ProRule PRU00494
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU00494 |
| Accession | PRU00494 |
| Dates | 16-NOV-2005 (Created)
21-NOV-2019 (Last updated, Version 6) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51150; AGOUTI_2 |
Name | Agouti domain |
| Function | The agouti domain is a Cys-rich C-terminal module, which is responsible for melanocortin receptor binding activity in vitro. |
| Scope(s) |
Eukaryota Metazoa |
| Example(s) | O00253 (AGRP_HUMAN); |
Propagated annotation
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Keywords
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| case <FTTag:disulf> | |
| Disulfide bond | |
| end case | |
Cross-references
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| PROSITE | PS60024; AGOUTI_1; 1; |
Features
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| From: PS51150 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Agouti #" | |||||||||
| DISULFID | 1 | 16 | disulf | C-x*-C | ||||||||
| DISULFID | 8 | 22 | disulf | C-x*-C | ||||||||
| DISULFID | 15 | 33 | disulf | C-x*-C | ||||||||
| DISULFID | 19 | 40 | disulf | C-x*-C | ||||||||
| DISULFID | 24 | 31 | disulf | C-x*-C | ||||||||
Additional information
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| Size range | 35-45 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Not cytoplasmic |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [58] All [ 58 ]
- Retrieve set of proteins with 3D structure for this domain