7EG9; 7EGA; 7EGB; 7EGC; 7ENA; 7ENC; 7LBM; 7ML0; 7ML1; 7ML2; 7ML4; 7NVR; 7NVS; 7NVT; 7NVU; 7NVY; 7NVZ; 7NW0; 7O4I; 7O4J; 7O72; 7O73; 7O75; 7Q5B; 7UI9; 7UIF; 7UIO; 7ZS9; 7ZSA; 7ZSB; 7ZWC; 7ZWD; 7ZX7; 7ZX8; 7ZXE; 8BVW; 8BYQ; 8BZ1; 8CEN; 8CEO; 8FFZ; 8GXQ; 8GXS; 8ITY; 8IUE; 8IUH; 8S51; 8S52; 8S5N; 8UMH; 8UMI; 8UOQ; 8UOT; 8WAK; 8WAL; 8WAN; 8WAO; 8WAP; 8WAQ; 8WAR; 8WAS » more |