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| Entry: PS51150 |
General information about the entry
| Entry name [info] | AGOUTI_2 |
| Accession [info] | PS51150 |
| Entry type [info] | MATRIX |
| Date [info] |
01-OCT-2005 CREATED;
10-MAY-2017 DATA UPDATE; 02-JUN-2021 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC60024 |
| Associated ProRule [info] | PRU00494 |
Name and characterization of the entry
| Description [info] | Agouti domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=40; /DISJOINT: DEFINITION=PROTECT; N1=5; N2=36; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.7000277; R2=0.0052378; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=2728.9633789; R2=3.2879581; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=1108; H_SCORE=6372; N_SCORE=8.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=726; H_SCORE=5116; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-11; D=-50; I=-50; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105; ... A B C D E F G H I K L M N P Q R S T V W Y Z /I: B1=0; BI=-105; BD=-105; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='V'; M= 0,-30,-10,-30,-30, 0,-30,-30, 30,-20, 10, 10,-30,-30,-30,-20,-10, 0, 50,-30,-10,-30; /M: SY='A'; M= 28,-10,-16,-17, -7,-20, -6,-14,-16, 3,-13,-10, -7,-13, -4, 8, 4, -3, -6,-20,-17, -7; /M: SY='T'; M= -4, -5,-14,-13,-12, -5,-21,-16, -2,-15, 7, -2, -2,-17,-12,-12, 3, 25, 0,-28, -8,-12; /M: SY='R'; M=-17,-16,-27,-16, -6,-11,-23, -6,-14, 11, 2, -1, -9,-23, 1, 42,-16,-10,-11,-20, -7, -6; /M: SY='D'; M=-15, 35,-28, 43, 28,-32,-11, 2,-32, 3,-27,-25, 23, -9, 6, -5, 2, -8,-30,-37,-20, 17; /M: SY='S'; M= 10, 0,-10, 0, 0,-20, 0,-10,-20,-10,-30,-20, 10,-10, 0,-10, 40, 20,-10,-40,-20, 0; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='K'; M=-10, -9,-27, -9, 1,-17,-23,-13,-14, 25, -5, -1, -9,-16, 1, 14,-16,-10,-11,-20, -7, 1; /M: SY='P'; M= -4,-14,-32, -8, -6,-28, 11,-18,-26,-13,-30,-20, -9, 40,-12,-18, 1, -9,-27,-28,-28,-12; /M: SY='P'; M=-13,-14,-37, -7, 0,-27,-20, 18,-23,-10,-27,-14,-11, 55, -4,-14,-10,-13,-30,-30,-14, -7; /M: SY='A'; M= 31, -7,-16,-14, -1,-26, -6,-11,-13, -4,-13, -7, -7,-10, 12,-11, 7, -3, -9,-20,-17, 6; /M: SY='P'; M=-10,-24,-35,-22,-12,-16,-27,-23, 7,-19, -5, -3,-21, 41,-14,-23,-15,-10, -6,-26,-17,-17; /M: SY='A'; M= 31,-13,-19,-17, -7,-23, -6,-20,-13,-10,-16,-13,-13, 22,-10,-20, 4, -3, -9,-23,-23,-10; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='D'; M=-19, 49,-29, 64, 18,-38, -9, 1,-38, 0,-30,-29, 25,-11, 0, -9, 1, -9,-30,-40,-20, 9; /M: SY='P'; M=-10,-20,-40,-10, 0,-30,-20,-20,-20,-10,-30,-20,-20, 90,-10,-20,-10,-10,-30,-30,-30,-10; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='A'; M= 50,-10,-10,-20,-10,-20, 0,-20,-10,-10,-10,-10,-10,-10,-10,-20, 10, 0, 0,-20,-20,-10; /M: SY='S'; M= 2, -5,-12,-10, -8, 0,-11,-15,-13,-13,-17,-13, 2,-13,-10,-12, 24, 24, -5,-28, -8, -8; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='Q'; M=-13, -6,-30, -6, 7,-18,-23, 13,-14, 4,-14, 0, -6,-16, 38, 4, -6,-10,-24, -4, 18, 21; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='R'; M=-20,-10,-30,-10, 0,-20,-20, 0,-30, 30,-20,-10, 0,-20, 10, 70,-10,-10,-20,-20,-10, 0; /M: SY='F'; M=-20,-30,-20,-40,-30, 80,-30,-20, 0,-30, 10, 0,-20,-30,-40,-20,-20,-10, 0, 10, 30,-30; /M: SY='F'; M=-20,-30,-20,-40,-30, 