General rule information
[?]
Accession |
PRU01134 |
Dates |
19-APR-2016 (Created) 19-NOV-2022 (Last updated, Version 7) |
Predictors |
PROSITE; PS51144; ALPHA_CA_2
|
Name |
Alpha-carbonic anhydrase domain |
Propagated annotation
[?]
case <FTGroup:1> and <FTGroup:2>
end case
case <FTGroup:2>
end case
case <FTGroup:1> and <FTGroup:2>
GO:0004089; Molecular function: carbonate dehydratase activity.
end case
case <FTGroup:2> or <FTGroup:3>
GO:0046872; Molecular function: metal ion binding.
GO:0008270; Molecular function: zinc ion binding.
end case
From: PS51144 |
Key
|
|
From
|
|
To
|
|
Description
|
|
Tag
|
|
Condition
|
|
FTGroup
|
DOMAIN
|
|
from
|
|
to
|
|
Alpha-carbonic anhydrase #
|
|
|
|
|
|
|
ACT_SITE
|
|
64
|
|
64
|
|
Proton acceptor
|
|
|
|
H
|
|
1
|
BINDING
|
|
64
|
|
64
|
|
/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2
|
|
|
|
H
|
|
3
|
BINDING
|
|
67
|
|
67
|
|
/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2
|
|
|
|
H
|
|
3
|
BINDING
|
|
93
|
|
93
|
|
/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" /ligand_note="catalytic
|
|
|
|
H
|
|
2
|
BINDING
|
|
95
|
|
95
|
|
/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" /ligand_note="catalytic
|
|
|
|
H
|
|
2
|
BINDING
|
|
118
|
|
118
|
|
/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1" /ligand_note="catalytic
|
|
|
|
H
|
|
2
|
BINDING
|
|
201
|
|
201
|
|
/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2
|
|
|
|
H
|
|
3
|
Additional information
[?]
Size range |
15-523 amino acids |
Related rules |
None |
Repeats |
1-2 |
Topology |
Undefined |
Example |
P22748 (CAH4_HUMAN) |
Scope |
Eukaryota
Viruses; Orthopoxvirus
Bacteria |
Comments |
None |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and
distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives
(CC BY-NC-ND 4.0) License, see
prosite_license.html.
UniProtKB rule member sequences
[?]