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PROSITE entry PS51144


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PURL: https://purl.expasy.org/prosite/signature/PS51144

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General information about the entry

Entry name [info] ALPHA_CA_2
Accession [info] PS51144
Entry type [info] MATRIX
Date [info] 01-AUG-2005 CREATED;
01-OCT-2013 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00146
Associated ProRule [info] PRU01134

Name and characterization of the entry

Description [info] Alpha-carbonic anhydrases profile.
Matrix / Profile [info] 
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=260;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=260;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.9501495; R2=0.0211097; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=1005.7357178; R2=18.2132130; TEXT='Heuristic 0.1%';
/CUT_OFF: LEVEL=0; SCORE=263; H_SCORE=5796; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=169; H_SCORE=4084; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-10; D=-50; I=-50; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105;

...
 
                A   B   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y   Z
/I:         B1=0; BI=-105; BD=-105;
/M:         M= -6,-12,-21,-13,-10,-10,-13, -8,-13,-12,-16, -9,-10, -9, -7,-16, -2, -7,-10,-23, -8,-10;
/M: SY='E';  M= -4,  2,-24,  4,  5,-23,-11,  0,-21, -4,-27,-19,  0,-13,  1, -9,  5, -3,-18,-28,-14,  3;
/M: SY='W';  M=-25,-36,-20,-43,-28, 22,-30,-11,-14,-28,-13,-14,-34,-38,-22,-28,-25,-25,-22, 64, 29,-28;
/M: SY='G';  M= -4,  0,-11, -2, -9,-26,  4,-14,-23,-11,-28,-21,  2,-19,-11,-15,  4, -4,-19,-32,-23,-11;
/M: SY='Y';  M=-16,-27,-20,-27,-17, 19,-27, 11,-10,-17, -9, -9,-19,-26,-17,-16,-17,-17,-10,  8, 47,-17;
/M: SY='S';  M= -2,  2,-24,  2,  3,-26,  0, -9,-26,  0,-30,-20,  3,-12,  0, -7,  8, -3,-21,-32,-22,  1;
/I:         I=-7; MD=-15;
/M: SY='S';  M= -5, -4,-24, -2,  0,-22,  1,-11,-20, -8,-23,-16, -3,-12, -4,-12,  3, -7,-18,-29,-19, -2; D=-7;
/I:         I=-7; MI=0; MD=-15; IM=0; DM=-15;
/M:         M= -6, -9,-10,-11, -6,-16,-16, -6,-13, -5,-15,-12, -8,-11, -4, -8, -4, -5,-10,-21, -9, -6; D=-7;
/I:         I=-7; DM=-15;
/M: SY='N';  M= -9, -4,-12, -9, -7,-16,-18, -3,-10, -6,-14, -9,  1,-17, -5,-10, -4, -5, -9,-25,-11, -7; D=-7;
/I:         I=-7; DM=-15;
/M: SY='G';  M= -3, -2,-28, -2, -9,-28, 33,-13,-34,-11,-35,-25, -1,-16,-10,-13,  2,-14,-27,-30,-26,-10; D=-7;
/I:         I=-7; DM=-15;
/M: SY='P';  M= -9,-15,-28,-16, -8,-31,-12,-15,-26,-10,-25,-21,-15, 39, -5,-15, -7,-10,-18,-34,-24, -7;
/I:         I=-14; MD=-29;
/M: SY='E';  M= -6,  3,-26,  7,  9,-24,-14, -5,-21, -3,-25,-17,  0, -9,  1, -7,  3, -4,-19,-32,-17,  5; D=-14;
/I:         I=-14; MD=-29;
/M: SY='H';  M=-10,  0,-24, -4, -1,-15,-17,  8,-19, -2,-21,-14,  5,-18,  1, -2,  0, -4,-18,-25, -7, -2; D=-14;
/I:         I=-14; MI=-29; IM=-29; DM=-29;
/M: SY='W';  M=-28,-39,-19,-49,-30, 10,-30,-20,-18,-30,-18,-18,-39,-39,-20,-29,-29,-29,-28, 92, 19,-30;
/M: SY='G';  M=  1, -8,-22,-10, -8,-25,  4,-11,-23, -8,-27,-19, -4, -3, -7,-11,  3, -5,-17,-31,-21, -8;
/M:         M= -8, -3,-25, -4, -1,-24, -8,-10,-19, -3,-20,-15, -2,-13, -3, -7, -1, -2,-16,-31,-20, -3;
/I:         I=-6; MD=-13;
/M:         M= -8,-15,-16,-16,-12,-10,-18,-14,  0, -8, -1, -2,-13,-17, -8,-11, -9, -6,  0,-21,-10,-11; D=-6;
/I:         I=-6; MD=-13;
/M: SY='Y';  M= -8, -9,-16,-11, -8, -1,-15,  0,-12, -9,-15,-11, -5,-15, -9,-12, -4, -8,-11,-12,  8, -9; D=-6;
/I:         I=-6; MD=-13;
/M: SY='P';  M= -4,-11,-21,-12, -6,-26,-11,-11,-21, -5,-21,-19, -9, 29, -5, -9, -3, -4,-14,-29,-20, -6; D=-6;
/I:         I=-6; MI=0; MD=-13; IM=0; DM=-13;
/M:         M= -1,-13,-16,-14, -7,-14,-19,-13, -5, -7, -8, -1,-10,-17, -3,-10, -1,  0, -3,-25,-13, -7; D=-6;
/I:         I=-6; DM=-13;
/M: SY='C';  M=  5,-27, 72,-35,-33,-20,-25,-27,-11,-24,-12,-18,-26,-26,-25,-33, -5, -8, -9,-21,-20,-33; D=-6;
/I:         I=-6; DM=-13;
/M: SY='G';  M=  0, -3,-20, -6, -8,-23,  9,-11,-24, -7,-27,-18,  2,-17, -7,-10,  5, -6,-19,-30,-20, -8; D=-6;
/I:         I=-6; DM=-13;
/M: SY='G';  M=  0, -8,-29, -8,-15,-29, 49,-17,-37,-17,-38,-28, -7,-19,-17,-18,  1,-17,-28,-30,-28,-16;
/M: SY='K';  M= -9, -1,-27, -4,  4,-24,-18, -6,-23, 10,-22,-14,  2,-11,  5,  5,  0, -3,-19,-30,-17,  3;
/M: SY='R';  M=-11,-10,-29,-17, -1,-17,-22,  0,-20, 10,-15, -9, -4,-19,  5, 17, -8, -9,-18,-23, -9, -1;
/M: SY='Q';  M=-10, -1,-30, -1, 18,-30,-20, 10,-30,  9,-21, -2, -1, -5, 55,  8, -1,-10,-20,-21,-20, 27;
/M: SY='S';  M= 11,  0,-10,  0,  0,-20,  0,-10,-20,  0,-30,-20,  9,-10,  0,-10, 39, 10,-20,-30,-20,  0;
/M: SY='P';  M=-10,-20,-30,-20,-10,-40,-20,-20,-30,-10,-30,-30,-20, 80,-10,-20,-10,-10,-20,-40,-30,-10;
/M: SY='I';  M= -9,-30,-10,-30,-30,  0,-39,-30, 38,-29, 18, 10,-30,-29,-29,-30,-20, -9, 31,-21, -9,-29;
/M: SY='N';  M=-14, 28,-31, 27,  8,-32, -9, -1,-28, -5,-37,-23, 29,-18,  0,-10,  7, -3,-27,-42,-23,  4;
/M: SY='I';  M=-12,-32,-11,-33,-30,  2,-39,-29, 33,-29, 23, 13,-32,-30,-27,-28,-22,-10, 24,-19, -9,-29;
/I:         I=-12; MI=0; MD=-25; IM=0; DM=-25;
/M:         M= -8, -7,-21, -7, -4,-21,-20, -7,-12, -7,-16,-11, -5, -8, -1,-11, -4, -2, -8,-29,-15, -3;
/M: SY='T';  M= -6, -9,-21, -8, -4,-22,-18,-14,-14, -7,-15,-11, -8, -4, -3, -9,  0,  7, -9,-28,-18, -4;
/M: SY='S';  M= -3, -2,-20, -3,  1,-22,-11, -5,-21,  1,-24,-17, -1,-15, -1, -2,  4, -5,-18,-29,-15, -1;
/M: SY='N';  M= -9,  2,-27,  0,  1,-25,-13, -4,-20,  0,-22,-14,  4,-18,  3,  2,  0, -4,-18,-32,-19,  0;
/M: SY='V';  M=  9,-25, -8,-25,-20,-11,-20,-24,  8,-17,  2,  4,-23,-18,-14,-19, -6,  2, 12,-27,-14,-17;
/M: SY='Q';  M= -6,-15,-18,-17, -7,-17,-24,-13, -5, -3, -6, -2,-13,-16,  2, -4, -7, -3, -2,-26,-15, -5;
/M: SY='Y';  M=-10,-17,-21,-20,-11,  3,-24, -6, -8,-10,-10, -7,-15,-21,-10,-12,-11,-10, -8,-14,  6,-11;
/M: SY='D';  M=-10,  5,-25,  8, -2,-28, -8,-12,-19, -9,-23,-15,  0,-17, -4,-12, -4, -8,-16,-36,-23, -4;
/M: SY='P';  M= -4, -7,-22, -8,  2,-25,-16, -5,-22, -2,-24,-18, -4,  7,  2, -6,  2, -4,-18,-30,-17,  1;
/I:         I=-5; MI=0; MD=-10; IM=0; DM=-10;
/M: SY='N';  M= -3,  3,-17,  1,  1,-17, -2, -3,-18,  1,-20,-13,  7,-10,  2, -1,  5, -1,-15,-21,-13,  1; D=-5;
/I:         I=-5; DM=-10;
/M: SY='L';  M=-14,-31,-12,-32,-25,  0,-31,-21, 13,-24, 23, 13,-29,-26,-16,-18,-22, -9,  7,-19, -7,-24; D=-5;
/I:         I=-5; DM=-10;
/M: SY='P';  M= -3, -6,-22, -7,  1,-25,-13,-10,-20,  2,-21,-14, -5,  3,  3, -3,  2,  1,-14,-29,-20,  1; D=-5;
/I:         I=-5; DM=-10;
/M: SY='P';  M= -6, -6,-28, -7,  4,-32,-15,-11,-27,  2,-28,-22, -6, 23,  3, -5,  0, -6,-21,-34,-24,  3;
/M: SY='L';  M=-16,-35,-12,-38,-29, 10,-36,-25, 17,-28, 24, 14,-35,-31,-22,-24,-25,-11, 10,-12, -2,-28;