80,-30,-20, 0,-30, 10, 0,-20,-30,-40,-20,-20,-10, 0, 10, 30,-30; /M: SY='R'; M=-14, 6,-27, -1, -3,-22, 1, 0,-28, 13,-25,-15, 19,-20, 2, 33, -2, -8,-25,-26,-16, -3; /M: SY='S'; M= 23, -3,-10, -6, -3,-20, 0,-13,-17,-10,-24,-17, 4,-10, -3,-13, 31, 14, -7,-34,-20, -3; /M: SY='A'; M= 26,-16,-13,-25,-16, 12, -9,-19, -7,-16, -5, -7,-12,-16,-19,-19, 2, -2, -1,-12, -4,-16; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='T'; M= -3, -6,-16, -9, -9, -1,-16, -4,-11,-10,-14,-11, -3,-16, -6,-10, 15, 20, -7,-15, 15, -9; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='R'; M=-20,-10,-30,-10, 0,-20,-20, 0,-30, 30,-20,-10, 0,-20, 10, 70,-10,-10,-20,-20,-10, 0; /M: SY='V'; M= -3,-21,-16,-21,-17, -9,-27,-24, 11, 2, -3, 4,-21,-24,-17, -4,-10, -3, 28,-27,-10,-17; /M: SY='L'; M=-10,-30,-23,-33,-23, 7,-33,-23, 29,-30, 41, 20,-27,-27,-20,-23,-27,-10, 16,-20, 0,-23; /M: SY='N'; M= 2, 16,-14, 7, -1,-19, -1, -3,-19, -6,-29,-19, 29,-14, -1, -6, 27, 14,-17,-39,-19, -1; /M: SY='P'; M= -8,-14,-28,-11, -5,-20,-21,-19,-15, -9,-17,-13,-13, 42, -9,-11, -2, 9,-17,-29,-20,-10; /M: SY='T'; M= -3, 9,-14, -2, -6,-14,-14,-11,-15, -5,-17,-13, 15,-13, -5, -2, 17, 31, -9,-32,-13, -6; /I: I=-14; MI=0; MD=-29; IM=0; DM=-29; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /I: E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
| Total number of hits | 48 in 48 different sequences |
| Number of true positive hits | 48 in 48 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 10 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 82.76 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Feature key [info] | DOMAIN |
| Feature description [info] | Agouti |
| Version [info] | 5 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
48 sequences
AGRP_BOVIN (P56413 ), AGRP_HUMAN (O00253 ), AGRP_MOUSE (P56473 ), AGRP_PIG (Q9TU18 ), ASIP_BOVIN (Q29414 ), ASIP_CALGE (A1YL78 ), ASIP_CALGO (A1YL80 ), ASIP_CALJA (A1YL77 ), ASIP_CALPY (A1YL79 ), ASIP_CANLF (Q5UK76 ), ASIP_CERMI (Q1XGU9 ), ASIP_CHLAE (Q1XGV1 ), ASIP_COLPO (Q1XGU5 ), ASIP_ERYPA (Q1XGV0 ), ASIP_FELCA (Q865F0 ), ASIP_GORGO (Q1XGV5 ), ASIP_HORSE (Q95MP2 ), ASIP_HUMAN (P42127 ), ASIP_LEOCY (A1YL81 ), ASIP_LEORO (A1YL82 ), ASIP_MACAR (A8CEM9 ), ASIP_MACAS (A8CEN3 ), ASIP_MACCY (A8CEM1 ), ASIP_MACFA (Q1XGV3 ), ASIP_MACFU (A8CEM0 ), ASIP_MACHE (A8CEM5 ), ASIP_MACMR (A8CEM4 ), ASIP_MACMU (A1YL67 ), ASIP_MACNE (A1YL69 ), ASIP_MACNG (A1YL68 ), ASIP_MACNR (A8CEM7 ), ASIP_MACRA (Q1XGV2 ), ASIP_MACSI (A8CEN1 ), ASIP_MACSL (A8CEM8 ), ASIP_MACSY (A1YL66 ), ASIP_MOUSE (Q03288 ), ASIP_PANPA (Q1XGV6 ), ASIP_PANTR (Q1XGV7 ), ASIP_PAPAN (A1YL70 ), ASIP_PIG (Q6ZYM3 ), ASIP_PONPY (Q1XGV4 ), ASIP_RAT (Q99JA2 ), ASIP_SEMEN (Q1XGU8 ), ASIP_TRAAU (A1YL72 ), ASIP_TRACR (Q1XGU6 ), ASIP_TRAFR (A1YL74 ), ASIP_TRAOB (Q1XGU7 ), ASIP_VULVU (P79407 )» more
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| UniProtKB/Swiss-Prot False negative sequences |
10 sequences
TXD01_LYCSI (B6DD19 ), TXD02_LYCSI (B6DD20 ), TXD03_LYCSI (B6DD21 ), TXD04_LYCSI (B6DD22 ), TXD05_LYCSI (B6DD23 ), TXD06_LYCSI (B6DD24 ), TXD07_LYCSI (B6DD25 ), TXD08_LYCSI (B6DD26 ), TXD09_LYCSI (B6DD27 ), TXD10_LYCSI (B6DD28 )» more |
| PDB [Detailed view] |
6 PDB
1HYK; 1MR0; 1Y7J; 1Y7K; 2KZA; 2L1J |
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