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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00494


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00494
General rule information [?]

Accession PRU00494
Dates 16-NOV-2005 (Created)
21-NOV-2019 (Last updated, Version 7)
Data class Domain;
Predictors PROSITE; PS51150; AGOUTI_2
Name Agouti domain
Function The agouti domain is a Cys-rich C-terminal module, which is responsible for melanocortin receptor binding activity in vitro.
Scope(s) Eukaryota
Metazoa
Example(s) O00253;

Propagated annotation [?]

Keywords [?]

case <FTTag:disulf>
Disulfide bond
end case

Cross-references [?]

PROSITE PS60024; AGOUTI_1; 1;

Features [?]

From: PS51150
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Agouti #"
DISULFID 1 16 disulf C-x*-C
DISULFID 8 22 disulf C-x*-C
DISULFID 15 33 disulf C-x*-C
DISULFID 19 40 disulf C-x*-C
DISULFID 24 31 disulf C-x*-C

Additional information [?]

Size range 35-45 amino acids
Related rules None
Fusion None
Repeats 1
Topology Not cytoplasmic

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]