/M: SY='Q';  M=-10, -2,-27, -5,  2,-21,-15,  1,-20,  1,-21,-14,  3,-17,  5,  3,  0, -5,-18,-28,-14,  2;
/M: SY='F';  M=-18,-33,-16,-37,-27, 21,-33,-18,  8,-27, 12,  6,-31,-31,-22,-24,-23,-14,  1,  0, 10,-27;
/I:         I=-8; MD=-17;
/M: SY='E';  M= -8, -1,-23, -2,  4,-21,-18, -7,-16,  0,-17,-11,  0,-14,  3, -4,  1,  0,-14,-29,-17,  3; D=-8;
/I:         I=-8; MD=-17;
/M: SY='G';  M=-10, -7,-24, -9,-10,-13,  2, -3,-22,-12,-23,-17, -1,-15,-11,-12, -4,-11,-18,-19, -2,-11; D=-8;
/I:         I=-8; MD=-17;
/M: SY='Y';  M=-12,-17,-14,-18,-13, 13,-16,  4, -7,-12, -7, -5,-13,-20,-12,-13,-11,-12, -8,  5, 25,-13; D=-8;
/I:         I=-8; MD=-17;
/M: SY='D';  M= -7,  6,-16,  9,  4,-13, -6, -1,-14, -4,-16,-10,  1,-11,  1, -8, -1, -6,-13,-17, -7,  2; D=-8;
/I:         I=-8; MI=0; MD=-17; IM=0; DM=-17;
/M:         M= -7, -4,-23, -3, -3,-17,-11, -9,-15, -8,-18,-12, -5,-15, -5,-11, -3, -7,-12,-26,-11, -4; D=-8;
/I:         I=-8; DM=-17;
/M: SY='Q';  M= -8, -6,-24, -7, -2,-21,-18, -8,-16, -4,-16,-11, -4, -6,  1, -6, -2, -4,-13,-29,-17, -2; D=-8;
/I:         I=-8; DM=-17;
/M: SY='P';  M= -3,-11,-17,-13, -7,-22,-14,-14,-16, -7,-18,-14,-10,  2, -5,-11, -1, -1,-12,-29,-19, -7; D=-8;
/I:         I=-8; DM=-17;
/M:         M= -2, -9,-21, -8, -4,-19,-11,-12,-13, -6,-17,-11, -8,-14, -4, -8,  0, -3, -9,-28,-16, -5;
/M: SY='S';  M= -5,  0,-22, -2,  3,-25,-14, -8,-22,  2,-25,-16,  3, -6,  3, -4,  5, -3,-19,-31,-19,  2;
/M:         M= -4,-22,-13,-25,-18, -9,-18,-20, -4,-15, -4, -4,-20,-19,-13,-16, -9, -3, -2,-16,-11,-17;
/M: SY='T';  M= -8, -5,-21, -5, -2,-20,-20,-12,-11, -4,-14,-10, -2,-15, -1, -6,  1,  4, -9,-28,-17, -2;
/M: SY='I';  M=-11,-31,-12,-32,-27,  0,-34,-26, 22,-24, 19, 16,-29,-27,-19,-24,-21, -7, 18,-21, -7,-25;
/M: SY='T';  M= -6,-15,-18,-17, -8,-14,-25,-15, -2, -5, -5, -4,-13,-17, -6, -9, -6,  5,  1,-24,-12, -7;
/M: SY='N';  M=-20, 28,-30, 10,  0,-29,-11,  9,-29, -1,-39,-20, 55,-20, -1, -1,  9, -1,-28,-39,-19,  0;
/M: SY='N';  M=-12,  9,-25,  1, -1,-25,-16,  1,-21, -3,-25,-16, 22,-16, -2, -1,  5,  8,-18,-34,-18, -2;
/M: SY='G';  M= -1, -9,-30, -8,-15,-30, 48,-18,-37,-17,-37,-27, -9,-17,-15,-18,  0,-18,-27,-30,-29,-15;
/M: SY='H';  M=-17, -4,-26,-12, -3,-11,-20, 39,-23, -7,-23,-15,  3,-21,  6, -2, -9,-15,-23,-16,  8, -2;
/M: SY='T';  M= -2, -5,-15, -5, -7,-19,-12,-13,-15, -8,-18,-13,  0,-15, -7,-11,  9, 19, -9,-29,-17, -7;
/I:         I=-5; MI=0; MD=-11; IM=0; DM=-11;
/M: SY='V';  M= -3,-28,-10,-29,-25, -5,-28,-25, 19,-20,  7,  7,-26,-19,-19,-24,-16, -3, 22,-23, -9,-21; D=-5;
/I:         I=-5; DM=-11;
/M: SY='Q';  M= -5,-12,-21,-13, -2,-18,-20, -9,-10, -2,-10, -1,-10,-15, 10, -4, -4, -6, -6,-22,-15,  1; D=-5;
/I:         I=-5; DM=-11;
/M: SY='I';  M=-10,-32,-11,-33,-29,  1,-33,-26, 22,-25, 16, 14,-31,-27,-21,-27,-22, -8, 21,-18, -5,-25;
/M: SY='N';  M= -8, -1,-24, -4, -1,-23,-17, -9,-17,  0,-18,-13,  4,-17,  0,  2,  2,  4,-15,-31,-19, -1;
/M: SY='F';  M=-12,-30,-15,-34,-26,  9,-29,-21,  8,-24,  8,  5,-29,-26,-20,-22,-20,-12,  4, -8,  0,-24;
/M: SY='E';  M=-11,  4,-31,  3,  5,-29, -9, -7,-28,  1,-31,-23,  3,  0, -1, -5, -1, -8,-24,-34,-21,  2;
/I:         I=-7; MI=0; MD=-15; IM=0; DM=-15;
/M: SY='D';  M= -3,  2,-12,  3,  3,-12, -6, -1,-12, -1,-14, -9,  2, -6,  2, -4,  3, -1,-10,-15, -7,  2; D=-7;
/I:         I=-7; DM=-15;
/M: SY='D';  M= -4,  1,-19,  2,  2,-20,  2, -6,-20, -4,-21,-15,  0, -9,  0, -6,  2, -6,-17,-23,-16,  0; D=-7;
/I:         I=-7; DM=-15;
/M: SY='D';  M= -7,  6,-25,  7,  3,-23, -6, -6,-22, -6,-27,-17,  6,-11, -2,-11,  3, -5,-19,-32,-19,  1; D=-7;
/I:         I=-7; DM=-15;
/M: SY='S';  M= -2, -6,-16, -7, -7,-23, -4,-12,-18, -8,-20,-13, -3,-15, -6, -9,  1, -4,-15,-30,-20, -8; D=-7;
/I:         I=-7; DM=-15;
/M: SY='P';  M= -3,-17,-19,-17,-13,-19,-10,-17,-12,-13,-16,-12,-14,  5,-12,-17, -3, -5, -7,-28,-16,-12;
/M: SY='T';  M= -7,-10,-16,-12, -7,-13,-18, -9,-12, -7,-14, -8, -5,-15, -6,-12,  0,  2,-10,-23, -7, -7;
/M: SY='I';  M= -9,-31,-11,-31,-26, -4,-35,-28, 25,-25, 20, 14,-30,-26,-20,-24,-20, -5, 21,-23,-11,-24;
/M: SY='S';  M= -2, -9,-17,-12, -5,-15,-16, -8,-13, -1,-17,-11, -3,-14, -1, -3,  7,  2,-11,-26,-14, -4;
/M: SY='G';  M= -4,-14,-24,-14,-20,-20, 21,-21,-15,-20,-20,-16,-14,-22,-20,-21, -6,-14,-11,-28,-22,-20;
/M: SY='G';  M=  1, -3,-26, -3,-10,-29, 30,-15,-32,-14,-35,-25, -3,-15,-12,-16,  3,-13,-24,-33,-27,-11;
/M: SY='P';  M= -5, -7,-27, -7, -8,-29,  5,-16,-27, -9,-29,-23, -7, 10, -9,-15, -2, -9,-20,-34,-25, -8;
/I:         I=-5; MD=-9;
/M: SY='L';  M=-16,-30,-13,-31,-22, -4,-34,-25, 11,-22, 23, 13,-29,-26,-15,-16,-21, -4,  6,-19,-11,-22; D=-5;
/I:         I=-5; MD=-9;
/M:         M= -7, -6,-26, -6,  0,-25,-12,-11,-20, -3,-21,-15, -5,  0, -1, -6, -1, -3,-16,-31,-19, -1; D=-5;
/I:         I=-5; MI=0; MD=-9; IM=0; DM=-9;
/M: SY='G';  M= -2, -5,-20, -5, -4,-18,  7, -2,-22, -7,-23,-16, -3,-12, -1, -7,  2, -6,-17,-21,-11, -4; D=-5;
/I:         I=-5; DM=-9;
/M: SY='R';  M= -6, -6,-20, -7,  0,-18,-17, -6,-12,  2,-14,-11, -4,-11,  1,  5, -3, -3,-10,-24,-13,  0; D=-5;
/I:         I=-5; DM=-9;
/M: SY='Y';  M=-18,-29,-19,-32,-22, 33,-29, 11, -7,-22, -7, -7,-22,-31,-21,-22,-19,-19, -9, 14, 54,-22;
/M: SY='K';  M=-10, -4,-29, -6,  5,-23,-21, -2,-20, 11,-20,-13, -3,-16,  8,  9, -4, -6,-16,-27,-13,  5;
/M: SY='L';  M= -3,-28,-11,-30,-22,  1,-25,-22,  4,-21,  7,  2,-27,-17,-17,-19,-12, -6,  2,-19, -6,-21;
/M:         M= -5,-10,-21,-10, -1,-19,-20, -8,-10, -3,-11, -8,-10,-17,  0, -5, -4, -4, -8,-28,-15, -1;
/M: SY='Q';  M= -8,  1,-30,  0, 16,-29,-15,  8,-29,  8,-23, -7,  3,-12, 41,  9,  1, -9,-22,-24,-19, 22;
/M: SY='F';  M=-14,-32,-14,-36,-29, 18,-34,-22, 16,-28, 18, 12,-32,-32,-24,-26,-22,-12,  9,-11,  3,-28;
/M: SY='H';  M=-18,  0,-29, -8,  0,-13,-20, 63,-28, -8,-28,-19,  9,-19,  8,  1, -8,-15,-27,-23, 12,  0;
/M: SY='F';  M=-19,-33,-16,-39,-28, 32,-32,-17,  3,-28,  6,  3,-32,-35,-24,-27,-23,-17, -5, 10, 16,-28;
/M: SY='H';  M=-20,  0,-30,-10,  0,-10,-20, 78,-30, -9,-30,-20, 10,-20, 10,  0,-10,-20,-30,-20, 19,  0;
/I:         I=-8; MD=-17;
/M: SY='W';  M=-20,-27,-15,-34,-21, 10,-21,-13,-13,-21,-13,-12,-26,-28,-14,-21,-20,-20,-20, 61, 15,-21; D=-8;
/I:         I=-8; MD=-17;
/M: SY='G';  M=  0, -7,-20, -7,-13,-20, 38,-13,-27,-12,-27,-20, -6,-13,-13,-12,  0,-13,-20,-20,-20,-13; D=-8;
/I:         I=-8; MD=-17;
/M: SY='S';  M= -1, -2,-13, -4, -1,-16, -4, -6,-15,  0,-17,-11,  1,-11,  1,  0,  5, -1,-13,-18,-13, -1; D=-8;
/I:         I=-8; MD=-17;
/M: SY='S';  M= -3, -3, -9, -5, -3,-16, -6, -8,-14, -5,-17,-13,  1, -6, -4, -7,  2, -1,-12,-19,-13, -4; D=-8;
/I:         I=-8; MI=0; MD=-17; IM=0; DM=-17;
/M: SY='D';  M= -6,  9,-19, 11,  5,-20, -2, -5,-18, -2,-22,-15,  8, -9, -1, -5,  4, -3,-16,-25,-16,  2; D=-8;
/I:         I=-8; DM=-17;
