ProRule PRU00469
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PURL: https://purl.expasy.org/prosite/rule/PRU00469
        General rule information
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    | Accession | PRU00469 | 
| Dates | 10-AUG-2005 (Created) 19-NOV-2022 (Last updated, Version 9) | 
| Data class | Domain; | 
| Predictors | PROSITE; PS51134; ZF_TFIIB | Name | Zinc finger TFIIB-type | 
| Function | The zinc finger contacts the rbp1 subunit of Pol II through its dock domain | 
| Scope(s) | Eukaryota Archaea | 
| Example(s) | Q00403 (TF2B_HUMAN); | 
        Propagated annotation
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    Keywords
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    | Zinc-finger | |
| case <Feature:PS51134:5=[CH]> and <Feature:PS51134:8=[HC]> and <Feature:PS51134:24=[CH]> and <Feature:PS51134:27=[CH]> | |
| Zinc | |
| Metal-binding | |
| end case | |
    
    Features
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    | From: PS51134 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| case <Feature:PS51134:5=[C]> and <Feature:PS51134:8=[CH]> and <Feature:PS51134:24=[C]> and <Feature:PS51134:27=[C]> | ||||||||||||
| ZN_FING | from | to | /note="TFIIB-type #" | |||||||||
| else case <Feature:PS51134:5=[CH]> and <Feature:PS51134:8=[HC]> and <Feature:PS51134:24=[CH]> and <Feature:PS51134:27=[CH]> | ||||||||||||
| ZN_FING | from | to | /note="TFIIB-type #; atypical" | |||||||||
| else | ||||||||||||
| ZN_FING | from | to | /note="TFIIB-type #; degenerate" | |||||||||
| end case | ||||||||||||
| BINDING | 5 | 5 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" | [CH] | 1 | |||||||
| BINDING | 8 | 8 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" | [CH] | 1 | |||||||
| BINDING | 24 | 24 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" | [CH] | 1 | |||||||
| BINDING | 27 | 27 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" | [CH] | 1 | |||||||
    
    Additional information
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    | Size range | 18-33 amino acids | 
| Related rules | None | 
| Fusion | None | 
| Repeats | 1 | 
| Topology | Undefined | 
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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