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annotation rule: PRU00494

General rule information [?]

Accession PRU00494
Dates 16-NOV-2005 (Created)
21-NOV-2019 (Last updated, Version 6)
Data class Domain
Predictors PROSITE; PS51150; AGOUTI_2
Name Agouti domain
Function The agouti domain is a Cys-rich C-terminal module, which is responsible for melanocortin receptor binding activity in vitro.

Propagated annotation [?]

Cross-references [?]


Keywords [?]

case <FTTag:disulf>
end case

Features [?]

From: PS51150
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Agouti #        
DISULFID     1     16           disulf   C-x*-C  
DISULFID     8     22           disulf   C-x*-C  
DISULFID     15     33           disulf   C-x*-C  
DISULFID     19     40           disulf   C-x*-C  
DISULFID     24     31           disulf   C-x*-C  

Additional information [?]

Size range 35-45 amino acids
Related rules None
Repeats 1
Topology Not cytoplasmic
Example O00253 (AGRP_HUMAN)
Eukaryota; Metazoa; Craniata


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]