/M: SY='S';  M= -2, -2,-14, -3, -1,-13, -7, -3,-12, -5,-14, -8,  0,-10,  0, -6,  4,  0,-11,-19,-11, -1; D=-8;
/I:         I=-8; DM=-17;
/M: SY='S';  M= -5, -4,-21, -6,  0,-18,-15, -7,-18,  0,-22,-15, -1, -9,  0, -5,  4, -2,-16,-24,-14, -1; D=-8;
/I:         I=-8; DM=-17;
/M: SY='G';  M= -2,-14,-27,-14,-18,-29, 34,-20,-32,-18,-33,-25,-13, -1,-17,-19, -3,-15,-23,-29,-27,-18; D=-8;
/I:         I=-8; DM=-17;
/M: SY='S';  M= 10, -1,-11, -1,  0,-21, -1,-10,-20,  0,-29,-20,  9, -8,  1,-10, 37, 10,-19,-30,-20,  0;
/M: SY='E';  M=-10,  9,-40, 19, 49,-29,-20,  0,-29,  9,-29,-18,  0,-10, 20,  0,  0,-10,-29,-30,-20, 39;
/M: SY='H';  M=-20,  1,-30, -8,  0,-10,-20, 76,-30,-10,-30,-20,  9,-20,  9, -1,-10,-20,-30,-20, 19,  0;
/M: SY='T';  M=  0,-14,-10,-15,-11,-16,-19,-17, -7,-10, -7, -4, -7,-14, -7,-12,  6, 23, -2,-27,-17,-10;
/M: SY='I';  M=-10,-30,-12,-31,-28,  0,-35,-26, 26,-26, 18, 12,-30,-27,-23,-27,-22, -8, 23,-22, -7,-25;
/M: SY='D';  M=-15, 26,-33, 28,  9,-33, -5, -2,-30, -5,-38,-24, 24,-19, -1, -9,  4, -6,-28,-42,-24,  4;
/M: SY='G';  M= -3, -4,-29, -5,-13,-28, 40,-14,-36,-14,-37,-27, -3,-19,-14,-14,  2,-15,-28,-31,-26,-14;
/M: SY='R';  M= -8, -9,-26,-13,  0,-19,-22, -2,-14,  4,-15,-10, -6,-17,  5,  6, -6, -7,-11,-25,-11,  1;
/M: SY='R';  M= -5,-10,-27,-16, -4,-20,-16,  0,-21,  5,-18,-12, -4,-18,  4, 18, -4, -8,-19,-26,-13, -3;
/M: SY='Y';  M=-15,-26,-15,-30,-22, 27,-26,  0, -7,-22, -7, -6,-20,-29,-21,-22,-15,-15,-10,  6, 33,-22;
/M: SY='P';  M=  0,-13,-21,-12, -7,-31,-15,-18,-22,-10,-25,-21,-14, 33, -9,-15, -3, -6,-15,-36,-25, -8;
/M: SY='M';  M=  1,-28,-13,-28,-20, -9,-19,-23,  4,-18,  9, 19,-24,-23,-10,-15,-14, -8,  5,-24,-14,-19;
/M: SY='E';  M=-10,  9,-39, 18, 47,-30,-20,  1,-30,  9,-30,-20,  0, -9, 20,  1,  0,-10,-30,-30,-19, 38;
/I:         I=-14; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='M';  M= -7,-32,-12,-32,-25, -4,-30,-26, 15,-24, 21, 22,-30,-26,-15,-21,-20, -8, 12,-23,-12,-24;
/M: SY='H';  M=-17,  0,-29, -8,  4,-14,-20, 64,-30, -6,-28,-16,  8,-18, 19,  2, -7,-17,-28,-20, 11,  6;
/M: SY='I';  M=-11,-32,-10,-32,-28,  0,-36,-27, 24,-27, 21, 17,-31,-29,-21,-25,-22, -9, 19,-21, -9,-27;
/I:         I=-1; MI=0; MD=-2; IM=0; DM=-2;
/M: SY='V';  M= -4,-29,-11,-30,-27, -2,-29,-25, 22,-21,  8,  9,-28,-23,-20,-27,-18, -3, 27,-21, -3,-21; D=-1;
/I:         I=-1; DM=-2;
/M: SY='H';  M=-14, -6,-20,-14, -6, -7,-19, 46,-23,-12,-23,-14,  3,-21,  2, -6, -8,-15,-23,-17, 11, -6; D=-1;
/I:         I=-1; DM=-2;
/M: SY='Y';  M=-13,-18,-24,-22, -9, -3,-26, -4,-10, -4,-11, -8,-15,-23, -6, -4,-13,-11,-10, -6,  6, -9;
/I:         I=-2; MD=-4;
/M: SY='N';  M=-11, 14,-25,  5,  1,-27, -9,  0,-26,  3,-32,-19, 26,-17,  0,  0,  8, -2,-24,-34,-19,  0; D=-2;
/I:         I=-2; MD=-4;
/M: SY='T';  M= -3, -5,-19, -6,  0,-22,-15, -7,-17,  0,-19,-13, -1, -9,  1, -5,  5,  7,-12,-28,-16,  0; D=-2;
/I:         I=-2; MD=-4;
/M: SY='E';  M= -6,  6,-26, 10, 11,-28,-13, -8,-22,  4,-26,-17,  2,-12,  6, -1,  4, -1,-19,-32,-21,  8; D=-2;
/I:         I=-2; MD=-4;
/M: SY='Y';  M= -7,-10,-10,-11, -7, -1,-15, -5, -3, -6, -1, -2, -8,-13, -6, -7, -6, -3, -3, -9,  2, -8; D=-2;
/I:         I=-2; MD=-4;
/M: SY='Y';  M= -9,-12,-11,-14, -9, 12,-13,  6, -6,-10, -6, -5, -8,-15, -9,-10, -8, -8, -7,  4, 24, -9; D=-2;
/I:         I=-2; MI=0; MD=-4; IM=0; DM=-4;
/M: SY='S';  M= -1, -6,-18, -7, -4,-21, -2,-11,-18, -2,-19,-14, -4, -2, -2, -5,  1, -4,-13,-25,-18, -4; D=-2;
/I:         I=-2; DM=-4;
/M: SY='N';  M= -4,  6,-17,  2,  0,-20, -6, -4,-20, -1,-25,-16, 14,-10, -1, -5, 13,  5,-17,-25,-16,  0; D=-2;
/I:         I=-2; DM=-4;
/M: SY='L';  M= -9,-22,-10,-25,-19,  7,-24,-15,  6,-19,  8,  7,-19,-23,-14,-17,-13, -7,  3,-12,  0,-18; D=-2;
/I:         I=-2; DM=-4;
/M: SY='E';  M= -3,  2,-22,  5,  6,-23, -1, -8,-21, -2,-24,-17,  0, -7, -1, -7,  5, -1,-17,-27,-19,  3; D=-2;
/I:         I=-2; DM=-4;
/M: SY='E';  M= -3,  1,-22,  4, 14,-21,-12, -6,-18,  4,-19,-12, -1,-10,  6, -2,  2, -1,-15,-25,-17, 11; D=-2;
/I:         I=-2; DM=-4;
/M: SY='A';  M= 23,-13, -3,-14, -8,-18,  0,-15,-12, -7,-19,-11,-11, -6, -8, -9,  8,  0, -5,-25,-17, -8; D=-2;
/I:         I=-2; DM=-4;
/M: SY='V';  M= -1,-19, -7,-20,-14, -8,-17,-17,  2,-12,  2,  1,-18,-15,-10,-12, -8, -4,  3,-19,-11,-13; D=-2;
/I:         I=-2; DM=-4;
/M: SY='S';  M= -2, -1,-17, -3, -2,-20, -4, -8,-17,  0,-18,-12,  1,-10,  1, -3,  3, -1,-12,-24,-17, -2; D=-2;
/I:         I=-2; DM=-4;
/M: SY='Q';  M= -5,  1,-21, -1,  4,-19, -8, -1,-21,  4,-21,-12,  2,-12,  9,  1,  4, -5,-17,-22,-13,  5; D=-2;
/I:         I=-2; DM=-4;
/M: SY='P';  M= -4, -8,-20, -9, -3,-23,-11,-10,-19, -2,-21,-17, -6, 18, -4, -8,  2, -4,-15,-27,-18, -3; D=-2;
/I:         I=-2; DM=-4;
/M: SY='B';  M=-11, 11,-31, 11,  3,-27,  3, -2,-29, -6,-33,-22, 10,-18,  0, -6,  2, -7,-26,-33,-20,  0; D=-2;
/I:         I=-2; DM=-4;
/M: SY='G';  M= -4, -4,-24, -5, -9,-29, 26,-12,-34, -9,-34,-25, -4,-16, -7,-10,  0,-15,-27,-30,-25, -9; D=-2;
/I:         I=-2; DM=-4;
/M: SY='L';  M=-12,-33,-11,-35,-27,  5,-34,-24, 17,-26, 20, 10,-32,-28,-21,-22,-22,-10, 12,-15, -3,-26; D=-2;
/I:         I=-2; DM=-4;
/M: SY='A';  M= 22,-20, -5,-20,-13,-17, -8,-21, -5,-11,-11, -6,-19,-12,-10,-12,  4,  2,  2,-29,-18,-12; D=-2;
/I:         I=-2; DM=-4;
/M: SY='V';  M=  3,-28, -7,-28,-27,-11,-26,-28, 23,-19,  6,  7,-28,-20,-19,-27,-16, -1, 31,-28,-12,-20; D=-2;
/I:         I=-2; DM=-4;
/M: SY='I';  M=-11,-33,-10,-33,-28, -2,-35,-28, 25,-26, 24, 14,-32,-27,-21,-24,-22, -6, 20,-22,-10,-26; D=-2;
/I:         I=-2; DM=-4;
/M: SY='G';  M= 13,-12,-18,-11,-13,-25, 28,-18,-26,-13,-31,-21,-10,-13,-13,-15,  8, -9,-18,-30,-25,-13; D=-2;
/I:         I=-2; DM=-4;
/M: SY='I';  M= -6,-29,-12,-31,-27,  8,-30,-22, 19,-23,  8,  5,-28,-26,-23,-27,-17, -7, 19,-16,  2,-23; D=-2;
/I:         I=-2; DM=-4;
/M: SY='F';  M=-16,-31,-16,-35,-26, 24,-31,-17,  7,-26, 13, 11,-29,-32,-21,-24,-20,-11,  0, -6,  8,-26; D=-2;
/I:         I=-2; DM=-4;
/M: SY='F';  M=-16,-30,-16,-34,-27, 26,-32,-13, 10,-26,  9,  4,-29,-32,-23,-25,-20,-14,  4, -3, 17,-26; D=-2;
/I:         I=-2; DM=-4;
/M: SY='E';  M=-10,  6,-32,  6, 20,-29,-18,  0,-27, 14,-27,-16,  2,-11, 18,  6, -1, -9,-22,-30,-19, 19; D=-2;
/I:         I=-2; DM=-4;
/M: SY='I';  M= -8,-22,-17,-22,-15, -6,-28,-16,  9,-15,  3,  3,-21,-21,-13,-18,-15, -7,  9,-22, -5,-14; D=-2;
/I:         I=-2; DM=-4;
/M: SY='G';  M=  2, -6,-23, -4,-10,-26, 26,-17,-28,-12,-31,-23, -5,-16,-11,-14,  8, -5,-21,-31,-25,-11; D=-2;
/I:         I=-2; DM=-4;
/M: SY='E';  M= -6,  3,-26,  2,  6,-25,-10, -3,-24,  2,-27,-18,  5,-13,  2, -2,  3, -5,-21,-31,-18,  4; D=-2;
/I:         I=-2; DM=-4;
/M: SY='E';  M= -8, -2,-26, -1,  4,-20,-16, -6,-19, -3,-20,-14, -3,-13,  0, -6, -1, -4,-17,-27,-14,  1; D=-2;
/I:         I=-2; DM=-4;
/M: SY='D';  M= -4,  3,-17,  4,  4,-17, -7, -6,-13, -1,-16,-11,  1, -3,  1, -5,  2, -2,-11,-21,-14,  3; D=-2;
/I:         I=-2; DM=-4;
/M: SY='N';  M=-13, 20,-28, 12,  5,-29,-10,  3,-28,  0,-35,-20, 32,-16,  2, -4,  9,  0,-26,-37,-21,  4;
/M: SY='P';  M= -2, -8,-23, -9, -1,-27,-14,-13,-20, -1,-22,-16, -5,  8,  0, -6,  2,  1,-13,-32,-22, -1;
/I:         I=-12; MI=0; MD=-25; IM=0; DM=-25;
/M:         M= -5, -9,-23,-13, -5, -5, -8, -5,-19, -8,-21,-13, -6,-19, -8,-10, -3,-10,-18,-20, -5, -7;
/M: SY='L';  M=-17,-31,-13,-34,-26,  9,-33,-16,  8,-25, 13,  7,-27,-28,-20,-22,-22,-12,  3, -7,  8,-25;
/I:         I=-1; MI=0; MD=-2; IM=0; DM=-2;
/M: SY='Q';  M= -4,  5,-25,  5,  8,-26, -8, -6,-25,  5,-28,-17,  5,-14,  9, -1,  9, -2,-21,-31,-21,  7; D=-1;
/I:         I=-1; DM=-2;
/M: SY='Q';  M= -5, -8,-25, -9,  0,-23,-17, -6,-21,  0,-21,-13, -7,  0,  3, -1, -3, -2,-15,-29,-17,  0; D=-1;
/I:         I=-1; DM=-2;
/M: SY='I';  M=-11,-32,-11,-33,-28,  3,-36,-27, 26,-27, 20, 13,-31,-29,-24,-26,-21,-10, 19,-17, -6,-27; D=-1;
/I:         I=-1; DM=-2;
/M: SY='I';  M= -8,-22,-11,-23,-17, -6,-28,-21,  7,-16,  5,  3,-19,-21,-13,-18,-11,  1,  7,-22,-11,-16; D=-1;
/I:         I=-1; DM=-2;
/M: SY='D';  M= -7,  8,-28, 11, 11,-29,-12, -7,-23,  2,-28,-19,  5,-10,  5, -5,  6, -4,-20,-35,-22,  8; D=-1;
/I:         I=-1; DM=-2;
/M: SY='S';  M= -1, -9,-18,-12, -6,-17,-10, -5,-16, -4,-18,-12, -4,-14, -4, -5,  2, -1,-12,-26,-12, -6; D=-1;
/I:         I=-1; DM=-2;
/M: SY='L';  M=-12,-33,-10,-33,-26, -3,-32,-27, 17,-25, 25, 13,-33,-24,-18,-21,-22, -7, 12,-22,-11,-25; D=-1;
/I:         I=-1; DM=-2;
/M: SY='Q';  M= -6, -4,-26, -4,  4,-27,-13, -5,-24,  2,-24,-18, -3,  4,  5, -2,  1, -4,-19,-30,-19,  3; D=-1;
/I:         I=-1; DM=-2;
/M: SY='N';  M= -8,  3,-24, -1,  4,-22,-14, -3,-22,  5,-24,-15,  8,-16,  3,  0,  4, -4,-20,-27,-15,  3; D=-1;
/I:         I=-1; DM=-2;
/M: SY='I';  M= -6,-26,-11,-26,-25, -5,-30,-25, 24,-23, 11,  6,-26,-22,-21,-25,-17, -6, 23,-22, -9,-22; D=-1;
/I:         I=-1; DM=-2;
/M: SY='T';  M= -3, -6,-19, -8, -3,-21,-15,-10,-17,  1,-18,-13, -3,-10, -1,  0,  2,  3,-13,-27,-17, -3; D=-1;
/I:         I=-1; DM=-2;
/M: SY='H';  M=-13, -4,-26, -7, -1,-12,-18,  7,-21,  0,-21,-16,  1,-17, -1,  1, -4, -6,-19,-20,  3, -2; D=-1;
/I:         I=-1; DM=-2;
/M: SY='K';  M= -7, -5,-25, -9,  0,-24,-12, -9,-24,  9,-26,-19, -3,  3, -2, -3,  0, -7,-18,-29,-17,  0; D=-1;
/I:         I=-1; DM=-2;
/M: SY='G';  M= -4,  0,-28,  1, -5,-28, 24,-10,-31,-11,-34,-23,  1,-16, -8,-13,  2,-12,-25,-31,-24, -7; D=-1;
/I:         I=-1; DM=-2;
/M: SY='S';  M= -2, -2,-21, -3,  2,-23,-10, -9,-20,  3,-22,-14,  2,-12,  4, -3,  8,  1,-16,-29,-19,  2; D=-1;
/I:         I=-1; DM=-2;
/M: SY='S';  M=  0, -8,-15, -9,  0,-20,-17,-11,-12,  0,-17,-10, -4,-14,  0, -6,  2,  2, -7,-27,-15,  0; D=-1;
/I:         I=-1; DM=-2;
/M: SY='T';  M= -3, -9,-19,-10, -8,-19,-15,-15,-10, -7,-14,-10, -4,-11, -8, -8, -1,  8, -5,-29,-17, -8; D=-1;
/I:         I=-1; DM=-2;
/M:         M= -9,-13,-20,-15, -7,-13,-21,-14, -7, -7, -6, -4,-10,-16, -5, -9, -7, -4, -6,-24,-13, -7; D=-1;
/I:         I=-1; DM=-2;
/M: SY='V';  M= -8,-19,-17,-19,-17,-12,-22,-21,  4,-16,  0,  0,-18,-17,-13,-18,-11, -3,  5,-26,-14,-15;
/M: SY='S';  M= -3, -2,-25, -3,  1,-28, -3,-12,-24, -1,-28,-18,  0, -4, -2, -8,  4, -3,-18,-33,-23,  0;
/I:         I=-2; MD=-3;
/M: SY='P';  M= -3, -9,-23,-10, -5,-28, -5,-13,-23, -6,-25,-17, -7,  8, -4, -9,  0, -5,-17,-32,-23, -6; D=-2;
/I:         I=-2; MI=0; MD=-3; IM=0; DM=-3;
/M: SY='F';  M=-15,-31,-13,-35,-28, 19,-33,-21, 12,-27, 15,  9,-30,-30,-23,-25,-20,-10,  5,-10,  3,-27; D=-2;
/I:         I=-2; DM=-3;
/M: SY='N';  M= -8,  9,-25,  7,  1,-27,-12, -5,-23, -2,-30,-20, 14, -7, -1, -8,  8,  2,-20,-36,-20,  0;
/M: SY='L';  M=-14,-31,-16,-31,-24, -9,-32,-26,  7,-23, 12,  4,-30,  1,-18,-22,-21, -8,  5,-25,-14,-23;
/M: SY='S';  M= -5,  0,-26, -2,  1,-25, -6, -9,-23,  0,-25,-18,  2,-17,  0,  2,  4, -4,-20,-29,-20, -1;
/M: SY='S';  M= -4,  2,-19,  4,  3,-24, -7, -6,-22, -5,-26,-15,  3,-16,  1,-10,  7, -3,-20,-30,-18,  1;
/I:         I=-14; MD=-29;
/M: SY='L';  M=-16,-35,-11,-36,-27,  0,-36,-25, 17,-27, 30, 16,-34,-28,-19,-20,-25, -9,  9,-19, -8,-27; D=-14;
/I:         I=-14; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='L';  M=-15,-34,-13,-35,-27,  5,-35,-25, 16,-26, 24, 16,-33,-30,-19,-21,-24,-11,  9,-15, -5,-26;
/I:         I=-8; MD=-17;
/M: SY='P';  M= -7,-16,-27,-17, -7,-32,-15,-14,-26, -8,-26,-22,-16, 49, -4,-14, -7,-10,-18,-34,-24, -7; D=-8;
/I:         I=-8; MD=-17;
/M: SY='Q';  M= -4,  0,-17,  0,  2,-17, -5, -6,-16,  0,-17,-11,  0, -5,  3, -5,  3, -4,-14,-21,-14,  2; D=-8;
/I:         I=-8; MI=0; MD=-17; IM=0; DM=-17;
/M: SY='B';  M= -9,  8,-28,  8,  6,-22, -9, -6,-25,  3,-29,-20,  5,-17,  0, -3,  4, -7,-23,-31,-17,  3; D=-8;
/I:         I=-8; DM=-17;
/M: SY='T';  M= -4,-13,-15,-15,-11,-17,-18,-16, -9, -9, -8, -7, -9,-18, -8, -6, -1,  5, -7,-26,-16,-11;
/M: SY='R';  M= -9, -5,-26, -6,  0,-21,-15, -7,-19, -1,-18,-13, -3,-15,  0,  1, -2, -5,-18,-27,-15, -1;
/M: SY='E';  M= -8,  6,-28,  5,  7,-27,-11,  1,-26,  5,-29,-20,  5,-13,  5,  1,  4, -4,-22,-33,-18,  5;
/M: SY='Y';  M=-20,-30,-20,-32,-23, 37,-30, 10, -6,-23, -7, -7,-23,-32,-23,-23,-19,-19, -9, 16, 56,-23;
/M: SY='Y';  M=-16,-30,-18,-33,-23, 25,-27, -1, -4,-23, -6, -4,-25,-31,-20,-23,-19,-18, -7, 15, 36,-22;
/M: SY='R';  M= -3,-12,-22,-15, -6,-21,-16,-10,-17,  0,-14,-12, -3,-16, -2, 14,  1, 11,-14,-28,-17, -6;
/M: SY='Y';  M=-20,-29,-20,-30,-20, 30,-30, 19,-10,-19,-10,-10,-20,-30,-20,-20,-20,-20,-10, 19, 67,-20;
/M: SY='E';  M= -9,  1,-27,  2,  7,-22,-16, -4,-20, -2,-23,-15,  0,-13,  2, -6,  1, -6,-19,-28,-15,  4;
/M: SY='G';  M=  1,-10,-29,-10,-20,-30, 59,-20,-39,-20,-40,-30,-10,-20,-20,-20,  0,-20,-29,-30,-30,-20;
/M: SY='S';  M=  9, -1, -9, -1, -1,-20,  0,-11,-20, -1,-29,-20,  8, -9, -1,-11, 37, 10,-20,-30,-20, -1;
/M: SY='L';  M=-18,-35,-12,-35,-25,  0,-35,-26, 13,-26, 29, 15,-34,-28,-17,-19,-24, -7,  6,-19, -8,-25;
/M: SY='T';  M= -1, -9,-11, -9, -9,-21,-20,-19,-11, -9,-11,-11,  0, -9, -9, -9,  9, 47, -1,-31,-20, -9;
/M: SY='T';  M= -1,-10,-12,-11,-10,-17,-19,-16, -9,-10,-11, -8, -1,-13, -9,-11,  8, 36, -2,-28,-16,-10;
/M: SY='P';  M=-10,-19,-30,-19, -9,-39,-17,-20,-30,-10,-30,-30,-19, 75,-10,-20, -9,-10,-21,-39,-30, -9;
/M: SY='P';  M= -7,-14,-28,-13, -9,-36, -9,-18,-29,-11,-30,-27,-14, 50, -9,-18, -5, -8,-20,-38,-28, -9;
/I:         I=-10; MI=0; MD=-21; IM=0; DM=-21;
/M: SY='C';  M= -1,-30, 79,-39,-38,-18,-30,-29, -8,-29, -8,-17,-30,-29,-28,-38,-11,-10, -8,-20,-18,-38;
/M: SY='S';  M=  1, -3,-16, -5, -2,-17,-11, -4,-17, -5,-23,-15,  5,-15, -3, -9, 13,  6,-15,-25,-11, -3;
/M: SY='E';  M=-10,  6,-38, 14, 42,-30,-20, -1,-29,  8,-27,-18, -2, -7, 20,  0, -1, -9,-27,-30,-20, 34;
/M: SY='S';  M=  5, -8,-13,-10,-11,-23,  0,-15,-16,-11,-22,-16, -3,-12,-10,-14,  7,  4,-10,-31,-21,-10;
/M: SY='V';  M=  0,-29,-10,-29,-28,-10,-29,-29, 27,-20, 10,  9,-28,-20,-20,-28,-18,  1, 35,-29,-11,-20;
/M: SY='T';  M= -7,-17,-17,-17,-11,-15,-26,-17,  1,-11,  0, -1,-15,-17, -6,-10, -7,  6,  3,-26,-15,-10;
/M: SY='W';  M=-29,-39,-20,-49,-30,  9,-28,-20,-20,-30,-20,-20,-39,-40,-20,-30,-29,-30,-30, 98, 19,-30;
/M: SY='T';  M= -9,-19,-14,-21,-18, -5,-28,-11,  6,-18,  1, -1,-13,-22,-16,-17, -9,  9,  6,-22, -6,-18;
/M: SY='V';  M= -5,-28,-12,-27,-26, -8,-32,-28, 27,-22, 12, 10,-28,-23,-20,-28,-19, -4, 30,-27,-11,-21;
/M: SY='F';  M=-13,-26,-16,-31,-23, 24,-28,-14,  2,-23,  3,  6,-24,-31,-18,-22,-15,-13, -4, -7,  9,-23;
/M: SY='K';  M= -9, -2,-28, -7,  2,-27,-16, -9,-23, 11,-23,-16,  3,-11,  3,  9, -1, -1,-18,-32,-21,  1;
/M: SY='E';  M= -9,  4,-27,  4, 16,-27,-17, -4,-25,  9,-26,-16,  5,-13, 13,  1,  3,  0,-20,-29,-19, 14;
/M: SY='P';  M= -6,-17,-23,-18,-10,-30,-20,-17,-18, -8,-20,-19,-14, 37, -8,-14, -5,  0,-11,-34,-23, -9;
/I:         I=-10; MI=0; MD=-22; IM=0; DM=-22;
/M: SY='I';  M= -7,-25,-15,-26,-21, -8,-28,-23, 16,-17,  9,  6,-23,-24,-16,-15,-15, -7, 14,-24,-12,-19; D=-10;
/I:         I=-10; DM=-22;
/M: SY='P';  M= -4,-10,-21,-11, -3,-22,-17,-10,-18, -1,-20,-15, -8,  4, -2, -7,  0,  3,-12,-28,-15, -3; D=-10;
/I:         I=-10; DM=-22;
/M: SY='I';  M= -7,-31,-10,-31,-29, -3,-35,-29, 31,-25, 18, 14,-30,-26,-23,-27,-20, -6, 29,-23,-10,-25; D=-10;
/I:         I=-10; DM=-22;
/M: SY='S';  M=  6, -1,-12, -1, -2,-21, -4,-11,-19, -3,-26,-19,  6, -8, -2,-11, 29, 15,-16,-30,-20, -2; D=-10;
/I:         I=-10; DM=-22;
/M: SY='K';  M= -7, -7,-23,-10, -1,-19,-18, -5,-17,  2,-19,-13, -4,-11,  2,  0, -1, -5,-15,-25,-13, -1; D=-10;
/I:         I=-10; DM=-22;
/M: SY='E';  M= -6,  2,-28,  3, 10,-22,-14, -3,-22,  2,-25,-15,  0,-16,  6, -1,  1, -7,-20,-29,-15,  8;
/M: SY='Q';  M=-10, -1,-28, -1, 14,-28,-20,  5,-25,  5,-17, -1, -2,-12, 46,  5, -2, -9,-17,-22,-19, 22;
/M: SY='L';  M=-13,-35,-12,-35,-28,  1,-35,-27, 20,-26, 24, 20,-33,-29,-19,-23,-24, -9, 15,-16, -7,-26;
/M: SY='E';  M= -7, -3,-25, -4,  2,-18,-16, -3,-17, -4,-19,-12, -2,-17,  1, -6, -3, -8,-16,-28,-14,  1;
/M: SY='A';  M=  2,-13,-19,-13, -1,-20,-17,-11,-12, -1,-12, -5,-11,-16,  2, -1, -3, -3, -8,-27,-17, -1;
/M: SY='F';  M=-19,-33,-16,-38,-28, 28,-32,-18,  6,-28, 14,  9,-32,-33,-23,-25,-22,-15, -2, -2, 10,-28;
/M: SY='R';  M= -9, -7,-30,-12,  3,-24,-18, -1,-26,  9,-22,-16, -1,-16, 10, 22, -3, -8,-24,-22,-14,  3;
/M: SY='E';  M= -5,  1,-25, -1,  6,-25,-15, -3,-21,  0,-22,-14,  6,-14,  6,  1,  3, -1,-18,-31,-19,  5;
/I:         I=-7; MD=-14;
/M: SY='L';  M= -3,-27, -9,-28,-21, -8,-26,-24,  9,-19, 11,  8,-25,-19,-14,-18,-12, -3,  8,-24,-13,-20; D=-7;
/I:         I=-7; MD=-14;
/M: SY='L';  M=-10,-20,-18,-22,-13,-10,-26,-14,  0,-12,  3,  2,-17,-19, -8, -8,-12, -5, -1,-23, -9,-12; D=-7;
/I:         I=-7; MD=-14;
/M:         M= -6, -4,-21, -4, -4,-14, -6, -4,-19, -8,-20,-11, -3,-16, -1,-10, -1, -7,-16,-21, -9, -4; D=-7;
/I:         I=-7; MD=-14;
/M:         M= -7, -5,-19, -7, -5,-13,-13, -8,-15, -6,-17,-12, -2,-12, -5, -8,  0,  0,-13,-23,-10, -6; D=-7;
/I:         I=-7; MD=-14;
/M: SY='E';  M= -4, -2,-21, -2,  2,-21, -9, -8,-17, -1,-18,-12, -1,-10,  2, -3,  0, -2,-13,-26,-17,  1; D=-7;
/I:         I=-7; MD=-14;
/M: SY='E';  M= -5,  0,-18,  0,  4,-16,-10, -1,-15, -2,-15,-10,  1, -4,  2, -3,  1, -1,-12,-20,-11,  2; D=-7;
/I:         I=-7; MD=-14;
/M: SY='S';  M= -3, -2,-13, -3, -2,-15, -1, -4,-15, -2,-16,-11, -1, -3, -1, -2,  1, -3,-12,-18,-12, -2; D=-7;
/I:         I=-7; MD=-14;
/M: SY='E';  M= -2,  0,-13,  1,  2,-12, -4, -4,-10, -4,-12, -7, -1, -7,  1, -6,  0, -2, -8,-16,-10,  2; D=-7;
/I:         I=-7; MI=0; MD=-14; IM=0; DM=-14;
/M: SY='N';  M=-10,  2,-27,  1, -2,-28, -8, -7,-24, -3,-28,-20,  4, -5, -3, -7, -1, -7,-20,-34,-21, -3;
/M:         M= -5, -4,-23, -4, -2,-22, -9,-10,-18, -4,-21,-15, -5,-15, -2, -6, -1, -7,-15,-28,-18, -3;
/M:         M= -3,-13,-15,-16, -9,-21,-13,-11,-18, -7,-19,-16, -9,  0, -7, -8, -2, -5,-14,-28,-15, -9;
/M: SY='M';  M=-12,-25,-17,-27,-20, -3,-28,-17,  6,-19,  9, 12,-21,-22,-12,-18,-16, -8,  4,-20, -4,-19;
/M: SY='V';  M= -2,-15,-15,-17,-11,-15,-19,-12, -4, -9, -9, -5,-13,-17, -6,-12, -6, -2,  1,-25,-12, -9;
/M: SY='N';  M=-13, 10,-30,  7,  2,-28, -8, -3,-26,  0,-30,-20, 14,-13,  1, -4,  2, -4,-23,-35,-20,  1;
/M: SY='N';  M=-13, 17,-26,  5, -2,-28,-10,  0,-25, -3,-33,-18, 37,-14, -3, -5,  8,  3,-22,-37,-21, -2;
/M: SY='Y';  M=-10,-21,-19,-26,-19, 16,-19, -4, -7,-18,-10, -7,-16,-27,-17,-18,-10,-12, -8, -4, 18,-18;
/M: SY='R';  M=-10,-11,-38,-19, -2,-28,-20, -1,-27, 15,-18,-17, -2,-21,  8, 51,-11,-10,-27,-30,-19, -2;
/M: SY='P';  M= -6,-16,-26,-16, -5,-32,-18,-14,-24, -7,-25,-22,-15, 44, -6,-15, -5, -6,-16,-35,-24, -6;
/M: SY='V';  M= -7,-25,-13,-25,-19,-14,-29,-22,  6,-17,  5,  1,-23, -9,-12,-17,-14,  0,  9,-27,-15,-16;
/I:         I=-4; MI=0; MD=-8; IM=0; DM=-8;
/M: SY='Q';  M= -9, -2,-28, -3, 15,-27,-20, 10,-27,  8,-19, -1, -2,-11, 48,  8, -1,-10,-18,-21,-17, 23; D=-4;
/I:         I=-4; DM=-8;
/M: SY='P';  M= -6,-11,-25,-13, -6,-31,-15,-14,-25, -6,-27,-23, -9, 38, -6,-13, -1, -6,-19,-35,-24, -7; D=-4;
/I:         I=-4; DM=-8;
/M: SY='L';  M=-11,-26,-14,-26,-19, -8,-27,-23,  8,-21, 16,  8,-26,-22,-13,-17,-17, -7,  4,-23,-13,-19; D=-4;
/I:         I=-4; DM=-8;
/M: SY='N';  M=-12, 10,-27,  0, -3,-24, -1,  2,-27, -3,-32,-19, 24,-19, -4, -5,  4, -6,-25,-32,-17, -4; D=-4;
/I:         I=-4; DM=-8;
/M: SY='N';  M= -9,  8,-30,  6, -1,-27,  9, -3,-31, -6,-35,-23, 12,-18, -3, -8,  3, -9,-26,-33,-20, -2;
/M: SY='R';  M= -8,-11,-37,-20, -3,-29,-15, -3,-27, 15,-20,-19, -2,-20,  6, 48, -9,-10,-26,-30,-20, -2;
/M: SY='T';  M= -4,-14,-15,-15,-10,-18,-20,-15, -9, -8,-10, -8,-11,-12, -7, -7, -5,  2, -5,-28,-16, -9;
/M: SY='V';  M= -5,-28,-12,-29,-27, -7,-30,-27, 24,-21, 12,  9,-27,-23,-19,-25,-18, -4, 26,-26,-11,-22;
/M: SY='Y';  M=-11,-16,-23,-19, -8,  0,-23,  1,-12, -6,-12,-10,-10,-23, -5, -2, -8,-10,-12,-12, 11, -7;
/M:         M=  0,-16,-15,-19,-11,-11,-15, -8,-12, -7,-14,-10,-12,-14, -8, -7, -1, -2, -9,-22, -7,-11;
/M: SY='N';  M= -3, -1,-20, -7, -5,-16,-11, -3,-18, -4,-25,-16, 11,-14, -4, -5, 11,  0,-17,-27,-11, -5;
/M: SY='F';  M=-10,-14,-20,-18,-11,  1,-20, -6,-10,-12,-13,-10,-11,-19,-10,-13, -7, -8,-11,-15,  0,-12;
/I:         E1=0; IE=-105; DE=-105;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 124 in 123 different sequences
Number of true positive hits 124 in 123 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 2
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] Alpha-carbonic anhydrase
Version [info] 4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 123 sequences 

ATCA1_ARATH (O04846), ATCA2_ARATH (F4IHR4), ATCA3_ARATH (Q9FYE3), 

ATCA4_ARATH (F4JIK2), ATCA5_ARATH (F4HUC4), ATCA6_ARATH (Q9SUB4), 
ATCA7_ARATH (Q8L817), ATCA8_ARATH (Q9FM99), BIOR_THESB  (P86277), 
CAH10_BOVIN (A0JN41), CAH10_HUMAN (Q9NS85), CAH10_MACFA (Q9N085), 
CAH10_MOUSE (P61215), CAH10_PONAB (Q5R4U0), CAH11_BOVIN (Q866X7), 
CAH11_HUMAN (O75493), CAH11_MOUSE (O70354), CAH11_PIG   (Q866X6), 
CAH11_PONAB (Q5R665), CAH11_SHEEP (Q95203), CAH12_HUMAN (O43570), 
CAH12_MOUSE (Q8CI85), CAH12_RABIT (Q9MZ30), CAH13_HUMAN (Q8N1Q1), 
CAH13_MOUSE (Q9D6N1), CAH14_HUMAN (Q9ULX7), CAH14_MOUSE (Q9WVT6), 
CAH15_MOUSE (Q99N23), CAH1_BOVIN  (Q1LZA1), CAH1_CAEEL  (Q20781), 
CAH1_CHIHA  (P83299), CAH1_CHLRE  (P20507), CAH1_GORGO  (Q7M316), 
CAH1_HORSE  (P00917), CAH1_HUMAN  (P00915), CAH1_LOTGI  (B3A0P2), 
CAH1_MACMU  (P00916), CAH1_MACNE  (P35217), CAH1_MONDO  (Q8HY33), 
CAH1_MOUSE  (P13634), CAH1_PANTR  (Q7M317), CAH1_RABIT  (P07452), 
CAH1_RAT(B0BNN3), CAH1_SHEEP  (P48282), CAH2_BOVIN  (P00921), 
CAH2_CAEEL  (Q18932), CAH2_CHICK  (P07630), CAH2_CHLRE  (P24258), 
CAH2_HUMAN  (P00918), CAH2_LOTGI  (B3A0Q6), CAH2_MOUSE  (P00920), 
CAH2_PSEHK  (Q8UWA5), CAH2_RABIT  (P00919), CAH2_RAT(P27139), 
CAH2_SHEEP  (P00922), CAH3_BOVIN  (Q3SZX4), CAH3_CAEEL  (Q27504), 
CAH3_HORSE  (P07450), CAH3_HUMAN  (P07451), CAH3_MOUSE  (P16015), 
CAH3_PIG(Q5S1S4), CAH3_RAT(P14141), CAH4_BOVIN  (Q95323), 
CAH4_HUMAN  (P22748), CAH4_MOUSE  (Q64444), CAH4_RABIT  (P48283), 
CAH4_RAT(P48284), CAH5A_HUMAN (P35218), CAH5A_MOUSE (P23589), 
CAH5A_RAT   (P43165), CAH5B_HUMAN (Q9Y2D0), CAH5B_MOUSE (Q9QZA0), 
CAH5B_RAT   (Q66HG6), CAH5_CAEEL  (Q10462), CAH6_BOVIN  (P18915), 
CAH6_CANLF  (Q865C0), CAH6_HUMAN  (P23280), CAH6_MOUSE  (P18761), 
CAH6_SHEEP  (P08060), CAH7_HUMAN  (P43166), CAH7_MOUSE  (Q9ERQ8), 
CAH8_HUMAN  (P35219), CAH8_MOUSE  (P28651), CAH8_RAT(Q5PPN4), 
CAH9_HUMAN  (Q16790), CAH9_MOUSE  (Q8VHB5), CAHH_MONPV  (A0A7H0DN92), 
CAHH_MONPZ  (Q8V4Y0), CAHH_RABPU  (Q6RZI9), CAHH_VACCA  (O57211), 
CAHH_VACCC  (P20508), CAHH_VACCT  (Q9JFA1), CAHH_VACCW  (P04195), 
CAHH_VAR67  (P0DSY1), CAHH_VARV   (P0DSY2), CAHZ_DANRE  (Q92051), 
CAH_ACRMI   (B8V7P3), CAH_DUNSA   (P54212), CAH_KLEPN   (O52535), 
CAH_NEIGO   (Q50940), CAH_NOSS1   (P94170), CAH_PECAS   (Q6DAJ6), 
CAH_PECCA   (O52538), DB3L_DIOPO  (Q75N35), DB3S_DIOPO  (Q75N34), 
DIOA3_DIOJA (A7MAQ2), MA66_PINMA  (Q9NL38), MAC1_CRANI  (A0ZSF6), 
MAC2_CRANI  (A0ZSF7), MAF_PINFU   (A0ZSF2), MAM_PINMA   (A0ZSF3), 
MANA_PINFU  (Q27908), MANL_MYTCA  (P86856), MAP1_MIZYE  (A0ZSF4), 
MAP2_MIZYE  (A0ZSF5), NEC1_NESMA  (P0DO50), NEC3_NICLS  (Q84UV8), 
PTPRG_CHICK (Q98936), PTPRG_HUMAN (P23470), PTPRG_MOUSE (Q05909), 
PTPRZ_HUMAN (P23471), PTPRZ_MOUSE (B9EKR1), PTPRZ_RAT   (Q62656)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

CAH_LOBCS   (P84537)


				
	

	

		PDB
[Detailed view]		
		
			1331 PDB
			


			pdb_000012ca; pdb_00001a42; pdb_00001am6; pdb_00001avn; pdb_00001azm; pdb_00001bcd; pdb_00001bic; pdb_00001bn1; pdb_00001bn3; pdb_00001bn4; pdb_00001bnm; pdb_00001bnn; 
			
				pdb_00001bnq; pdb_00001bnt; pdb_00001bnu; pdb_00001bnv; pdb_00001bnw; pdb_00001bv3; pdb_00001bzm; pdb_00001ca2; pdb_00001ca3; pdb_00001cah; pdb_00001cai; pdb_00001caj; 
				pdb_00001cak; pdb_00001cal; pdb_00001cam; pdb_00001can; pdb_00001cao; pdb_00001cay; pdb_00001caz; pdb_00001ccs; pdb_00001cct; pdb_00001ccu; pdb_00001cil; pdb_00001cim; 
				pdb_00001cin; pdb_00001cnb; pdb_00001cnc; pdb_00001cng; pdb_00001cnh; pdb_00001cni; pdb_00001cnj; pdb_00001cnk; pdb_00001cnw; pdb_00001cnx; pdb_00001cny; pdb_00001cra; 
				pdb_00001crm; pdb_00001cva; pdb_00001cvb; pdb_00001cvc; pdb_00001cvd; pdb_00001cve; pdb_00001cvf; pdb_00001cvh; pdb_00001czm; pdb_00001dca; pdb_00001dcb; pdb_00001dmx; 
				pdb_00001dmy; pdb_00001eou; pdb_00001f2w; pdb_00001flj; pdb_00001fql; pdb_00001fqm; pdb_00001fqn; pdb_00001fqr; pdb_00001fr4; pdb_00001fr7; pdb_00001fsn; pdb_00001fsq; 
				pdb_00001fsr; pdb_00001g0e; pdb_00001g0f; pdb_00001g1d; pdb_00001g3z; pdb_00001g45; pdb_00001g46; pdb_00001g48; pdb_00001g4j; pdb_00001g4o; pdb_00001g52; pdb_00001g53; 
				pdb_00001g54; pdb_00001g6v; pdb_00001h4n; pdb_00001h9n; pdb_00001h9q; pdb_00001hca; pdb_00001hcb; pdb_00001hea; pdb_00001heb; pdb_00001hec; pdb_00001hed; pdb_00001hug; 
				pdb_00001huh; pdb_00001hva; pdb_00001i8z; pdb_00001i90; pdb_00001i91; pdb_00001i9l; pdb_00001i9m; pdb_00001i9n; pdb_00001i9o; pdb_00001i9p; pdb_00001i9q; pdb_00001if4; 
				pdb_00001if5; pdb_00001if6; pdb_00001if7; pdb_00001if8; pdb_00001if9; pdb_00001j9w; pdb_00001jcz; pdb_00001jd0; pdb_00001jv0; pdb_00001keq; pdb_00001kop; pdb_00001koq; 
				pdb_00001kwq; pdb_00001kwr; pdb_00001lg5; pdb_00001lg6; pdb_00001lgd; pdb_00001lug; pdb_00001lzv; pdb_00001moo; pdb_00001mua; pdb_00001okl; pdb_00001okm; pdb_00001okn; 
				pdb_00001oq5; pdb_00001ray; pdb_00001raz; pdb_00001rj5; pdb_00001rj6; pdb_00001rza; pdb_00001rzb; pdb_00001rzc; pdb_00001rzd; pdb_00001rze; pdb_00001t9n; pdb_00001tb0; 
				pdb_00001tbt; pdb_00001te3; pdb_00001teq; pdb_00001teu; pdb_00001tg3; pdb_00001tg9; pdb_00001th9; pdb_00001thk; pdb_00001ttm; pdb_00001uga; pdb_00001ugb; pdb_00001ugc; 
				pdb_00001ugd; pdb_00001uge; pdb_00001ugf; pdb_00001ugg; pdb_00001urt; pdb_00001v9e; pdb_00001v9i; pdb_00001xeg; pdb_00001xev; pdb_00001xpz; pdb_00001xq0; pdb_00001yda; 
				pdb_00001ydb; pdb_00001ydc; pdb_00001ydd; pdb_00001yo0; pdb_00001yo1; pdb_00001yo2; pdb_00001z93; pdb_00001z97; pdb_00001z9y; pdb_00001ze8; pdb_00001zfk; pdb_00001zfq; 
				pdb_00001zge; pdb_00001zgf; pdb_00001zh9; pdb_00001znc; pdb_00001zsa; pdb_00001zsb; pdb_00001zsc; pdb_00002abe; pdb_00002aw1; pdb_00002ax2; pdb_00002ca2; pdb_00002cab; 
				pdb_00002cba; pdb_00002cbb; pdb_00002cbc; pdb_00002cbd; pdb_00002cbe; pdb_00002eu2; pdb_00002eu3; pdb_00002ez7; pdb_00002f14; pdb_00002fmg; pdb_00002fmz; pdb_00002fnk; 
				pdb_00002fnm; pdb_00002fnn; pdb_00002foq; pdb_00002fos; pdb_00002fou; pdb_00002fov; pdb_00002foy; pdb_00002fw4; pdb_00002gd8; pdb_00002geh; pdb_00002h15; pdb_00002h4n; 
				pdb_00002hd6; pdb_00002hfw; pdb_00002hkk; pdb_00002hl4; pdb_00002hnc; pdb_00002hoc; pdb_00002ili; pdb_00002it4; pdb_00002nmx; pdb_00002nn1; pdb_00002nn7; pdb_00002nng; 
				pdb_00002nno; pdb_00002nns; pdb_00002nnv; pdb_00002nwo; pdb_00002nwp; pdb_00002nwy; pdb_00002nwz; pdb_00002nxr; pdb_00002nxs; pdb_00002nxt; pdb_00002o4z; pdb_00002osf; 
				pdb_00002osm; pdb_00002pou; pdb_00002pov; pdb_00002pow; pdb_00002q1b; pdb_00002q1q; pdb_00002q38; pdb_00002qo8; pdb_00002qoa; pdb_00002qp6; pdb_00002vva; pdb_00002vvb; 
				pdb_00002w2j; pdb_00002wd2; pdb_00002wd3; pdb_00002weg; pdb_00002weh; pdb_00002wej; pdb_00002weo; pdb_00002x7s; pdb_00002x7t; pdb_00002x7u; pdb_00002znc; pdb_00003b1b; 
				pdb_00003b4f; pdb_00003bet; pdb_00003bl0; pdb_00003bl1; pdb_00003c7p; pdb_00003ca2; pdb_00003caj; pdb_00003cyu; pdb_00003czv; pdb_00003d0n; pdb_00003d8w; pdb_00003d92; 
				pdb_00003d93; pdb_00003d9z; pdb_00003da2; pdb_00003daz; pdb_00003dbu; pdb_00003dc3; pdb_00003dc9; pdb_00003dcc; pdb_00003dcs; pdb_00003dcw; pdb_00003dd0; pdb_00003dd8; 
				pdb_00003dv7; pdb_00003dvb; pdb_00003dvc; pdb_00003dvd; pdb_00003efi; pdb_00003eft; pdb_00003f4x; pdb_00003f7b; pdb_00003f7u; pdb_00003f8e; pdb_00003fe4; pdb_00003ffp; 
				pdb_00003fw3; pdb_00003gz0; pdb_00003hfp; pdb_00003hkn; pdb_00003hkq; pdb_00003hkt; pdb_00003hku; pdb_00003hlj; pdb_00003hs4; pdb_00003iai; pdb_00003ibi; pdb_00003ibl; 
				pdb_00003ibn; pdb_00003ibu; pdb_00003ieo; pdb_00003igp; pdb_00003jxf; pdb_00003jxg; pdb_00003jxh; pdb_00003k2f; pdb_00003k34; pdb_00003k7k; pdb_00003kig; pdb_00003kkx; 
				pdb_00003kld; pdb_00003kne; pdb_00003koi; pdb_00003kok; pdb_00003kon; pdb_00003ks3; pdb_00003kwa; pdb_00003l14; pdb_00003lxe; pdb_00003m04; pdb_00003m14; pdb_00003m1j; 
				pdb_00003m1k; pdb_00003m1q; pdb_00003m1w; pdb_00003m2n; pdb_00003m2x; pdb_00003m2y; pdb_00003m2z; pdb_00003m3x; pdb_00003m40; pdb_00003m5e; pdb_00003m5s; pdb_00003m5t; 
				pdb_00003m67; pdb_00003m96; pdb_00003m98; pdb_00003mdz; pdb_00003mhc; pdb_00003mhi; pdb_00003mhl; pdb_00003mhm; pdb_00003mho; pdb_00003ml2; pdb_00003ml5; pdb_00003mmf; 
				pdb_00003mna; pdb_00003mnh; pdb_00003mni; pdb_00003mnj; pdb_00003mnk; pdb_00003mnu; pdb_00003mwo; pdb_00003myq; pdb_00003mzc; pdb_00003n0n; pdb_00003n2p; pdb_00003n3j; 
				pdb_00003n4b; pdb_00003nb5; pdb_00003ni5; pdb_00003nj9; pdb_00003oik; pdb_00003oil; pdb_00003oim; pdb_00003oku; pdb_00003okv; pdb_00003oy0; pdb_00003oyq; pdb_00003oys; 
				pdb_00003p3h; pdb_00003p3j; pdb_00003p44; pdb_00003p4v; pdb_00003p55; pdb_00003p58; pdb_00003p5a; pdb_00003p5l; pdb_00003pjj; pdb_00003po6; pdb_00003pyk; pdb_00003qyk; 
				pdb_00003r16; pdb_00003r17; pdb_00003rg3; pdb_00003rg4; pdb_00003rge; pdb_00003rj7; pdb_00003rld; pdb_00003ryj; pdb_00003ryv; pdb_00003ryx; pdb_00003ryy; pdb_00003ryz; 
				pdb_00003rz0; pdb_00003rz1; pdb_00003rz5; pdb_00003rz7; pdb_00003rz8; pdb_00003s71; pdb_00003s72; pdb_00003s73; pdb_00003s74; pdb_00003s75; pdb_00003s76; pdb_00003s77; 
				pdb_00003s78; pdb_00003s8x; pdb_00003s97; pdb_00003s9t; pdb_00003sap; pdb_00003sax; pdb_00003sbh; pdb_00003sbi; pdb_00003t5u; pdb_00003t5z; pdb_00003t82; pdb_00003t83; 
				pdb_00003t84; pdb_00003t85; pdb_00003tmj; pdb_00003tvn; pdb_00003tvo; pdb_00003u3a; pdb_00003u45; pdb_00003u47; pdb_00003u7c; pdb_00003uyn; pdb_00003uyq; pdb_00003v2j; 
				pdb_00003v2m; pdb_00003v3f; pdb_00003v3g; pdb_00003v3h; pdb_00003v3i; pdb_00003v3j; pdb_00003v5g; pdb_00003v7x; pdb_00003vbd; pdb_00003w6h; pdb_00003w6i; pdb_00003znc; 
				pdb_00003zp9; pdb_00004bcw; pdb_00004bf1; pdb_00004bf6; pdb_00004ca2; pdb_00004cac; pdb_00004cnr; pdb_00004cnv; pdb_00004cnw; pdb_00004cnx; pdb_00004cq0; pdb_00004dz7; 
				pdb_00004dz9; pdb_00004e3d; pdb_00004e3f; pdb_00004e3g; pdb_00004e3h; pdb_00004e49; pdb_00004e4a; pdb_00004e5q; pdb_00004fik; pdb_00004fl7; pdb_00004fpt; pdb_00004frc; 
				pdb_00004fu5; pdb_00004fvn; pdb_00004fvo; pdb_00004g0c; pdb_00004gl1; pdb_00004hba; pdb_00004hew; pdb_00004hey; pdb_00004hez; pdb_00004hf3; pdb_00004ht0; pdb_00004ht2; 
				pdb_00004hu1; pdb_00004idr; pdb_00004ilx; pdb_00004ito; pdb_00004itp; pdb_00004iwz; pdb_00004js6; pdb_00004jsa; pdb_00004jss; pdb_00004jsw; pdb_00004jsz; pdb_00004k0s; 
				pdb_00004k0t; pdb_00004k0z; pdb_00004k13; pdb_00004k1q; pdb_00004kap; pdb_00004kni; pdb_00004knj; pdb_00004knm; pdb_00004knn; pdb_00004kp5; pdb_00004kp8; pdb_00004kuv; 
				pdb_00004kuw; pdb_00004kuy; pdb_00004kv0; pdb_00004l5u; pdb_00004l5v; pdb_00004l5w; pdb_00004lhi; pdb_00004lp6; pdb_00004lu3; pdb_00004m2r; pdb_00004m2u; pdb_00004m2v; 
				pdb_00004m2w; pdb_00004mdg; pdb_00004mdl; pdb_00004mdm; pdb_00004mlt; pdb_00004mlx; pdb_00004mo8; pdb_00004mty; pdb_00004n0x; pdb_00004n16; pdb_00004pq7; pdb_00004pxx; 
				pdb_00004pyx; pdb_00004pyy; pdb_00004pzh; pdb_00004q06; pdb_00004q07; pdb_00004q08; pdb_00004q09; pdb_00004q0l; pdb_00004q49; pdb_00004q6d; pdb_00004q6e; pdb_00004q78; 
				pdb_00004q7p; pdb_00004q7s; pdb_00004q7v; pdb_00004q7w; pdb_00004q81; pdb_00004q83; pdb_00004q87; pdb_00004q8x; pdb_00004q8y; pdb_00004q8z; pdb_00004q90; pdb_00004q99; 
				pdb_00004q9y; pdb_00004qef; pdb_00004qiy; pdb_00004qiz; pdb_00004qj0; pdb_00004qjm; pdb_00004qjo; pdb_00004qjp; pdb_00004qjw; pdb_00004qjx; pdb_00004qk1; pdb_00004qk2; 
				pdb_00004qk3; pdb_00004qsa; pdb_00004qsb; pdb_00004qsi; pdb_00004qsj; pdb_00004qtl; pdb_00004qy3; pdb_00004r59; pdb_00004r5a; pdb_00004r5b; pdb_00004rfc; pdb_00004rfd; 
				pdb_00004rh2; pdb_00004riu; pdb_00004riv; pdb_00004rn4; pdb_00004rux; pdb_00004ruy; pdb_00004ruz; pdb_00004twl; pdb_00004twm; pdb_00004wl4; pdb_00004wr7; pdb_00004wup; 
				pdb_00004wuq; pdb_00004ww6; pdb_00004ww8; pdb_00004xe1; pdb_00004y0j; pdb_00004ygj; pdb_00004ygk; pdb_00004ygl; pdb_00004ygn; pdb_00004yvy; pdb_00004ywp; pdb_00004yx4; 
				pdb_00004yxi; pdb_00004yxo; pdb_00004yxu; pdb_00004yyt; pdb_00004z0q; pdb_00004z1e; pdb_00004z1j; pdb_00004z1k; pdb_00004z1n; pdb_00004zao; pdb_00004zwi; pdb_00004zwx; 
				pdb_00004zwy; pdb_00004zwz; pdb_00004zx0; pdb_00004zx1; pdb_00005a25; pdb_00005a6h; pdb_00005amd; pdb_00005amg; pdb_00005aml; pdb_00005bnl; pdb_00005bru; pdb_00005brv; 
				pdb_00005brw; pdb_00005byi; pdb_00005c8i; pdb_00005ca2; pdb_00005cac; pdb_00005cjf; pdb_00005clu; pdb_00005dog; pdb_00005doh; pdb_00005drs; pdb_00005dsk; pdb_00005dsl; 
				pdb_00005dsm; pdb_00005dso; pdb_00005dsp; pdb_00005dsq; pdb_00005dsr; pdb_00005dvx; pdb_00005e28; pdb_00005e2k; pdb_00005e2m; pdb_00005e2n; pdb_00005e2r; pdb_00005e2s; 
				pdb_00005e5r; pdb_00005e5u; pdb_00005eh5; pdb_00005eh7; pdb_00005eh8; pdb_00005ehe; pdb_00005ehv; pdb_00005ehw; pdb_00005eij; pdb_00005ekh; pdb_00005ekj; pdb_00005ekm; 
				pdb_00005eoi; pdb_00005ezt; pdb_00005fdc; pdb_00005fdi; pdb_00005fl4; pdb_00005fl5; pdb_00005fl6; pdb_00005flo; pdb_00005flp; pdb_00005flq; pdb_00005flr; pdb_00005fls; 
				pdb_00005flt; pdb_00005fng; pdb_00005fnh; pdb_00005fni; pdb_00005fnj; pdb_00005fnk; pdb_00005fnl; pdb_00005fnm; pdb_00005g01; pdb_00005g03; pdb_00005g0b; pdb_00005g0c; 
				pdb_00005gmm; pdb_00005gmn; pdb_00005ipz; pdb_00005j8z; pdb_00005jdv; pdb_00005je7; pdb_00005jeg; pdb_00005jeh; pdb_00005jep; pdb_00005jes; pdb_00005jg3; pdb_00005jg5; 
				pdb_00005jgs; pdb_00005jgt; pdb_00005jmz; pdb_00005jn3; pdb_00005jn7; pdb_00005jn8; pdb_00005jn9; pdb_00005jna; pdb_00005jnc; pdb_00005jq0; pdb_00005jqt; pdb_00005ku6; 
				pdb_00005l3o; pdb_00005l6k; pdb_00005l6t; pdb_00005l70; pdb_00005l9e; pdb_00005ljq; pdb_00005ljt; pdb_00005ll4; pdb_00005ll5; pdb_00005ll8; pdb_00005ll9; pdb_00005lla; 
				pdb_00005llc; pdb_00005lle; pdb_00005llg; pdb_00005llh; pdb_00005lln; pdb_00005llo; pdb_00005llp; pdb_00005lmd; pdb_00005lvs; pdb_00005m78; pdb_00005mjn; pdb_00005msa; 
				pdb_00005msb; pdb_00005n0d; pdb_00005n0e; pdb_00005n1r; pdb_00005n1s; pdb_00005n24; pdb_00005n25; pdb_00005nea; pdb_00005nee; pdb_00005nxg; pdb_00005nxi; pdb_00005nxm; 
				pdb_00005nxo; pdb_00005nxp; pdb_00005nxv; pdb_00005nxw; pdb_00005ny1; pdb_00005ny3; pdb_00005ny6; pdb_00005nya; pdb_00005o07; pdb_00005ogj; pdb_00005ogn; pdb_00005ogo; 
				pdb_00005ogp; pdb_00005ohh; pdb_00005sz0; pdb_00005sz1; pdb_00005sz2; pdb_00005sz3; pdb_00005sz4; pdb_00005sz5; pdb_00005sz6; pdb_00005sz7; pdb_00005t71; pdb_00005t72; 
				pdb_00005t74; pdb_00005t75; pdb_00005tfx; pdb_00005th4; pdb_00005thi; pdb_00005thj; pdb_00005thn; pdb_00005ti0; pdb_00005txy; pdb_00005ty1; pdb_00005ty8; pdb_00005ty9; 
				pdb_00005tya; pdb_00005u0d; pdb_00005u0e; pdb_00005u0f; pdb_00005u0g; pdb_00005uln; pdb_00005umc; pdb_00005vgy; pdb_00005w8b; pdb_00005wex; pdb_00005wg7; pdb_00005wgp; 
				pdb_00005wlr; pdb_00005wlt; pdb_00005wlu; pdb_00005wlv; pdb_00005y2r; pdb_00005y2s; pdb_00005yui; pdb_00005yuj; pdb_00005yuk; pdb_00005zxw; pdb_00006b4d; pdb_00006b59; 
				pdb_00006b5a; pdb_00006bbs; pdb_00006bc9; pdb_00006bcc; pdb_00006c7w; pdb_00006c7x; pdb_00006ca2; pdb_00006ceh; pdb_00006cjv; pdb_00006d1l; pdb_00006d1m; pdb_00006e8p; 
				pdb_00006e8x; pdb_00006e91; pdb_00006e92; pdb_00006ebe; pdb_00006ecz; pdb_00006eda; pdb_00006eea; pdb_00006eeh; pdb_00006eeo; pdb_00006equ; pdb_00006evr; pdb_00006ex1; 
				pdb_00006f3b; pdb_00006faf; pdb_00006fag; pdb_00006fe0; pdb_00006fe1; pdb_00006fe2; pdb_00006fji; pdb_00006fjj; pdb_00006g3q; pdb_00006g3v; pdb_00006g4t; pdb_00006g5l; 
				pdb_00006g5u; pdb_00006g6t; pdb_00006g7a; pdb_00006g98; pdb_00006g9u; pdb_00006gcy; pdb_00006gdc; pdb_00006gm9; pdb_00006got; pdb_00006gxb; pdb_00006gxe; pdb_00006h29; 
				pdb_00006h2z; pdb_00006h33; pdb_00006h34; pdb_00006h36; pdb_00006h37; pdb_00006h38; pdb_00006h3q; pdb_00006h6s; pdb_00006hd2; pdb_00006hqx; pdb_00006hr3; pdb_00006hwz; 
				pdb_00006hx5; pdb_00006hxd; pdb_00006hzx; pdb_00006i0j; pdb_00006i0l; pdb_00006i0w; pdb_00006i1u; pdb_00006i2f; pdb_00006i3e; pdb_00006ic2; pdb_00006klz; pdb_00006km0; 
				pdb_00006km1; pdb_00006km2; pdb_00006km3; pdb_00006km4; pdb_00006km5; pdb_00006km6; pdb_00006luu; pdb_00006luv; pdb_00006luw; pdb_00006lux; pdb_00006luy; pdb_00006luz; 
				pdb_00006lv1; pdb_00006lv2; pdb_00006lv3; pdb_00006lv4; pdb_00006lv5; pdb_00006lv6; pdb_00006lv7; pdb_00006lv8; pdb_00006lv9; pdb_00006lva; pdb_00006mbv; pdb_00006mby; 
				pdb_00006nlv; pdb_00006nm0; pdb_00006odz; pdb_00006oe0; pdb_00006oe1; pdb_00006oti; pdb_00006otk; pdb_00006otm; pdb_00006oto; pdb_00006otp; pdb_00006otq; pdb_00006oub; 
				pdb_00006oud; pdb_00006oue; pdb_00006ouf; pdb_00006ouh; pdb_00006oui; pdb_00006ouj; pdb_00006ouk; pdb_00006oum; pdb_00006pdv; pdb_00006pea; pdb_00006pgx; pdb_00006q3o; 
				pdb_00006q9t; pdb_00006qeb; pdb_00006ql1; pdb_00006ql2; pdb_00006ql3; pdb_00006qn0; pdb_00006qn2; pdb_00006qn5; pdb_00006qn6; pdb_00006qng; pdb_00006qnl; pdb_00006qut; 
				pdb_00006r6f; pdb_00006r6j; pdb_00006r6y; pdb_00006r71; pdb_00006rfh; pdb_00006rg3; pdb_00006rg4; pdb_00006rg5; pdb_00006rh4; pdb_00006rhj; pdb_00006rhk; pdb_00006rig; 
				pdb_00006rit; pdb_00006rjj; pdb_00006rkn; pdb_00006rl9; pdb_00006rm1; pdb_00006rmp; pdb_00006rmx; pdb_00006rmy; pdb_00006rnp; pdb_00006rob; pdb_00006roe; pdb_00006rof; 
				pdb_00006rps; pdb_00006rqi; pdb_00006rqn; pdb_00006rqq; pdb_00006rqu; pdb_00006rqw; pdb_00006rrg; pdb_00006rri; pdb_00006rs5; pdb_00006rsz; pdb_00006rvf; pdb_00006rvk; 
				pdb_00006rvl; pdb_00006rw1; pdb_00006rzx; pdb_00006s03; pdb_00006s9g; pdb_00006s9z; pdb_00006sac; pdb_00006sas; pdb_00006say; pdb_00006sb7; pdb_00006sbh; pdb_00006sbl; 
				pdb_00006sbm; pdb_00006sd7; pdb_00006sdh; pdb_00006sdi; pdb_00006sdj; pdb_00006sdl; pdb_00006sds; pdb_00006sdt; pdb_00006sey; pdb_00006sfq; pdb_00006sfu; pdb_00006sg0; 
				pdb_00006sg6; pdb_00006sks; pdb_00006skt; pdb_00006skv; pdb_00006swm; pdb_00006sx9; pdb_00006syb; pdb_00006sys; pdb_00006t4n; pdb_00006t4o; pdb_00006t4p; pdb_00006t5c; 
				pdb_00006t5p; pdb_00006t5q; pdb_00006t7u; pdb_00006t81; pdb_00006t9z; pdb_00006tl5; pdb_00006tl6; pdb_00006u4q; pdb_00006u4t; pdb_00006ufb; pdb_00006ufc; pdb_00006ufd; 
				pdb_00006ugn; pdb_00006ugo; pdb_00006ugp; pdb_00006ugq; pdb_00006ugr; pdb_00006ugz; pdb_00006uh0; pdb_00006ux1; pdb_00006uzu; pdb_00006vj3; pdb_00006vkg; pdb_00006wka; 
				pdb_00006wq4; pdb_00006wq5; pdb_00006wq7; pdb_00006wq8; pdb_00006wq9; pdb_00006xvh; pdb_00006xwz; pdb_00006xxt; pdb_00006xze; pdb_00006xzo; pdb_00006xzs; pdb_00006xzx; 
				pdb_00006xzy; pdb_00006y00; pdb_00006y74; pdb_00006yh4; pdb_00006yh5; pdb_00006yh6; pdb_00006yh7; pdb_00006yh8; pdb_00006yh9; pdb_00006yha; pdb_00006yhb; pdb_00006yhc; 
				pdb_00006yj3; pdb_00006ykc; pdb_00006ykh; pdb_00006yma; pdb_00006ymb; pdb_00006yo2; pdb_00006yo4; pdb_00006yo7; pdb_00006yoi; pdb_00006yok; pdb_00006yol; pdb_00006ypw; 
				pdb_00006yqt; pdb_00006yqu; pdb_00006yri; pdb_00006yzj; pdb_00006yzk; pdb_00006yzl; pdb_00006yzm; pdb_00006yzn; pdb_00006yzo; pdb_00006yzp; pdb_00006yzq; pdb_00006yzr; 
				pdb_00006yzs; pdb_00006yzt; pdb_00006yzu; pdb_00006yzv; pdb_00006yzw; pdb_00006yzx; pdb_00006z04; pdb_00006zr8; pdb_00006zr9; pdb_00007a6v; pdb_00007aeq; pdb_00007aes; 
				pdb_00007agn; pdb_00007asj; pdb_00007bfa; pdb_00007bg5; pdb_00007bhh; pdb_00007bi5; pdb_00007ca2; pdb_00007jnr; pdb_00007jnv; pdb_00007jnw; pdb_00007jnx; pdb_00007jnz; 
				pdb_00007jo0; pdb_00007jo1; pdb_00007jo2; pdb_00007jo3; pdb_00007job; pdb_00007joc; pdb_00007k6i; pdb_00007k6j; pdb_00007k6k; pdb_00007k6l; pdb_00007k6t; pdb_00007k6u; 
				pdb_00007k6x; pdb_00007k6z; pdb_00007m23; pdb_00007m24; pdb_00007m26; pdb_00007mu3; pdb_00007nc4; pdb_00007nh6; pdb_00007nh8; pdb_00007ntb; pdb_00007nzr; pdb_00007nzs; 
				pdb_00007nzt; pdb_00007nzu; pdb_00007nzw; pdb_00007nzx; pdb_00007ok8; pdb_00007onv; pdb_00007orp; pdb_00007orq; pdb_00007oym; pdb_00007oyn; pdb_00007oyo; pdb_00007oyp; 
				pdb_00007oyq; pdb_00007oyr; pdb_00007p1a; pdb_00007plf; pdb_00007pom; pdb_00007pp9; pdb_00007puu; pdb_00007puv; pdb_00007puw; pdb_00007q0c; pdb_00007q0d; pdb_00007q0e; 
				pdb_00007qbh; pdb_00007qgx; pdb_00007qgy; pdb_00007qgz; pdb_00007qnv; pdb_00007qob; pdb_00007qrk; pdb_00007qse; pdb_00007qsi; pdb_00007qzx; pdb_00007r1x; pdb_00007rny; 
				pdb_00007rnz; pdb_00007rre; pdb_00007rrf; pdb_00007suw; pdb_00007suy; pdb_00007sv1; pdb_00007sv8; pdb_00007u5w; pdb_00007u5x; pdb_00007y2a; pdb_00007y2c; pdb_00007y2e; 
				pdb_00007y2f; pdb_00007y2g; pdb_00007y2h; pdb_00007y2i; pdb_00007y2j; pdb_00007y2k; pdb_00007y2l; pdb_00007y2m; pdb_00007y2n; pdb_00007y2o; pdb_00007y2q; pdb_00007y2r; 
				pdb_00007y2s; pdb_00007y2t; pdb_00007y2u; pdb_00007y2v; pdb_00007y2w; pdb_00007y2x; pdb_00007ywt; pdb_00007zl5; pdb_00007zl6; pdb_00007zwb; pdb_00008aa6; pdb_00008aae; 
				pdb_00008b29; pdb_00008bjx; pdb_00008boe; pdb_00008bzz; pdb_00008c0q; pdb_00008c0r; pdb_00008ca2; pdb_00008cdx; pdb_00008cdz; pdb_00008co0; pdb_00008co3; pdb_00008cr0; 
				pdb_00008dj9; pdb_00008dpc; pdb_00008dpo; pdb_00008dqf; pdb_00008dr2; pdb_00008drb; pdb_00008dyq; pdb_00008em3; pdb_00008emu; pdb_00008exc; pdb_00008exg; pdb_00008eyl; 
				pdb_00008fal; pdb_00008fau; pdb_00008fqx; pdb_00008fqy; pdb_00008fqz; pdb_00008fr1; pdb_00008fr2; pdb_00008fr4; pdb_00008igf; pdb_00008j2o; pdb_00008jee; pdb_00008jif; 
				pdb_00008ogd; pdb_00008oge; pdb_00008ogf; pdb_00008oke; pdb_00008okg; pdb_00008okj; pdb_00008oko; pdb_00008okp; pdb_00008okq; pdb_00008okt; pdb_00008ola; pdb_00008olf; 
				pdb_00008oli; pdb_00008olk; pdb_00008olm; pdb_00008omb; pdb_00008omh; pdb_00008omn; pdb_00008omp; pdb_00008oo8; pdb_00008otp; pdb_00008oub; pdb_00008p6u; pdb_00008phl; 
				pdb_00008phm; pdb_00008q0c; pdb_00008q18; pdb_00008q19; pdb_00008q1a; pdb_00008q3u; pdb_00008q6l; pdb_00008q7g; pdb_00008qf7; pdb_00008qf9; pdb_00008qfk; pdb_00008qgv; 
				pdb_00008qh8; pdb_00008qhg; pdb_00008qhj; pdb_00008qho; pdb_00008qkz; pdb_00008qq9; pdb_00008qqa; pdb_00008quf; pdb_00008qun; pdb_00008r1i; pdb_00008r2f; pdb_00008r2k; 
				pdb_00008rar; pdb_00008rbp; pdb_00008rj2; pdb_00008rlo; pdb_00008rlp; pdb_00008rlq; pdb_00008rns; pdb_00008rou; pdb_00008row; pdb_00008s4f; pdb_00008saf; pdb_00008sag; 
				pdb_00008sd1; pdb_00008sd6; pdb_00008sd7; pdb_00008sd8; pdb_00008sd9; pdb_00008sf1; pdb_00008ttr; pdb_00008ufw; pdb_00008ufx; pdb_00008vzg; pdb_00008wep; pdb_00008wer; 
				pdb_00008wes; pdb_00008zwv; pdb_00009ca2; pdb_00009f15; pdb_00009f2e; pdb_00009f2f; pdb_00009g38; pdb_00009gfv; pdb_00009gfw; pdb_00009gfx; pdb_00009h3h
			
			

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